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Ophthalmology

How Is a Loa loa African Eye Worm Surgically Removed?

At a Glance

A Loa loa eye worm can be safely removed by an ophthalmologist during a quick, painless procedure. However, surgery only relieves eye discomfort and does not cure the systemic loiasis infection. Blood tests are required before starting full body medication to safely eliminate remaining worms.

Seeing a worm moving across your eye is a highly distressing experience, but if the worm is visible just beneath the clear surface layer of your eye, a doctor can often remove it with a minor surgical procedure [1][2]. Do not try to rub, scratch, or flush your eye out—the worm is trapped beneath a membrane, and rubbing could cause injury.

Because the worm can move quickly and may hide again before you reach a medical professional, it is highly recommended to safely take a clear photo or video of your eye as soon as you spot it [3]. This provides your care team with immediate proof of the infection, even if the worm has migrated out of view by the time you sit in the exam chair.

For the immediate removal, you will likely need to see an ophthalmologist (a specialist in eye and vision care) or go to an emergency room with an ophthalmologist on call. However, for your comprehensive long-term treatment, you will need to see an infectious disease specialist [1].

How Surgical Extraction Works

If the Loa loa worm is actively visible under the conjunctiva (the clear membrane that covers the white part of your eye and the inside of your eyelids), an eye specialist can physically extract it [1][2].

The process is generally a straightforward, localized procedure that typically takes less than 30 minutes:

  • Numbing drops: The doctor will apply local anesthesia drops to your eye to completely numb the surface, ensuring you will not feel pain during the removal [1].
  • Minor extraction: Using specialized medical instruments, the doctor will make a tiny opening in the conjunctiva, grasp the worm, and carefully pull it out intact [1][2].
  • Post-care: Your doctor may prescribe antibiotic eye drops afterward to prevent bacterial infection at the tiny extraction site.

This extraction provides immediate physical relief and addresses the immediate discomfort in your eye [4].

Why Surgery Does Not Cure Loiasis

While having the worm removed from your eye is a huge relief, it does not mean the overall disease (loiasis) is fully cured. Removing a single visible worm only addresses the immediate ocular symptoms [4][1].

Loa loa is a systemic infection, meaning the parasites live and travel throughout your body’s tissues [4][5]. Even after a successful eye surgery, it is very likely you still have other adult worms hidden in the deeper tissues of your body (which can cause itchy “Calabar swellings” on the skin), as well as thousands of microfilariae (microscopic baby worms) circulating in your blood [4][6].

To fully cure the disease and prevent future worms from migrating to your eyes or skin, your doctor will need to prescribe systemic antiparasitic medications, which work throughout your entire body to eliminate the remaining parasites [4][7].

Next Steps Before Starting Medication

If you have a worm removed, your doctor will likely not prescribe antiparasitic pills immediately on the spot. Before starting systemic treatment, your care team must run blood tests to determine your microfilarial load (the exact density of microscopic parasites currently in your bloodstream) [8][9]. These test results can take a few days to process.

If the number of microscopic worms in your blood is exceptionally high, starting standard medication immediately can trigger severe side effects, such as dangerous brain inflammation (encephalopathy), as the medications rapidly kill off the parasites [10][11].

If your test reveals a high parasite load, do not panic. Your doctors have safe protocols to handle this. They may use specialized blood-filtering procedures (apheresis) to safely remove the baby worms from your blood before starting medication, or they may use specific alternative drugs to lower the load gradually [12][13]. Your doctor will carefully evaluate your bloodwork to formulate a safe, targeted treatment plan [7].

Common questions in this guide

What should I do if I see a worm moving in my eye?
Do not rub, scratch, or try to flush your eye. Instead, try to safely take a clear photo or video of the worm right away to show your care team. Then, seek immediate medical attention from an ophthalmologist or an emergency room for professional removal.
How is a Loa loa eye worm removed?
The extraction is a straightforward procedure that usually takes less than 30 minutes. An eye specialist will use local numbing drops so you don't feel pain, make a tiny opening in the clear membrane of your eye, and carefully pull the worm out intact.
Am I fully cured after the doctor removes the worm from my eye?
No, surgery does not cure the disease. Loiasis is a systemic infection, meaning you likely have other adult worms and microscopic baby worms hidden in your body's tissues and bloodstream. You will need systemic medication to fully eliminate the parasites.
Why do I need a blood test before starting antiparasitic medication?
Doctors must first run blood tests to check the density of microscopic baby worms in your bloodstream. Starting medication when you have a very high parasite load can trigger severe and dangerous side effects, such as brain inflammation, as the drugs rapidly kill the worms.

Questions to Ask Your Doctor

Curated prompts to bring to your next appointment.

  1. 1.Can you refer me to an infectious disease specialist with experience in treating filarial infections?
  2. 2.What is my microfilarial load, and how does that number affect the safety of my medication plan?
  3. 3.If my microfilarial load is high, what steps or procedures will we take to lower it safely before starting standard antiparasitic drugs?
  4. 4.What should I do if I feel another worm migrating in my eye before my blood test results come back?

Questions For You

Tap a prompt to share your answer — we'll use it plus this page's context to start a tailored conversation.

References

References (13)
  1. 1

    Loa loa in the vitreous cavity of the eye.

    Nayak B, Sinha S, Nayak L

    BMJ case reports 2016; (2016()).

    PMID: 26746839
  2. 2

    Anterior Chamber Live Loa loa: Case Report.

    Kagmeni G, Cheuteu R, Bilong Y, Wiedemann P

    Clinical medicine insights. Case reports 2016; (9()):55-6 doi:10.4137/CCRep.S40012.

    PMID: 27441005
  3. 3

    Burden of disease in Gabon caused by loiasis: a cross-sectional survey.

    Veletzky L, Hergeth J, Stelzl DR, et al.

    The Lancet. Infectious diseases 2020; (20(11)):1339-1346 doi:10.1016/S1473-3099(20)30256-5.

    PMID: 32585133
  4. 4

    An Adult Loa loa Worm in the Upper Eyelid: An Atypical Presentation of Loiasis in the United States.

    Rodriguez L, White JM, Richards NQ, et al.

    Case reports in ophthalmological medicine 2021; (2021()):6630875 doi:10.1155/2021/6630875.

    PMID: 33959400
  5. 5

    Presence of adult Loa loa in the anterior chamber of the eye along with microfilaremia from nonendemic region: A rare presentation from India.

    Kumari V, Ahmad S, Singh A, Banerjee T

    Tzu chi medical journal 2019; (31(4)):283-285 doi:10.4103/tcmj.tcmj_227_18.

    PMID: 31867260
  6. 6

    Loiasis in sub-Saharan migrants living in Spain with emphasis of cases from Equatorial Guinea.

    Puente S, Ramírez-Olivencia G, Lago M, et al.

    Infectious diseases of poverty 2020; (9(1)):16 doi:10.1186/s40249-020-0627-4.

    PMID: 32029005
  7. 7

    Diagnosis, management and prevention of loiasis: guideline of the German Society for Tropical Medicine, Travel Medicine, and Global Health (DTG).

    Ramharter M, Schlabe S, Hübner MP, et al.

    Infection 2025; (53(3)):851-872 doi:10.1007/s15010-024-02443-2.

    PMID: 40397272
  8. 8

    A novel antigen biomarker for detection of high-level of Loa loa microfilaremia.

    Greene SE, Huang Y, Fischer K, et al.

    PLoS neglected tropical diseases 2024; (18(9)):e0012461 doi:10.1371/journal.pntd.0012461.

    PMID: 39226306
  9. 9

    Colorimetric and Real-Time Loop-Mediated Isothermal Amplification (LAMP) for Detection of Loa loa DNA in Human Blood Samples.

    Febrer-Sendra B, Fernández-Soto P, Crego-Vicente B, et al.

    Diagnostics (Basel, Switzerland) 2022; (12(5)) doi:10.3390/diagnostics12051079.

    PMID: 35626235
  10. 10

    Albendazole-related Loa Loa encephalopathy.

    Métais A, Michalak S, Rousseau A

    IDCases 2021; (23()):e01033 doi:10.1016/j.idcr.2020.e01033.

    PMID: 33489754
  11. 11

    Encephalopathy in a patient with loiasis treated with albendazole: A case report.

    Volpicelli L, De Angelis M, Morano A, et al.

    Parasitology international 2020; (75()):102006 doi:10.1016/j.parint.2019.102006.

    PMID: 31676328
  12. 12

    Safety and effectiveness of apheresis in the treatment of infectious diseases: A systematic review.

    Odedra A, Lalloo DG, Kennedy G, et al.

    The Journal of infection 2019; (79(6)):513-520 doi:10.1016/j.jinf.2019.09.014.

    PMID: 31622632
  13. 13

    Therapeutic apheresis using a mononuclear cell program to lower the microfilaria burden of a 23-year-old African woman with loiasis.

    Zhao Y, Alexander B, Bailey JA, et al.

    Journal of clinical apheresis 2017; (32(3)):200-202 doi:10.1002/jca.21479.

    PMID: 27302472

This page provides educational information about the surgical removal of Loa loa eye worms. It is not a substitute for immediate, professional medical care from an ophthalmologist or infectious disease specialist.

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