Skip to content
PubMed This is a summary of 12 peer-reviewed journal articles Updated
Colorectal Surgery

Understanding Your Diagnosis: Anal Fistula Basics

At a Glance

An anal fistula is a highly treatable tunnel that forms between an infected anal gland and the outside skin. While it can cause pain and emotional distress, modern treatments, including muscle-sparing surgeries, are extremely effective at healing the fistula while protecting your bowel control.

Finding out you have an anal fistula can be overwhelming. It is a condition that often brings a mix of sharp physical pain and significant emotional distress [1]. Many people feel a deep sense of embarrassment or isolation because of where the problem is located [2]. If you are feeling this way, please know that you are not alone. This is a well-understood medical condition that affects many people, and there are clear, effective paths toward healing.

Understanding the “Why”: The Cryptoglandular Hypothesis

Most anal fistulas are not caused by anything you did wrong. The leading scientific explanation for why they happen is called the cryptoglandular hypothesis [3].

Inside your anal canal, there are small glands called anal glands (or proctodeal glands) [3]. These glands normally drain into the anal canal through tiny openings called crypts [3]. The hypothesis suggests that:

  1. Blockage and Infection: One of these glands becomes blocked, trapping bacteria inside [4].
  2. Abscess Formation: This blockage leads to an infection and the buildup of pus, known as an abscess [5].
  3. Fistula Creation: As the body tries to drain this infection, it may create a small tunnel (the fistula) from the gland inside the canal to the skin on the outside [3].

While anyone can develop this condition, it is most frequently diagnosed in young and middle-aged adults, and it is significantly more common in males than in females [6][7].

Three Stabilizing Facts

When you are first diagnosed, your mind may jump to the worst-case scenarios. Here are three grounding facts to help you navigate the early days of your diagnosis:

  1. It is highly treatable: While a fistula rarely heals on its own, medical procedures are very effective. For “simple” fistulas, traditional treatments like a fistulotomy (opening the tunnel so it can heal from the inside out) have very high success rates [8][9].
  2. Muscle-sparing options exist: Modern medicine has developed “sphincter-sparing” techniques—such as the LIFT procedure or VAAFT (video-assisted treatment)—designed to fix the fistula while protecting the muscles responsible for bowel control [10][11].
  3. The pain is manageable: The intense pressure and pain often caused by the initial abscess usually improve significantly once the tract is properly drained or treated [2].

Validating Your Experience

It is completely normal to feel a “psychological burden” when dealing with a fistula [2]. The constant drainage, the need to wear pads, and the fear of an “accident” can impact your self-perception and quality of life [1][2]. Doctors who specialize in this area—colorectal surgeons—see these conditions every day. They understand the sensitivity of the situation and are focused on helping you regain your comfort and confidence.

Successful treatment has been shown to significantly improve a patient’s quality of life and mental well-being, even if the recovery process takes time [2][12]. You are taking the first step by learning about the condition and preparing to advocate for your care.

Common questions in this guide

What causes an anal fistula?
Most anal fistulas are caused by a blocked anal gland, a process known as the cryptoglandular hypothesis. The blockage traps bacteria, leading to an infection and an abscess, which then creates a small tunnel from the inside of the anal canal to the skin outside.
Can an anal fistula heal on its own without surgery?
An anal fistula rarely heals on its own. Medical procedures, such as a fistulotomy or sphincter-sparing techniques, are necessary and highly effective at treating the condition so it can heal from the inside out.
Will surgery for an anal fistula affect my bowel control?
Bowel control is a common concern, but modern medicine offers sphincter-sparing procedures like LIFT and VAAFT. These specialized techniques are specifically designed to treat the fistula while protecting the sphincter muscles responsible for bowel continence.
What are the common symptoms of an anal fistula?
Common symptoms include sharp physical pain, continuous or intermittent drainage of fluid or pus, and itching around the anus. The pain and pressure usually improve significantly once the fistula is properly treated and drained.
What is the difference between a simple and complex anal fistula?
A simple fistula is more straightforward and often treated successfully with a fistulotomy. A complex fistula generally involves more of the sphincter muscle or follows a complicated path, requiring specialized, muscle-sparing surgical approaches or a seton placement.

Questions to Ask Your Doctor

Curated prompts to bring to your next appointment.

  1. 1.Based on my imaging or exam, do I have a 'simple' or 'complex' fistula?
  2. 2.What is the exact path of my fistula, and does it involve my sphincter muscles?
  3. 3.Which surgical approach do you recommend for my specific case—a sphincter-cutting or a sphincter-sparing procedure?
  4. 4.What is your personal success rate and complication rate for the procedure you are recommending?
  5. 5.If we use a seton, how long will it need to stay in place, and what will the day-to-day management look like?
  6. 6.How will this treatment affect my bowel control (continence) in the long term?

Questions For You

Tap a prompt to share your answer — we'll use it plus this page's context to start a tailored conversation.

References

References (12)
  1. 1

    Quality of life with anal fistula.

    Owen HA, Buchanan GN, Schizas A, et al.

    Annals of the Royal College of Surgeons of England 2016; (98(5)):334-8 doi:10.1308/rcsann.2016.0136.

    PMID: 27087327
  2. 2

    Anal incontinence and quality of life following operative treatment of simple cryptoglandular fistula-in-ano: a prospective study.

    Jayarajah U, Wickramasinghe DP, Samarasekera DN

    BMC research notes 2017; (10(1)):572 doi:10.1186/s13104-017-2895-z.

    PMID: 29115980
  3. 3

    Current concepts in the pathogenesis of cryptoglandular perianal fistula.

    Włodarczyk M, Włodarczyk J, Sobolewska-Włodarczyk A, et al.

    The Journal of international medical research 2021; (49(2)):300060520986669 doi:10.1177/0300060520986669.

    PMID: 33595349
  4. 4

    Curing cryptoglandular anal fistulas-Is it possible without surgery?

    Wu C, Mei Z, Wang Z

    Heliyon 2025; (11(1)):e41297 doi:10.1016/j.heliyon.2024.e41297.

    PMID: 39811351
  5. 5

    Formation rate of secondary anal fistula after incision and drainage of perianal Sepsis and analysis of risk factors.

    He Z, Du J, Wu K, et al.

    BMC surgery 2020; (20(1)):94 doi:10.1186/s12893-020-00762-3.

    PMID: 32375721
  6. 6

    [Clinical characteristics and risk factors for recurrence of anal fistula patients].

    Li J, Yang W, Huang Z, et al.

    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 2016; (19(12)):1370-1374.

    PMID: 28000193
  7. 7

    Clinicopathological determinants of recurrence after surgical treatment of fistula-in-ano in a Ghanaian teaching hospital.

    Bediako-Bowan AAA, Naalane N, Kumassah PK, Dakubo JCB

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 2022; (24(10)):1197-1203 doi:10.1111/codi.16168.

    PMID: 35502697
  8. 8

    Fistulotomy versus Fistulectomy for Fistula-in-Ano: A Randomized Prospective Study.

    Hiremath SCS, Patil R

    Surgery journal (New York, N.Y.) 2022; (8(4)):e336-e340 doi:10.1055/s-0042-1758633.

    PMID: 36425406
  9. 9

    Fistulotomy versus fistulectomy for simple fistula-in-ano: a systematic review and meta-analysis of randomized controlled trials.

    Quinn R, Peacock A, Lendzion RJ

    ANZ journal of surgery 2025; (95(6)):1074-1090 doi:10.1111/ans.70095.

    PMID: 40125894
  10. 10

    Comparative study between intersphinecteric ligation of perianal fistula versus conventional fistulotomy with or without seton in the treatment of perianal fistula: A prospective randomized controlled trial.

    Al Sebai OI, Ammar MS, Mohamed SH, El Balshy MA

    Annals of medicine and surgery (2012) 2021; (61()):180-184 doi:10.1016/j.amsu.2020.12.014.

    PMID: 33489105
  11. 11

    Video-Assisted Anal Fistula Treatment (VAAFT) in Cryptoglandular fistula-in-ano: A systematic review and proportional meta-analysis.

    Garg P, Singh P

    International journal of surgery (London, England) 2017; (46()):85-91 doi:10.1016/j.ijsu.2017.08.582.

    PMID: 28882770
  12. 12

    The Impact of Crohn's Perianal Fistula on Quality of Life: Results of an International Patient Survey.

    Spinelli A, Yanai H, Girardi P, et al.

    Crohn's & colitis 360 2023; (5(3)):otad036 doi:10.1093/crocol/otad036.

    PMID: 37529012

This page explains anal fistula basics for educational purposes. Your colorectal surgeon is the best source for diagnosing your specific condition and discussing the most appropriate treatment options.

Get notified when new evidence is published on Anal fistula.

We monitor PubMed for new peer-reviewed studies on this topic and email a short summary when something meaningful changes.