Research & Literature

Follow-up of 316 molecularly defined pediatric long-QT syndrome patients: clinical course, treatments, and side effects.

Koponen M, Marjamaa A, Hiippala A, et al.

Circulation. Arrhythmia and electrophysiology 2015; (8(4)):815-23 doi:10.1161/CIRCEP.114.002654.

A Case for Inclusion of Genetic Counselors in Cardiac Care.

Arscott P, Caleshu C, Kotzer K, et al.

Cardiology in review 2016; (24(2)):49-55 doi:10.1097/CRD.0000000000000081.

Prolonged QT: A rare cause of cardiac arrest.

Carlquist J

JAAPA : official journal of the American Academy of Physician Assistants 2015; (28(8)) doi:10.1097/01.JAA.0000466588.56337.68.

Pronounced Shortening of QT Interval With Mexiletine Infusion Test in Patients With Type 3 Congenital Long QT Syndrome.

Funasako M, Aiba T, Ishibashi K, et al.

Circulation journal : official journal of the Japanese Circulation Society 2016; (80(2)):340-5 doi:10.1253/circj.CJ-15-0984.

Implantable cardioverter-defibrillator explantation for overdiagnosed or overtreated congenital long QT syndrome.

Gaba P, Bos JM, Cannon BC, et al.

Heart rhythm 2016; (13(4)):879-85.

Patient Outcomes From a Specialized Inherited Arrhythmia Clinic.

Adler A, Sadek MM, Chan AY, et al.

Circulation. Arrhythmia and electrophysiology 2016; (9(1)):e003440.

Investigating the effect of 28 BRCA1 and BRCA2 mutations on their related transcribed mRNA.

Quiles F, Menéndez M, Tornero E, et al.

Breast cancer research and treatment 2016; (155(2)):253-60 doi:10.1007/s10549-015-3676-9.

Gene-Specific Therapy With Mexiletine Reduces Arrhythmic Events in Patients With Long QT Syndrome Type 3.

Mazzanti A, Maragna R, Faragli A, et al.

Journal of the American College of Cardiology 2016; (67(9)):1053-1058 doi:10.1016/j.jacc.2015.12.033.

The evolution of sports participation guidelines and the influence of genotype-phenotype correlation in long QT syndrome.

Furst ML, Aziz PF

Trends in cardiovascular medicine 2016; (26(8)):690-697 doi:10.1016/j.tcm.2016.04.013.

A new paradigm for predicting risk of Torsades de Pointes during drug development: Commentary on: "Improved prediction of drug-induced Torsades de Pointes through simulations of dynamics and machine learning algorithms".

McCauley MD, Darbar D

Clinical pharmacology and therapeutics 2016; (100(4)):324-6 doi:10.1002/cpt.408.

The Long QT Syndrome: A Review and Mortality Analysis.

Rigatti SJ

Journal of insurance medicine (New York, N.Y.) 2015; (45(2)):81-7 doi:10.17849/insm-45-02-081-087.1.

Left cardiac sympathetic denervation: An important treatment option for patients with hereditary ventricular arrhythmias.

Cho Y

Journal of arrhythmia 2016; (32(5)):340-343 doi:10.1016/j.joa.2015.08.002.

Molecular autopsy in victims of inherited arrhythmias.

Semsarian C, Ingles J

Journal of arrhythmia 2016; (32(5)):359-365 doi:10.1016/j.joa.2015.09.010.

Molecular Pathophysiology of Congenital Long QT Syndrome.

Bohnen MS, Peng G, Robey SH, et al.

Physiological reviews 2017; (97(1)):89-134 doi:10.1152/physrev.00008.2016.

Management of Patients with Long QT Syndrome.

Cho Y

Korean circulation journal 2016; (46(6)):747-752 doi:10.4070/kcj.2016.46.6.747.

Reproducibility of corrected QT interval in pediatric genotyped long QT syndrome.

Ogawa Y, Tanaka T, Kido S

Pediatrics international : official journal of the Japan Pediatric Society 2016; (58(11)):1246-1248 doi:10.1111/ped.13120.

Identification of KCNQ1 compound heterozygous mutations in three Chinese families with Jervell and Lange-Nielsen Syndrome.

Wang C, Lu Y, Cheng J, et al.

Acta oto-laryngologica 2017; (137(5)):522-528 doi:10.1080/00016489.2016.1260156.

Avoiding sports-related sudden cardiac death in children with congenital channelopathy : Recommendations for sports activities.

Lang CN, Steinfurt J, Odening KE

Herz 2017; (42(2)):162-170 doi:10.1007/s00059-017-4549-2.

Effect of Age and Sex on the QTc Interval in Children and Adolescents With Type 1 and 2 Long-QT Syndrome.

Vink AS, Clur SB, Geskus RB, et al.

Circulation. Arrhythmia and electrophysiology 2017; (10(4)) doi:10.1161/CIRCEP.116.004645.

Torsade de pointes arrhythmias arise at the site of maximal heterogeneity of repolarization in the chronic complete atrioventricular block dog.

Dunnink A, Stams TRG, Bossu A, et al.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2017; (19(5)):858-865 doi:10.1093/europace/euw087.

Effect of age and gender on the QTc-interval in healthy individuals and patients with long-QT syndrome.

Vink AS, Clur SB, Wilde AAM, Blom NA

Trends in cardiovascular medicine 2018; (28(1)):64-75 doi:10.1016/j.tcm.2017.07.012.

Identification and characterization of a novel recessive KCNQ1 mutation associated with Romano-Ward Long-QT syndrome in two Iranian families.

Zafari Z, Dalili M, Zeinali S, et al.

Journal of electrocardiology 2017; (50(6)):912-918 doi:10.1016/j.jelectrocard.2017.07.012.

Effectiveness of beta-blockers depending on the genotype of congenital long-QT syndrome: A meta-analysis.

Ahn J, Kim HJ, Choi JI, et al.

PloS one 2017; (12(10)):e0185680 doi:10.1371/journal.pone.0185680.

Late-onset severe long QT syndrome.

Asatryan B, Schaller A, Bartholdi D, Medeiros-Domingo A

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 2018; (23(4)):e12517 doi:10.1111/anec.12517.

Interplay Between Genetic Substrate, QTc Duration, and Arrhythmia Risk in Patients With Long QT Syndrome.

Mazzanti A, Maragna R, Vacanti G, et al.

Journal of the American College of Cardiology 2018; (71(15)):1663-1671 doi:10.1016/j.jacc.2018.01.078.

Wearable cardioverter defibrillators for patients with long QT syndrome.

Owen HJ, Bos JM, Ackerman MJ

International journal of cardiology 2018; (268()):132-136 doi:10.1016/j.ijcard.2018.04.002.

Electrocardiogram screening of deaf children for long QT syndrome: An Egyptian experience.

Gouda S, Saif MQ, Shabana M, et al.

Pacing and clinical electrophysiology : PACE 2018; (41(11)):1414-1419 doi:10.1111/pace.13484.

Long-QT Syndrome and Competitive Sports.

Schnell F, Behar N, Carré F

Arrhythmia & electrophysiology review 2018; (7(3)):187-192 doi:10.15420/aer.2018.39.3.

The role of mexiletine in the management of long QT syndrome.

Li G, Zhang L

Journal of electrocardiology 2018; (51(6)):1061-1065 doi:10.1016/j.jelectrocard.2018.08.035.

Clinical and genetic profile of congenital long QT syndrome in Hong Kong: a 20-year experience in paediatrics.

Kwok SY, Liu AP, Chan CY, et al.

Hong Kong medical journal = Xianggang yi xue za zhi 2018; (24(6)):561-570 doi:10.12809/hkmj187487.

All the things that we should think about if we want to diagnose the long QT accurately.

Cay S, Ozeke O, Ozcan F, et al.

Pacing and clinical electrophysiology : PACE 2019; (42(2)):293 doi:10.1111/pace.13575.

Determination and Interpretation of the QT Interval.

Vink AS, Neumann B, Lieve KVV, et al.

Circulation 2018; (138(21)):2345-2358 doi:10.1161/CIRCULATIONAHA.118.033943.

Title not available

Ildarova RA, Shkolnikova MA, Termosesov SA

Kardiologiia 2018; (58(12)):52-58 doi:10.18087/cardio.2018.12.10191.

Arrhythmias due to Inherited and Acquired Abnormalities of Ventricular Repolarization.

Locati ET, Bagliani G, Cecchi F, et al.

Cardiac electrophysiology clinics 2019; (11(2)):345-362 doi:10.1016/j.ccep.2019.02.009.

A case of congenital long QT syndrome, type 8, undergoing laparoscopic hysterectomy with general anesthesia.

Chang SL, Chang CT, Hung WT, Chen LK

Taiwanese journal of obstetrics & gynecology 2019; (58(4)):552-556 doi:10.1016/j.tjog.2019.05.031.

Inherited Cardiac Arrhythmias and Channelopathies.

Kline J, Costantini O

The Medical clinics of North America 2019; (103(5)):809-820 doi:10.1016/j.mcna.2019.05.001.

Compound and heterozygous mutations of KCNQ1 in long QT syndrome with familial history of unexplained sudden death: Identified by analysis of whole exome sequencing and predisposing genes.

Lin Y, Zhao T, He S, et al.

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 2020; (25(1)):e12694 doi:10.1111/anec.12694.

Left cardiac sympathetic denervation in the management of long QT syndrome and catecholaminergic polymorphic ventricular tachycardia: A meta-regression.

Sgrò A, Drake TM, Lopez-Ayala P, Phan K

Congenital heart disease 2019; (14(6)):1102-1112 doi:10.1111/chd.12855.

The impact of age on long QT syndrome.

Guettler N, Rajappan K, Nicol E

Aging 2019; (11(24)):11795-11796 doi:10.18632/aging.102623.

An International Multicenter Evaluation of Type 5 Long QT Syndrome: A Low Penetrant Primary Arrhythmic Condition.

Roberts JD, Asaki SY, Mazzanti A, et al.

Circulation 2020; (141(6)):429-439 doi:10.1161/CIRCULATIONAHA.119.043114.

Pre-Test Probability and Genes and Variants of Uncertain Significance in Familial Long QT Syndrome.

Waddell-Smith KE, Skinner JR, Bos JM

Heart, lung & circulation 2020; (29(4)):512-519 doi:10.1016/j.hlc.2019.12.011.

A Review of Long QT Syndrome: Everything a Hospitalist Should Know.

Sharma N, Cortez D, Disori K, et al.

Hospital pediatrics 2020; (10(4)):369-375 doi:10.1542/hpeds.2019-0139.

Left cardiac sympathetic denervation reduces skin sympathetic nerve activity in patients with long QT syndrome.

Han J, Ackerman MJ, Moir C, et al.

Heart rhythm 2020; (17(10)):1639-1645 doi:10.1016/j.hrthm.2020.03.023.

Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome.

Lahrouchi N, Tadros R, Crotti L, et al.

Circulation 2020; (142(4)):324-338 doi:10.1161/CIRCULATIONAHA.120.045956.

Structures Illuminate Cardiac Ion Channel Functions in Health and in Long QT Syndrome.

Brewer KR, Kuenze G, Vanoye CG, et al.

Frontiers in pharmacology 2020; (11()):550 doi:10.3389/fphar.2020.00550.

The importance of the epinephrine provocation test for the hidden type-1 congenital long QT syndrome.

Atici A, Asoğlu R, Barman HA, Sahin I

Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 2020; (48(4)):434-438 doi:10.5543/tkda.2020.40480.

Inducible torsades de pointes during an acute face immersion test in an adolescent with type 2 long QT syndrome.

Muneuchi J, Sugitani Y, Watanabe M

Cardiology in the young 2020; (30(8)):1171-1172 doi:10.1017/S1047951120002176.

QT correction using Bazett's formula remains preferable in long QT syndrome type 1 and 2.

Dahlberg P, Diamant UB, Gilljam T, et al.

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 2021; (26(1)):e12804 doi:10.1111/anec.12804.

Video-thoracoscopic left cardiac sympathetic denervation for long-QT syndrome.

Lampridis S, Antonopoulos A, Kakos C, et al.

Asian cardiovascular & thoracic annals 2021; (29(3)):186-190 doi:10.1177/0218492320971492.

Problems with Bazett QTc correction in paediatric screening of prolonged QTc interval.

Andršová I, Hnatkova K, Helánová K, et al.

BMC pediatrics 2020; (20(1)):558 doi:10.1186/s12887-020-02460-8.

Mechanisms underlying age-associated manifestation of cardiac sodium channel gain-of-function.

Nowak MB, Poelzing S, Weinberg SH

Journal of molecular and cellular cardiology 2021; (153()):60-71 doi:10.1016/j.yjmcc.2020.12.008.

Potential overdiagnosis of long QT syndrome using exercise stress and QT stand testing in children and adolescents with a low probability of disease.

Roston TM, De Souza AM, Romans HV, et al.

Journal of cardiovascular electrophysiology 2021; (32(2)):500-506 doi:10.1111/jce.14865.

Use of Artificial Intelligence and Deep Neural Networks in Evaluation of Patients With Electrocardiographically Concealed Long QT Syndrome From the Surface 12-Lead Electrocardiogram.

Bos JM, Attia ZI, Albert DE, et al.

JAMA cardiology 2021; (6(5)):532-538 doi:10.1001/jamacardio.2020.7422.

Long QT Syndrome KCNH2 Variant Induces hERG1a/1b Subunit Imbalance in Patient-Specific Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Feng L, Zhang J, Lee C, et al.

Circulation. Arrhythmia and electrophysiology 2021; (14(4)):e009343 doi:10.1161/CIRCEP.120.009343.

Mexiletine Shortened QT Interval and Reduced Ventricular Arrhythmias in a Pedigree of Type 2 Long QT Syndrome Combined with Left Ventricular Non-Compaction.

Xu B, Li K, Liu F, et al.

International heart journal 2021; (62(2)):427-431 doi:10.1536/ihj.20-518.

Diagnosis, management and therapeutic strategies for congenital long QT syndrome.

Wilde AAM, Amin AS, Postema PG

Heart (British Cardiac Society) 2022; (108(5)):332-338 doi:10.1136/heartjnl-2020-318259.

Long QT syndrome - Bench to bedside.

Ponce-Balbuena D, Deschênes I

Heart rhythm O2 2021; (2(1)):89-106 doi:10.1016/j.hroo.2021.01.006.

Genetic and Molecular Aspects of Drug-Induced QT Interval Prolongation.

Baracaldo-Santamaría D, Llinás-Caballero K, Corso-Ramirez JM, et al.

International journal of molecular sciences 2021; (22(15)) doi:10.3390/ijms22158090.

Mexiletine Treatment for Neonatal LQT3 Syndrome: Case Report and Literature Review.

Bagkaki A, Tsoutsinos A, Hatzidaki E, et al.

Frontiers in pediatrics 2021; (9()):674041 doi:10.3389/fped.2021.674041.

Independent validation and clinical implications of the risk prediction model for long QT syndrome (1-2-3-LQTS-Risk).

Mazzanti A, Trancuccio A, Kukavica D, et al.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2022; (24(4)):614-619 doi:10.1093/europace/euab238.

Induced Pluripotent Stem Cell-Derived Cardiomyocytes with SCN5A R1623Q Mutation Associated with Severe Long QT Syndrome in Fetuses and Neonates Recapitulates Pathophysiological Phenotypes.

Hayama E, Furutani Y, Kawaguchi N, et al.

Biology 2021; (10(10)) doi:10.3390/biology10101062.

Digenic heterozygous mutations of KCNH2 and SCN5A induced young and early-onset long QT syndrome and sinoatrial node dysfunction.

Yang Z, Ma Y, Huang J, et al.

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 2022; (27(1)):e12889 doi:10.1111/anec.12889.

Torsades de pointes in the PACU after outpatient endoscopy: a case report.

Schaar A, Liu M, Patzkowski M

BMC anesthesiology 2021; (21(1)):302 doi:10.1186/s12871-021-01457-9.

Successful Management of a Young Athlete with Type 2 Long QT Syndrome by Genotype-specific Risk Stratification and Bridging Therapy with a Wearable Cardioverter Defibrillator.

Kojima K, Kato K, Fujii Y, et al.

Internal medicine (Tokyo, Japan) 2022; (61(8)):1179-1182 doi:10.2169/internalmedicine.8093-21.

It Is Not Carved in Stone-The Need for a Genetic Reevaluation of Variants in Pediatric Cardiomyopathies.

Westphal DS, Pollmann K, Marschall C, et al.

Journal of cardiovascular development and disease 2022; (9(2)) doi:10.3390/jcdd9020041.

GENESIS: Gene-Specific Machine Learning Models for Variants of Uncertain Significance Found in Catecholaminergic Polymorphic Ventricular Tachycardia and Long QT Syndrome-Associated Genes.

Draelos RL, Ezekian JE, Zhuang F, et al.

Circulation. Arrhythmia and electrophysiology 2022; (15(4)):e010326 doi:10.1161/CIRCEP.121.010326.

Excellent response to β-1 adrenergic receptor blockade (metoprolol) and exercise restriction in high-risk type 1 long QT syndrome. A 22-year follow-up.

Tejeda-Mollinedo W, Díaz-Tostado S, Gómez-Flores J, et al.

HeartRhythm case reports 2022; (8(3)):191-194 doi:10.1016/j.hrcr.2021.12.006.

Overt long QT syndrome in children presenting with seizure disorders in Pakistan.

Rashid U, Virk AO, Nawaz R, et al.

Annals of pediatric cardiology 2021; (14(4)):485-489 doi:10.4103/apc.apc_10_21.

Congenital Long QT Syndrome.

Krahn AD, Laksman Z, Sy RW, et al.

JACC. Clinical electrophysiology 2022; (8(5)):687-706 doi:10.1016/j.jacep.2022.02.017.

Use of a chatbot to increase uptake of cascade genetic testing.

Schmidlen T, Jones CL, Campbell-Salome G, et al.

Journal of genetic counseling 2022; (31(5)):1219-1230 doi:10.1002/jgc4.1592.

CONGENITAL LONG QT SYNDROME: A SYSTEMATIC REVIEW.

Galić E, Bešlić P, Kilić P, et al.

Acta clinica Croatica 2021; (60(4)):739-748 doi:10.20471/acc.2021.60.04.22.

Mutation-Specific Differences in Kv7.1 (KCNQ1) and Kv11.1 (KCNH2) Channel Dysfunction and Long QT Syndrome Phenotypes.

Kekenes-Huskey PM, Burgess DE, Sun B, et al.

International journal of molecular sciences 2022; (23(13)) doi:10.3390/ijms23137389.

Prolonged QT Interval in Athletes: Distinguishing between Pathology and Physiology.

Christou GA, Vlahos AP, Christou KA, et al.

Cardiology 2022; (147(5-6)):578-586 doi:10.1159/000526385.

Effectiveness and safety of mexiletine in patients at risk for (recurrent) ventricular arrhythmias: a systematic review.

van der Ree MH, van Dussen L, Rosenberg N, et al.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2022; (24(11)):1809-1823 doi:10.1093/europace/euac087.

Sex Differences and Utility of Treadmill Testing in Long-QT Syndrome.

Yee LA, Han HC, Davies B, et al.

Journal of the American Heart Association 2022; (11(18)):e025108 doi:10.1161/JAHA.121.025108.

Cerebral Seizures in an Adolescent with Jervell and Lange-Nielsen Syndrome: It May Not Be Epilepsy.

Levaux J, Farhat N, Van Casteren L, et al.

Clinics and practice 2022; (12(5)):677-685 doi:10.3390/clinpract12050070.

Precision medicine for long QT syndrome: patient-specific iPSCs take the lead.

Yu Y, Deschenes I, Zhao MT

Expert reviews in molecular medicine 2023; (25()):e5 doi:10.1017/erm.2022.43.

Sex differences in long QT syndrome.

Díez-Escuté N, Arbelo E, Martínez-Barrios E, et al.

Frontiers in cardiovascular medicine 2023; (10()):1164028 doi:10.3389/fcvm.2023.1164028.

Computational Study on Effect of KCNQ1 P535T Mutation in a Cardiac Ventricular Tissue.

Satish H, Machireddy RR

The Journal of membrane biology 2023; (256(3)):287-297 doi:10.1007/s00232-023-00287-9.

Torsades De Pointes in a 71-Year-Old Female With Normal Qt Interval After Azithromycin Use.

Foster A, Cancarevic I, Haseeb Ul Rasool M, et al.

Cureus 2023; (15(4)):e37653 doi:10.7759/cureus.37653.

Preventing and Treating Torsades de Pointes in the Mother, Fetus and Newborn in the Highest Risk Pregnancies with Inherited Arrhythmia Syndromes.

Wacker-Gussmann A, Eckstein GK, Strasburger JF

Journal of clinical medicine 2023; (12(10)) doi:10.3390/jcm12103379.

Indications for mexiletine in the new ESC guidelines and beyond.

Vamos M, Zsigmond EJ, Hohnloser SH

Expert opinion on pharmacotherapy 2023; (24(12)):1403-1407 doi:10.1080/14656566.2023.2223964.

Autosomal Recessive Long QT Syndrome: Clinical Aspects and Therapy.

Righi D, Porco L, Di Mambro C, et al.

Pediatric cardiology 2023; (44(8)):1736-1740 doi:10.1007/s00246-023-03266-y.

Left cardiac sympathetic denervation in children with Jervell Lange-Nielsen syndrome and drug refractory torsades - A case series.

Bhattacharya D, Namboodiri N, Sreelekshmi MP, et al.

Pacing and clinical electrophysiology : PACE 2023; (46(10)):1197-1202 doi:10.1111/pace.14827.

The 2023 Canadian Cardiovascular Society Clinical Practice Update on Management of the Patient With a Prolonged QT Interval.

Davies RA, Ladouceur VB, Green MS, et al.

The Canadian journal of cardiology 2023; (39(10)):1285-1301 doi:10.1016/j.cjca.2023.06.011.

Calmodulin mutation in long QT syndrome 15 associated with congenital heart defects further complicated by a functional 2:1 atrioventricular block: Management from foetal life to postpartum.

Caruso E, Farruggio S, Guccione P

Indian pacing and electrophysiology journal 2024; (24(3)):150-154 doi:10.1016/j.ipej.2024.01.006.

Exploring the impact of a KCNH2 missense variant on Long QT syndrome: insights into a novel gender-selective, incomplete penetrance inheritance mode.

Chen P, Zampawala Z, Wang H, Wang L

Frontiers in genetics 2024; (15()):1409459 doi:10.3389/fgene.2024.1409459.

The multigenerational impact of long QT syndrome: A Gitxsan perspective.

Huisman LA, Martin S, Ewasiuk E, et al.

Journal of genetic counseling 2025; (34(1)):e1927 doi:10.1002/jgc4.1927.

Identifying genomic variant associated with long QT syndrome type 2 in an ecuadorian mestizo individual: a case report.

Tamayo-Trujillo R, Ibarra-Castillo R, Laso-Bayas JL, et al.

Frontiers in genetics 2024; (15()):1395012 doi:10.3389/fgene.2024.1395012.

Results of comprehensive genetic testing in patients presenting to a multidisciplinary inherited heart disease clinic in India.

Chockalingam P, Geetha TS, Nair S, et al.

Indian heart journal 2024; (76(4)):260-267 doi:10.1016/j.ihj.2024.07.002.

Molecular genetics in 1991 arrhythmia probands and 2782 relatives in Norway: Results from 17 years of genetic testing in a national laboratory.

Stava TT, Berge KE, Haugaa KH, et al.

Clinical genetics 2024; (106(5)):585-602 doi:10.1111/cge.14593.

What an anesthesiologist should know about pediatric arrhythmias.

Kuntz MT, Eagle SS, Dalal A, et al.

Paediatric anaesthesia 2024; (34(12)):1187-1199 doi:10.1111/pan.14980.

Detection of distant relatedness in biobanks to identify undiagnosed cases of Mendelian disease as applied to Long QT syndrome.

Lancaster MC, Chen HH, Shoemaker MB, et al.

Nature communications 2024; (15(1)):7507 doi:10.1038/s41467-024-51977-4.

From genes to clinical management: A comprehensive review of long QT syndrome pathogenesis and treatment.

Zhu W, Bian X, Lv J

Heart rhythm O2 2024; (5(8)):573-586 doi:10.1016/j.hroo.2024.07.006.

The Yield of Genetic Testing and Putative Genetic Factors of Disease Heterogeneity in Long QT Syndrome Patients.

Bukaeva A, Ershova A, Kharlap M, et al.

International journal of molecular sciences 2024; (25(22)) doi:10.3390/ijms252211976.

Broad Electrocardiogram Syndromes Spectrum: From Common Emergencies to Particular Electrical Heart Disorders-Part II.

Ceasovschih A, Balta A, Șorodoc V, et al.

Diagnostics (Basel, Switzerland) 2025; (15(12)) doi:10.3390/diagnostics15121568.

Characteristics, clinical course, and cardiac events of patients with previously asymptomatic long QT syndrome.

Rudquist EV, Neves R, Bains S, et al.

Heart rhythm 2025; doi:10.1016/j.hrthm.2025.06.045.

Congenital Long QT Syndrome: A Focus on Risk Stratification and Management.

Ranganathan D, Grondin S, Hadjeres R, Joza J

Reviews in cardiovascular medicine 2025; (26(6)):36779 doi:10.31083/RCM36779.

Beyond the Beat, Next-Generation Sequencing Discovery of Novel RYR2 Gene Variant in Long QT Syndrome.

Kalayinia S, Jolfayi AG, Soheili A, et al.

Cardiology research and practice 2025; (2025()):1928541 doi:10.1155/crp/1928541.

Spectrum of genetic variants detected in children tested for long QT syndrome.

Kemezyte A, Meskiene R, Utkus A, Burnyte B

BMC cardiovascular disorders 2025; (25(1)):670 doi:10.1186/s12872-025-05118-4.

Inhibition of Satellite Glial Cell Activation in Stellate Ganglia Prevents Ventricular Arrhythmogenesis and Remodeling After Myocardial Infarction.

Zhou Z, Zhang H, Xiong H, et al.

Circulation. Arrhythmia and electrophysiology 2025; (18(10)):e013866 doi:10.1161/CIRCEP.125.013866.

Optimizing Peri-Operative Pain Management in Children With Long QT Syndrome and Catecholaminergic Polymorphic Ventricular Tachycardia Undergoing Left Cardiac Sympathetic Denervation: A Case Series on Continuous Erector Spinae Plane Block and Serratus Plane Block.

Mossetti V, Di Corrado R, HaxhiNasto H, et al.

Paediatric anaesthesia 2026; (36(2)):173-180 doi:10.1111/pan.70075.

Different beta-blockers for preventing arrhythmic events in patients with long QT syndrome: a network meta-analysis.

Jiang Y, Zhang L, Xiong H, et al.

Frontiers in medicine 2025; (12()):1730755 doi:10.3389/fmed.2025.1730755.

Case Report Series: Genetic and clinical characterization of long QT syndrome in admixed Ecuadorian patients and its implications for sudden cardiac death risk.

Paz-Cruz E, Ruiz-Pozo VA, Cadena-Ullauri S, et al.

Frontiers in cardiovascular medicine 2026; (13()):1680300 doi:10.3389/fcvm.2026.1680300.