Research & Literature

Corneal Neuralgia after LASIK.

Theophanous C, Jacobs DS, Hamrah P

Optometry and vision science : official publication of the American Academy of Optometry 2015; (92(9)):e233-40 doi:10.1097/OPX.0000000000000652.

The association between sleep duration and dry eye syndrome among Korean adults.

Lee W, Lim SS, Won JU, et al.

Sleep medicine 2015; (16(11)):1327-1331 doi:10.1016/j.sleep.2015.06.021.

Scope of practice of optometrists working in the UK Hospital Eye Service: a national survey.

Harper R, Creer R, Jackson J, et al.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) 2016; (36(2)):197-206 doi:10.1111/opo.12262.

Tear film osmolarity and dry eye disease: a review of the literature.

Potvin R, Makari S, Rapuano CJ

Clinical ophthalmology (Auckland, N.Z.) 2015; (9()):2039-47 doi:10.2147/OPTH.S95242.

Hyperosmolar Tears Induce Functional and Structural Alterations of Corneal Nerves: Electrophysiological and Anatomical Evidence Toward Neurotoxicity.

Hirata H, Mizerska K, Marfurt CF, Rosenblatt MI

Investigative ophthalmology & visual science 2015; (56(13)):8125-40 doi:10.1167/iovs.15-18383.

In pursuit of objective dry eye screening clinical techniques.

Kanellopoulos AJ, Asimellis G

Eye and vision (London, England) 2016; (3()):1 doi:10.1186/s40662-015-0032-4.

Burning Eye Syndrome: Do Neuropathic Pain Mechanisms Underlie Chronic Dry Eye?

Kalangara JP, Galor A, Levitt RC, et al.

Pain medicine (Malden, Mass.) 2016; (17(4)):746-55 doi:10.1093/pm/pnv070.

Corneal Mechanical Thresholds Negatively Associate With Dry Eye and Ocular Pain Symptoms.

Spierer O, Felix ER, McClellan AL, et al.

Investigative ophthalmology & visual science 2016; (57(2)):617-25 doi:10.1167/iovs.15-18133.

Predictors of Discordance between Symptoms and Signs in Dry Eye Disease.

Vehof J, Sillevis Smitt-Kamminga N, Nibourg SA, Hammond CJ

Ophthalmology 2017; (124(3)):280-286 doi:10.1016/j.ophtha.2016.11.008.

Effects of the External Environment on Dry Eye Disease.

Calonge M, Pinto-Fraga J, González-García MJ, et al.

International ophthalmology clinics 2017; (57(2)):23-40 doi:10.1097/IIO.0000000000000168.

Prospective evaluation of intense pulsed light and meibomian gland expression efficacy on relieving signs and symptoms of dry eye disease due to meibomian gland dysfunction.

Dell SJ, Gaster RN, Barbarino SC, Cunningham DN

Clinical ophthalmology (Auckland, N.Z.) 2017; (11()):817-827 doi:10.2147/OPTH.S130706.

TFOS DEWS II Definition and Classification Report.

Craig JP, Nichols KK, Akpek EK, et al.

The ocular surface 2017; (15(3)):276-283 doi:10.1016/j.jtos.2017.05.008.

TFOS DEWS II pain and sensation report.

Belmonte C, Nichols JJ, Cox SM, et al.

The ocular surface 2017; (15(3)):404-437 doi:10.1016/j.jtos.2017.05.002.

TFOS DEWS II pathophysiology report.

Bron AJ, de Paiva CS, Chauhan SK, et al.

The ocular surface 2017; (15(3)):438-510 doi:10.1016/j.jtos.2017.05.011.

TFOS DEWS II iatrogenic report.

Gomes JAP, Azar DT, Baudouin C, et al.

The ocular surface 2017; (15(3)):511-538 doi:10.1016/j.jtos.2017.05.004.

TFOS DEWS II Diagnostic Methodology report.

Wolffsohn JS, Arita R, Chalmers R, et al.

The ocular surface 2017; (15(3)):539-574 doi:10.1016/j.jtos.2017.05.001.

TFOS DEWS II Report Executive Summary.

Craig JP, Nelson JD, Azar DT, et al.

The ocular surface 2017; (15(4)):802-812 doi:10.1016/j.jtos.2017.08.003.

Dry Eye Disease: Prevalence, Assessment, and Management.

Rouen PA, White ML

Home healthcare now 2018; (36(2)):74-83 doi:10.1097/NHH.0000000000000652.

Variability of Tear Osmolarity Measurements With a Point-of-Care System in Healthy Subjects-Systematic Review.

Baenninger PB, Voegeli S, Bachmann LM, et al.

Cornea 2018; (37(7)):938-945 doi:10.1097/ICO.0000000000001562.

Ocular allergy as a risk factor for dry eye in adults and children.

Villani E, Rabbiolo G, Nucci P

Current opinion in allergy and clinical immunology 2018; (18(5)):398-403 doi:10.1097/ACI.0000000000000471.

Clinical subtypes of dry eye in youthful clinical sample in Ghana.

Asiedu K, Dzasimatu SK, Kyei S

Contact lens & anterior eye : the journal of the British Contact Lens Association 2019; (42(2)):206-211 doi:10.1016/j.clae.2018.10.005.

Definition and Diagnostic Criteria of Dry Eye Disease: Historical Overview and Future Directions.

Shimazaki J

Investigative ophthalmology & visual science 2018; (59(14)):DES7-DES12 doi:10.1167/iovs.17-23475.

Sleep Disorders are a Prevalent and Serious Comorbidity in Dry Eye.

Ayaki M, Tsubota K, Kawashima M, et al.

Investigative ophthalmology & visual science 2018; (59(14)):DES143-DES150 doi:10.1167/iovs.17-23467.

Intense pulsed light therapy: A promising complementary treatment for dry eye disease.

Mejía LF, Gil JC, Jaramillo M

Archivos de la Sociedad Espanola de Oftalmologia 2019; (94(7)):331-336 doi:10.1016/j.oftal.2019.03.009.

Relationship between dry eye and glycosylated haemoglobin among diabetics in Ibadan, Nigeria.

Olaniyan SI, Fasina O, Bekibele CO, Ogundipe AO

The Pan African medical journal 2019; (33()):14 doi:10.11604/pamj.2019.33.14.14074.

The use of preservatives in dry eye drops.

Walsh K, Jones L

Clinical ophthalmology (Auckland, N.Z.) 2019; (13()):1409-1425 doi:10.2147/OPTH.S211611.

Analysis of tear inflammatory molecules and clinical correlations in evaporative dry eye disease caused by meibomian gland dysfunction.

Wu X, Chen X, Ma Y, et al.

International ophthalmology 2020; (40(11)):3049-3058 doi:10.1007/s10792-020-01489-z.

Nocturnal Lagophthalmos and Sleep Quality in Patients with Dry Eye Disease.

Takahashi A, Negishi K, Ayaki M, et al.

Life (Basel, Switzerland) 2020; (10(7)) doi:10.3390/life10070105.

A Review of Dry Eye Questionnaires: Measuring Patient-Reported Outcomes and Health-Related Quality of Life.

Okumura Y, Inomata T, Iwata N, et al.

Diagnostics (Basel, Switzerland) 2020; (10(8)) doi:10.3390/diagnostics10080559.

Investigating the Role of Optometrists in Teleophthalmology and the Implications of Increasing Access to Advanced Imaging Techniques and Digital Referral: A Systematic Search and Review.

Conway MP, Forristal MT, Treacy MP, Duignan ES

Telemedicine journal and e-health : the official journal of the American Telemedicine Association 2021; (27(9)):974-981 doi:10.1089/tmj.2020.0284.

Developing evidence-based guidance for the treatment of dry eye disease with artificial tear supplements: A six-month multicentre, double-masked randomised controlled trial.

Craig JP, Muntz A, Wang MTM, et al.

The ocular surface 2021; (20()):62-69 doi:10.1016/j.jtos.2020.12.006.

Distribution and Predictors of Initial Glaucoma Care Among Ophthalmologists and Optometrists: A Population-based Study.

Quinn MP, Johnson D, Whitehead M, et al.

Journal of glaucoma 2021; (30(6)):e300-e304 doi:10.1097/IJG.0000000000001792.

Modifiable lifestyle risk factors for dry eye disease.

Wang MTM, Muntz A, Mamidi B, et al.

Contact lens & anterior eye : the journal of the British Contact Lens Association 2021; (44(6)):101409 doi:10.1016/j.clae.2021.01.004.

Could contact lens dryness discomfort symptoms sometimes have a neuropathic basis?

McMonnies CW

Eye and vision (London, England) 2021; (8(1)):12 doi:10.1186/s40662-021-00236-4.

The physical and mental burden of dry eye disease: A large population-based study investigating the relationship with health-related quality of life and its determinants.

Morthen MK, Magno MS, Utheim TP, et al.

The ocular surface 2021; (21()):107-117 doi:10.1016/j.jtos.2021.05.006.

DRY EYE DISEASE. A REVIEW.

Zemanová M

Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti 2021; (77(3)):107–119 doi:10.31348/2020/29.

Etiology of Epiphora.

Lee JM, Baek JS

Korean journal of ophthalmology : KJO 2021; (35(5)):349-354 doi:10.3341/kjo.2021.0069.

A Water-free 0.1% Cyclosporine A Solution for Treatment of Dry Eye Disease: Results of the Randomized Phase 2B/3 ESSENCE Study.

Sheppard JD, Wirta DL, McLaurin E, et al.

Cornea 2021; (40(10)):1290-1297 doi:10.1097/ICO.0000000000002633.

The Relationship Between Dry Eye Disease and Digital Screen Use.

Al-Mohtaseb Z, Schachter S, Shen Lee B, et al.

Clinical ophthalmology (Auckland, N.Z.) 2021; (15()):3811-3820 doi:10.2147/OPTH.S321591.

Efficacy of topical cyclosporine 0.05% and osmoprotective lubricating eye drops in treating dry eye disease and inflammation.

Mullick R, Annavajjhala S, Thakur P, et al.

Indian journal of ophthalmology 2021; (69(12)):3473-3477 doi:10.4103/ijo.IJO_3822_20.

Dry eye disease and psychiatric disorders: A systematic review and meta-analysis.

Basilious A, Xu CY, Malvankar-Mehta MS

European journal of ophthalmology 2022; (32(4)):1872-1889 doi:10.1177/11206721211060963.

Recharacterization of superior limbic keratoconjunctivitis via a subdividing grading method in 236 Chinese patients.

Cheng C, Zhu M, Lin T, et al.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2022; (260(7)):2291-2298 doi:10.1007/s00417-022-05575-z.

Characterization of meibomian gland dysfunction in patients with rosacea.

Barbosa EB, Tavares CM, Silva DFLD, et al.

Arquivos brasileiros de oftalmologia 2023; (86(4)):365-371 doi:10.5935/0004-2749.20230043.

The Correlation between Matrix Metalloproteinase-9 Point-of-Care Immunoassay, Tear Film Osmolarity, and Ocular Surface Parameters.

Kang MJ, Kim HS, Kim MS, Kim EC

Journal of ophthalmology 2022; (2022()):6132016 doi:10.1155/2022/6132016.

Lacrimal gland regeneration: The unmet challenges and promise for dry eye therapy.

Veernala I, Jaffet J, Fried J, et al.

The ocular surface 2022; (25()):129-141 doi:10.1016/j.jtos.2022.06.005.

Reliability, validity, and responsiveness of the Thai version of the Dry Eye-Related Quality-of-Life Score questionnaire.

Tananuvat N, Tansanguan S, Wongpakaran N, Wongpakaran T

PloS one 2022; (17(7)):e0271228 doi:10.1371/journal.pone.0271228.

Patient and Provider Experience in Real-Time Telemedicine Consultations for Pediatric Ophthalmology.

Stewart C, Coffey-Sandoval J, Souverein EA, et al.

Clinical ophthalmology (Auckland, N.Z.) 2022; (16()):2943-2953 doi:10.2147/OPTH.S374811.

Prevalence and Incidence of Dry Eye and Meibomian Gland Dysfunction in the United States: A Systematic Review and Meta-analysis.

McCann P, Abraham AG, Mukhopadhyay A, et al.

JAMA ophthalmology 2022; (140(12)):1181-1192 doi:10.1001/jamaophthalmol.2022.4394.

Prevalence and characteristics of dry eye disease in Parkinson's disease: a systematic review and meta-analysis.

Nagino K, Sung J, Oyama G, et al.

Scientific reports 2022; (12(1)):18348 doi:10.1038/s41598-022-22037-y.

Association between dry eye disease and depression: An umbrella review.

Tsai CY, Jiesisibieke ZL, Tung TH

Frontiers in public health 2022; (10()):910608 doi:10.3389/fpubh.2022.910608.

Dry eye disease: identification and therapeutic strategies for primary care clinicians and clinical specialists.

Sheppard J, Shen Lee B, Periman LM

Annals of medicine 2023; (55(1)):241-252 doi:10.1080/07853890.2022.2157477.

Ion channels in dry eye disease.

Ashok N, Khamar P, D'Souza S, et al.

Indian journal of ophthalmology 2023; (71(4)):1215-1226 doi:10.4103/IJO.IJO_3020_22.

Efficacy of artificial tears containing trehalose and hyaluronic acid for dry eye disease in women aged 42-54 versus ≥ 55 years.

Mateo-Orobia AJ, Del Prado Sanz E, Blasco-Martínez A, et al.

Contact lens & anterior eye : the journal of the British Contact Lens Association 2023; (46(4)):101845 doi:10.1016/j.clae.2023.101845.

Diagnosing dry-eye: Which tests are most accurate?

Papas EB

Contact lens & anterior eye : the journal of the British Contact Lens Association 2023; (46(5)):102048 doi:10.1016/j.clae.2023.102048.

Safety and efficacy of cyclosporine (0.05% versus 0.09%) in dry eye disease. Is it the strength of cyclosporin that really matters?

Rajpoot M, Singh D, Pandey K, Bhargava R

Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH 2022; (14(28)):64-77 doi:10.3126/nepjoph.v14i2.38928.

Cross-sectional Study Exploring Vision-related Quality of Life in Dry Eye Disease in a Norwegian Optometric Practice.

Erøy ÅA, Utheim TP, Sundling V

Optometry and vision science : official publication of the American Academy of Optometry 2023; (100(10)):679-687 doi:10.1097/OPX.0000000000002058.

Efficacy and safety of intense pulsed light delivered by the C.STIM® for treatment of Meibomian gland dysfunction.

Auger R, Trone MC, Chhuy E, et al.

Journal francais d'ophtalmologie 2024; (47(5)):104016 doi:10.1016/j.jfo.2023.09.015.

The Importance of Preventing and Managing Tear Dysfunction Syndrome in Allergic Conjunctivitis and How to Tackle This Problem.

Montero-Iruzubieta J, Sanchez Hernandez MC, Dávila I, Leceta A

Journal of investigational allergology & clinical immunology 2023; (33(6)):439-445 doi:10.18176/jiaci.0960.

Efficacy of topical 0.05% cyclosporine A and 0.1% sodium hyaluronate in post-refractive surgery chronic dry eye patients with ocular pain.

Zhao L, Chen J, Duan H, et al.

BMC ophthalmology 2024; (24(1)):28 doi:10.1186/s12886-024-03294-z.

Is there a relationship between the severity of disease in major depressive disorder patients and dry eye disease?

Gökçe GD, Metin M

International ophthalmology 2024; (44(1)):163 doi:10.1007/s10792-024-03050-8.

Topical glaucoma medications - Possible implications on the meibomian glands.

Fineide F, Magnø M, Dahlø K, et al.

Acta ophthalmologica 2024; (102(7)):735-748 doi:10.1111/aos.16728.

Vectored Thermal Pulsation as a Treatment for Meibomian Gland Dysfunction: A Review Spanning 15 Years.

Blackie CA, Murakami D, Donnenfeld E, Oliff HS

Ophthalmology and therapy 2024; (13(8)):2083-2123 doi:10.1007/s40123-024-00976-1.

Dry eye disease adverse reaction of pharmacological treatment for early-stage breast cancer.

He J, Zhou Y, Xiu M, et al.

The ocular surface 2024; (34()):124-131 doi:10.1016/j.jtos.2024.07.005.

Effects of social support on vision-related quality of life in older adults with dry eye disease: the chain mediating role of illness perception and coping style.

Pan H, Pan X, Gu D, Wang X

Frontiers in psychology 2024; (15()):1411661 doi:10.3389/fpsyg.2024.1411661.

Environmental and Occupational Triggers of Dry Eye Symptoms in the Ahsa Region of Saudi Arabia: A Cross-Sectional Study.

Al-Dossary SK

Clinical ophthalmology (Auckland, N.Z.) 2024; (18()):2427-2438 doi:10.2147/OPTH.S474832.

Navigating Dry Eye Research: A Comprehensive Review of Etiology, Clinical Trials, Patents, and Recent Advancements.

Pal V, Verma S

Reviews on recent clinical trials 2025; (20(3)):199-210 doi:10.2174/0115748871310261240929163138.

Clinical practice patterns in the management of dry eye disease: A TFOS international survey 2023-24.

Wolffsohn JS, Semp DA, Dutta D, et al.

The ocular surface 2025; (36()):164-172 doi:10.1016/j.jtos.2024.12.008.

Efficacy of moisture chamber goggles combined with fluorometholone eye drops on visual function and oxidative stress in patients with dry eye disease.

Zhou J, Sun Y, Cheng Y, et al.

American journal of translational research 2024; (16(12)):7782-7791 doi:10.62347/PUNY8378.

Relative importance of tear homeostatic signs for the diagnosis of dry eye disease.

Wolffsohn JS, Travé-Huarte S, Stapleton F, et al.

The ocular surface 2025; (36()):151-155 doi:10.1016/j.jtos.2025.01.010.

The impact of dry eye disease on patient-reported quality of life: A Save Sight Dry Eye Registry study.

Kandel H, Stapleton F, Downie LE, et al.

The ocular surface 2025; (37()):11-23 doi:10.1016/j.jtos.2025.02.005.

Excessive screen time exposure leads to dry eyes and inflammatory conjunctivitis in children.

Shah M, Natarajan SB, Ahmad N

Irish journal of medical science 2025; (194(2)):597-602 doi:10.1007/s11845-025-03920-9.

[Pharmacological correction of burning eye syndrome].

Safonova TN, Medvedeva ES

Vestnik oftalmologii 2025; (141(2)):51-58 doi:10.17116/oftalma202514102151.

TFOS DEWS III: Diagnostic Methodology.

Wolffsohn JS, Benítez-Del-Castillo JM, Loya-Garcia D, et al.

American journal of ophthalmology 2025; (279()):387-450 doi:10.1016/j.ajo.2025.05.033.

Comparison of patient reported dry eye symptoms as evaluated by the ocular surface disease index and symptom assessment.

Mathebula SD, Khosa PR, Maleswene MM

African journal of primary health care & family medicine 2025; (17(1)):e1-e7 doi:10.4102/phcfm.v17i1.4861.

TFOS DEWS III: Management and Therapy.

Jones L, Craig JP, Markoulli M, et al.

American journal of ophthalmology 2025; (279()):289-386 doi:10.1016/j.ajo.2025.05.039.

TFOS DEWS III: Digest.

Stapleton F, Argüeso P, Asbell P, et al.

American journal of ophthalmology 2025; (279()):451-553 doi:10.1016/j.ajo.2025.05.040.

Prevalence of dry eye disease and its association with sleep quality and depression: a hospital-based survey in Thai population.

Jongkhajornpong P, Lekhanont K, Anothaisintawee T, et al.

BMJ open 2025; (15(6)):e094046 doi:10.1136/bmjopen-2024-094046.

Characterizing inflammatory, nerve innervation, and immune alterations in three dry eye disease animal models.

Wu Y, Ye H, Zhang H, et al.

Experimental eye research 2025; (260()):110580 doi:10.1016/j.exer.2025.110580.

Influence of baseline characteristics on subjective improvement of dry eye after intense pulsed light therapy.

Carrillo-Pulido M, Ortiz-Peregrina S, López Pérez MD, et al.

Contact lens & anterior eye : the journal of the British Contact Lens Association 2026; (49(1)):102514 doi:10.1016/j.clae.2025.102514.

Changes in human tear metabolome following topical 0.05% cyclosporine A on primary Sjögren's syndrome.

Li Y, Huang M, Xie L, et al.

Frontiers in medicine 2025; (12()):1653585 doi:10.3389/fmed.2025.1653585.

Long-Term Efficacy and Safety of 0.1% Cyclosporine A Cationic Emulsion in Advanced Dry Eye Disease: A 24-Month Retrospective Study.

Sarnat-Kucharczyk M, Nowak M, Mrukwa-Kominek E

Pharmaceuticals (Basel, Switzerland) 2025; (18(11)) doi:10.3390/ph18111682.

Corneal Amiodarone Deposition and Its Implications for Autologous Serum Eye Drop Therapy: A Case Report.

Saigal K, Sussmane S, Tuli S

Cureus 2025; (17(11)):e96670 doi:10.7759/cureus.96670.

Association between sleep quality and corneal microstructural alterations in patients with dry eye disease: An in vivo confocal microscopy study.

Li Y, Zhu D, Ding N

Photodiagnosis and photodynamic therapy 2026; (59()):105496 doi:10.1016/j.pdpdt.2026.105496.