Research & Literature

The international, prospective Glanzmann Thrombasthenia Registry: treatment and outcomes in surgical intervention.

Poon MC, d'Oiron R, Zotz RB, et al.

Haematologica 2015; (100(8)):1038-44 doi:10.3324/haematol.2014.121384.

The international, prospective Glanzmann Thrombasthenia Registry: treatment modalities and outcomes of non-surgical bleeding episodes in patients with Glanzmann thrombasthenia.

Di Minno G, Zotz RB, d'Oiron R, et al.

Haematologica 2015; (100(8)):1031-7 doi:10.3324/haematol.2014.121475.

Stem Cell Transplant in Severe Glanzmann Thrombasthenia in an Adult Patient.

Ramzi M, Dehghani M, Haghighat S, Nejad HH

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 2016; (14(6)):688-690 doi:10.6002/ect.2014.0165.

Effects Of Glycoprotein IIb/IIIa Antagonists: Anti Platelet Aggregation And Beyond.

Giordano A, Musumeci G, D'Angelillo A, et al.

Current drug metabolism 2016; (17(2)):194-203 doi:10.2174/1389200217666151211121112.

New Insights Into the Treatment of Glanzmann Thrombasthenia.

Poon MC, Di Minno G, d'Oiron R, Zotz R

Transfusion medicine reviews 2016; (30(2)):92-9.

Successful management of perioperative hemostasis in a patient with Glanzmann thrombasthenia who underwent a right total mastectomy.

Ogawa Y, Kunishima S, Yanagisawa K, et al.

International journal of hematology 2017; (105(2)):221-225 doi:10.1007/s12185-016-2096-x.

Glanzmann thrombasthenia in pregnancy: Optimising maternal and fetal outcomes.

Wijemanne A, Watt-Coote I, Austin S

Obstetric medicine 2016; (9(4)):169-170 doi:10.1177/1753495X16655021.

Alterations of the platelet proteome in type I Glanzmann thrombasthenia caused by different homozygous delG frameshift mutations in ITGA2B.

Loroch S, Trabold K, Gambaryan S, et al.

Thrombosis and haemostasis 2017; (117(3)):556-569 doi:10.1160/TH16-07-0515.

Oral Surgery in Patients With Glanzmann Thrombasthenia: A Case Series.

Segna E, Artoni A, Sacco R, Giannì AB

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2017; (75(2)):256-259 doi:10.1016/j.joms.2016.09.048.

Novel mutations in Thai patients with glanzmann thrombasthenia.

Ittiwut R, Suchartlikitwong P, Kittikalayawong Y, et al.

European journal of haematology 2017; (99(6)):520-524 doi:10.1111/ejh.12965.

Evaluation of platelet surface glycoproteins in patients with Glanzmann thrombasthenia: Association with bleeding symptoms.

Mutreja D, Sharma RK, Purohit A, et al.

The Indian journal of medical research 2017; (145(5)):629-634 doi:10.4103/ijmr.IJMR_718_14.

Assessment of platelet function on the routine coagulation analyzer Sysmex CS-2000i.

Frère C, Kobayashi K, Dunois C, et al.

Platelets 2018; (29(1)):95-97 doi:10.1080/09537104.2017.1353683.

Anti-αIIb β3 immunization in Glanzmann thrombasthenia: review of literature and treatment recommendations.

Fiore M, d'Oiron R, Pillois X, Alessi MC

British journal of haematology 2018; (181(2)):173-182 doi:10.1111/bjh.15087.

Using flow cytometry to monitor glycoprotein IIb-IIIa activation.

Frelinger AL

Platelets 2018; (29(7)):670-676 doi:10.1080/09537104.2018.1478073.

How we treat the platelet glycoprotein defects; Glanzmann thrombasthenia and Bernard Soulier syndrome in children and adults.

Grainger JD, Thachil J, Will AM

British journal of haematology 2018; (182(5)):621-632 doi:10.1111/bjh.15409.

From thrombasthenia to next generation thrombocytopenia: Neonatal alloimmune thrombocytopenia induced by maternal Glanzmann thrombasthenia.

Barg AA, Hauschner H, Luboshitz J, et al.

Pediatric blood & cancer 2018; (65(12)):e27376 doi:10.1002/pbc.27376.

Molecular genetic diagnosis of Tunisian Glanzmann thrombasthenia patients reveals a common nonsense mutation in the ITGA2B gene that seems to be specific for the studied population.

Aloui C, Chakroun T, Granados V, et al.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2018; (29(8)):689-696 doi:10.1097/MBC.0000000000000779.

Missed at first Glanz: Glanzmann thrombasthenia initially misdiagnosed as Von Willebrand Disease.

Doherty D, Singleton E, Byrne M, et al.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2019; (58(1)):58-60 doi:10.1016/j.transci.2018.11.008.

Low Concentrations of Recombinant Factor VIIa May Improve the Impaired Thrombin Generation of Glanzmann Thrombasthenia Patients.

Levy-Mendelovich S, Levy T, Budnik I, et al.

Thrombosis and haemostasis 2019; (119(1)):117-127 doi:10.1055/s-0038-1676348.

Anesthetic experience for orthopedic surgery on a patient with Glanzmann's thrombasthenia refractory to platelet transfusion: A case report.

Park JB, Shin YS, Kim SH

Korean journal of anesthesiology 2009; (57(4)):507-510 doi:10.4097/kjae.2009.57.4.507.

Severe Intestinal Bleeding in a Woman with Glanzmann Thrombasthenia.

Mesquita R, Santos I, Monteiro H

European journal of case reports in internal medicine 2018; (5(2)):000796 doi:10.12890/2017_000796.

Glanzmann Thrombasthenia in Children: Experience From a Tertiary Care Center in Southern India.

Kongalappa S, Reddy JM, Durugappa T, et al.

Journal of pediatric hematology/oncology 2019; (41(2)):e68-e71 doi:10.1097/MPH.0000000000001367.

Acquired Glanzmann thrombasthenia: From antibodies to anti-platelet drugs.

Nurden AT

Blood reviews 2019; (36()):10-22 doi:10.1016/j.blre.2019.03.004.

Identification of one novel pathogenic ITGB3 mutation and two known mutations in two Chinese pedigrees with hereditary Glanzmann thrombasthenia.

Lu Z, Nikuze L, Zhong Z, et al.

Platelets 2020; (31(3)):355-359 doi:10.1080/09537104.2019.1615614.

Glanzmann thrombasthenia: genetic basis and clinical correlates.

Botero JP, Lee K, Branchford BR, et al.

Haematologica 2020; (105(4)):888-894 doi:10.3324/haematol.2018.214239.

Two homozygous missense mutations in ITGB3 gene as a cause of Glanzmann Thrombasthenia in four consanguineous Pakistani pedigrees.

Ali T, Gul S, Amar A, et al.

International journal of laboratory hematology 2020; (42(5)):628-635 doi:10.1111/ijlh.13266.

Bleeding phenotype and diagnostic characterization of patients with congenital platelet defects.

Blaauwgeers MW, Kruip MJHA, Beckers EAM, et al.

American journal of hematology 2020; (95(10)):1142-1147 doi:10.1002/ajh.25910.

Management of Refractory Menstrual Bleeding in an Adolescent with Glanzmann Thrombasthenia: A Case Report and Review.

King LJ, Huff J, Heber D, et al.

Case reports in obstetrics and gynecology 2020; (2020()):8848763 doi:10.1155/2020/8848763.

Glanzmann's thrombasthenia: a rare bleeding disorder in a Nigerian girl.

Ezenwosu OU, Chukwu BF, Uwaezuoke NA, et al.

African health sciences 2020; (20(2)):753-757 doi:10.4314/ahs.v20i2.27.

Use of rFVIIa in Preventing Recurrent Intra-articular Hemorrhages in a 15-Year-Old Patient With Glanzmann Thrombasthenia.

Laguna P

Journal of pediatric hematology/oncology 2021; (43(8)):e1120-e1123 doi:10.1097/MPH.0000000000002105.

Mutations in RASGRP2 gene identified in patients misdiagnosed as Glanzmann thrombasthenia patients.

Rosenberg N, Dardik R, Hauschner H, et al.

Blood cells, molecules & diseases 2021; (89()):102560 doi:10.1016/j.bcmd.2021.102560.

Flow cytometric analysis of platelet surface glycoproteins in the diagnosis of thirty-two Turkish patients with Glanzmann thrombasthenia: a multicenter experience

Saraymen B, Muhtaroğlu S, Köker MY, et al.

Turkish journal of medical sciences 2021; (51(4)):2135-2141 doi:10.3906/sag-2006-107.

Glanzmann Thrombasthenia: Perspectives from Clinical Practice on Accurate Diagnosis and Optimal Treatment Strategies.

Mathews N, Rivard GE, Bonnefoy A

Journal of blood medicine 2021; (12()):449-463 doi:10.2147/JBM.S271744.

Glanzmann Thrombasthenia: Use of the Soft Splint with Tranexamic Acid Paste to Reduce Spontaneous Oral Bleeding.

Bhavyaa R, Vignesh KC, Muthu MS, et al.

International journal of clinical pediatric dentistry 2021; (14(4)):580-585 doi:10.5005/jp-journals-10005-1973.

Blood management strategies in congenital Glanzmann thrombasthenia at a hematology referral center.

Kasinathan G, Sathar J

Blood research 2021; (56(4)):315-321 doi:10.5045/br.2021.2021165.

Elevated CD9 expression as a potential biomarker for diagnosis of Bernard-Soulier syndrome.

Sharifi MJ, Vakili E, Ilkhanipoor H, et al.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2022; (33(3)):159-161 doi:10.1097/MBC.0000000000001117.

Excellent Outcome Following Sibling Peripheral Blood Hematopoietic Stem Cell Transplantation for Glanzmann Thrombasthenia: A Case Report.

Li JH, Sun SW, Ai Y, et al.

Frontiers in pediatrics 2021; (9()):776927 doi:10.3389/fped.2021.776927.

Stability and utility of flow cytometric platelet activation tests: A modality to bridge the gap between diagnostic demand and supply.

Dave RG, Geevar T, Chellaiya GK, et al.

Platelets 2022; (33(7)):1043-1051 doi:10.1080/09537104.2022.2042232.

How I manage pregnancy in women with Glanzmann thrombasthenia.

Fiore M, Sentilhes L, d'Oiron R

Blood 2022; (139(17)):2632-2641 doi:10.1182/blood.2021011595.

Utility of the ISTH bleeding assessment tool (BAT) in diagnosis of Glanzmann Thrombasthenia patients.

Saqlain N, Fateen T, Tufail H, Mazher N

Pakistan journal of medical sciences 2022; (38(4Part-II)):791-795 doi:10.12669/pjms.38.4.5361.

Platelet abnormalities in patients with Parkinson's disease undergoing preoperative evaluation for deep brain stimulation.

Chou SC, Tai CH, Tseng SH

Scientific reports 2022; (12(1)):14625 doi:10.1038/s41598-022-18992-1.

High Rates of Anti-αIIbβ3 Antibodies Produced by a Glanzmann Thrombasthenia Patient after First and Unique Red Blood Cells Administration.

Huguenin Y, Levoir L, Bouton M, Fiore M

Acta haematologica 2023; (146(1)):44-46 doi:10.1159/000526224.

Glanzmann Thrombasthenia in Pakistani Patients: Identification of 7 Novel Pathogenic Variants in the Fibrinogen Receptor αIIbβ3.

Siddiqi MYJ, Boeckelmann D, Naz A, et al.

Cells 2023; (12(2)) doi:10.3390/cells12020213.

Novel homozygous silent mutation of ITGB3 gene caused Glanzmann thrombasthenia.

Wang Z, Xu Y, Sun Y, et al.

Frontiers in pediatrics 2022; (10()):1062900 doi:10.3389/fped.2022.1062900.

Emergency management of patients with Glanzmann thrombasthenia: consensus recommendations from the French reference center for inherited platelet disorders.

Fiore M, Giraudet JS, Alessi MC, et al.

Orphanet journal of rare diseases 2023; (18(1)):171 doi:10.1186/s13023-023-02787-2.

Hemorrhage of Upper Digestive and Respiratory Tracts in a Child with Glanzmann Thrombasthenia.

Michali M, Basiari L, Komnos I, et al.

Maedica 2023; (18(2)):363-367 doi:10.26574/maedica.2023.18.2.363.

Myricetin as a promising inhibitor of platelet fibrinogen receptor in humans.

Chang Y, Hsia CW, Huang WC, et al.

Heliyon 2023; (9(10)):e20286 doi:10.1016/j.heliyon.2023.e20286.

Thrombocytopenia and hyperthyroidism: A case report and literature review.

Yingchoncharoen P, Abdelnabi M, Thongpiya J, et al.

Clinical case reports 2023; (11(10)):e7960 doi:10.1002/ccr3.7960.

Glanzmann Thrombasthenia Associated with Siderotic Synovitis and Arthropathy: A Case Report.

Alawad MJ, Abu-Tineh M, Alshurafa A, et al.

Journal of blood medicine 2023; (14()):563-567 doi:10.2147/JBM.S418937.

Multidisciplinary management of a pregnancy complicated by Glanzmann thrombasthenia: A case report.

Hernandez MM, Buckley A, Mills A, et al.

Transfusion 2023; (63(12)):2384-2391 doi:10.1111/trf.17594.

Double jeopardy, glomangiopericytoma and Glanzmann thrombasthenia resulting in recurrent epistaxis: a case report.

Hammami E, Fath L, Debry C, Desprez D

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2024; (35(2)):62-65 doi:10.1097/MBC.0000000000001272.

Patient with a history of Glanzmann thrombasthenia presented with chronic subdural hematoma: a case report study.

Hasanpour M, Mehdizadeh H

Oxford medical case reports 2024; (2024(2)):omae004 doi:10.1093/omcr/omae004.

Fibrin glue in managing intractable gingival bleeding in patients with inherited bleeding disorders-a quasi-experimental pilot study.

Hussain S, Ali Zaidi SA, Sawani S, Moiz B

JPMA. The Journal of the Pakistan Medical Association 2024; (74(2)):378-383 doi:10.47391/JPMA.9378.

Catheter Intervention in a Patient with Intracranial Aneurysms and Glanzmann Thrombasthenia Caused by a Novel Homozygous Likely Pathogenic Variant in the ITGA2B Gene.

Boeckelmann D, von Dobeneck L, Henkes H, et al.

Diseases (Basel, Switzerland) 2024; (12(7)) doi:10.3390/diseases12070136.

Dental Management of Seven-Year-Old Child With Glanzmann Thrombasthenia: A Case Report.

Alduhayan G, Alsaif A, Almohareb R, Demyati M

Cureus 2024; (16(9)):e70243 doi:10.7759/cureus.70243.

Bleeding and quality of life in people with Glanzmann thrombasthenia-insights from the Glanzmann's 360 study.

Khair K, Fletcher S, Boyton M, Holland M

Research and practice in thrombosis and haemostasis 2024; (8(7)):102586 doi:10.1016/j.rpth.2024.102586.

Gastrointestinal Bleeding/Angiodysplasia in Patients With Glanzmann Thrombasthenia.

Tarawah RA, Tarawah AM

Journal of medical cases 2024; (15(12)):401-405 doi:10.14740/jmc4340.

Glanzmann Thrombasthenia in a Newborn Due to a Rare Homozygous Missense Mutation.

Faraz S, Nikhat F, Hayel Suleiman Beshtawi H, et al.

Cureus 2024; (16(12)):e75291 doi:10.7759/cureus.75291.

Obstetric and Gynaecological Challenges and Outcomes in Women and Girls With Glanzmann's Thrombasthenia.

Obeng-Tuudah D, Tarawah A, Ozkan M, Abdul-Kadir R

Haemophilia : the official journal of the World Federation of Hemophilia 2025; (31(3)):509-518 doi:10.1111/hae.70030.

Glanzmann's thrombasthenia in a twin pregnancy: A case report.

Xu VX, Brennecke SP

Case reports in women's health 2025; (46()):e00697 doi:10.1016/j.crwh.2025.e00697.

Novel homozygous frameshift mutation of ITGB3 in the Glanzmann thrombasthenia patient with abnormal bone metabolism and congenital bone defects.

Luo Y, Guo N, Wang Y, Li J

Orphanet journal of rare diseases 2025; (20(1)):189 doi:10.1186/s13023-025-03700-9.

Glanzmann thrombasthenia: a multi-center study of demographics, clinical spectrum, and treatment efficacy.

Sherief LM, El Ekiaby M, El-Hawy M, et al.

European journal of pediatrics 2025; (184(5)):318 doi:10.1007/s00431-025-06126-4.

Mixed Chimerism and Clinical Outcome of Hematopoietic Stem Cell Transplantation in Glanzmann Thrombasthenia: Experience on 2 Siblings and Literature Review.

Al-Antary ET, Chitlur M, Gadgeel M, Savaşan S

Journal of pediatric hematology/oncology 2025; (47(8)):429-435 doi:10.1097/MPH.0000000000003121.

European Management of Glanzmann's Thrombasthenia: A Survey of Current Clinical Practice.

Fiore M, Artoni A, Klamroth R, et al.

Haemophilia : the official journal of the World Federation of Hemophilia 2025; (31(6)):1261-1270 doi:10.1111/hae.70114.

Characterising Glanzmann Thrombasthenia in the United States: Real-World Data From the EPIC Cosmos Dataset.

Citla-Sridhar D, Liu D

Haemophilia : the official journal of the World Federation of Hemophilia 2025; doi:10.1111/hae.70170.

Management of Severe Menorrhagia in an Adolescent with Glanzmann Thrombasthenia: A Case Report and Treatment Approach.

Tiwari SK, Sonowal R, Bhowmick R, Joshi P

Journal of pediatric and adolescent gynecology 2025; doi:10.1016/j.jpag.2025.11.008.

Novel compound heterozygous ITGA2B mutations in Glanzmann thrombasthenia associated with adolescent osteoporosis.

Zhang Y, Luo Y, Zhang G

Platelets 2026; (37(1)):2612049 doi:10.1080/09537104.2025.2612049.