Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
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BGI Group (China)
Shenzhen, China
Mayo Clinic in Arizona
Scottsdale, United States
Broad Institute
Cambridge, United States
The University of Texas MD Anderson Cancer Center
Houston, United States
National Institutes of Health
Bethesda, United States
Azienda Ospedaliero-Universitaria Careggi
Florence, Italy
European Bioinformatics Institute
Cambridge, United Kingdom
Baylor College of Medicine
Houston, United States
Wellcome Sanger Institute
Cambridge, United Kingdom
Inserm
Paris, France
References
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Hemochromatosis, Erythrocytosis and the JAK2 p.V617F Mutation.
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Aquagenic cutaneous disorders.
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Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2017; (15(6)):602-608 doi:10.1111/ddg.13234.
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Re-evaluation of hematocrit as a determinant of thrombotic risk in erythrocytosis.
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Ruxolitinib: a targeted treatment option for patients with polycythemia vera.
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Cerebral intraparenchymal extramedullary hematopoiesis in polycythemia vera.
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Thrombotic Risk Detection in Patients with Polycythemia Vera: The Predictive Role of DNMT3A/TET2/ASXL1 Mutations.
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Case of aquagenic urticaria: Case report and the results of histopathological examination.
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The Journal of dermatology 2021; (48(1)):88-91 doi:10.1111/1346-8138.15615.
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Macroscopic Hematuria as the Initial Presentation of Polycythemia Vera.
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Cureus 2020; (12(10)):e10800 doi:10.7759/cureus.10800.
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Erythromelalgia Caused by Polycythemia Vera Combined with Primary Aldosteronism.
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Polycythemia Vera (PV): Update on Emerging Treatment Options.
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Polycythemia vera as a rare cause of hypertension in a young man.
Vetluzhskaya M, Abramova A, Oganesyan K, Podzolkov V
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Real-World Dosing Patterns of Ruxolitinib in Patients With Polycythemia Vera Who Are Resistant to or Intolerant of Hydroxyurea.
Altomare I, Parasuraman S, Paranagama D, et al.
Clinical lymphoma, myeloma & leukemia 2021; (21(11)):e915-e921 doi:10.1016/j.clml.2021.06.023.
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Data-driven analysis of the kinetics of the JAK2V617F allele burden and blood cell counts during hydroxyurea treatment of patients with polycythemia vera, essential thrombocythemia, and primary myelofibrosis.
Dam MJB, Pedersen RK, Knudsen TA, et al.
European journal of haematology 2021; (107(6)):624-633 doi:10.1111/ejh.13700.
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Revisiting Diagnostic performances of serum erythropoïetin level and JAK2 mutation for polycythemias: analysis of a cohort of 1090 patients with red cell mass measurement.
Maslah N, Ravdan O, Drevon L, et al.
British journal of haematology 2022; (196(3)):676-680 doi:10.1111/bjh.17848.
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Rationale and design of the multicentric, double-blind, double-placebo, randomized trial APrepitant versus HYdroxyzine in association with cytoreductive treatments for patients with myeloproliferative neoplasia suffering from Persistent Aquagenic Pruritus. Trial acronym: APHYPAP.
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Trials 2021; (22(1)):938 doi:10.1186/s13063-021-05864-8.
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Rapid progression of myelofibrosis in polycythemia vera patient carrying SRSF2 c.284C>A p.(Pro95His) and unique ASXL1 splice site c.1720-2A>G variant.
Kanduła Z, Kroll-Balcerzak R, Lewandowski K
Journal of clinical laboratory analysis 2022; (36(5)):e24388 doi:10.1002/jcla.24388.
PMID: 35435261 - 58
Genetic Background of Polycythemia Vera.
Regimbeau M, Mary R, Hermetet F, Girodon F
Genes 2022; (13(4)) doi:10.3390/genes13040637.
PMID: 35456443 - 59
Clinical features of acquired erythrocytosis: Low levels of serum erythropoietin in a subset of non-neoplastic erythrocytosis patients.
Mori Y, Araki M, Morishita S, et al.
Cancer medicine 2023; (12(2)):1079-1089 doi:10.1002/cam4.4958.
PMID: 35775283 - 60
Clinical characteristics of Japanese patients with polycythemia vera: results of the JSH-MPN-R18 study.
Edahiro Y, Ito T, Gotoh A, et al.
International journal of hematology 2022; (116(5)):696-711 doi:10.1007/s12185-022-03412-x.
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ASXL1 mutations accelerate bone marrow fibrosis via EGR1-TNFA axis-mediated neoplastic fibrocyte generation in myeloproliferative neoplasms.
Shi Z, Liu J, Zhao Y, et al.
Haematologica 2023; (108(5)):1359-1373 doi:10.3324/haematol.2021.280320.
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The international consensus classification of myeloid neoplasms and acute Leukemias: myeloproliferative neoplasms.
Thiele J, Kvasnicka HM, Orazi A, et al.
American journal of hematology 2023; (98(1)):166-179 doi:10.1002/ajh.26751.
PMID: 36200127 - 63
JAK2V617F variant allele frequency, non-driver mutations, single-nucleotide variants and polycythemia vera outcome.
Kanduła Z, Janowski M, Więckowska B, et al.
Journal of cancer research and clinical oncology 2023; (149(8)):4789-4803 doi:10.1007/s00432-022-04327-0.
PMID: 36242602 - 64
Real world experience with ropeginterferon alpha-2b (Besremi) in essential thrombocythaemia and polycythaemia vera following exposure to pegylated interferon alfa-2a (Pegasys).
Okikiolu J, Woodley C, Cadman-Davies L, et al.
Leukemia research reports 2023; (19()):100360 doi:10.1016/j.lrr.2022.100360.
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Hepcidin mimetics in polycythemia vera: resolving the irony of iron deficiency and erythrocytosis.
Handa S, Ginzburg Y, Hoffman R, Kremyanskaya M
Current opinion in hematology 2023; (30(2)):45-52 doi:10.1097/MOH.0000000000000747.
PMID: 36728649 - 66
Differences between aquagenic and non-aquagenic pruritus in myeloproliferative neoplasms: An observational study of 500 patients.
Le Gall-Ianotto C, Ficheux AS, Lippert E, et al.
Journal of the European Academy of Dermatology and Venereology : JEADV 2023; (37(6)):1175-1183 doi:10.1111/jdv.18990.
PMID: 36808754 - 67
Treatment of hydroxyurea-resistant/intolerant polycythemia vera: a discussion of best practices.
Kuykendall AT
Annals of hematology 2023; (102(5)):985-993 doi:10.1007/s00277-023-05172-y.
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Sodium-glucose co-transporter-2 inhibitor use and JAK2 unmutated erythrocytosis in 100 consecutive cases.
Gangat N, Abdallah M, Szuber N, et al.
American journal of hematology 2023; (98(7)):E165-E167 doi:10.1002/ajh.26933.
PMID: 37073574 - 69
Polycythemia vera: 2024 update on diagnosis, risk-stratification, and management.
Tefferi A, Barbui T
American journal of hematology 2023; (98(9)):1465-1487 doi:10.1002/ajh.27002.
PMID: 37357958 - 70
Whole blood transcriptional profiling reveals highly deregulated atherosclerosis genes in Philadelphia-chromosome negative myeloproliferative neoplasms.
Skov V, Thomassen M, Kjaer L, et al.
European journal of haematology 2023; (111(5)):805-814 doi:10.1111/ejh.14081.
PMID: 37640394 - 71
Naltrexone: a Novel Approach to Pruritus in Polycythemia Vera.
Nikzad N, Jackson LK
Federal practitioner : for the health care professionals of the VA, DoD, and PHS 2023; (40(Suppl 3)):S73-S75 doi:10.12788/fp.0396.
PMID: 38021098 - 72
Diagnosis and Management of Cardiovascular Risk in Patients with Polycythemia Vera.
Benevolo G, Marchetti M, Melchio R, et al.
Vascular health and risk management 2023; (19()):765-778 doi:10.2147/VHRM.S429995.
PMID: 38025519 - 73
The impact of thrombosis on probabilities of death and disease progression in polycythemia vera: a multistate transition analysis of 1,545 patients.
Barbui T, Carobbio A, Thiele J, et al.
Blood cancer journal 2023; (13(1)):187 doi:10.1038/s41408-023-00960-1.
PMID: 38102114 - 74
SOHO State of the Art Update and Next Questions: Novel Therapies for Polycythemia Vera.
Masarova L, Chifotides HT
Clinical lymphoma, myeloma & leukemia 2024; (24(3)):141-148 doi:10.1016/j.clml.2023.11.004.
PMID: 38135633 - 75
Association between elevated white blood cell counts and thrombotic events in polycythemia vera: analysis from REVEAL.
Gerds AT, Mesa R, Burke JM, et al.
Blood 2024; (143(16)):1646-1655 doi:10.1182/blood.2023020232.
PMID: 38142448 - 76
Polycythemia Vera: Barriers to and Strategies for Optimal Management.
Duminuco A, Harrington P, Harrison C, Curto-Garcia N
Blood and lymphatic cancer : targets and therapy 2023; (13()):77-90 doi:10.2147/BLCTT.S409443.
PMID: 38146420 - 77
A safety evaluation of ruxolitinib for the treatment of polycythemia vera.
Boldrini V, Vannucchi AM, Guglielmelli P
Expert opinion on drug safety 2024; (23(1)):1-7 doi:10.1080/14740338.2023.2299391.
PMID: 38156903 - 78
Obstructive Sleep Apnea Does Not Exclude Polycythemia Vera: A Case Report.
Afana MS, Abu-Tineh M, Alshurafa A, et al.
Case reports in oncology 2024; (17(1)):91-95 doi:10.1159/000535742.
PMID: 38213957 - 79
Erythrocytosis and CKD: A Review.
Aoun M, Jadoul M, Anders HJ
American journal of kidney diseases : the official journal of the National Kidney Foundation 2024; (84(4)):495-506 doi:10.1053/j.ajkd.2024.02.015.
PMID: 38621632 - 80
Contemporary Challenges in Polycythemia Vera Management From the Perspective of Patients and Physicians.
Kuykendall AT, Fine JT, Kremyanskaya M
Clinical lymphoma, myeloma & leukemia 2024; (24(8)):512-522 doi:10.1016/j.clml.2024.04.003.
PMID: 38749802 - 81
The assessment of health-related quality of life in patients with polycythemia vera.
Doğan EE, Keklik Karadağ F, Aydin D, et al.
Medicine 2024; (103(30)):e38814 doi:10.1097/MD.0000000000038814.
PMID: 39058813 - 82
A higher JAK2V617F allele burden may be a risk factor for hemorrhagic events in younger patients with polycythemia vera.
Furuya C, Hashimoto Y, Morishita S, et al.
Hematology (Amsterdam, Netherlands) 2024; (29(1)):2427905 doi:10.1080/16078454.2024.2427905.
PMID: 39545588 - 83
Ten years of experience with ruxolitinib since approval for polycythemia vera: A review of clinical efficacy and safety.
Masarova L, Mascarenhas J, Rampal R, et al.
Cancer 2025; (131(1)):e35661 doi:10.1002/cncr.35661.
PMID: 39616447 - 84
The Janus kinase 2 (JAK2) Mutation Burden is Related to Hematological Outcomes in Thai Patients with Myeloproliferative Neoplasms.
Sritana N, Cholnakasem N, Yimyaem M, et al.
Asian Pacific journal of cancer prevention : APJCP 2025; (26(2)):579-586 doi:10.31557/APJCP.2025.26.2.579.
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Next Generation Sequencing Identifies Subgroups of Patients With Triple Negative Primary Thrombocytosis With Different Clinical Thrombotic Outcomes.
Sangiorgio V, Mottadelli F, Pagni F, et al.
International journal of laboratory hematology 2025; (47(5)):869-876 doi:10.1111/ijlh.14476.
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The frequency of JAK2 V617F mutation and its association with low EPO levels in polycythemia vera patients.
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Scandinavian journal of clinical and laboratory investigation 2025; (85(4)):259-262 doi:10.1080/00365513.2025.2502945.
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Different Colours of Polycythemia Vera: A Case Series.
Viswanathan N, Adalarasan S, T S, S Y
Cureus 2025; (17(8)):e90913 doi:10.7759/cureus.90913.
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Aquagenic Pruritus Questionnaire: Predicting Myeloproliferative Neoplasms in Patients with Aquagenic Pruritus.
Witte F, Weisshaar E, Metz M, et al.
Dermatology and therapy 2025; (15(12)):3593-3604 doi:10.1007/s13555-025-01548-2.
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Advances in the Diagnosis and Treatment of Myeloproliferative Neoplasms (MPNs).
Ma X, Zhou Z, Gu S, et al.
Cancers 2025; (17(19)) doi:10.3390/cancers17193142.
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The impact of JAK2V617F variant allele frequency in MPN patients following PEGylated interferon alpha discontinuation.
Brown R, Bennett R, Crean C, et al.
British journal of haematology 2025; (207(6)):2597-2601 doi:10.1111/bjh.70198.
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