Research & Literature
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Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
Visualize citation networks across 118 referenced papers
Top Authors
- Derek C. Angus University of Pittsburgh
- Juliane Bubeck Wardenburg Society of Critical Care Medicine
- Mervyn Singer University College London
- Greet Van den Berghe KU Leuven
- Hallie C. Prescott Michigan Medicine
- Luregn J. Schlapbach University of Queensland
- Greet Hermans KU Leuven
- Dale M. Needham Johns Hopkins Medicine
- Manu Shankar‐Hari University of Edinburgh
- Carolin Fleischmann-Struzek Jena University Hospital
Top Institutions
- Institute for Health Metrics and Evaluation Seattle, United States Andrew J. Pollard , Gregory A. Roth , Chao Cao , Derrick Tsoi , Kareha M Agesa , Katya Anne Shackelford , Danny V. Colombara , Gurjit Kaur Bhatti , Authia P Gray , Hmwe Hmwe Kyu
- University of Washington Seattle, United States R. Scott Watson , Laura Evans , Elizabeth Y. Killien , Aaron E. Bunnell , J. Randall Curtis , Rita Mangione‐Smith , Pavan K. Bhatraju , Leslie A. Dervan , François Aspesberro , May J. Reed
- University of Pittsburgh Pittsburgh, United States Derek C. Angus , Christopher W. Seymour , Kristina E. Rudd , Christopher Seymour , Timothy D. Girard , Idris Evans , Brad W. Butcher , Matthew R. Rosengart , Kelly Potter , Christopher M. Horvat
- University of Florida Gainesville, United States Philip A. Efron , Russell B. Hawkins , James L. Wynn , Julie A. Stortz , Martin D. Rosenthal , Alicia M. Mohr , Anna Gardner , Brittany Mathias , Hiroyuki Horiguchi , Faheem W. Guirgis
- Vanderbilt University Medical Center Nashville, United States Carla M. Sevin , E. Wesley Ely , James C. Jackson , Annachiara Marra , Mayur B. Patel , Leanne M. Boehm , Pratik P. Pandharipande , Brenda T. Pun , Gordon R. Bernard , Todd W. Rice
- Jena University Hospital Jena, Germany Carolin Fleischmann-Struzek , Konrad Schmidt , Johannes Ehler , Michael Bauer , Ha‐Yeun Chung , Christian Geis , Peter Schlattmann , Jenny Rosendahl , Jochen Gensichen , Yasser Sakr
- Johns Hopkins University Baltimore, United States Theodore J. Iwashyna , Victor D. Dinglas , O. Joseph Bienvenu , Sapna R. Kudchadkar , Alison E. Turnbull , Beth Wieczorek , Minxuan Huang , Elizabeth Herrup , Karin J. Neufeld , Suchi Saria
- KU Leuven Leuven, Belgium Greet Van den Berghe , Greet Hermans , Ilse Vanhorebeek , Nathalie Van Aerde , Lies Langouche , Rik Gosselink , Jan Gunst , Chloë Goossens , Pieter Wouters , Michaël P. Casaer
- University of British Columbia Vancouver, Canada Niranjan Kissoon , Matthew O. Wiens , John H. Boyd , Kelly R. Genga , Keith R. Walley , Gregory Haljan , Andy Y. An , Robert E. W. Hancock , A. Fuchsia Howard , Mihai Cîrstea
- Stanford University Stanford, United States Daria Mochly‐Rosen , Amit U. Joshi , Ben A. Barres , Katrin I. Andreasson , Paras S. Minhas , Qingyun Li , Riddhita Mukherjee , Marie‐Hélène Disatnik , Adrienne G. Randolph , Purvesh Khatri
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Weak by the machines: muscle motor protein dysfunction - a side effect of intensive care unit treatment.
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Impact of PCSK9 loss-of-function genotype on 1-year mortality and recurrent infection in sepsis survivors.
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Health-Related Quality of Life Among Survivors of Pediatric Sepsis.
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Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2019; (20(6)):501-509 doi:10.1097/PCC.0000000000001886.
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Mitochondrial quality control mechanisms as potential therapeutic targets in sepsis-induced multiple organ failure.
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Journal of molecular medicine (Berlin, Germany) 2019; (97(4)):451-462 doi:10.1007/s00109-019-01756-2.
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Sepsis: From Historical Aspects to Novel Vistas. Pathogenic and Therapeutic Considerations.
Magrone T, Jirillo E
Endocrine, metabolic & immune disorders drug targets 2019; (19(4)):490-502 doi:10.2174/1871530319666181129112708.
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Septic shock among patients with systemic lupus erythematosus: Short and long-term outcome. Analysis of a French nationwide database.
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The Journal of infection 2019; (78(6)):432-438 doi:10.1016/j.jinf.2019.04.005.
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Risk Factors at Index Hospitalization Associated With Longer-term Mortality in Adult Sepsis Survivors.
Shankar-Hari M, Harrison DA, Ferrando-Vivas P, et al.
JAMA network open 2019; (2(5)):e194900 doi:10.1001/jamanetworkopen.2019.4900.
PMID: 31150081 - 18
[Research progress on evaluation tools for post-intensive care syndrome].
Zhang X, Zhang L, Liu P, Li W
Zhonghua wei zhong bing ji jiu yi xue 2019; (31(7)):916-919 doi:10.3760/cma.j.issn.2095-4352.2019.07.025.
PMID: 31441423 - 19
Structured, proactive care coordination versus usual care for Improving Morbidity during Post-Acute Care Transitions for Sepsis (IMPACTS): a pragmatic, randomized controlled trial.
Kowalkowski M, Chou SH, McWilliams A, et al.
Trials 2019; (20(1)):660 doi:10.1186/s13063-019-3792-7.
PMID: 31783900 - 20
Gross motor developmental dysfunctional outcomes in infantile and toddler pediatric intensive care unit survivors.
Yang CF, Xue Y, Feng JY, et al.
BMC pediatrics 2019; (19(1)):508 doi:10.1186/s12887-019-1893-9.
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Post-sepsis syndrome - an evolving entity that afflicts survivors of sepsis.
Mostel Z, Perl A, Marck M, et al.
Molecular medicine (Cambridge, Mass.) 2019; (26(1)):6 doi:10.1186/s10020-019-0132-z.
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Rate and risk factors for rehospitalisation in sepsis survivors: systematic review and meta-analysis.
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Intensive care medicine 2020; (46(4)):619-636 doi:10.1007/s00134-019-05908-3.
PMID: 31974919 - 23
Mitochondrial dysfunction mediated through dynamin-related protein 1 (Drp1) propagates impairment in blood brain barrier in septic encephalopathy.
Haileselassie B, Joshi AU, Minhas PS, et al.
Journal of neuroinflammation 2020; (17(1)):36 doi:10.1186/s12974-019-1689-8.
PMID: 31987040 - 24
Long-term consequences in survivors of critical illness. Analysis of incidence and risk factors.
Demoro G, Damico V, Murano L, et al.
Annali dell'Istituto superiore di sanita 2020; (56(1)):59-65 doi:10.4415/ANN_20_01_09.
PMID: 32242536 - 25
Post-Intensive-Care Syndrome for the Pediatric Neurologist.
Hartman ME, Williams CN, Hall TA, et al.
Pediatric neurology 2020; (108()):47-53 doi:10.1016/j.pediatrneurol.2020.02.003.
PMID: 32299742 - 26
Distinct Neutrophil Populations in the Spleen During PICS.
Sengupta S, Caldwell CC, Nomellini V
Frontiers in immunology 2020; (11()):804 doi:10.3389/fimmu.2020.00804.
PMID: 32499777 - 27
Society of Critical Care Medicine's International Consensus Conference on Prediction and Identification of Long-Term Impairments After Critical Illness.
Mikkelsen ME, Still M, Anderson BJ, et al.
Critical care medicine 2020; (48(11)):1670-1679 doi:10.1097/CCM.0000000000004586.
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Exploring the pathophysiology of post-sepsis syndrome to identify therapeutic opportunities.
van der Slikke EC, An AY, Hancock REW, Bouma HR
EBioMedicine 2020; (61()):103044 doi:10.1016/j.ebiom.2020.103044.
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Prevalence and risk factors for post-traumatic stress, anxiety, and depression in sepsis survivors after ICU discharge.
Calsavara AJ, Costa PA, Nobre V, Teixeira AL
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 2021; (43(3)):269-276 doi:10.1590/1516-4446-2020-0986.
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Pulmonary Rehabilitation in COVID-19 patients: A scoping review of current practice and its application during the pandemic.
Siddiq MAB, Rathore FA, Clegg D, Rasker JJ
Turkish journal of physical medicine and rehabilitation 2020; (66(4)):480-494 doi:10.5606/tftrd.2020.6889.
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Long-term outcomes from critical care.
Morgan A
Surgery (Oxford, Oxfordshire) 2021; (39(1)):53-57 doi:10.1016/j.mpsur.2020.11.005.
PMID: 33519011 - 32
Post-Sepsis Syndrome.
Leviner S
Critical care nursing quarterly 2021; (44(2)):182-186 doi:10.1097/CNQ.0000000000000352.
PMID: 33595965 - 33
Why Septic Patients Remain Sick After Hospital Discharge?
Gritte RB, Souza-Siqueira T, Curi R, et al.
Frontiers in immunology 2020; (11()):605666 doi:10.3389/fimmu.2020.605666.
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Immunological Endotyping of Chronic Critical Illness After Severe Sepsis.
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Frontiers in medicine 2020; (7()):616694 doi:10.3389/fmed.2020.616694.
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Dantrolene repurposed to treat sepsis or septic shock and COVID-19 patients.
Wei H, Liang G, Vera RM
European review for medical and pharmacological sciences 2021; (25(7)):3136-3144 doi:10.26355/eurrev_202104_25569.
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Trajectories of depression in sepsis survivors: an observational cohort study.
Boede M, Gensichen JS, Jackson JC, et al.
Critical care (London, England) 2021; (25(1)):161 doi:10.1186/s13054-021-03577-7.
PMID: 33926493 - 37
The physical and mental impact of surviving sepsis - a qualitative study of experiences and perceptions among a Swedish sample.
Apitzsch S, Larsson L, Larsson AK, Linder A
Archives of public health = Archives belges de sante publique 2021; (79(1)):66 doi:10.1186/s13690-021-00585-5.
PMID: 33933171 - 38
Chronic Critical Illness and PICS Nutritional Strategies.
Rosenthal MD, Vanzant EL, Moore FA
Journal of clinical medicine 2021; (10(11)) doi:10.3390/jcm10112294.
PMID: 34070395 - 39
Protocol for a two-arm pragmatic stepped-wedge hybrid effectiveness-implementation trial evaluating Engagement and Collaborative Management to Proactively Advance Sepsis Survivorship (ENCOMPASS).
Kowalkowski M, Eaton T, McWilliams A, et al.
BMC health services research 2021; (21(1)):544 doi:10.1186/s12913-021-06521-1.
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PICU Follow-Up Clinic: Patient and Family Outcomes 2 Months After Discharge.
Ducharme-Crevier L, La KA, Francois T, et al.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2021; (22(11)):935-943 doi:10.1097/PCC.0000000000002789.
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Post-intensive Care Syndrome.
Ahmad MH, Teo SP
Annals of geriatric medicine and research 2021; (25(2)):72-78 doi:10.4235/agmr.21.0048.
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Implementation of a Follow-Up System for Pediatric Sepsis Survivors in a Large Academic Pediatric Intensive Care Unit.
Fitzgerald JC, Kelly NA, Hickey C, et al.
Frontiers in pediatrics 2021; (9()):691692 doi:10.3389/fped.2021.691692.
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Frequency and risk factors of post-intensive care syndrome components in a multicenter randomized controlled trial of German sepsis survivors.
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Journal of critical care 2021; (65()):268-273 doi:10.1016/j.jcrc.2021.07.006.
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Sepsis-Associated Encephalopathy and Blood-Brain Barrier Dysfunction.
Gao Q, Hernandes MS
Inflammation 2021; (44(6)):2143-2150 doi:10.1007/s10753-021-01501-3.
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Improvement in Health-Related Quality of Life After Community Acquired Pediatric Septic Shock.
Pinto NP, Berg RA, Zuppa AF, et al.
Frontiers in pediatrics 2021; (9()):675374 doi:10.3389/fped.2021.675374.
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Post-Intensive Care Syndrome and Its New Challenges in Coronavirus Disease 2019 (COVID-19) Pandemic: A Review of Recent Advances and Perspectives.
Nakanishi N, Liu K, Kawakami D, et al.
Journal of clinical medicine 2021; (10(17)) doi:10.3390/jcm10173870.
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Biomarker Evidence of the Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS) in Chronic Critical Illness (CCI) After Surgical Sepsis.
Darden DB, Brakenridge SC, Efron PA, et al.
Annals of surgery 2021; (274(4)):664-673 doi:10.1097/SLA.0000000000005067.
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Neuromuscular Disorders in the Intensive Care Unit.
Birch TB
Continuum (Minneapolis, Minn.) 2021; (27(5)):1344-1364 doi:10.1212/CON.0000000000001004.
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Post-Intensive Care Syndrome in Children: A Concept Analysis.
Tang M, Xu M, Su S, et al.
Journal of pediatric nursing 2021; (61()):417-423 doi:10.1016/j.pedn.2021.10.007.
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Challenges in pediatric post-sepsis care in resource limited settings: a narrative review.
Wiens MO, Kissoon N, Holsti L
Translational pediatrics 2021; (10(10)):2666-2677 doi:10.21037/tp-20-390.
PMID: 34765492 - 51
Transitions from short to long-term outcomes in pediatric critical care: considerations for clinical practice.
Long DA, Fink EL
Translational pediatrics 2021; (10(10)):2858-2874 doi:10.21037/tp-21-61.
PMID: 34765507 - 52
Evaluating the Feasibility and Efficacy of a Pediatric Intensive Care Unit Diary.
Wang SH, Owens T, Johnson A, Duffy EA
Critical care nursing quarterly 2022; (45(1)):88-97 doi:10.1097/CNQ.0000000000000392.
PMID: 34818302 - 53
Long-term cardiovascular complications following sepsis: is senescence the missing link?
Merdji H, Schini-Kerth V, Meziani F, Toti F
Annals of intensive care 2021; (11(1)):166 doi:10.1186/s13613-021-00937-y.
PMID: 34851467 - 54
Designing Support Structures Post Sepsis in Children: Perspectives of the Queensland Paediatric Sepsis Program.
Raman S, English A, O'Keefe M, et al.
Frontiers in pediatrics 2021; (9()):759234 doi:10.3389/fped.2021.759234.
PMID: 34869116 - 55
Patterns of renal and splanchnic sympathetic vasomotor activity in an animal model of survival to experimental sepsis.
Milanez MIO, Liberatore AMA, Nishi EE, et al.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica 2022; (55()):e11873 doi:10.1590/1414-431X2021e11873.
PMID: 35043862 - 56
Recovery and long term functional outcome in people with critical illness polyneuropathy and myopathy: a scoping review.
Intiso D, Centra AM, Bartolo M, et al.
BMC neurology 2022; (22(1)):50 doi:10.1186/s12883-022-02570-z.
PMID: 35148710 - 57
Educational Outcomes of Childhood Survivors of Critical Illness-A Population-Based Linkage Study.
Tomaszewski W, Ablaza C, Straney L, et al.
Critical care medicine 2022; (50(6)):901-912 doi:10.1097/CCM.0000000000005461.
PMID: 35170536 - 58
Physical Quality of Life of Sepsis Survivor Severely Malnourished Children after Hospital Discharge: Findings from a Retrospective Chart Analysis.
Sarmin M, Alam T, Shaly NJ, et al.
Life (Basel, Switzerland) 2022; (12(3)) doi:10.3390/life12030379.
PMID: 35330130 - 59
Functional Outcomes in Survivors of Pediatric Sepsis: A Scoping Review and Discussion of Implications for Low- and Middle-Income Countries.
Ravikumar N, Sankar J, Das RR
Frontiers in pediatrics 2022; (10()):762179 doi:10.3389/fped.2022.762179.
PMID: 35345613 - 60
Effects of evidence-based ICU care on long-term outcomes of patients with sepsis or septic shock (ILOSS): protocol for a multicentre prospective observational cohort study in Japan.
Liu K, Kotani T, Nakamura K, et al.
BMJ open 2022; (12(3)):e054478 doi:10.1136/bmjopen-2021-054478.
PMID: 35351710 - 61
Silencing of amygdala circuits during sepsis prevents the development of anxiety-related behaviours.
Bourhy L, Mazeraud A, Costa LHA, et al.
Brain : a journal of neurology 2022; (145(4)):1391-1409 doi:10.1093/brain/awab475.
PMID: 35441215 - 62
Association of Illness Severity With Family Outcomes Following Pediatric Septic Shock.
Killien EY, Zimmerman JJ, Di Gennaro JL, Watson RS
Critical care explorations 2022; (4(6)):e0716 doi:10.1097/CCE.0000000000000716.
PMID: 35733611 - 63
Interprofessional Education Module on Post-Intensive Care Syndrome for Internal Medicine Residents.
Hampton SF, Carlbom D, Steinkruger S, et al.
ATS scholar 2022; (3(2)):324-331 doi:10.34197/ats-scholar.2021-0114IN.
PMID: 35924197 - 64
Central role of microglia in sepsis-associated encephalopathy: From mechanism to therapy.
Yan X, Yang K, Xiao Q, et al.
Frontiers in immunology 2022; (13()):929316 doi:10.3389/fimmu.2022.929316.
PMID: 35958583 - 65
Intensive care unit-acquired weakness: A review from molecular mechanisms to its impact in COVID-2019.
Gonzalez A, Abrigo J, Achiardi O, et al.
European journal of translational myology 2022; (32(3)) doi:10.4081/ejtm.2022.10511.
PMID: 36036350 - 66
Sepsis-Induced Brain Dysfunction: Pathogenesis, Diagnosis, and Treatment.
Pan S, Lv Z, Wang R, et al.
Oxidative medicine and cellular longevity 2022; (2022()):1328729 doi:10.1155/2022/1328729.
PMID: 36062193 - 67
Case report: Personalized adapted motor activity in a COVID-19 patient complicated by critical illness polyneuropathy and myopathy.
Crisafulli O, Baroscelli M, Grattarola L, et al.
Frontiers in physiology 2022; (13()):1035255 doi:10.3389/fphys.2022.1035255.
PMID: 36467693 - 68
Metabolic Reprogramming of Microglia in Sepsis-Associated Encephalopathy: Insights from Neuroinflammation.
Gao S, Jiang Y, Chen Z, et al.
Current neuropharmacology 2023; (21(9)):1992-2005 doi:10.2174/1570159X21666221216162606.
PMID: 36529923 - 69
Passing the SNF Test: A Secondary Analysis of a Sepsis Transition Intervention Trial Among Patients Discharged to Post-Acute Care.
Colucciello NA, Kowalkowski MA, Kooken M, et al.
Journal of the American Medical Directors Association 2023; (24(5)):742-746.e1 doi:10.1016/j.jamda.2023.02.009.
PMID: 36918147 - 70
Chronic pain in in survivors of critical illness: prevalence and associated psychological disorders.
Damico V, Murano L, Dal Molin A
Professioni infermieristiche 2022; (75(2)):106-114.
PMID: 36964921 - 71
Mitochondrial Dysfunction in Intensive Care Unit-Acquired Weakness and Critical Illness Myopathy: A Narrative Review.
Klawitter F, Ehler J, Bajorat R, Patejdl R
International journal of molecular sciences 2023; (24(6)) doi:10.3390/ijms24065516.
PMID: 36982590 - 72
Long-term outcomes after paediatric sepsis: A narrative review.
Minogue J, Keogh S, Schlapbach LJ, Long D
Australian critical care : official journal of the Confederation of Australian Critical Care Nurses 2024; (37(3)):499-507 doi:10.1016/j.aucc.2023.04.002.
PMID: 37164888 - 73
[Comparison between the 2020 international guidelines for the management of sepsis and septic shock and the Japanese guidelines for the management of sepsis].
An X, Ma X
Zhonghua wei zhong bing ji jiu yi xue 2023; (35(5)):453-457 doi:10.3760/cma.j.cn121430-20221227-01119.
PMID: 37308222 - 74
Guideline on multimodal rehabilitation for patients with post-intensive care syndrome.
Renner C, Jeitziner MM, Albert M, et al.
Critical care (London, England) 2023; (27(1)):301 doi:10.1186/s13054-023-04569-5.
PMID: 37525219 - 75
Understanding Post-Sepsis Syndrome: How Can Clinicians Help?
van der Slikke EC, Beumeler LFE, Holmqvist M, et al.
Infection and drug resistance 2023; (16()):6493-6511 doi:10.2147/IDR.S390947.
PMID: 37795206 - 76
[Multiple factors contributing to dysphagia : Extended tasks for the interprofessional team in the intensive care unit].
Albrecht S, Nusser-Müller-Busch R
Medizinische Klinik, Intensivmedizin und Notfallmedizin 2024; (119(1)):56-62 doi:10.1007/s00063-023-01075-y.
PMID: 37943309 - 77
Follow-up after PICU discharge for patients with acquired brain injury: the role of an abbreviated neuropsychological evaluation and a return-to-school program.
Williams CN, Hall TA, Baker VA, et al.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2023; (24(10)):807-817 doi:10.1097/pcc.0000000000003303.
PMID: 38156082 - 78
International Consensus Criteria for Pediatric Sepsis and Septic Shock.
Schlapbach LJ, Watson RS, Sorce LR, et al.
JAMA 2024; (331(8)):665-674 doi:10.1001/jama.2024.0179.
PMID: 38245889 - 79
The Role of Pediatric Psychologists in Critical Care: Lessons Learned and Future Directions in Integrating Mental Health Care Into PICUs.
Canavera K, Marik P, Schneider NM, Smith J
Chest 2024; (166(3)):511-516 doi:10.1016/j.chest.2024.03.028.
PMID: 38513964 - 80
"I Didn't Realize How Hard It Was Going to Be Just Transitioning Back into Life": A Qualitative Exploration of Outcomes for Survivors of Pediatric Septic Shock.
Clark JD, Kraft SA, Dervan LA, et al.
Journal of pediatric intensive care 2024; (13(1)):63-74 doi:10.1055/s-0041-1736547.
PMID: 38571982 - 81
Neurorehabilitation across the Continuum: From the Neurocritical care unit to home.
Ankar A, Hermes E, Wheless C, et al.
Seminars in pediatric neurology 2024; (49()):101121 doi:10.1016/j.spen.2024.101121.
PMID: 38677800 - 82
Beyond survival: understanding post-intensive care syndrome.
Gupta L, Subair MN, Munjal J, et al.
Acute and critical care 2024; (39(2)):226-233 doi:10.4266/acc.2023.01158.
PMID: 38863353 - 83
Risk factors for PTSD symptoms following PICU admission for childhood septic shock.
Corbet Burcher GJ, O'Dea LA, Cooper MK, et al.
European child & adolescent psychiatry 2025; (34(1)):307-313 doi:10.1007/s00787-024-02496-6.
PMID: 38878227 - 84
Translation and Adaptation of the Japanese Version of the Revised Parental Stressor Scale: Pediatric Intensive Care Unit.
Ikeda M, Hoshino H, Aikawa G, et al.
Cureus 2024; (16(7)):e64389 doi:10.7759/cureus.64389.
PMID: 39130874 - 85
Mobilisation of post-ICU patients - a crucial teamwork between physiotherapists and nurses at surgical wards: a qualitative study.
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