Research & Literature

Immediate delivery versus expectant monitoring for hypertensive disorders of pregnancy between 34 and 37 weeks of gestation (HYPITAT-II): an open-label, randomised controlled trial.

Broekhuijsen K, van Baaren GJ, van Pampus MG, et al.

Lancet (London, England) 2015; (385(9986)):2492-501.

The hypertensive disorders of pregnancy (29.3).

Magee LA, Pels A, Helewa M, et al.

Best practice & research. Clinical obstetrics & gynaecology 2015; (29(5)):643-57.

The Role of Headache in the Classification and Management of Hypertensive Disorders in Pregnancy.

Sperling JD, Dahlke JD, Huber WJ, Sibai BM

Obstetrics and gynecology 2015; (126(2)):297-302 doi:10.1097/AOG.0000000000000966.

SOMANZ guidelines for the management of hypertensive disorders of pregnancy 2014.

Lowe SA, Bowyer L, Lust K, et al.

The Australian & New Zealand journal of obstetrics & gynaecology 2015; (55(5)):e1-29 doi:10.1111/ajo.12399.

A comparison of the diagnostic utility of the sFlt-1/PlGF ratio versus PlGF alone for the detection of preeclampsia/HELLP syndrome.

Stepan H, Hund M, Gencay M, et al.

Hypertension in pregnancy 2016; (35(3)):295-305 doi:10.3109/10641955.2016.1141214.

Oral nifedipine vs. intravenous labetalol for treatment of pregnancy-induced severe pre-eclampsia.

Shi DD, Yang FZ, Zhou L, Wang N

Journal of clinical pharmacy and therapeutics 2016; (41(6)):657-661 doi:10.1111/jcpt.12439.

Preeclampsia and Future Cardiovascular Health: A Systematic Review and Meta-Analysis.

Wu P, Haththotuwa R, Kwok CS, et al.

Circulation. Cardiovascular quality and outcomes 2017; (10(2)) doi:10.1161/CIRCOUTCOMES.116.003497.

Prediction of adverse maternal outcomes from pre-eclampsia and other hypertensive disorders of pregnancy: A systematic review.

Ukah UV, De Silva DA, Payne B, et al.

Pregnancy hypertension 2018; (11()):115-123 doi:10.1016/j.preghy.2017.11.006.

Hypertensive Disorders of Pregnancy: Overview and Current Recommendations.

Folk DM

Journal of midwifery & women's health 2018; (63(3)):289-300 doi:10.1111/jmwh.12725.

Soluble fms-like tyrosine kinase-1 to placental growth factor ratio: ruling out pre-eclampsia for up to 4 weeks and value of retesting.

Zeisler H, Llurba E, Chantraine FJ, et al.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2019; (53(3)):367-375 doi:10.1002/uog.19178.

Hypertensive disorders in pregnancy.

Upadya M, Rao ST

Indian journal of anaesthesia 2018; (62(9)):675-681 doi:10.4103/ija.IJA_475_18.

Histological Features of Shallow Placental Implantation Unify Early-Onset and Late-Onset Preeclampsia.

Stanek J

Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2019; (22(2)):112-122 doi:10.1177/1093526618803759.

Hypertension, Anxiety, and Blood-Brain Barrier Permeability Are Increased in Postpartum Severe Preeclampsia/Hemolysis, Elevated Liver Enzymes, and Low Platelet Count Syndrome Rats.

Wallace K, Bean C, Bowles T, et al.

Hypertension (Dallas, Tex. : 1979) 2018; (72(4)):946-954 doi:10.1161/HYPERTENSIONAHA.118.11770.

Analysis of Proteinuria Estimation Methods in Hypertensive Disorders of Pregnancy.

Nipanal HV, Maurrya DK, Susmitha S, Ravindra PN

Journal of obstetrics and gynaecology of India 2018; (68(6)):452-455 doi:10.1007/s13224-017-1057-5.

ACOG Practice Bulletin No. 202: Gestational Hypertension and Preeclampsia.

Obstetrics and gynecology 2019; (133(1)):1 doi:10.1097/AOG.0000000000003018.

Pre-eclampsia: pathogenesis, novel diagnostics and therapies.

Phipps EA, Thadhani R, Benzing T, Karumanchi SA

Nature reviews. Nephrology 2019; (15(5)):275-289 doi:10.1038/s41581-019-0119-6.

Abdelazim and AbuFaza ELLP syndrome as a variant of HELLP syndrome: Case reports.

Abdelazim IA, AbuFaza M

Journal of family medicine and primary care 2019; (8(1)):280-284 doi:10.4103/jfmpc.jfmpc_381_18.

Preeclampsia: Pathophysiology, Challenges, and Perspectives

Rana S, Lemoine E, Granger JP, Karumanchi SA

Circulation research 2019; (124(7)):1094-1112 doi:10.1161/CIRCRESAHA.118.313276.

Hypertension in pregnancy: Pathophysiology and treatment.

Braunthal S, Brateanu A

SAGE open medicine 2019; (7()):2050312119843700 doi:10.1177/2050312119843700.

Open-labelled randomised controlled trial of 12 hours versus 24 hours modified Pritchard regimen in the management of eclampsia and pre-eclampsia in Ghana (MOPEP Study): study protocol.

Beyuo T, Lawrence E, Langen ES, Oppong SA

BMJ open 2019; (9(10)):e032799 doi:10.1136/bmjopen-2019-032799.

A Proposed Plan for Prenatal Care to Minimize Risks of COVID-19 to Patients and Providers: Focus on Hypertensive Disorders of Pregnancy.

Barton JR, Saade GR, Sibai BM

American journal of perinatology 2020; (37(8)):837-844 doi:10.1055/s-0040-1710538.

Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin Summary, Number 222.

Obstetrics and gynecology 2020; (135(6)):1492-1495 doi:10.1097/AOG.0000000000003892.

Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin, Number 222.

Obstetrics and gynecology 2020; (135(6)):e237-e260 doi:10.1097/AOG.0000000000003891.

A study to compare maternal and perinatal outcome in early vs. late onset preeclampsia.

Wadhwani P, Saha PK, Kalra JK, et al.

Obstetrics & gynecology science 2020; (63(3)):270-277 doi:10.5468/ogs.2020.63.3.270.

Comparisons of Dipstick Test, Urine Protein-to-Creatine Ratio, and Total Protein Measurement for the Diagnosis of Preeclampsia.

Stefańska K, Zieliński M, Zamkowska D, et al.

International journal of environmental research and public health 2020; (17(12)) doi:10.3390/ijerph17124195.

The blurring boundaries between placental and maternal preeclampsia: a critical appraisal of 1800 consecutive preeclamptic cases.

Robillard PY, Dekker G, Scioscia M, et al.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022; (35(13)):2450-2456 doi:10.1080/14767058.2020.1786516.

Traumatic childbirth perception during pregnancy and the postpartum period and its postnatal mental health outcomes: a prospective longitudinal study.

Türkmen H, Yalniz Dİlcen H, Özçoban FA

Journal of reproductive and infant psychology 2021; (39(4)):422-434 doi:10.1080/02646838.2020.1792429.

Prevalence of Hemolysis, Elevated Liver Enzymes, Low Platelet Count Syndrome in Pregnant Women in a Tertiary Care Hospital.

Sitaula S, Manandhar T, Thapa BD, et al.

JNMA; journal of the Nepal Medical Association 2020; (58(226)):405-408 doi:10.31729/jnma.4921.

A systematic review of clinical effectiveness of psychological interventions to reduce post traumatic stress symptoms following childbirth and a meta-synthesis of facilitators and barriers to uptake of psychological care.

Slade PP, Molyneux DR, Watt DA

Journal of affective disorders 2021; (281()):678-694 doi:10.1016/j.jad.2020.11.092.

Hypertensive Disorders of Pregnancy.

Khedagi AM, Bello NA

Cardiology clinics 2021; (39(1)):77-90 doi:10.1016/j.ccl.2020.09.005.

Patient perceptions, opinions and satisfaction of telehealth with remote blood pressure monitoring postpartum.

Thomas NA, Drewry A, Racine Passmore S, et al.

BMC pregnancy and childbirth 2021; (21(1)):153 doi:10.1186/s12884-021-03632-9.

Aspirin Prophylaxis During Pregnancy: A Systematic Review and Meta-Analysis.

Choi YJ, Shin S

American journal of preventive medicine 2021; (61(1)):e31-e45 doi:10.1016/j.amepre.2021.01.032.

Perception of traumatic childbirth of women and its relationship with postpartum depression.

Bay F, Sayiner FD

Women & health 2021; (61(5)):479-489 doi:10.1080/03630242.2021.1927287.

Implementation of a text-based postpartum blood pressure monitoring program at 3 different academic sites.

Janssen MK, Demers S, Srinivas SK, et al.

American journal of obstetrics & gynecology MFM 2021; (3(6)):100446 doi:10.1016/j.ajogmf.2021.100446.

Management of hyponatraemia in pre-eclampsia with severe features.

Whitley J, Swartz S, Martinez A

BMJ case reports 2021; (14(8)) doi:10.1136/bcr-2021-244688.

Nonproteinuric Preeclampsia among Women with Hypertensive Disorders of Pregnancy at a Referral Hospital in Southwestern Uganda.

Owaraganise A, Migisha R, Ssalongo WGM, et al.

Obstetrics and gynecology international 2021; (2021()):9751775 doi:10.1155/2021/9751775.

Interleukin-6 and its correlations with maternal characteristics and echocardiographic parameters in pre-eclampsia, gestational hypertension and normotensive pregnancy.

Gencheva D, Nikolov F, Uchikova E, et al.

Cardiovascular journal of Africa 2022; (33(2)):65-73 doi:10.5830/CVJA-2021-040.

Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: US Preventive Services Task Force Recommendation Statement.

, Davidson KW, Barry MJ, et al.

JAMA 2021; (326(12)):1186-1191 doi:10.1001/jama.2021.14781.

Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.

Henderson JT, Vesco KK, Senger CA, et al.

JAMA 2021; (326(12)):1192-1206 doi:10.1001/jama.2021.8551.

Determinants of Preeclampsia Among Pregnant Women in Chiro Referral Hospital, Oromia Regional State, Ethiopia: Unmatched Case-Control Study.

Katore FH, Gurara AM, Beyen TK

Integrated blood pressure control 2021; (14()):163-172 doi:10.2147/IBPC.S336651.

Clinical interpretation and implementation of the sFlt-1/PlGF ratio in the prediction, diagnosis and management of preeclampsia.

Verlohren S, Brennecke SP, Galindo A, et al.

Pregnancy hypertension 2022; (27()):42-50 doi:10.1016/j.preghy.2021.12.003.

Trends in the Incidence of New-Onset Hypertensive Disorders of Pregnancy Among Rural and Urban Areas in the United States, 2007 to 2019.

Cameron NA, Everitt I, Seegmiller LE, et al.

Journal of the American Heart Association 2022; (11(2)):e023791 doi:10.1161/JAHA.121.023791.

Quantifying the additional maternal morbidity in women with preeclampsia with severe features in whom immediate delivery is recommended.

Jaber S, Jauk VC, Cozzi GD, et al.

American journal of obstetrics & gynecology MFM 2022; (4(3)):100565 doi:10.1016/j.ajogmf.2022.100565.

Oral Antihypertensives for Nonsevere Pregnancy Hypertension: Systematic Review, Network Meta- and Trial Sequential Analyses.

Bone JN, Sandhu A, Abalos ED, et al.

Hypertension (Dallas, Tex. : 1979) 2022; (79(3)):614-628 doi:10.1161/HYPERTENSIONAHA.121.18415.

Postpartum preeclampsia or eclampsia: defining its place and management among the hypertensive disorders of pregnancy.

Hauspurg A, Jeyabalan A

American journal of obstetrics and gynecology 2022; (226(2S)):S1211-S1221 doi:10.1016/j.ajog.2020.10.027.

Hypertensive Disorders of Pregnancy: Common Clinical Conundrums.

Ohamadike O, Lim SL, Siegel A, et al.

Obstetrical & gynecological survey 2022; (77(4)):234-244 doi:10.1097/OGX.0000000000000996.

Guideline No. 426: Hypertensive Disorders of Pregnancy: Diagnosis, Prediction, Prevention, and Management.

Magee LA, Smith GN, Bloch C, et al.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC 2022; (44(5)):547-571.e1 doi:10.1016/j.jogc.2022.03.002.

HELLP Syndrome.

Adorno M, Maher-Griffiths C, Grush Abadie HR

Critical care nursing clinics of North America 2022; (34(3)):277-288 doi:10.1016/j.cnc.2022.04.009.

Obstetric Disorders and Critical Illness.

Griffin KM, Oxford-Horrey C, Bourjeily G

Clinics in chest medicine 2022; (43(3)):471-488 doi:10.1016/j.ccm.2022.04.008.

Analytical approaches to evaluating hypertensive disorders of pregnancy.

Knupp RJ, Subramaniam A, Tita ANT, et al.

American journal of obstetrics & gynecology MFM 2023; (5(2)):100816 doi:10.1016/j.ajogmf.2022.100816.

Epidemiology and prognostic factors for successful expectant management of early-onset severe features preeclampsia: A retrospective multicenter cohort study.

Chantanavilai S, Kongwattanakul K, Komwilaisak R, et al.

Pregnancy hypertension 2022; (30()):226-231 doi:10.1016/j.preghy.2022.11.003.

Risk and trajectory of premature ischaemic cardiovascular disease in women with a history of pre-eclampsia: a nationwide register-based study.

Hallum S, Basit S, Kamper-Jørgensen M, et al.

European journal of preventive cardiology 2023; doi:10.1093/eurjpc/zwad003.

HELLP syndrome at <23 weeks' gestation: a systematic literature review.

Mossayebi MH, Iyer NS, McLaren RA, et al.

American journal of obstetrics and gynecology 2023; (229(5)):502-515.e10 doi:10.1016/j.ajog.2023.04.046.

Evidence of Nitric Oxide Impairment During Hypertensive Pregnancies.

Dela Justina V, Dos Passos Júnior RR, Lima VV, Giachini FR

Advances in experimental medicine and biology 2023; (1428()):99-125 doi:10.1007/978-3-031-32554-0_5.

Factors Associated with Progression to Preeclampsia with Severe Features in Pregnancies Complicated by Mild Hypertensive Disorders.

Barda S, Yoeli Y, Stav N, et al.

Journal of clinical medicine 2023; (12(22)) doi:10.3390/jcm12227022.

Case report: A case of posterior reversible encephalopathy in postpartum preeclampsia.

Rho JD, Kim YH, Shin JH, Kim TK

Medicine 2023; (102(47)):e36023 doi:10.1097/MD.0000000000036023.

Preventing posttraumatic stress disorder following childbirth: a systematic review and meta-analysis.

Dekel S, Papadakis JE, Quagliarini B, et al.

American journal of obstetrics and gynecology 2024; (230(6)):610-641.e14 doi:10.1016/j.ajog.2023.12.013.

Magnesium sulfate in preeclampsia: Broad indications, not only in neurological symptoms.

De Oliveira L, Korkes H, Rizzo M, et al.

Pregnancy hypertension 2024; (36()):101126 doi:10.1016/j.preghy.2024.101126.

The patient experience of a postpartum readmission for hypertension: a qualitative study.

Viswanathan R, Little SE, Wilkins-Haug L, et al.

BMC pregnancy and childbirth 2024; (24(1)):358 doi:10.1186/s12884-024-06564-2.

Moving the needle: Quality improvement strategies to achieve guideline-concordant care of obstetric patients with severe hypertension.

Zacherl KM, O'Sullivan KE, Karwoski LA, et al.

Pregnancy hypertension 2024; (37()):101135 doi:10.1016/j.preghy.2024.101135.

sFlt-1/PlGF ratio predicts serious outcomes in confirmed early-onset preeclampsia.

Shinohara S, Hiraoka N, Mochizuki K, et al.

European journal of obstetrics, gynecology, and reproductive biology 2024; (300()):159-163 doi:10.1016/j.ejogrb.2024.07.023.

Update on Preeclampsia and Hypertensive Disorders of Pregnancy.

Rosenberg EA, Seely EW

Endocrinology and metabolism clinics of North America 2024; (53(3)):377-389 doi:10.1016/j.ecl.2024.05.012.

Hypertensive Disorders of Pregnancy: Diagnosis, Management and Timing of Birth.

İnan C, Uygur L, Alpay V, et al.

Balkan medical journal 2024; (41(5)):333-347 doi:10.4274/balkanmedj.galenos.2024.2024-7-108.

Maternal and neonatal outcome among women with early-onset preeclampsia and late-onset preeclampsia.

Rahman L, Anwar R, Mose JC

Hypertension in pregnancy 2024; (43(1)):2405991 doi:10.1080/10641955.2024.2405991.

A Systematic Review of Complications Following Pre-eclampsia.

Montgomery KS, Hensley C, Winseman A, et al.

Maternal and child health journal 2024; (28(11)):1876-1885 doi:10.1007/s10995-024-03999-z.

Analysis of ICAM-1 rs3093030, VCAM-1 rs3783605, and E-Selectin rs1805193 Polymorphisms in African Women Living with HIV and Preeclampsia.

Sibiya S, Mlambo ZP, Mthembu MH, et al.

International journal of molecular sciences 2024; (25(19)) doi:10.3390/ijms251910860.

Gestational Hypertension: A Contemporary Review of Epidemiology, Pathophysiology, and Therapeutic Approaches.

Sunita , Kaushik R, Gaur PK, Verma KK

Current hypertension reviews 2024; (20(3)):117-126 doi:10.2174/0115734021312990241115045601.

Predictive performance of sFlt-1, PlGF and the sFlt-1/PlGF ratio for preeclampsia: A systematic review and meta-analysis.

Zhang L, Li W, Chi X, et al.

Journal of gynecology obstetrics and human reproduction 2025; (54(4)):102925 doi:10.1016/j.jogoh.2025.102925.

Placenta Accreta Spectrum Disorder Associated With Late Onset Pre-Eclampsia: A Case Report.

El Sayed S, Noel L, Lorquet S, Chantraine F

Clinical case reports 2025; (13(4)):e70346 doi:10.1002/ccr3.70346.

Association of severity features and laboratory biomarkers with adverse maternal outcomes in pre-eclamptic women: a retrospective cohort study in an Ethiopian tertiary hospital.

Abraha HE, Teka H

BMJ open 2025; (15(4)):e089935 doi:10.1136/bmjopen-2024-089935.

Clinical implications of a history of pre-eclampsia in women with type two diabetes mellitus.

Pearson MC, Wang H, Murdoch CE, Doney ASF

Diabetic medicine : a journal of the British Diabetic Association 2025; (42(6)):e70046 doi:10.1111/dme.70046.

Comparison of proteinuria assessment methods and their association with maternal-fetal outcomes in preeclampsia.

Sonkusare S, Prabhu L, Shetty P, et al.

European journal of obstetrics, gynecology, and reproductive biology 2025; (311()):114010 doi:10.1016/j.ejogrb.2025.114010.

Abbreviated 12-Hour Postpartum Magnesium Sulphate Therapy is Equally Effective and Safer Than Standard 24-Hour Therapy in Preeclampsia With Severe Features: Results From A Randomized Controlled Trial.

Saha PK, Sheokand S, Dhaliwal LK, et al.

Journal of family & reproductive health 2025; (19(1)):31-36 doi:10.18502/jfrh.v19i1.18437.

Long-Term Cardiovascular Risk and Maternal History of Pre-Eclampsia.

Palmiero P, Caretto P, Ciccone MM, et al.

Journal of clinical medicine 2025; (14(9)) doi:10.3390/jcm14093121.

Hypertensive disorder prediction among first-trimester antenatal patients using Gestosis score.

P Kundargi A, K Naagar J, Jain R, et al.

Bioinformation 2025; (21(4)):618-622 doi:10.6026/973206300210618.

Partner involvement and emotional and informational support gaps as predictors of postpartum birth trauma symptoms: a multi-center cross-sectional study of 230 women at 42 days postpartum.

Li L, Xiao L, Yuan X, et al.

BMC pregnancy and childbirth 2025; (25(1)):918 doi:10.1186/s12884-025-08084-z.

Large-Scale Proteomics Reveals New Candidate Biomarkers for Late-Onset Preeclampsia.

Andresen IJ, Romero R, Westerberg AC, et al.

Hypertension (Dallas, Tex. : 1979) 2025; doi:10.1161/HYPERTENSIONAHA.125.25189.

Perinatal outcomes in patients with preeclampsia and elevated sFlt-1/PlGF before term. A retrospective cohort study.

Linares S, Reyes O

European journal of obstetrics, gynecology, and reproductive biology 2025; (315()):114770 doi:10.1016/j.ejogrb.2025.114770.

Assessment of the Values of Endoglin and Soluble Fms-Like Tyrosine Kinase-1/Placental Growth Factor Ratio Among Women at Risk for Pre-eclampsia: A Cross-Sectional Study.

Subramaniam S, Mourouganandane P, T S M

Cureus 2025; (17(10)):e93723 doi:10.7759/cureus.93723.

The Role of Angiogenetic Factors in Preeclampsia.

Papapanagiotou A, Daskalaki MA, Gargalionis AN, et al.

International journal of molecular sciences 2025; (26(21)) doi:10.3390/ijms262110431.

Early initiation of low-dose aspirin for the prevention of pre-eclampsia in high-risk pregnancies.

Alsulami FT, Hamed EM

Scientific reports 2026; (16(1)):1761 doi:10.1038/s41598-025-28078-3.

Subtypes and onset of hypertensive disorders of pregnancy and cardiovascular disease within 5 years after delivery.

Hu H, Savitz DA, Shenkman EA

Frontiers in cardiovascular medicine 2026; (13()):1701507 doi:10.3389/fcvm.2026.1701507.