Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
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Centers for Disease Control and Prevention
Atlanta, United States
National Center for Emerging and Zoonotic Infectious Diseases
Atlanta, United States
Indian Health Service
Bethesda, United States
The University of Texas Medical Branch at Galveston
Galveston, United States
University of Maryland, Baltimore
Baltimore, United States
California Department of Public Health
Sacramento, United States
Office of Infectious Diseases
Atlanta, United States
Mayo Clinic in Arizona
Scottsdale, United States
Tianjin University
Tianjin, China
University of North Carolina at Chapel Hill
Chapel Hill, United States
References
References (46)
- 1
Recognition of and Prompt Treatment for Tick-Borne Infections in Children.
Mukkada S, Buckingham SC
Infectious disease clinics of North America 2015; (29(3)):539-55.
PMID: 26188606 - 2
Ongoing Cerebral Vasculitis During Treatment of Rocky Mountain Spotted Fever.
Sun LR, Huisman TA, Yeshokumar AK, Johnston MV
Pediatric neurology 2015; (53(5)):434-8.
PMID: 26294045 - 3
Diagnosis and Management of Tickborne Rickettsial Diseases: Rocky Mountain Spotted Fever and Other Spotted Fever Group Rickettsioses, Ehrlichioses, and Anaplasmosis - United States.
Biggs HM, Behravesh CB, Bradley KK, et al.
MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports 2016; (65(2)):1-44 doi:10.15585/mmwr.rr6502a1.
PMID: 27172113 - 4
[Rocky Mountain spotted fever in Mexican children: Clinical and mortality factors].
Álvarez-Hernández G, Candia-Plata Mdel C, Delgado-de la Mora J, et al.
Salud publica de Mexico 2016; (58(3)):385-92.
PMID: 27598937 - 5
[Complications and cause of death in mexican children with rocky mountain spotted fever].
Martínez-Medina MÁ, Rascón-Alcantar A
Gaceta medica de Mexico 2016; (152(6)):789-795.
PMID: 27861477 - 6
Retrospective Study of Rocky Mountain Spotted Fever in Children.
Tull R, Ahn C, Daniel A, et al.
Pediatric dermatology 2017; (34(2)):119-123 doi:10.1111/pde.13053.
PMID: 27990680 - 7
[Fatal case of rickettsiosis in a toddler from southeastern Mexico].
Lugo-Caballero C, Dzul-Rosado K, Rodríguez-Moreno G, et al.
Archivos argentinos de pediatria 2017; (115(1)):e5-e8 doi:10.5546/aap.2017.e5.
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An unusual case of sepsis and petechial rash.
Gardner C
JAAPA : official journal of the American Academy of Physician Assistants 2017; (30(5)):30-32 doi:10.1097/01.JAA.0000513349.15030.59.
PMID: 28441217 - 9
The Evaluation and Management of Rocky Mountain Spotted Fever in the Emergency Department: a Review of the Literature.
Gottlieb M, Long B, Koyfman A
The Journal of emergency medicine 2018; (55(1)):42-50 doi:10.1016/j.jemermed.2018.02.043.
PMID: 29685474 - 10
The Rickettsial Ankyrin Repeat Protein 2 Is a Type IV Secreted Effector That Associates with the Endoplasmic Reticulum.
Lehman SS, Noriea NF, Aistleitner K, et al.
mBio 2018; (9(3)) doi:10.1128/mBio.00975-18.
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Septic Shock Caused by Rocky Mountain Spotted Fever in a Suburban Texas Patient with Pet Dog Exposure: A Case Report.
Hatcher C, Karahalios B, Badam M
The American journal of case reports 2018; (19()):917-919 doi:10.12659/AJCR.909636.
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Intravenous Immunoglobulin Therapy for Cerebral Vasculitis Associated with Rocky Mountain Spotted Fever.
Allen HC, Welliver RC, Fogarty MW, et al.
Journal of pediatric intensive care 2017; (6(2)):142-144 doi:10.1055/s-0036-1587327.
PMID: 31073439 - 13
HLA-B27 spondyloarthritis and spotted fever rickettsiosis: case-based review.
Redford AH, Trost JR, Sibbitt WL, et al.
Rheumatology international 2019; (39(9)):1643-1650 doi:10.1007/s00296-019-04330-8.
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Reported County-Level Distribution of the American Dog Tick (Acari: Ixodidae) in the Contiguous United States.
Lehane A, Parise C, Evans C, et al.
Journal of medical entomology 2020; (57(1)):131-155 doi:10.1093/jme/tjz119.
PMID: 31368492 - 15
Selective fragmentation of the trans-Golgi apparatus by Rickettsia rickettsii.
Aistleitner K, Clark T, Dooley C, Hackstadt T
PLoS pathogens 2020; (16(5)):e1008582 doi:10.1371/journal.ppat.1008582.
PMID: 32421751 - 16
Brain Death Secondary to Rocky Mountain Spotted Fever Encephalitis.
Rhodes SD, Teagarden AM, Graner B, et al.
Case reports in critical care 2020; (2020()):5329420 doi:10.1155/2020/5329420.
PMID: 32426169 - 17
Epidemiology and Clinical Features of Rocky Mountain Spotted Fever from Enhanced Surveillance, Sonora, Mexico: 2015-2018.
Álvarez-López DI, Ochoa-Mora E, Nichols Heitman K, et al.
The American journal of tropical medicine and hygiene 2021; (104(1)):190-197.
PMID: 33146112 - 18
Isolation of Rickettsia rickettsii in Rocky Mountain Spotted Fever Outbreak, Panama.
Zaldívar Y, Hernández M, Domínguez L, et al.
Emerging infectious diseases 2021; (27(4)):1245-1247 doi:10.3201/eid2704.201606.
PMID: 33755006 - 19
Rocky Mountain Spotted Fever Masquerading as Gastroenteritis: A Common but Overlooked Clinical Presentation.
Braun DS, Greenberg I, Pagadala M
Cureus 2021; (13(4)):e14438 doi:10.7759/cureus.14438.
PMID: 34079651 - 20
Clinical features of patients with Rocky Mountain spotted fever, dengue and chikungunya infection.
Mora JD, Licona-Enríquez JD, Álvarez-López DI, et al.
Gaceta medica de Mexico 2021; (157(1)):58-63 doi:10.24875/GMM.20000105.
PMID: 34125821 - 21
Clinical characteristics of Rocky Mountain spotted fever in the United States: A literature review.
Jay R, Armstrong PA
Journal of vector borne diseases 2020; (57(2)):114-120 doi:10.4103/0972-9062.310863.
PMID: 34290155 - 22
Impact of a Severe Rocky Mountain Spotted Fever Case on Treatment Practices at an Academic Institution Within a Nonendemic Area.
Krawiec C, Ceneviva GD, Zhou S, Thomas NJ
Wilderness & environmental medicine 2021; (32(4)):427-432 doi:10.1016/j.wem.2021.05.005.
PMID: 34391635 - 23
Case Report: Rocky Mountain Spotted Fever with Adrenalectomy and a Hard-to-Find Tick.
Zhou C, Woods P, Abouzeid A, Brooks MN
The American journal of case reports 2022; (23()):e934505 doi:10.12659/AJCR.934505.
PMID: 35100242 - 24
Knowledge, Attitudes, and Practices on Rocky Mountain Spotted Fever among Physicians in a Highly Endemic Region-Mexicali, Mexico.
Bestul N, Padilla R, Montaño T, et al.
The American journal of tropical medicine and hygiene 2022; (107(4)):773-779 doi:10.4269/ajtmh.21-1017.
PMID: 35995132 - 25
A forty-year review of Rocky Mountain spotted fever cases in California shows clinical and epidemiologic changes.
Kjemtrup AM, Padgett K, Paddock CD, et al.
PLoS neglected tropical diseases 2022; (16(9)):e0010738 doi:10.1371/journal.pntd.0010738.
PMID: 36108065 - 26
Morbidity and Functional Outcomes Following Rocky Mountain Spotted Fever Hospitalization-Arizona, 2002-2017.
Drexler NA, Close R, Yaglom HD, et al.
Open forum infectious diseases 2022; (9(10)):ofac506 doi:10.1093/ofid/ofac506.
PMID: 36324320 - 27
Clinical manifestations of Rickettsia rickettsii in a familial outbreak in Panama.
Daza T CA, Estripeaut D, Morales MS, et al.
Travel medicine and infectious disease 2023; (52()):102542 doi:10.1016/j.tmaid.2023.102542.
PMID: 36646398 - 28
Serologic Testing for Rocky Mountain Spotted Fever in a Low-Incidence Region.
Wang J, Handel AS
Journal of the Pediatric Infectious Diseases Society 2023; (12(8)):445-450 doi:10.1093/jpids/piad051.
PMID: 37467350 - 29
Rocky Mountain Spotted Fever Associated With Cardiac Arrhythmias.
Syed Z, Scott C, Nguyen B, Phyu E
Cureus 2023; (15(7)):e42288 doi:10.7759/cureus.42288.
PMID: 37609088 - 30
POTENTIAL SHARED DISEASE RISK AMONG DOGS AND COYOTES (CANIS LATRANS) EXEMPLIFIED BY THE ECOLOGY OF RICKETTSIOSIS IN A ROCKY MOUNTAIN SPOTTED FEVER-EPIDEMIC REGION IN NORTHERN MEXICO.
Marcek J, Foley J, Backus L, et al.
Journal of wildlife diseases 2023; (59(4)):722-733 doi:10.7589/JWD-D-22-00179.
PMID: 37846906 - 31
Differences in the reproductive output and larval survival of Rocky Mountain wood ticks (Dermacentor andersoni) and American dog ticks (Dermacentor variabilis) from prairie populations near their northern distributional limits in western Canada.
Diyes CP, Dergousoff SJ, Chilton NB
Experimental & applied acarology 2023; (91(4)):645-660 doi:10.1007/s10493-023-00856-6.
PMID: 38015278 - 32
Empirical Administration of Doxycycline for Rocky Mountain Spotted Fever: A Case Report.
Dey P, Mitu MJ, Chakrabarty S, et al.
Cureus 2023; (15(10)):e47492 doi:10.7759/cureus.47492.
PMID: 38022143 - 33
Unconventional Rocky Mountain Spotted Fever Presentation From Kentucky: A Compelling Case Report and Literature Review.
Hussain A, Gray C, Marlowe S, et al.
Cureus 2023; (15(11)):e48558 doi:10.7759/cureus.48558.
PMID: 38074000 - 34
The emergence of Rocky Mountain spotted fever in the southwestern United States and northern Mexico requires a binational One Health approach.
Foley J, Álvarez-Hernández G, Backus LH, et al.
Journal of the American Veterinary Medical Association 2024; (262(5)):698-704 doi:10.2460/javma.23.07.0377.
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An Abnormal Presentation of Rocky Mountain Spotted Fever: A Case Report.
Nelson JJ, Buchmiller K, Valentine MJ, et al.
Cureus 2024; (16(3)):e57319 doi:10.7759/cureus.57319.
PMID: 38690503 - 36
Rocky Mountain Spotted Fever Mimicking Multisystem Inflammatory Syndrome in Hospitalized Children, Sonora, Mexico.
Álvarez-Hernández G, Rivera-Rosas CN, Calleja-López JRT, et al.
Emerging infectious diseases 2024; (30(7)):1463-1466 doi:10.3201/eid3007.240033.
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Rocky Mountain Spotted Fever Encephalitis and "Starry Sky" Pattern on MRI: A Case Report.
Mikhaiel JP, Parasram M, Park J, et al.
The neurologist 2025; (30(1)):34-38 doi:10.1097/NRL.0000000000000586.
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Rocky Mountain Spotted Fever in Children along the US‒Mexico Border, 2017-2023.
Chiang L, Ramchandar N, Aramkul J, et al.
Emerging infectious diseases 2024; (30(11)):2288-2293 doi:10.3201/eid3011.231760.
PMID: 39387516 - 39
A Comparison of the Clinical and Epidemiological Profile of Rocky Mountain Spotted Fever with Dengue and COVID-19 in Hospitalized Children, Sonora, México, 2015-2022.
Álvarez-Hernández G, Rivera-Rosas CN, Calleja-López JRT, et al.
Tropical medicine and infectious disease 2025; (10(1)) doi:10.3390/tropicalmed10010020.
PMID: 39852671 - 40
An Atypical Presentation of Rocky Mountain Spotted Fever Presenting as Progressive Vision Loss: A Case Report.
Abourahma H, Adas S, Salimi T, et al.
Cureus 2025; (17(5)):e83782 doi:10.7759/cureus.83782.
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Incidence and influencing factors of tooth discoloration in children using doxycycline: a meta-analysis.
Ma K, Lu M, Li H, et al.
Frontiers in pediatrics 2025; (13()):1644231 doi:10.3389/fped.2025.1644231.
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An effector of phosphatidylinositol 3-kinase activity promotes Rickettsia rickettsii virulence by enhancing autophagy.
Huang D, OuYang X, Peng Z, et al.
mBio 2025; (16(11)):e0228425 doi:10.1128/mbio.02284-25.
PMID: 40980887 - 43
Dental safety of short-term doxycycline use in children under 8 years: a systematic review and meta-analysis.
Rajan AS, Gopal M, Periyathambi M, Kuttiatt VS
Frontiers in pharmacology 2025; (16()):1646638 doi:10.3389/fphar.2025.1646638.
PMID: 41069592 - 44
Tickborne microorganisms in Dermacentor andersoni (Acari: Ixodidae) in the Bitterroot Mountains of Western Montana.
Clark KL, Nunez JV, Gentry C, et al.
Ticks and tick-borne diseases 2025; (16(6)):102555 doi:10.1016/j.ttbdis.2025.102555.
PMID: 41092714 - 45
Clinical Characterization and GIS-Based Surveillance of Pediatric Rocky Mountain Spotted Fever in Mexico: Identifying High-Burden Areas.
Concha-Mora LA, Mares-Gil JE, Guerrero-Gamiño I, et al.
Journal of the Pediatric Infectious Diseases Society 2025; doi:10.1093/jpids/piaf112.
PMID: 41408712 - 46
Predictors of Fatal Outcomes among Pediatric Patients Hospitalized for Rocky Mountain Spotted Fever, Sonora, Mexico, 2004-20241.
Bellman S, McCoy KD, Enriquez D, et al.
Emerging infectious diseases 2026; (32(2)):180-190 doi:10.3201/eid3202.251223.
PMID: 41714602