Research & Literature
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Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
Visualize citation networks across 130 referenced papers
Top Authors
- Dinesh Khanna University of Michigan
- Christopher P. Denton University College London
- Oliver Distler University Hospital of Zurich
- Yannick Allanore Hôpital Cochin
- Marco Matucci‐Cerinic Istituti di Ricovero e Cura a Carattere Scientifico
- Otylia Kowal‐Bielecka Medical University of Białystok
- Elizabeth R. Volkmann University of California, Los Angeles
- Daniel E. Furst Virginia Mason Medical Center
- Maurizio Cutolo University of Genoa
- Janet Pope Western University
Top Institutions
- University of California, Los Angeles Los Angeles, United States Elizabeth R. Volkmann , Donald P. Tashkin , Robert M. Elashoff , Jonathan Goldin , Nan W. Hultgren , Philip J. Clements , Suzanne Kafaja , Michael D. Roth , Grace Hyun J. Kim , Paula Carlson
- University of Michigan Ann Arbor, United States Dinesh Khanna , David Roofeh , Kevin R. Flaherty , Yen T. Chen , Swati Bhattacharyya , Andrew B. Shreiner , Jóhann E. Guðjónsson , Sara Jaafar , Justin M. Oldham , Feiyang Ma
- University College London London, United Kingdom Christopher P. Denton , Voon H Ong , Joseph Jacob , David Abraham , Edward P. Stern , Alan Holmes , Robert B. Good , Markella Ponticos , Nina Goldman , Alice Cole
- University Hospital of Zurich Zurich, Switzerland Oliver Distler , Anna‐Maria Hoffmann‐Vold , Cosimo Bruni , Wanlong Wu , Carina Mihai , Suzana Jordan , Alexandru Garaiman , Katharina Martini , Lisa Jungblut , Thi Dan Linh Nguyen‐Kim
- Hôpital Cochin Paris, France Yannick Allanore , Luc Mouthon , Paul Legendre , Clara Vigneron , Aëlle Le Gall , Clothilde Gros , André Kahan , Pascal Cohen , Jonathan London , Marion Casadevall
- Istituti di Ricovero e Cura a Carattere Scientifico Rome, Italy Marco Matucci‐Cerinic , Lorenzo Cavagna , Elena Raschi , Carlomaurizio Montecucco , Cecilia Beatrice Chighizola , Nicola Farina , María Orietta Borghi , Marta Colletti , Lucio Calandriello , Ludovico De Stefano
- University of California, San Francisco San Francisco, United States C. Correll , Mary Karin Connolly , Harold R. Collard , Richard K. Vehe , Monica Yang , Paul J. Wolters , C. Egla Rabinovich , Julie Morisset , Dvir Aran , Danielle R. Bullock
- Inserm Paris, France Alain Lescoat , Valérie Lecureur , A. Maria , Sébastien Sanges , Jean‐Luc Cracowski , Charles Khouri , Aurélien Chepy , Danièle Noël , Olivier Fardel , Nicolas Clere
- University of Florence Florence, Italy Mirko Manetti , Silvia Bellando-Randone , Eloisa Romano , Irene Rosa , Jelena Blagojević , Lidia Ibba‐Manneschi , Martina Orlandi , Bianca Saveria Fioretto , Susanna Cappelli , Cristina Scaletti
- University of Pittsburgh Pittsburgh, United States Robert Lafyatis , Kathryn S. Torok , Robyn T. Domsic , Thomas A. Medsger , Patrizia Fuschiotti , Amr H. Sawalha , Eleanor Valenzi , Tracy Tabib , Christina Morse , Anastasia Gorelova
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Risk factors and outcome of Thai patients with scleroderma renal crisis: a disease duration-matched case control study.
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Risk Factors for Future Scleroderma Renal Crisis at Systemic Sclerosis Diagnosis.
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The Journal of rheumatology 2019; (46(1)):85-92 doi:10.3899/jrheum.171186.
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Clinical significance of autoantibodies in dermatomyositis and systemic sclerosis.
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EndMT: A promising and controversial field.
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ANCA-Associated Vasculitis Co-Occurrence With Systemic Sclerosis: A Case Report of a Rare Diagnostic Dilemma.
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B-type Natriuretic Peptide as a Marker of Different Forms of Systemic Sclerosis.
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Minimal Clinically Important Differences for the Modified Rodnan Skin Score: Results from the Scleroderma Lung Studies (SLS-I and SLS-II).
Khanna D, Clements PJ, Volkmann ER, et al.
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The impact of gastroesophageal reflux disease symptoms in scleroderma: effects on sleep quality.
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Diffused Alveolar Hemorrhage in the Setting of Scleroderma Renal Crisis.
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Mortality and hospitalization outcomes of interstitial lung disease and pulmonary hypertension in the Singapore systemic sclerosis cohort.
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Interstitial Lung Disease in Systemic Sclerosis: Focus on Early Detection and Intervention.
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Serodiscordant patients with systemic sclerosis: when antibody does not correspond to skin involvement.
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Morphea: a practical review of its diagnosis, classification and treatment.
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Nailfold Videocapillaroscopy as a Candidate Biomarker for Organ Involvement and Prognosis in Patients with Systemic Sclerosis.
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ACE inhibitors in SSc patients display a risk factor for scleroderma renal crisis-a EUSTAR analysis.
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Clinical course of Japanese patients with early systemic sclerosis: A multicenter, prospective, observational study.
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Update on Management of Morphea (Localized Scleroderma) in Children.
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Renal Involvement in Systemic Sclerosis: An Update.
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Performance Characteristics of Pulmonary Function Tests for the Detection of Interstitial Lung Disease in Adults With Early Diffuse Cutaneous Systemic Sclerosis.
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Reduced ventilatory efficiency during exercise predicts major vascular complications and mortality for interstitial lung disease in systemic sclerosis.
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Tocilizumab in systemic sclerosis: a randomised, double-blind, placebo-controlled, phase 3 trial.
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Differentiating Delayed Esophageal Clearance From Reflux in Scleroderma.
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Clinical Treatment Options in Scleroderma: Recommendations and Comprehensive Review.
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Autologous stem cell transplantation in scleroderma.
Farge D, Ait Abdallah N, Marjanovic Z, Del Papa N
Presse medicale (Paris, France : 1983) 2021; (50(1)):104065 doi:10.1016/j.lpm.2021.104065.
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Scleroderma renal crisis.
Hudson M, Ghossein C, Steen V
Presse medicale (Paris, France : 1983) 2021; (50(1)):104063 doi:10.1016/j.lpm.2021.104063.
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Recurrent Plaque Morphea Successfully Treated with PDO Mono Threads and Topical Tacrolimus Ointment.
Sakhiya J, Sakhiya D, Dedakiya A, et al.
The Journal of clinical and aesthetic dermatology 2020; (13(10)):38-41.
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Nailfold capillaroscopy in systemic diseases: short overview for internal medicine.
Dima A, Berza I, Popescu DN, Parvu MI
Romanian journal of internal medicine = Revue roumaine de medecine interne 2021; (59(3)):201-217 doi:10.2478/rjim-2021-0007.
PMID: 33600677 - 55
Treatment for systemic sclerosis-associated interstitial lung disease.
Roofeh D, Lescoat A, Khanna D
Current opinion in rheumatology 2021; (33(3)):240-248 doi:10.1097/BOR.0000000000000795.
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Systemic Sclerosis and Pulmonary Disease.
Ngo K
Advances in experimental medicine and biology 2021; (1303()):173-182 doi:10.1007/978-3-030-63046-1_10.
PMID: 33788193 - 57
Systemic sclerosis (scleroderma): remaining challenges.
Connolly MK
Annals of translational medicine 2021; (9(5)):438 doi:10.21037/atm-20-5449.
PMID: 33842659 - 58
New promising drugs for the treatment of systemic sclerosis: pathogenic considerations, enhanced classifications, and personalized medicine.
Lescoat A, Varga J, Matucci-Cerinic M, Khanna D
Expert opinion on investigational drugs 2021; (30(6)):635-652 doi:10.1080/13543784.2021.1923693.
PMID: 33909517 - 59
The Relationship between Pulmonary Damage and Peripheral Vascular Manifestations in Systemic Sclerosis Patients.
Ruaro B, Confalonieri M, Salton F, et al.
Pharmaceuticals (Basel, Switzerland) 2021; (14(5)) doi:10.3390/ph14050403.
PMID: 33922710 - 60
Circulating Galectin-1 and Galectin-3 in Sera From Patients With Systemic Sclerosis: Associations With Clinical Features and Treatment.
Sundblad V, Gomez RA, Stupirski JC, et al.
Frontiers in pharmacology 2021; (12()):650605 doi:10.3389/fphar.2021.650605.
PMID: 33959016 - 61
A mixed method study exploring patient satisfaction and feasibility of two exercise programmes in systemic sclerosis-associated microstomia.
Sydow E, Van der Elst K, Verschueren P, et al.
Rheumatology advances in practice 2021; (5(2)):rkab017 doi:10.1093/rap/rkab017.
PMID: 34013159 - 62
The Efficacy of a Home-Based, Self-Administered Hand Exercise Program for Patients With Systemic Sclerosis: A Randomized Controlled, Evaluator-Blind, Clinical Trial.
Gokcen N, Badak SO, Sarpel T, et al.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 2022; (28(2)):e422-e429 doi:10.1097/RHU.0000000000001752.
PMID: 34030163 - 63
Emerging treatments for scleroderma/systemic sclerosis.
Zhu JL, Black SM, Chen HW, Jacobe HT
Faculty reviews 2021; (10()):43 doi:10.12703/r/10-43.
PMID: 34131653 - 64
New Insights into Profibrotic Myofibroblast Formation in Systemic Sclerosis: When the Vascular Wall Becomes the Enemy.
Romano E, Rosa I, Fioretto BS, et al.
Life (Basel, Switzerland) 2021; (11(7)) doi:10.3390/life11070610.
PMID: 34202703 - 65
Clinical trial protocol: PRednisolone in early diffuse cutaneous Systemic Sclerosis (PRedSS).
Herrick AL, Griffiths-Jones DJ, Ryder WD, et al.
Journal of scleroderma and related disorders 2021; (6(2)):146-153 doi:10.1177/2397198320957552.
PMID: 34222671 - 66
Upcoming treatments for morphea.
Wenzel D, Haddadi NS, Afshari K, et al.
Immunity, inflammation and disease 2021; (9(4)):1101-1145 doi:10.1002/iid3.475.
PMID: 34272836 - 67
Esophageal manifestation in patients with scleroderma.
Voulgaris TA, Karamanolis GP
World journal of clinical cases 2021; (9(20)):5408-5419 doi:10.12998/wjcc.v9.i20.5408.
PMID: 34307594 - 68
Considerations for a combined index for limited cutaneous systemic sclerosis to support drug development and improve outcomes.
Lescoat A, Murphy SL, Roofeh D, et al.
Journal of scleroderma and related disorders 2021; (6(1)):66-76 doi:10.1177/2397198320961967.
PMID: 34316516 - 69
Therapeutic Approaches to Systemic Sclerosis: Recent Approvals and Future Candidate Therapies.
Lescoat A, Roofeh D, Kuwana M, et al.
Clinical reviews in allergy & immunology 2023; (64(3)):239-261 doi:10.1007/s12016-021-08891-0.
PMID: 34468946 - 70
Regulation of Partial and Reversible Endothelial-to-Mesenchymal Transition in Angiogenesis.
Fang JS, Hultgren NW, Hughes CCW
Frontiers in cell and developmental biology 2021; (9()):702021 doi:10.3389/fcell.2021.702021.
PMID: 34692672 - 71
High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients.
Ruaro B, Baratella E, Confalonieri P, et al.
Diagnostics (Basel, Switzerland) 2021; (11(11)) doi:10.3390/diagnostics11111960.
PMID: 34829307 - 72
Management of pregnancy with diffuse cutaneous systemic sclerosis: a case report and literature review.
Yang L, Sun W, Yao Q
The Journal of international medical research 2021; (49(11)):3000605211060160 doi:10.1177/03000605211060160.
PMID: 34851779 - 73
Clinical features and prognostic factors of systemic sclerosis in Guangxi, China: Retrospective, single-center study of long-term survival in 470 patients.
Chen J, Yang C, Pan J, et al.
International journal of rheumatic diseases 2022; (25(2)):182-191 doi:10.1111/1756-185X.14261.
PMID: 34889515 - 74
Safety and efficacy of abatacept in early diffuse cutaneous systemic sclerosis (ASSET): open-label extension of a phase 2, double-blind randomised trial.
Chung L, Spino C, McLain R, et al.
The Lancet. Rheumatology 2020; (2(12)):e743-e753 doi:10.1016/S2665-9913(20)30237-X.
PMID: 34966900 - 75
NADPH-derived ROS generation drives fibrosis and endothelial-to-mesenchymal transition in systemic sclerosis: Potential cross talk with circulating miRNAs.
Posadino AM, Erre GL, Cossu A, et al.
Biomolecular concepts 2022; (13(1)):11-24 doi:10.1515/bmc-2021-0023.
PMID: 35189048 - 76
Chronic dyspnea with Raynaud's phenomenon and elevated ANA: A diagnosis of systemic sclerosis sine scleroderma.
Chong WH, Saha BK, Beegle S
The American journal of the medical sciences 2023; (365(2)):198-204 doi:10.1016/j.amjms.2022.01.023.
PMID: 35276077 - 77
Antinuclear antibody pattern and autoantibody profiling of systemic sclerosis patients in a tertiary referral center in North India.
Machhua S, Sharma SK, Kumar Y, et al.
Pathology international 2022; (72(5)):283-292 doi:10.1111/pin.13221.
PMID: 35319814 - 78
Anti-RNA polymerase III antibodies in patients with suspected and definite systemic sclerosis: Why and how to screen.
Lazzaroni MG, Airò P
Journal of scleroderma and related disorders 2018; (3(3)):214-220 doi:10.1177/2397198318786158.
PMID: 35382018 - 79
Patient perception of disease burden in diffuse cutaneous systemic sclerosis.
Khanna D, Allanore Y, Denton CP, et al.
Journal of scleroderma and related disorders 2020; (5(1)):66-76 doi:10.1177/2397198319866615.
PMID: 35382406 - 80
Assessment of skin disease in scleroderma: Practices and opinions of investigators studying scleroderma.
Showalter K, Merkel PA, Khanna D, Gordon JK
Journal of scleroderma and related disorders 2020; (5(3)):167-171 doi:10.1177/2397198320921044.
PMID: 35382518 - 81
High D-dimer plasma concentration in systemic sclerosis patients: Prevalence and association with vascular complications.
Furtado S, Dunogué B, Jourdi G, et al.
Journal of scleroderma and related disorders 2021; (6(2)):178-186 doi:10.1177/2397198320957558.
PMID: 35386738 - 82
Immunosuppression use in early systemic sclerosis may be increasing over time.
Park R, Nevskaya T, Baron M, Pope JE
Journal of scleroderma and related disorders 2022; (7(1)):33-41 doi:10.1177/23971983211000971.
PMID: 35386940 - 83
Nailfold capillaroscopy for the early diagnosis of the scleroderma spectrum of diseases in patients without Raynaud's phenomenon.
Hong C, Xiang L, Saffari SE, Low AH
Journal of scleroderma and related disorders 2022; (7(2)):144-150 doi:10.1177/23971983221088460.
PMID: 35585956 - 84
Autoantibodies versus Skin Fibrosis Extent in Systemic Sclerosis: A Case-Control Study of Inverted Phenotypes.
Tieu A, Chaigne B, Dunogué B, et al.
Diagnostics (Basel, Switzerland) 2022; (12(5)) doi:10.3390/diagnostics12051067.
PMID: 35626223 - 85
Systemic Sclerosis, Malnutrition, and Small Bowel Obstruction: Why Clinicians Should Consider Early Total Parenteral Nutrition in Systemic Sclerosis With Severe Gastrointestinal Involvement.
Massat B, McCarthy J
Cureus 2022; (14(8)):e27638 doi:10.7759/cureus.27638.
PMID: 36072159 - 86
Insights into molecular and clinical characteristics of very early systemic sclerosis.
Bellando-Randone S, Del Galdo F, Matucci-Cerinic M
Current opinion in rheumatology 2022; (34(6)):351-356 doi:10.1097/BOR.0000000000000903.
PMID: 36082752 - 87
Effectiveness of PUVA vs. UVA1 phototherapy in the treatment of morphea patients.
Malewska-Woźniak A, Osmola-Mañkowska A, Adamski Z
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