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Can You Get Ramsay Hunt Syndrome Twice? Recurrence Risk

At a Glance

Ramsay Hunt syndrome can happen twice, but recurrence is uncommon and its exact likelihood is unknown. After the rash and fever resolve, Shingrix lowers the risk of future shingles, although it cannot guarantee prevention. New facial weakness or an ear rash needs urgent medical evaluation.

Yes, it is technically possible to get Ramsay Hunt syndrome (RHS) more than once, but it is uncommon [1]. Patients who have had RHS often fear a recurrence, but research indicates the chances are low. Getting the shingles vaccine can lower the risk of the virus reactivating again [2].

The Likelihood of Recurrence

Ramsay Hunt syndrome is a specific form of shingles (herpes zoster) that occurs when the varicella-zoster virus—the same virus that causes chickenpox—reactivates in a nerve cluster near the ear [3][4]. This reactivation often causes a painful rash on or inside the ear, along with one-sided facial paralysis and sometimes hearing or balance issues. While the virus remains dormant in your body even after you recover, it rarely wakes up in the same way a second time.

RHS-specific recurrence is uncommon, though its exact frequency and timing are not well established. A study following patients with various types of facial nerve palsy (including both Bell’s palsy and RHS) found that recurrent events occurred in about 6.8% of patients [1]. There are also rare medical case reports of patients developing RHS twice or experiencing symptoms on both sides of their face sequentially [5][6]. Because an exact percentage for RHS alone is not known, it is impossible to predict an individual’s exact risk, but it remains a rare event.

Because RHS is a manifestation of a shingles outbreak [3][7], taking steps to lower your risk of shingles will also help protect against a second episode of RHS.

The Role of the Shingles Vaccine

Getting vaccinated is recommended to lower the risk of a future shingles outbreak [2]. The recombinant zoster vaccine (commonly known by the brand name Shingrix) helps prevent the varicella-zoster virus from reactivating.

In a large clinical trial of adults who had previously recovered from an episode of shingles, no recurrent cases were observed in the vaccinated group during the follow-up period, while recurrences did occur in the unvaccinated placebo group [2]. While this shows the vaccine substantially reduces the risk, it does not guarantee 100% protection, and breakthrough cases can still occur.

The trial also demonstrated that having a prior shingles infection does not prevent your immune system from mounting a strong, protective response to the vaccine [8][2]. Because Shingrix is a non-live vaccine, it is generally recommended even for individuals whose immune systems are compromised [9][10]. However, you should still check with your doctor for individual contraindications, such as a severe allergy to a vaccine component.

When Should You Get Vaccinated?

If you have just recovered from Ramsay Hunt syndrome, you might be eager to get the vaccine. In the United States, the Centers for Disease Control and Prevention (CDC) recommends the two-dose Shingrix vaccine (usually given 2 to 6 months apart) for:

  • Adults aged 50 and older [9][11].
  • Adults aged 19 and older who have weakened immune systems due to disease or therapy [9][12].

There is no strict, mandatory waiting period (such as waiting six months or a year) required by CDC guidelines before you can receive the vaccine after an outbreak [11][9]. Vaccination is generally deferred during active shingles or a significant acute illness. Once the acute illness has resolved—meaning the blisters have cleared and you no longer have a fever—the vaccine can usually be scheduled [2][9]. Residual nerve symptoms and the completion of antiviral medications do not, by themselves, require waiting to get vaccinated.

Lingering Symptoms vs. New Outbreaks

It is completely normal to have lingering symptoms like facial weakness, hearing changes, or nerve pain long after the acute infection has passed [13][14]. These persistent symptoms often reflect lingering nerve injury from the initial attack, rather than a sign of active viral infection, and they should not prevent you from getting the vaccine [15]. Note that the vaccine helps prevent future outbreaks, but it does not treat current RHS or repair existing nerve damage.

When to Seek Immediate Care

Do not self-diagnose persistent or worsening symptoms. If you experience new or worsening symptoms—such as a new one-sided facial weakness, a new blistering rash in or around the ear or mouth, severe ear pain, new hearing loss, vertigo, or trouble closing your eye—seek urgent medical evaluation. Early assessment and treatment are critical for protecting your facial nerve and hearing [16][17].

(Note: Sudden facial weakness accompanied by arm or leg weakness, speech difficulty, or severe headache requires emergency evaluation for a possible stroke [18]).

Common questions in this guide

What are the chances that Ramsay Hunt syndrome will come back?
Ramsay Hunt syndrome can recur, but a second episode is uncommon. The exact recurrence rate for Ramsay Hunt syndrome is not known; studies combining it with other facial nerve palsies and rare case reports show that recurrence is possible but difficult to predict.
Can Shingrix prevent another episode of Ramsay Hunt syndrome?
Shingrix lowers the risk of shingles caused by reactivation of the chickenpox virus, so it may also reduce the chance of another Ramsay Hunt episode. It is not 100% effective, and breakthrough cases can still occur.
When can I receive Shingrix after recovering from Ramsay Hunt syndrome?
CDC guidance does not require a fixed six-month or one-year wait. Vaccination is usually deferred while shingles is active or you have a significant acute illness, then can be scheduled after the rash clears and fever resolves; lingering nerve symptoms or finishing antiviral medicine alone do not require a delay.
Who is advised to get the shingles vaccine after Ramsay Hunt syndrome?
In the United States, the two-dose vaccine is recommended for adults 50 and older and for adults 19 and older with weakened immune systems because of disease or treatment. Doses are usually given 2 to 6 months apart, but a clinician should confirm the timing and any contraindications for you.
How do I know if symptoms are lingering or a new Ramsay Hunt outbreak?
Facial weakness, hearing changes, or nerve pain that persist after the original illness may reflect nerve injury rather than a new outbreak. New or worsening facial weakness, a blistering rash near the ear or mouth, severe ear pain, hearing loss, vertigo, or trouble closing the eye needs urgent medical evaluation.
When does facial weakness require emergency care?
Sudden facial weakness with arm or leg weakness, trouble speaking, or a severe headache can signal a stroke and requires emergency care. Even without those signs, new facial weakness or an ear rash should be assessed urgently because early treatment can help protect the facial nerve and hearing.

Questions to Ask Your Doctor

Curated prompts to bring to your next appointment.

  1. 1.Am I eligible for the Shingrix vaccine based on my age and immune status to help prevent another shingles outbreak?
  2. 2.How soon after my acute symptoms (like the rash and fever) clear can we schedule my first vaccine dose?
  3. 3.What is the recommended timeline for my second dose of the vaccine?
  4. 4.I take medications that affect my immune system; how does this impact when I should get the vaccine?
  5. 5.If I develop new facial weakness or a new ear rash, what is the best way to contact you for an urgent evaluation?

Questions For You

Tap a prompt to share your answer — we'll use it plus this page's context to start a tailored conversation.

References

References (18)
  1. 1

    Recurrent and Bilateral Facial Palsy in Bell's Palsy and Ramsay-Hunt Syndrome: Risk Factors and Clinical Outcomes.

    Johansen CF, Bhatia SS, Patel DR, et al.

    Plastic and reconstructive surgery 2026; doi:10.1097/PRS.0000000000013182.

    PMID: 42133713
  2. 2

    Herpes zoster recurrence, and safety and immunogenicity of the recombinant zoster vaccine in adults aged ≥50 years with a history of herpes zoster: A phase 3, randomized controlled trial.

    Jegede B, Zhou Y, Hawksworth H, et al.

    The Journal of infection 2025; (91(3)):106573 doi:10.1016/j.jinf.2025.106573.

    PMID: 40780591
  3. 3

    Ramsay Hunt syndrome.

    Jeon Y, Lee H

    Journal of dental anesthesia and pain medicine 2018; (18(6)):333-337 doi:10.17245/jdapm.2018.18.6.333.

    PMID: 30637343
  4. 4

    Brainstem and Cerebellar Involvement in Ramsay Hunt Syndrome.

    Letchuman V, Donohoe CD

    Case reports in otolaryngology 2019; (2019()):7605056 doi:10.1155/2019/7605056.

    PMID: 31915561
  5. 5

    Bilateral sequential Ramsay Hunt syndrome in an immunocompromised adult: a rare entity.

    Sheik-Ali S, Jiang Y, Nasef H, et al.

    Annals of the Royal College of Surgeons of England 2024; (106(2)):197-199 doi:10.1308/rcsann.2022.0133.

    PMID: 36448928
  6. 6

    Bilateral asymmetrical herpes-zoster with Ramsay hunt syndrome in an immunocompetent adult.

    Dai S, Huang X, Chen Y, et al.

    Virology journal 2020; (17(1)):123 doi:10.1186/s12985-020-01392-0.

    PMID: 32799908
  7. 7

    Zoster Cranial Polyneuropathy in a COVID-19 Patient.

    Antonescu F, Butnariu I, Cojocaru FM, et al.

    The American journal of case reports 2021; (22()):e934658 doi:10.12659/AJCR.934658.

    PMID: 34788266
  8. 8

    Immunogenicity of Recombinant Zoster Vaccine: A Systematic Review, Meta-Analysis, and Meta-Regression.

    Losa L, Antonazzo IC, Di Martino G, et al.

    Vaccines 2024; (12(5)) doi:10.3390/vaccines12050527.

    PMID: 38793778
  9. 9

    Use of Recombinant Zoster Vaccine in Immunocompromised Adults Aged ≥19 Years: Recommendations of the Advisory Committee on Immunization Practices - United States, 2022.

    Anderson TC, Masters NB, Guo A, et al.

    MMWR. Morbidity and mortality weekly report 2022; (71(3)):80-84 doi:10.15585/mmwr.mm7103a2.

    PMID: 35051134
  10. 10

    Herpes Zoster Vaccines.

    Harbecke R, Cohen JI, Oxman MN

    The Journal of infectious diseases 2021; (224(12 Suppl 2)):S429-S442 doi:10.1093/infdis/jiab387.

    PMID: 34590136
  11. 11

    Recommendations of the Advisory Committee on Immunization Practices for Use of Herpes Zoster Vaccines.

    Dooling KL, Guo A, Patel M, et al.

    MMWR. Morbidity and mortality weekly report 2018; (67(3)):103-108 doi:10.15585/mmwr.mm6703a5.

    PMID: 29370152
  12. 12

    Knowledge, Attitudes, and Practices Regarding Herpes Zoster Vaccination Among Specialists.

    Singer D, Sweeney C, Stempniewicz N, et al.

    Population health management 2024; (27(4)):231-240 doi:10.1089/pop.2023.0284.

    PMID: 38838030
  13. 13

    Herpes zoster oticus.

    Jahr SH, Wahl MS, Majid B, Samuelsen E

    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 2021; (141(2021-15)) doi:10.4045/tidsskr.21.0036.

    PMID: 34726042
  14. 14

    A case report of refractory otalgia after Ramsay Hunt syndrome successfully treated by applying pulsed radiofrequency to the great auricular nerve: A CARE-compliant article.

    Kim YS, Son JS, Lee H, Doo AR

    Medicine 2021; (100(39)):e27285 doi:10.1097/MD.0000000000027285.

    PMID: 34596124
  15. 15

    Ramsay Hunt syndrome: long-term facial palsy outcome assessed face-to-face by three different grading scales and compared to patient self-assessment.

    Kanerva M, Jones S, Pitkaranta A

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2021; (278(6)):1781-1787 doi:10.1007/s00405-020-06251-w.

    PMID: 32748187
  16. 16

    Ramsay Hunt syndrome: characteristics and patient self-assessed long-term facial palsy outcome.

    Kanerva M, Jones S, Pitkaranta A

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2020; (277(4)):1235-1245 doi:10.1007/s00405-020-05817-y.

    PMID: 31982948
  17. 17

    Herpes Zoster Oticus: Systematic Review of Clinical Prognostic Factors.

    Cassettari AJ, Silva VAR, Crespo AN

    International archives of otorhinolaryngology 2026; (30(1)):1-9 doi:10.1055/s-0045-1810000.

    PMID: 41821953
  18. 18

    Ramsay Hunt Syndrome With Multiple Cranial Neuropathies, Meningitis, and Subsequent Brainstem Encephalitis: A Case Report.

    Kawamoto S, Yoshinaga K, Watanabe R, Hirano T

    Cureus 2024; (16(11)):e73861 doi:10.7759/cureus.73861.

    PMID: 39691149

This page is for informational purposes only and does not constitute medical advice. Ask a healthcare professional about Shingrix timing and seek urgent care for new facial weakness, an ear rash, hearing loss, or vertigo.

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