Skip to content
PubMed This is a summary of 11 peer-reviewed journal articles Updated
Pulmonology

Why Is It Important to Use a Spacer With an Asthma Inhaler?

At a Glance

For a pressurized spray asthma inhaler, a spacer slows the medicine and separates pressing the canister from breathing, helping more medicine reach the lungs and reducing medicine left in the mouth and throat. It is not used with dry powder inhalers.

It can feel frustrating to carry around a bulky spacer. If your inhaler is a pressurized metered-dose inhaler (pMDI), a spacer is often recommended because it makes it easier to get medication into your lungs [1]. However, a spacer is not strictly mandatory for every single dose if you have been taught effective technique—and you should never delay using a rescue reliever inhaler during a sudden asthma attack just because you cannot find your spacer. But using one regularly, especially for daily controller medications, can help you get more consistent results from your inhaler [2].

How Your Inhaler Works: Spray vs. Powder

Not all asthma inhalers are the same, and understanding your specific device is important.

  • Pressurized Metered-Dose Inhalers (pMDIs): These are the classic aerosol spray inhalers. When you press down, they fire a fast-moving, pressurized plume of medication [3]. If you do not perfectly time your breath with the spray, much of the drug can crash into the back of your mouth or throat instead of traveling down your airways [3][4]. (Note: Some modern devices are breath-actuated or “soft-mist” inhalers and have different instructions).
  • Dry Powder Inhalers (DPIs): These deliver a dry powder rather than a liquid spray [5]. Because your own breath pulls the medication out of the device, you do not need to coordinate pressing a button. However, they require a quick, deep, and forceful inhalation, and you must be careful not to exhale into the device [6]. You do not use a spacer with a dry powder inhaler. Because not everyone can inhale forcefully enough, DPIs are not an automatic alternative for everyone.

The Benefits of Slowing Things Down

If you use a pMDI, a spacer—often called a “valved holding chamber” if it includes a one-way valve—serves two valuable functions:

1. Helping medication reach your lungs
A spacer acts as a holding reservoir [1]. By firing the medication into the chamber first, the spray slows down. This gives some of the larger droplets time to settle, leaving a fine mist suspended in the tube [7]. This separates the act of pressing the canister from the act of breathing, allowing you to inhale slowly and deeply, which can improve the amount of medication that reaches your lower airways [1][2].

2. Reducing side effects in your mouth and throat
Because the spacer catches larger droplets, less medication is left sitting on your throat [7][8]. For inhaled corticosteroids (preventative asthma medication), this is particularly helpful in reducing local side effects like throat irritation, hoarseness, and a fungal infection called oral thrush [1][8]. Note: A spacer reduces these risks but does not eliminate them. Always rinse your mouth, gargle, and spit out the water after using an inhaled corticosteroid.

Getting the Most Out of Your Spacer

To use your spacer safely and effectively:

  • Check compatibility: Spacers are not universally interchangeable, but you do not necessarily need a brand-name match. Check with your pharmacist or clinician to ensure the chamber you have fits your specific inhaler [8][9]. Do not switch inhaler types without talking to your prescriber.
  • Step-by-step technique: Shake the inhaler as directed, attach the spacer, and breathe out away from the device [10]. Press the canister for exactly one puff, then inhale promptly with a slow, steady breath. Hold your breath for 5 to 10 seconds if you are able, then breathe out [11]. If you need a second puff, wait the recommended time and repeat the process.
  • Follow cleaning instructions: Wash your spacer as directed by the manufacturer and let it air dry. Rubbing plastic chambers with a towel can create static electricity inside, which can cause the medication to stick to the walls instead of reaching your lungs [8].

Common questions in this guide

Why should I use a spacer with my asthma inhaler?
With a pressurized spray inhaler, a spacer slows the medication and separates pressing the canister from breathing in. This can make it easier to inhale slowly and help more medicine reach your lungs consistently.
Do I need a spacer with every type of asthma inhaler?
No. Spacers are used with pressurized metered-dose spray inhalers, but they are not used with dry powder inhalers. Breath-actuated and soft-mist inhalers may have different instructions, so ask your pharmacist or clinician which device is right for your inhaler.
Can a spacer prevent hoarseness or oral thrush?
A spacer can reduce how much inhaled corticosteroid remains in your mouth and throat, which may lower the risk of irritation, hoarseness, and oral thrush. It does not eliminate these problems, so rinse, gargle, and spit after using an inhaled corticosteroid.
What should I do if I have an asthma attack and do not have my spacer?
Do not delay using your rescue reliever inhaler just because you cannot find your spacer. Use the inhaler according to your asthma action plan and seek urgent help if your symptoms are severe or do not improve as directed.
How do I use and clean an asthma spacer correctly?
Shake the inhaler as directed, attach the spacer, breathe out away from it, and press only one puff before inhaling slowly and steadily. Hold your breath for 5 to 10 seconds if you can, wait as instructed before another puff, and wash the spacer according to the manufacturer’s directions before letting it air-dry.

Get notified when new evidence is published on asthma.

We monitor PubMed for new peer-reviewed studies on this topic and email a short summary when something meaningful changes.

References

References (11)
  1. 1

    Spacers and Valved Holding Chambers-The Risk of Switching to Different Chambers.

    Lavorini F, Barreto C, van Boven JFM, et al.

    The journal of allergy and clinical immunology. In practice 2020; (8(5)):1569-1573 doi:10.1016/j.jaip.2019.12.035.

    PMID: 31927099
  2. 2

    Balancing efficacy and portability: comparative in vitro/in vivo evaluation of MDI PLUS® versus AeroChamber2go™ spacers for aerosol delivery.

    Sobh AHM, Mohsen M, Abdelfattah AM, et al.

    The Journal of asthma : official journal of the Association for the Care of Asthma 2025; (62(12)):2054-2059 doi:10.1080/02770903.2025.2552742.

    PMID: 40888649
  3. 3

    Effect of MDI Actuation Timing on Inhalation Dosimetry in a Human Respiratory Tract Model.

    Talaat M, Si X, Xi J

    Pharmaceuticals (Basel, Switzerland) 2022; (15(1)) doi:10.3390/ph15010061.

    PMID: 35056118
  4. 4

    Effect of delayed pMDI actuation on the lung deposition of a fixed-dose combination aerosol drug.

    Farkas Á, Horváth A, Kerekes A, et al.

    International journal of pharmaceutics 2018; (547(1-2)):480-488 doi:10.1016/j.ijpharm.2018.06.016.

    PMID: 29886099
  5. 5

    Inhalation therapy devices for the treatment of obstructive lung diseases: the history of inhalers towards the ideal inhaler.

    Sorino C, Negri S, Spanevello A, et al.

    European journal of internal medicine 2020; (75()):15-18 doi:10.1016/j.ejim.2020.02.023.

    PMID: 32113944
  6. 6

    The dry powder inhaler features of the Easyhaler that benefit the management of patients.

    Chrystyn H, Lavorini F

    Expert review of respiratory medicine 2020; (14(4)):345-351 doi:10.1080/17476348.2020.1721286.

    PMID: 32013627
  7. 7

    In vitro characterisation of fluticasone propionate and ciclesonide delivered with and without valved holding chambers using cascade impaction and an adult simulated breathing profile.

    Csonka LL, Lehtimäki L, Csonka P

    BMJ open respiratory research 2026; (13(1)) doi:10.1136/bmjresp-2025-003963.

    PMID: 41985982
  8. 8

    Optimizing the Delivery of Inhaled Medication for Respiratory Patients: The Role of Valved Holding Chambers.

    McIvor RA, Devlin HM, Kaplan A

    Canadian respiratory journal 2018; (2018()):5076259 doi:10.1155/2018/5076259.

    PMID: 29849831
  9. 9

    Spacers and Valved Holding Chambers.

    Devadason S

    Journal of aerosol medicine and pulmonary drug delivery 2025; (38(4)):211-215 doi:10.1089/jamp.2025.87987.sd.

    PMID: 40772815
  10. 10

    Variability in Delivered Dose from Pressurized Metered-Dose Inhaler Formulations Due to a Delay Between Shake and Fire.

    Hatley RH, Parker J, Pritchard JN, von Hollen D

    Journal of aerosol medicine and pulmonary drug delivery 2017; (30(1)):71-79 doi:10.1089/jamp.2015.1284.

    PMID: 27635793
  11. 11

    The Relationship Between Clinical Trial Participation and Inhaler Technique Errors in Asthma and COPD Patients.

    Perumal R, Leite M, van Zyl-Smit RN

    International journal of chronic obstructive pulmonary disease 2020; (15()):1217-1224 doi:10.2147/COPD.S249620.

    PMID: 32581528

This page is for informational purposes only and does not replace medical advice about using an asthma inhaler or spacer. Ask your clinician or pharmacist to confirm device compatibility and follow your asthma action plan during sudden symptoms.