Research & Literature

LIMITATIONS OF CURRENT APPROACHES FOR THE TREATMENT OF ACROMEGALY.

Shanik MH

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2016; (22(2)):210-9 doi:10.4158/EP15825.RA.

Acromegaly presenting with low insulin-like growth factor-1 levels and diabetes: a case report.

Wijayaratne DR, Arambewela MH, Dalugama C, et al.

Journal of medical case reports 2015; (9()):241 doi:10.1186/s13256-015-0736-z.

6'6" United States Marine Seeks Treatment for Gynecomastia Only to Learn It Is All in His Head.

Young DB

Military medicine 2015; (180(12)):e1290-2 doi:10.7205/MILMED-D-15-00248.

Current therapies and mortality in acromegaly.

Găloiu S, Poiană C

Journal of medicine and life 2015; (8(4)):411-5.

Pasireotide: a novel treatment for patients with acromegaly.

Cuevas-Ramos D, Fleseriu M

Drug design, development and therapy 2016; (10()):227-39 doi:10.2147/DDDT.S77999.

Combined treatment with octreotide LAR and pegvisomant in patients with pituitary gigantism: clinical evaluation and genetic screening.

Mangupli R, Rostomyan L, Castermans E, et al.

Pituitary 2016; (19(5)):507-14 doi:10.1007/s11102-016-0732-3.

Alcohol septal ablation in obstructive acromegalic hypertrophic cardiomyopathy - a first case report.

Viveiros Monteiro A, Fiarresga A, Cacela D, et al.

Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 2016; (35(9)):499.e1-4.

Genetics of gigantism and acromegaly.

Hannah-Shmouni F, Trivellin G, Stratakis CA

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2016; (30-31()):37-41 doi:10.1016/j.ghir.2016.08.002.

Acromegaly: clinical features at diagnosis.

Vilar L, Vilar CF, Lyra R, et al.

Pituitary 2017; (20(1)):22-32 doi:10.1007/s11102-016-0772-8.

Diabetes in Patients With Acromegaly.

Hannon AM, Thompson CJ, Sherlock M

Current diabetes reports 2017; (17(2)):8 doi:10.1007/s11892-017-0838-7.

Efficacy of transsphenoidal surgery in achieving biochemical cure of growth hormone-secreting pituitary adenomas among patients with cavernous sinus invasion: a systematic review and meta-analysis.

Briceno V, Zaidi HA, Doucette JA, et al.

Neurological research 2017; (39(5)):387-398 doi:10.1080/01616412.2017.1296653.

Long-Term Endocrine Outcomes Following Endoscopic Endonasal Transsphenoidal Surgery for Acromegaly and Associated Prognostic Factors.

Babu H, Ortega A, Nuno M, et al.

Neurosurgery 2017; (81(2)):357-366 doi:10.1093/neuros/nyx020.

Outcome of Endoscopic Transsphenoidal Surgery for Acromegaly.

Kim JH, Hur KY, Lee JH, et al.

World neurosurgery 2017; (104()):272-278 doi:10.1016/j.wneu.2017.04.141.

Cardiovascular Disease in Acromegaly.

Sharma MD, Nguyen AV, Brown S, Robbins RJ

Methodist DeBakey cardiovascular journal 2017; (13(2)):64-67 doi:10.14797/mdcj-13-2-64.

[The mouth of patients with acromegaly].

Cortet-Rudelli C

Presse medicale (Paris, France : 1983) 2017; (46(9)):831-837 doi:10.1016/j.lpm.2017.09.001.

Transsphenoidal Surgery for Pituitary Tumors and Other Sellar Masses.

Owen TJ, Martin LG, Chen AV

The Veterinary clinics of North America. Small animal practice 2018; (48(1)):129-151 doi:10.1016/j.cvsm.2017.08.006.

Stereotactic Radiosurgery for Acromegaly: An International Multicenter Retrospective Cohort Study.

Ding D, Mehta GU, Patibandla MR, et al.

Neurosurgery 2019; (84(3)):717-725 doi:10.1093/neuros/nyy178.

Acromegalic Cardiomyopathy: An Overview of Risk Factors, Clinical Manifestations, and Therapeutic Options.

Goldberg MD, Vadera N, Yandrapalli S, Frishman WH

Cardiology in review 2018; (26(6)):307-311 doi:10.1097/CRD.0000000000000215.

Efficacy and safety of long-acting pasireotide in patients with somatostatin-resistant acromegaly: a multicenter study.

Shimon I, Adnan Z, Gorshtein A, et al.

Endocrine 2018; (62(2)):448-455 doi:10.1007/s12020-018-1690-5.

Adenoma size and postoperative IGF-1 levels predict surgical outcomes in acromegaly patients: results of the Swiss Pituitary Registry (SwissPit).

Kempf J, Schmitz A, Meier A, et al.

Swiss medical weekly 2018; (148()):w14653.

Pegvisomant therapy for acromegaly.

Freda PU

Expert review of endocrinology & metabolism 2006; (1(4)):489-498 doi:10.1586/17446651.1.4.489.

Biochemical following-up of treated acromegaly. Limitations of the current determinations of IGF-I and perspective.

Granada ML

Minerva endocrinologica 2019; (44(2)):143-158 doi:10.23736/S0391-1977.18.02922-X.

Association of Acromegaly and Central Sleep Apnea Syndrome.

Pazarlı AC, Köseoğlu Hİ, Kutlutürk F, Gökçe E

Turkish thoracic journal 2019; (20(2)):157-159 doi:10.5152/TurkThoracJ.2017.17003.

Is GH nadir during OGTT a reliable test for diagnosis of acromegaly in patients with abnormal glucose metabolism?

Dobri G, Niwattisaiwong S, Bena JF, et al.

Endocrine 2019; (64(1)):139-146 doi:10.1007/s12020-018-1805-z.

Surgical Results and Predictors of Initial and Delayed Remission for Growth Hormone-Secreting Pituitary Adenomas Using the 2010 Consensus Criteria in 162 Patients from a Single Center.

Shen M, Tang Y, Shou X, et al.

World neurosurgery 2019; (124()):e39-e50 doi:10.1016/j.wneu.2018.11.179.

PREDICTIVE MARKERS FOR POSTSURGICAL MEDICAL MANAGEMENT OF ACROMEGALY: A SYSTEMATIC REVIEW AND CONSENSUS TREATMENT GUIDELINE.

Ezzat S, Caspar-Bell GM, Chik CL, et al.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2019; (25(4)):379-393 doi:10.4158/EP-2018-0500.

Role of radiotherapy in the management of acromegaly.

Biermasz NR, Pereira AM, Neelis KJ, et al.

Expert review of endocrinology & metabolism 2006; (1(3)):449-460 doi:10.1586/17446651.1.3.449.

Predicting early post-operative remission in pituitary adenomas: evaluation of the modified knosp classification.

Buchy M, Lapras V, Rabilloud M, et al.

Pituitary 2019; (22(5)):467-475 doi:10.1007/s11102-019-00976-6.

Exosomal hsa-miR-21-5p derived from growth hormone-secreting pituitary adenoma promotes abnormal bone formation in acromegaly.

Xiong Y, Tang Y, Fan F, et al.

Translational research : the journal of laboratory and clinical medicine 2020; (215()):1-16 doi:10.1016/j.trsl.2019.07.013.

Acromegaly and ultrasound: how, when and why?

Parolin M, Dassie F, Vettor R, Maffei P

Journal of endocrinological investigation 2020; (43(3)):279-287 doi:10.1007/s40618-019-01111-9.

Long-term safety and treatment outcomes of pegvisomant in Japanese patients with acromegaly: results from the post-marketing surveillance.

Yamaguchi H, Shimatsu A, Okayama A, Sato T

Endocrine journal 2020; (67(2)):201-210 doi:10.1507/endocrj.EJ19-0266.

Pituitary surgery's epidemiology using a national inpatient database in Japan.

Hattori Y, Tahara S, Aso S, et al.

Acta neurochirurgica 2020; (162(6)):1317-1323 doi:10.1007/s00701-020-04270-4.

Acromegaly: 'You must know it to think of it'.

Boguszewski CL

European journal of endocrinology 2020; (183(1)):C1-C4.

Comparing Stereotactic Radiosurgery and Fractionated Stereotactic Radiotherapy in Treating patients with Growth Hormone-Secreting Adenomas: A Systematic Review and Meta-analysis.

Zheng Q, Huang Y, Lin W, et al.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2020; doi:10.4158/EP-2020-0110.

Management of persistent acromegaly following primary therapy: The current landscape in the UK.

Kyriakakis N, Seejore K, Hanafy A, Murray RD

Endocrinology, diabetes & metabolism 2020; (3(3)):e00158 doi:10.1002/edm2.158.

Updates in rare and not-so-rare complications of acromegaly: focus on respiratory function and quality of life in acromegaly.

Langlois F, Suarez GM, Fleseriu M

F1000Research 2020; (9()) doi:10.12688/f1000research.22683.1.

Gamma Knife radiosurgery for acromegaly: Evaluating the role of the biological effective dose associated with endocrine remission in a series of 42 consecutive cases.

Balossier A, Tuleasca C, Cortet-Rudelli C, et al.

Clinical endocrinology 2021; (94(3)):424-433 doi:10.1111/cen.14346.

Machine learning in predicting early remission in patients after surgical treatment of acromegaly: a multicenter study.

Qiao N, Shen M, He W, et al.

Pituitary 2021; (24(1)):53-61 doi:10.1007/s11102-020-01086-4.

A legendary sumo wrestler with gigantism or acromegaly? The case of Ikezuki Geitazaemon (1827-1850).

Takada K, Sasano M, Hayakawa S

Medical hypotheses 2020; (144()):110174 doi:10.1016/j.mehy.2020.110174.

[Selective screening of patients with associated somatic diseases as a method of early detection of acromegaly].

Antsiferov MB, Pronin VS, Alekseeva TM, et al.

Problemy endokrinologii 2021; (67(1)):20-30 doi:10.14341/probl12699.

[Acromegaly and it's cardiovascular implications].

Cadena-Obando DA, Remba-Shapiro I, Abreu-Rosario CG, Mercado M

Revista medica del Instituto Mexicano del Seguro Social 2021; (59(1)):73-80 doi:10.24875/RMIMSS.M21000054.

Improved AcroQoL scores in acromegaly after sagittal split ramus osteotomy with Le Fort I osteotomy.

Taguchi T, Kimizuka S, Takano K

Endocrinology, diabetes & metabolism case reports 2021; (2021()).

Value of Early Post-Operative Growth Hormone Testing in Predicting Long-Term Remission and Residual Disease after Transsphenoidal Surgery for Acromegaly.

Wang YY, Waqar M, Abou-Zeid A, et al.

Neuroendocrinology 2022; (112(4)):345-357 doi:10.1159/000517476.

Post-treatment heterogeneity of cardiometabolic risk in patients with acromegaly: The impact of GH and IGF-1.

Heydari M, Hashemi-Madani N, Emami Z, et al.

Endocrine research 2022; (47(1)):1-7 doi:10.1080/07435800.2021.1931298.

Endoscopic endonasal transsphenoidal surgery in acromegaly with conchal sphenoid sinus.

Yamazaki D, Ogiwara T, Hirayama S, et al.

British journal of neurosurgery 2023; (37(6)):1832-1834 doi:10.1080/02688697.2021.1940851.

Evaluation of Acromegaly patients with sleep disturbance related symptoms.

Celik D, Duyar SS, Aksu F, et al.

Pakistan journal of medical sciences 2021; (37(4)):1161-1165 doi:10.12669/pjms.37.4.4229.

Experience of Endoscopic Endonasal Approach for 803 Pituitary Tumors With Cavernous Sinus Invasion.

Zhu H, Li C, Gui S, et al.

The Journal of craniofacial surgery 2022; (33(2)):e118-e122 doi:10.1097/SCS.0000000000008049.

Neutrophil-to-Lymphocyte, Platelet-to-Lymphocyte Ratios, and Systemic Immune-Inflammation Index as Potential Biomarkers of Chronic Inflammation in Patients with Newly Diagnosed Acromegaly: A Single-Centre Study.

Szydełko J, Szydełko-Gorzkowicz M, Matyjaszek-Matuszek B

Journal of clinical medicine 2021; (10(17)) doi:10.3390/jcm10173997.

Diabetes Mellitus of Pituitary Origin: A Case Report.

Singla M, Kaur Saini J

TouchREVIEWS in endocrinology 2021; (17(1)):68-70 doi:10.17925/EE.2021.17.1.68.

Diagnosis and Treatment of Acromegaly: An Update.

Ershadinia N, Tritos NA

Mayo Clinic proceedings 2022; (97(2)):333-346 doi:10.1016/j.mayocp.2021.11.007.

[Cardiovascular complications associated with acromegaly. A state-of-the-art].

Concepción-Zavaleta M, Muñoz-Moreno J, Quispe-Flores M, et al.

Archivos de cardiologia de Mexico 2022; (92(4)):513-521 doi:10.24875/ACM.21000339.

Clinical Characteristics and Associated Factors of Colonic Polyps in Acromegaly.

Peng G, Li X, Zhou Y, et al.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2022; (130(11)):714-722 doi:10.1055/a-1913-7900.

Presence of cerebral microbleeds is associated with cognitive decline in acromegaly.

Xie Z, Zhuang Y, Zhang Z, Liu J

Frontiers in oncology 2022; (12()):948971 doi:10.3389/fonc.2022.948971.

[Acromegaly in the differential diagnosis of hearing loss].

Dzeranova LK, Lepeshkina LI, Shutova AS, et al.

Problemy endokrinologii 2023; (69(2)):31-37 doi:10.14341/probl13249.

Long-term control of acromegaly after pituitary surgery in South-Eastern Norway.

Falch CM, Dupont AK, Olarescu NC, et al.

Acta neurochirurgica 2023; (165(10)):3003-3010 doi:10.1007/s00701-023-05772-7.

Comparative effectiveness of endoscopic and microscopic adenoma removal in acromegaly.

Vassilyeva N, Mena N, Kirov K, Diatlova E

Frontiers in endocrinology 2023; (14()):1128345 doi:10.3389/fendo.2023.1128345.

Treatment of acromegaly with oral octreotide.

Remba-Shapiro I, Nachtigall LB

Best practice & research. Clinical endocrinology & metabolism 2024; (38(4)):101888 doi:10.1016/j.beem.2024.101888.

Pegvisomant and pasireotide in PRL and GH co-secreting vs GH-secreting Pit-NETs.

Araujo-Castro M, Biagetti B, Menéndez Torre E, et al.

Endocrine-related cancer 2024; (31(7)).

Prospective, Longitudinal Study of Cancer Predictors and Rates in a New York City Cohort of 598 Patients With Acromegaly.

Freda PU, Bruce JN, Jin Z, et al.

The Journal of clinical endocrinology and metabolism 2025; (110(5)):1247-1257 doi:10.1210/clinem/dgae469.

Aortic root dilation in acromegaly.

Yeboah-Kordieh YA, Arif W, Weisman D, Salvatori R

BMJ case reports 2024; (17(7)) doi:10.1136/bcr-2024-260204.

Medical treatment of acromegaly - When the tumor size matters: A narrative review.

Doknic M, Stojanovic M, Miljic D, Milicevic M

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2024; (78()):101608 doi:10.1016/j.ghir.2024.101608.

Stereotactic Radiosurgery and Fractionated Stereotactic Radiotherapy With a Linear Accelerator (LINAC) for Acromegaly Remission: Clinical Experience From a Tertiary Neurological Center in Latin America.

Santos-Santos RI, Flores-Vázquez JG, Rodriguez-Hernandez LA, et al.

Cureus 2025; (17(7)):e88708 doi:10.7759/cureus.88708.

Rethinking MRI Protocols for Pituitary Microadenomas: Prioritizing Non-Contrast Imaging for Safe Follow-Up.

Zarei F, Nematollahi F, Jalil A, et al.

Tomography (Ann Arbor, Mich.) 2025; (11(9)) doi:10.3390/tomography11090105.

Gender differences in the glycometabolic and cardiovascular features of acromegaly.

Gatto F, Arecco A, De Alcubierre D, et al.

Pituitary 2026; (29(1)):34 doi:10.1007/s11102-025-01629-7.

Acromegaly presenting with normal insulin-like growth factor-1 levels in a patient with advanced liver cirrhosis.

Kilcoyne C, Burke K, O'Reilly MW, et al.

BMJ case reports 2026; (19(2)) doi:10.1136/bcr-2025-266505.