Research & Literature

Patients with biopsy-proven nephrosclerosis and moderately impaired renal function have a higher risk for cardiovascular disease: 15 years' experience in a single, kidney disease center.

Suzuki H, Kobayashi K, Ishida Y, et al.

Therapeutic advances in cardiovascular disease 2015; (9(3)):77-86 doi:10.1177/1753944715578596.

[Hypertensive emergencies and urgencies].

Phan DG, Dreyfuss-Tubiana C, Blacher J

Presse medicale (Paris, France : 1983) 2015; (44(7-8)):737-44.

Practical Approach to Detection and Management of Chronic Kidney Disease for the Primary Care Clinician.

Vassalotti JA, Centor R, Turner BJ, et al.

The American journal of medicine 2016; (129(2)):153-162.e7.

Hypertension-attributed nephropathy: what's in a name?

Freedman BI, Cohen AH

Nature reviews. Nephrology 2016; (12(1)):27-36 doi:10.1038/nrneph.2015.172.

Prognostic Value of Tubulointerstitial Lesions, Urinary N-Acetyl-β-d-Glucosaminidase, and Urinary β2-Microglobulin in Patients with Type 2 Diabetes and Biopsy-Proven Diabetic Nephropathy.

Mise K, Hoshino J, Ueno T, et al.

Clinical journal of the American Society of Nephrology : CJASN 2016; (11(4)):593-601 doi:10.2215/CJN.04980515.

Effect of Proteinuria and Glomerular Filtration Rate on Renal Outcome in Patients with Biopsy-Proven Benign Nephrosclerosis.

Sumida K, Hoshino J, Ueno T, et al.

PloS one 2016; (11(1)):e0147690 doi:10.1371/journal.pone.0147690.

Clinico-pathological characteristics and outcomes of patients with biopsy-proven hypertensive nephrosclerosis: a retrospective cohort study.

Liang S, Le W, Liang D, et al.

BMC nephrology 2016; (17()):42 doi:10.1186/s12882-016-0254-2.

Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis.

Currie G, Taylor AH, Fujita T, et al.

BMC nephrology 2016; (17(1)):127 doi:10.1186/s12882-016-0337-0.

APOL1 Risk Alleles are Associated with More Severe Arteriosclerosis in Renal Resistance Vessels with Aging and Hypertension.

Hughson MD, Hoy WE, Mott SA, et al.

Kidney international reports 2016; (1(1)):10-23 doi:10.1016/j.ekir.2016.03.002.

Kidney disease in the elderly: biopsy based data from 14 renal centers in Poland.

Perkowska-Ptasinska A, Deborska-Materkowska D, Bartczak A, et al.

BMC nephrology 2016; (17(1)):194 doi:10.1186/s12882-016-0410-8.

Albuminuria changes are associated with subsequent risk of end-stage renal disease and mortality.

Carrero JJ, Grams ME, Sang Y, et al.

Kidney international 2017; (91(1)):244-251 doi:10.1016/j.kint.2016.09.037.

Adherence to guidelines for creatinine and potassium monitoring and discontinuation following renin-angiotensin system blockade: a UK general practice-based cohort study.

Schmidt M, Mansfield KE, Bhaskaran K, et al.

BMJ open 2017; (7(1)):e012818 doi:10.1136/bmjopen-2016-012818.

Focal Segmental Glomerulosclerosis.

Rosenberg AZ, Kopp JB

Clinical journal of the American Society of Nephrology : CJASN 2017; (12(3)):502-517 doi:10.2215/CJN.05960616.

Validation of the Kidney Failure Risk Equation in Manitoba.

Whitlock RH, Chartier M, Komenda P, et al.

Canadian journal of kidney health and disease 2017; (4()):2054358117705372 doi:10.1177/2054358117705372.

Hyperkalemia After Initiating Renin-Angiotensin System Blockade: The Stockholm Creatinine Measurements (SCREAM) Project.

Bandak G, Sang Y, Gasparini A, et al.

Journal of the American Heart Association 2017; (6(7)) doi:10.1161/JAHA.116.005428.

Clinico-pathological features of kidney disease in diabetic cases.

Furuichi K, Shimizu M, Okada H, et al.

Clinical and experimental nephrology 2018; (22(5)):1046-1051 doi:10.1007/s10157-018-1556-4.

Interstitial inflammation and interstitial fibrosis and tubular atrophy predict renal survival in lupus nephritis.

Wilson PC, Kashgarian M, Moeckel G

Clinical kidney journal 2018; (11(2)):207-218 doi:10.1093/ckj/sfx093.

Clinicopathological predictors for progression of chronic kidney disease in nephrosclerosis: a biopsy-based cohort study.

Yamanouchi M, Hoshino J, Ubara Y, et al.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2019; (34(7)):1182-1188 doi:10.1093/ndt/gfy121.

Use of Renin-Angiotensin System Blockade in Advanced CKD: An NKF-KDOQI Controversies Report.

Weir MR, Lakkis JI, Jaar B, et al.

American journal of kidney diseases : the official journal of the National Kidney Foundation 2018; (72(6)):873-884 doi:10.1053/j.ajkd.2018.06.010.

One Actor, Many Roles: Histopathologies Associated With APOL1 Genetic Variants.

Kopp JB, Rosenberg AZ

Advances in anatomic pathology 2019; (26(3)):215-219 doi:10.1097/PAP.0000000000000221.

Risk factors for hypertensive crisis in adult patients: a systematic review protocol.

Benenson I, Waldron FA, Jadotte YT, Holly C

JBI database of systematic reviews and implementation reports 2019; (17(11)):2343-2349 doi:10.11124/JBISRIR-2017-003996.

Hypertensive Emergencies: A Review of Common Presentations and Treatment Options.

Brathwaite L, Reif M

Cardiology clinics 2019; (37(3)):275-286 doi:10.1016/j.ccl.2019.04.003.

The Key Role of Epithelial to Mesenchymal Transition (EMT) in Hypertensive Kidney Disease.

Seccia TM, Caroccia B, Piazza M, Rossi GP

International journal of molecular sciences 2019; (20(14)) doi:10.3390/ijms20143567.

Novel Haplotype Indicator for End-Stage Renal Disease Progression among Saudi Patients.

Cyrus C, Chathoth S, Vatte C, et al.

International journal of nephrology 2019; (2019()):1095215 doi:10.1155/2019/1095215.

Chronic Kidney Disease Diagnosis and Management: A Review.

Chen TK, Knicely DH, Grams ME

JAMA 2019; (322(13)):1294-1304 doi:10.1001/jama.2019.14745.

Hypertensive kidney disease: a true epidemic or rare disease?

Stompór T, Perkowska-Ptasińska A

Polish archives of internal medicine 2020; (130(2)):130-139 doi:10.20452/pamw.15150.

Clinical Phenotypes and Long-term Prognosis in White Patients With Biopsy-Verified Hypertensive Nephrosclerosis.

Øvrehus MA, Oldereid TS, Dadfar A, et al.

Kidney international reports 2020; (5(3)):339-347 doi:10.1016/j.ekir.2019.12.010.

Chronic kidney disease in adults: assessment and management.

Forbes A, Gallagher H

Clinical medicine (London, England) 2020; (20(2)):128-132 doi:10.7861/clinmed.cg.20.2.

Clinical value of multiorgan damage in hypertensive crises: A prospective follow-up study.

Ma H, Jiang M, Fu Z, et al.

Journal of clinical hypertension (Greenwich, Conn.) 2020; (22(5)):914-923 doi:10.1111/jch.13848.

Hypertensive emergencies and urgencies in emergency departments: a systematic review and meta-analysis.

Astarita A, Covella M, Vallelonga F, et al.

Journal of hypertension 2020; (38(7)):1203-1210 doi:10.1097/HJH.0000000000002372.

Hypertensive nephrosclerosis: wider kidney biopsy indications may be needed to improve diagnostics.

Hallan SI, Øvrehus MA, Bjørneklett R, et al.

Journal of internal medicine 2021; (289(1)):69-83 doi:10.1111/joim.13146.

Resistant Hypertension in Chronic Kidney Disease (CKD): Prevalence, Treatment Particularities, and Research Agenda.

Georgianos PI, Agarwal R

Current hypertension reports 2020; (22(10)):84 doi:10.1007/s11906-020-01081-x.

Performance of the Kidney Failure Risk Equation by Disease Etiology in Advanced CKD.

Hundemer GL, Tangri N, Sood MM, et al.

Clinical journal of the American Society of Nephrology : CJASN 2020; (15(10)):1424-1432 doi:10.2215/CJN.03940320.

Salt-sensitive hypertension in chronic kidney disease: distal tubular mechanisms.

Bovée DM, Cuevas CA, Zietse R, et al.

American journal of physiology. Renal physiology 2020; (319(5)):F729-F745 doi:10.1152/ajprenal.00407.2020.

Incorporating kidney disease measures into cardiovascular risk prediction: Development and validation in 9 million adults from 72 datasets.

Matsushita K, Jassal SK, Sang Y, et al.

EClinicalMedicine 2020; (27()):100552 doi:10.1016/j.eclinm.2020.100552.

Executive summary of the KDIGO 2021 Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease.

Cheung AK, Chang TI, Cushman WC, et al.

Kidney international 2021; (99(3)):559-569 doi:10.1016/j.kint.2020.10.026.

Commentary on the KDIGO 2021 Clinical Practice Guideline for the Management of Blood Pressure in CKD.

Mann JFE, Chang TI, Cushman WC, et al.

Current cardiology reports 2021; (23(9)):132 doi:10.1007/s11886-021-01559-3.

Home Blood Pressure Monitoring: Current Status and New Developments.

Kario K

American journal of hypertension 2021; (34(8)):783-794 doi:10.1093/ajh/hpab017.

CE: Hypertensive Emergencies: A Review.

Mathews EP, Newton F, Sharma K

The American journal of nursing 2021; (121(10)):24-35 doi:10.1097/01.NAJ.0000794104.21262.86.

Clinicopathological discordance in biopsy-proven nephrosclerosis: a nationwide cross-sectional study of the Japan Renal Biopsy Registry (J-RBR).

Sumida K, Takeda A, Furuichi K, et al.

Clinical and experimental nephrology 2022; (26(4)):325-332 doi:10.1007/s10157-021-02161-1.

Molecular Mechanisms of Hypertensive Nephropathy: Renoprotective Effect of Losartan through Hsp70.

Costantino VV, Gil Lorenzo AF, Bocanegra V, Vallés PG

Cells 2021; (10(11)) doi:10.3390/cells10113146.

Autopsy study examining non-chronic kidney disease versus chronic kidney disease caused by hypertensive-nephrosclerosis in elderly subjects.

Yamaguchi Y, Takei T, Matsuda Y, et al.

Clinical and experimental nephrology 2022; (26(6)):530-539 doi:10.1007/s10157-022-02189-x.

Controversies in Hypertension II: The Optimal Target Blood Pressure.

Filippone EJ, Foy AJ, Naccarelli GV

The American journal of medicine 2022; (135(10)):1168-1177.e3 doi:10.1016/j.amjmed.2022.05.009.

The Management of Hypertensive Emergencies-Is There a "Magical" Prescription for All?

Balahura AM, Moroi ȘI, Scafa-Udrişte A, et al.

Journal of clinical medicine 2022; (11(11)) doi:10.3390/jcm11113138.

Interest of a Kidney Biopsy to Rule out ANCA-Associated Renal Vasculitis in Glomerulonephritis Patients with a Positive ANCA.

Garo F, Aglae C, Perrochia H, et al.

Case reports in nephrology and dialysis 2022; (12(1)):73-80 doi:10.1159/000521862.

Including measures of chronic kidney disease to improve cardiovascular risk prediction by SCORE2 and SCORE2-OP.

Matsushita K, Kaptoge S, Hageman SHJ, et al.

European journal of preventive cardiology 2023; (30(1)):8-16 doi:10.1093/eurjpc/zwac176.

Histological Spectrum of Clinical Kidney Disease in Type 2 Diabetes Mellitus Patients with special Reference to nonalbuminuric Diabetic Nephropathy: A Kidney Biopsy-based Study.

Prakash J, Patel PS, Iqbal M, et al.

The Journal of the Association of Physicians of India 2022; (70(8)):11-12 doi:10.5005/japi-11001-0060.

Low Adherence to Kidney Disease: Improving Global Outcomes 2012 CKD Clinical Practice Guidelines Despite Clear Evidence of Utility.

James G, Garcia Sanchez JJ, Carrero JJ, et al.

Kidney international reports 2022; (7(9)):2059-2070 doi:10.1016/j.ekir.2022.05.033.

Submaximal Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Dosing Among Persons With Proteinuria.

Chu CD, Powe NR, Estrella MM, et al.

Mayo Clinic proceedings 2022; (97(11)):2099-2106 doi:10.1016/j.mayocp.2022.07.010.

Hypertension in chronic kidney disease: What lies behind the scene.

Ameer OZ

Frontiers in pharmacology 2022; (13()):949260 doi:10.3389/fphar.2022.949260.

Progression of Chronic Kidney Disease Risk Categories and Risk of Cardiovascular Disease and Total Mortality: Coronary Artery Risk Development in Young Adults Cohort.

Choi Y, Jacobs DR, Shroff GR, et al.

Journal of the American Heart Association 2022; (11(21)):e026685 doi:10.1161/JAHA.122.026685.

Impact of diabetes on the effects of sodium glucose co-transporter-2 inhibitors on kidney outcomes: collaborative meta-analysis of large placebo-controlled trials.

,

Lancet (London, England) 2022; (400(10365)):1788-1801 doi:10.1016/S0140-6736(22)02074-8.

Renal Fibrosis in Lupus Nephritis.

Sciascia S, Cozzi M, Barinotti A, et al.

International journal of molecular sciences 2022; (23(22)) doi:10.3390/ijms232214317.

Case report: Area of focus in a case of malignant hypertension.

Bosisio FG, Mingardi D, Moretti E, et al.

Frontiers in cardiovascular medicine 2022; (9()):1108666 doi:10.3389/fcvm.2022.1108666.

The Kidney Failure Risk Equation: Evaluation of Novel Input Variables including eGFR Estimated Using the CKD-EPI 2021 Equation in 59 Cohorts.

Grams ME, Brunskill NJ, Ballew SH, et al.

Journal of the American Society of Nephrology : JASN 2023; (34(3)):482-494 doi:10.1681/ASN.0000000000000050.

Should we CLICK on chlorthalidone for treatment-resistant hypertension in chronic kidney disease?

Agarwal R

Clinical kidney journal 2023; (16(5)):793-796 doi:10.1093/ckj/sfac272.

The association between dual RAAS inhibition and risk of acute kidney injury and hyperkalemia in patients with diabetic kidney disease: a systematic review and meta-analysis.

Whitlock R, Leon SJ, Manacsa H, et al.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2023; (38(11)):2503-2516 doi:10.1093/ndt/gfad101.

[Classical nephroprotection: Renin angiotensin aldosterone system inhibitors].

Egocheaga MI, Drak Y, Otero V

Semergen 2023; (49 Suppl 1()):102018 doi:10.1016/j.semerg.2023.102018.

Hypertension in chronic kidney disease-treatment standard 2023.

Georgianos PI, Agarwal R

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2023; (38(12)):2694-2703 doi:10.1093/ndt/gfad118.

Clinical Outcomes in Hypertensive Emergency: A Systematic Review and Meta-Analysis.

Siddiqi TJ, Usman MS, Rashid AM, et al.

Journal of the American Heart Association 2023; (12(14)):e029355 doi:10.1161/JAHA.122.029355.

Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes: An Individual-Participant Data Meta-Analysis.

, Grams ME, Coresh J, et al.

JAMA 2023; (330(13)):1266-1277 doi:10.1001/jama.2023.17002.

Clinical Profile of Patients with Hypertensive Emergency Referred to a Tertiary Hospital in the Western Cape Province of South Africa.

Talle MA, Doubell AF, Robbertse PS, et al.

Current hypertension reviews 2023; (19(3)):194-205 doi:10.2174/0115734021266958231101094556.

[Retard chronic kidney disease progression].

Schuller M, Saritas T

Deutsche medizinische Wochenschrift (1946) 2024; (149(6)):320-325 doi:10.1055/a-1941-7057.

Association of Albuminuria With Chronic Kidney Disease Progression in Persons With Chronic Kidney Disease and Normoalbuminuria : A Cohort Study.

Verma A, Schmidt IM, Claudel S, et al.

Annals of internal medicine 2024; (177(4)):467-475 doi:10.7326/M23-2814.

Evaluation and management of hypertensive emergency.

Miller JB, Hrabec D, Krishnamoorthy V, et al.

BMJ (Clinical research ed.) 2024; (386()):e077205 doi:10.1136/bmj-2023-077205.

Rates of Acute Brain Injury Among Severely Hypertensive Patients Seen in the Emergency Department.

Ishak A, Kamel H, Kaiser JH, et al.

The Neurohospitalist 2024; (14(4)):389-395 doi:10.1177/19418744241257032.

Kidney Biopsy Findings Among Patients With Diabetes in the Cleveland Clinic Kidney Biopsy Epidemiology Project.

Kwon AG, Sawaf H, Portalatin G, et al.

Kidney medicine 2024; (6(10)):100889 doi:10.1016/j.xkme.2024.100889.

Managing malignant hypertension with renal TMA: a case for caution in blood-pressure reduction.

Iwamura N, Matsukuma Y, Katafuchi E, et al.

CEN case reports 2025; (14(2)):271-279 doi:10.1007/s13730-024-00933-8.

Clinical characteristics and outcomes of patients on haemodialysis at Jimma medical center, Ethiopia: a 7-Year review.

Tafese ST, Abera EG, Mersha MD, Woldemariam MB

BMC nephrology 2024; (25(1)):420 doi:10.1186/s12882-024-03860-z.

Diuretics in patients with chronic kidney disease.

Agarwal R, Verma A, Georgianos PI

Nature reviews. Nephrology 2025; (21(4)):264-278 doi:10.1038/s41581-024-00918-x.

Early administration of caplacizumab combined with plasma exchange for thrombotic microangiopathy due to malignant hypertension: a case report.

Okawa H, Wada Y, Takeuchi K, et al.

CEN case reports 2025; (14(3)):442-449 doi:10.1007/s13730-025-00978-3.

Novel Potassium Binders in Reduction of Hyperkalemia and Optimization of RAAS Inhibitors Treatment in Patients with Chronic Kidney Disease or Heart Failure: A Systematic Review and Meta-analysis.

Huang N, Xu Y, Liu C, et al.

Drugs 2025; (85(8)):1013-1031 doi:10.1007/s40265-025-02198-6.

Hypertensive Nephrosclerosis: Pathological Changes and Overlap with Diabetic Nephropathy.

Qasim H, Ktaifan M, Awawdeh A, et al.

Cureus 2025; (17(9)):e92949 doi:10.7759/cureus.92949.

Cardiovascular and renal outcomes according to KDIGO stages of chronic kidney disease in the Spanish population: Insights from real-world evidence.

Santamaria R, Escobar C, Aranda U, et al.

Nefrologia 2025; (45(8)):501340 doi:10.1016/j.nefroe.2025.501340.

Hypertension and age-related focal global glomerulosclerosis are associated with biomarkers for cellular senescence.

Hughson MD, Ali AA, Okabayashi Y, et al.

Physiological reports 2026; (14(3)):e70730 doi:10.14814/phy2.70730.

Nephrosclerosis-Related Histopathological Findings by Cortical Region From a Japanese Community-Based Study.

Marumoto H, Sasaki T, Oishi E, et al.

Kidney medicine 2026; (8(2)):101194 doi:10.1016/j.xkme.2025.101194.

Hypertensive Havoc: When Malignant Hypertension Mimics Thrombotic Thrombocytopenic Purpura.

Kim S, Pathak A, Koch M

Cureus 2026; (18(1)):e101117 doi:10.7759/cureus.101117.

Causal Effects of Renin-Angiotensin-Aldosterone System Inhibition on Renal Function in Patients With Chronic Kidney Disease: A Quasi-Experimental Study.

Oh TR, Park J, Choi HS, et al.

Clinical and translational science 2026; (19(4)):e70533 doi:10.1111/cts.70533.

Mineralocorticoid Receptor Antagonists in Chronic Kidney Disease: Clinical Evidence, Pharmacology, and Drug-Drug Interactions for Personalized Management of Hyperkalemia.

Hirai T, Katayama K

International journal of molecular sciences 2026; (27(10)) doi:10.3390/ijms27104272.

An Uncommon Presentation of Hypertensive Emergency in a Young Patient: A Case Report.

Tran J, Malka MS, Curato M

Cureus 2026; (18(7)):e113317 doi:10.7759/cureus.113317.