Skip to content
PubMed This is a summary of 12 peer-reviewed journal articles Updated
Gynecology

Diagnosis & Staging: Why Hysteroscopy is the Gold Standard

At a Glance

Hysteroscopy is the gold standard for diagnosing Asherman syndrome because it lets doctors directly see and treat uterine scar tissue. While tests like saline sonograms help with initial screening, a hysteroscopy is required to grade adhesion severity and evaluate the remaining uterine lining.

Confirming a diagnosis of Asherman syndrome requires moving beyond standard imaging to a direct view of the uterine cavity. While tools like a standard ultrasound provide a “silhouette” of the uterus, they often lack the detail needed to plan effective treatment [1][2].

The Gold Standard: Hysteroscopy

Hysteroscopy is considered the “gold standard” for both diagnosing and staging Asherman syndrome [3][4]. During this procedure, a doctor inserts a hysteroscope—a thin, lighted camera—through the cervix to see the inside of the uterus directly [3].

  • Direct Visualization: Unlike other tests, a hysteroscopy allows the doctor to see the exact location, texture, and color of the scar tissue [4].
  • Assessment of Quality: The doctor can evaluate the health of the remaining endometrium (lining) and see if the openings to the fallopian tubes (tubal ostia) are clear [1][5].
  • See and Treat: Often, a diagnostic hysteroscopy can transition immediately into an operative one, where the doctor begins to carefully remove the adhesions [2].

Diagnostic Bridge Tests

Before recommending surgery, your doctor will likely use intermediate imaging tests to investigate your symptoms:

  • Saline Infusion Sonohysterography (SIS/SHG): Often called a saline sonogram, this is a first-line diagnostic test. A small amount of sterile saline is introduced into the uterus during an ultrasound to distend the walls. This creates a clear picture of any adhesions blocking the cavity and serves as a highly sensitive bridge to a hysteroscopy [4][1].
  • HSG (X-ray with dye): This test shows the “outline” of the uterus. If the dye doesn’t fill a certain area, it suggests a blockage, but it cannot tell the difference between a thick scar, a small polyp, or a simple air bubble (a “false positive”) [1][2].
  • 3D Ultrasound: This is a powerful screening tool that can help estimate how much of the cavity is open [6]. However, it often underestimates the complexity or “toughness” of the adhesions compared to what the doctor finds during surgery [7][2].

Staging and Severity

To help predict how well treatment will work, doctors “stage” the disease. There is no single universal system, but most doctors use the American Fertility Society (AFS) or March classification systems [8][7]. These systems assign points based on:

  1. Extent of Disease: What percentage of the uterus is “glued” together? (e.g., less than 1/3, 1/3 to 2/3, or more than 2/3) [9][10].
  2. Type of Adhesions: Are they filmy (thin and easy to break) or dense/fibrous (thick, tough, and opaque)? [9][5].
  3. Menstrual Pattern: Has your period stopped entirely, or is it just lighter? [11].

What to Look for in Your Report

If you have a diagnostic or surgical report, look for these specific details to understand the severity of your case:

  • Cavity Occlusion: Look for a percentage (e.g., “50% occlusion”) [9].
  • Tubal Ostia: The report should state if the openings to the fallopian tubes were “visualized” or “blocked” [9][5].
  • Endometrial Description: Descriptions like “pale” or “atrophic” lining can indicate that the foundation layer is damaged, whereas “pink” or “vascular” lining is a more positive sign [1][5].

While higher “grades” of scarring are generally more challenging to treat, research shows that the skill of the surgeon and the health of the remaining lining are often more important for your final outcome than the initial score [8][12].

Common questions in this guide

Why is hysteroscopy the gold standard for diagnosing Asherman syndrome?
Hysteroscopy allows doctors to insert a thin, lighted camera directly into the cervix and uterus. This provides a direct view of the scar tissue's location, texture, and severity, allowing them to assess the remaining healthy tissue and often remove adhesions during the same procedure.
What is a saline sonogram (SIS) and how is it used for Asherman syndrome?
A saline sonogram, or SIS, uses a small amount of sterile saltwater to gently expand the uterus during an ultrasound. It provides a clear picture of any adhesions blocking the cavity and acts as a highly sensitive screening step before a surgical hysteroscopy.
How do doctors grade or stage the severity of Asherman syndrome?
Doctors generally use the American Fertility Society (AFS) or March classification systems. These grade severity based on what percentage of the uterus is blocked by scar tissue, the thickness of the adhesions, and whether your menstrual cycle has stopped or become lighter.
What is the difference between filmy and dense adhesions on my report?
Filmy adhesions are thin scar tissue bands that are relatively easy to break. Dense or fibrous adhesions are thick, tough, and opaque, which makes them more challenging to remove during surgery.
What key details should I look for in my diagnostic hysteroscopy report?
Your report should mention the percentage of your uterine cavity that is blocked, whether the openings to your fallopian tubes (tubal ostia) are clear, and the visual health of your remaining endometrial lining.

Questions to Ask Your Doctor

Curated prompts to bring to your next appointment.

  1. 1.Which staging system (e.g., AFS or March) did you use to grade the severity of my adhesions?
  2. 2.Were you able to see both tubal ostia (the openings to the fallopian tubes) during the procedure?
  3. 3.What percentage of my uterine cavity was blocked by scar tissue?
  4. 4.Were my adhesions 'filmy' or 'dense and fibrous,' and how does that affect my treatment plan?
  5. 5.How does the appearance of my endometrial lining in the unaffected areas look?

Questions For You

Tap a prompt to share your answer — we'll use it plus this page's context to start a tailored conversation.

References

References (12)
  1. 1

    Comparative Analysis of Hysterosalpingography and Diagnostic Hysteroscopy Findings in Infertility Evaluation.

    G M, M S

    Cureus 2025; (17(4)):e81789 doi:10.7759/cureus.81789.

    PMID: 40330349
  2. 2

    Asherman's syndrome: current perspectives on diagnosis and management.

    Dreisler E, Kjer JJ

    International journal of women's health 2019; (11()):191-198 doi:10.2147/IJWH.S165474.

    PMID: 30936754
  3. 3

    Mini-Review of the New Therapeutic Possibilities in Asherman Syndrome-Where Are We after One Hundred and Twenty-Six Years?

    Doroftei B, Dabuleanu AM, Ilie OD, et al.

    Diagnostics (Basel, Switzerland) 2020; (10(9)) doi:10.3390/diagnostics10090706.

    PMID: 32957624
  4. 4

    Value of 2D ultrasonography in the diagnosis and evaluation of intrauterine adhesions - a prospective study.

    Huang R, Huang X, Li S, et al.

    Reproductive biomedicine online 2024; (49(2)):103771 doi:10.1016/j.rbmo.2023.103771.

    PMID: 38761561
  5. 5

    Review of Asherman syndrome and its hysteroscopic treatment outcomes: experience in a low-resource setting.

    Siferih M, Gebre T, Hunduma F, et al.

    BMC women's health 2024; (24(1)):99 doi:10.1186/s12905-024-02944-0.

    PMID: 38326846
  6. 6

    Diagnostic accuracy of three-dimensional transvaginal ultrasound for intrauterine adhesions: a systematic review and meta-analysis.

    Huang L, Huang Z, Hu B

    Frontiers in medicine 2025; (12()):1690719 doi:10.3389/fmed.2025.1690719.

    PMID: 41341821
  7. 7

    Fertility and anatomical outcomes following hysteroscopic adhesiolysis: An 11-year retrospective cohort study to validate a new classification system for intrauterine adhesions (Urman-Vitale Classification System).

    Urman B, Yakin K, Ertas S, et al.

    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2024; (165(2)):644-654 doi:10.1002/ijgo.15262.

    PMID: 38013507
  8. 8

    Patient-reported menstrual and obstetric outcomes following hysteroscopic adhesiolysis for Asherman syndrome.

    Morales B, Movilla P, Wang J, et al.

    F&S reports 2021; (2(1)):118-125 doi:10.1016/j.xfre.2021.01.002.

    PMID: 34223282
  9. 9

    Intrauterine adhesions: What is the pregnancy rate after hysteroscopic management?

    Capmas P, Mihalache A, Duminil L, et al.

    Journal of gynecology obstetrics and human reproduction 2020; (49(7)):101797 doi:10.1016/j.jogoh.2020.101797.

    PMID: 32413519
  10. 10

    Estrogen therapy before hysteroscopic adhesiolysis improves the fertility outcome in patients with intrauterine adhesions.

    Zhang L, Wang M, Zhang Q, et al.

    Archives of gynecology and obstetrics 2019; (300(4)):933-939 doi:10.1007/s00404-019-05249-y.

    PMID: 31350664
  11. 11

    Effect of hysteroscopic adhesiolysis on recurrence, menstruation and pregnancy outcomes in patients with different degrees of intrauterine adhesions.

    Wang L, Guo C, Cao H

    American journal of translational research 2022; (14(1)):484-490.

    PMID: 35173868
  12. 12

    Logistic regression analyses of factors affecting fertility of intrauterine adhesions patients.

    Zhao X, Liu Y, Zhang A, et al.

    Annals of translational medicine 2020; (8(4)):49 doi:10.21037/atm.2019.11.115.

    PMID: 32175343

This page provides educational information about Asherman syndrome diagnosis and staging. It is not a substitute for professional medical advice from your gynecologist or reproductive endocrinologist.

Get notified when new evidence is published on Asherman syndrome.

We monitor PubMed for new peer-reviewed studies on this topic and email a short summary when something meaningful changes.