Research & Literature

MicroRNA-29b Inhibits Endometrial Fibrosis by Regulating the Sp1-TGF-β1/Smad-CTGF Axis in a Rat Model.

Li J, Du S, Sheng X, et al.

Reproductive sciences (Thousand Oaks, Calif.) 2016; (23(3)):386-94 doi:10.1177/1933719115602768.

Results of centralized Asherman surgery, 2003-2013.

Hanstede MM, van der Meij E, Goedemans L, Emanuel MH

Fertility and sterility 2015; (104(6)):1561-8.e1.

Role of epithelial-mesenchymal transition in proliferative vitreoretinopathy.

Tamiya S, Kaplan HJ

Experimental eye research 2016; (142()):26-31.

Reproductive Outcome of Patients with Asherman's Syndrome: A SAIMS Experience.

Bhandari S, Bhave P, Ganguly I, et al.

Journal of reproduction & infertility 2015; (16(4)):229-35.

Hysteroscopic adhesiolysis: efficacy and safety.

Sanad AS, Aboulfotouh ME

Archives of gynecology and obstetrics 2016; (294(2)):411-6 doi:10.1007/s00404-016-4107-9.

Intrauterine Adhesions Following Miscarriage: Look and Learn.

Gilman AR, Dewar KM, Rhone SA, Fluker MR

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC 2016; (38(5)):453-7.

A prospective, randomized, controlled trial comparing two doses of oestrogen therapy after hysteroscopic adhesiolysis to prevent intrauterine adhesion recurrence.

Guo J, Li TC, Liu Y, et al.

Reproductive biomedicine online 2017; (35(5)):555-561 doi:10.1016/j.rbmo.2017.07.011.

N-cadherin identifies human endometrial epithelial progenitor cells by in vitro stem cell assays.

Nguyen HPT, Xiao L, Deane JA, et al.

Human reproduction (Oxford, England) 2017; (32(11)):2254-2268 doi:10.1093/humrep/dex289.

The birth weight in pregnant women with Asherman syndrome compared to normal intrauterine cavity: A case-control study.

Baradwan S, Baradwan A, Bashir M, Al-Jaroudi D

Medicine 2018; (97(32)):e11797 doi:10.1097/MD.0000000000011797.

Uterine stem cells: from basic research to advanced cell therapies.

Santamaria X, Mas A, Cervelló I, et al.

Human reproduction update 2018; (24(6)):673-693 doi:10.1093/humupd/dmy028.

Asherman's syndrome: current perspectives on diagnosis and management.

Dreisler E, Kjer JJ

International journal of women's health 2019; (11()):191-198 doi:10.2147/IJWH.S165474.

Estrogen therapy before hysteroscopic adhesiolysis improves the fertility outcome in patients with intrauterine adhesions.

Zhang L, Wang M, Zhang Q, et al.

Archives of gynecology and obstetrics 2019; (300(4)):933-939 doi:10.1007/s00404-019-05249-y.

Early Second-Look Hysteroscopy: Prevention and Treatment of Intrauterine Post-surgical Adhesions.

Sebbag L, Even M, Fay S, et al.

Frontiers in surgery 2019; (6()):50 doi:10.3389/fsurg.2019.00050.

CSF1-associated decrease in endometrial macrophages may contribute to Asherman's syndrome.

Liu D, Wang J, Zhao G, et al.

American journal of reproductive immunology (New York, N.Y. : 1989) 2020; (83(1)):e13191 doi:10.1111/aji.13191.

Efficacy of silicone sheet as a personalized barrier for preventing adhesion reformation after hysteroscopic adhesiolysis of intrauterine adhesions.

Azumaguchi A, Henmi H, Saito T

Reproductive medicine and biology 2019; (18(4)):378-383 doi:10.1002/rmb2.12294.

Meta-analysis of the use of hyaluronic acid gel to prevent intrauterine adhesions after miscarriage.

Fei Z, Xin X, Fei H, Yuechong C

European journal of obstetrics, gynecology, and reproductive biology 2020; (244()):1-4 doi:10.1016/j.ejogrb.2019.10.018.

Endothelium-mediated contributions to fibrosis.

Sun X, Nkennor B, Mastikhina O, et al.

Seminars in cell & developmental biology 2020; (101()):78-86 doi:10.1016/j.semcdb.2019.10.015.

Secondary Prevention of Intrauterine Adhesions Following Hysteroscopic Surgery in Women With Asherman Syndrome: Is Something Better Than Nothing?

Kelley AS, Giuliani E, Schon SB

Clinical obstetrics and gynecology 2020; (63(2)):320-326 doi:10.1097/GRF.0000000000000510.

Expression of ALDH1A Isozymes in Human Endometrium with and without Endometriosis and in Ovarian Endometrioma.

Ma S, Hirata T, Arakawa T, et al.

Reproductive sciences (Thousand Oaks, Calif.) 2020; (27(1)):443-452 doi:10.1007/s43032-019-00041-4.

Logistic regression analyses of factors affecting fertility of intrauterine adhesions patients.

Zhao X, Liu Y, Zhang A, et al.

Annals of translational medicine 2020; (8(4)):49 doi:10.21037/atm.2019.11.115.

Meta-analysis on the use of hyaluronic acid gel to prevent intrauterine adhesion after intrauterine operations.

Zheng F, Xin X, He F, et al.

Experimental and therapeutic medicine 2020; (19(4)):2672-2678 doi:10.3892/etm.2020.8483.

Intrauterine adhesions: What is the pregnancy rate after hysteroscopic management?

Capmas P, Mihalache A, Duminil L, et al.

Journal of gynecology obstetrics and human reproduction 2020; (49(7)):101797 doi:10.1016/j.jogoh.2020.101797.

Adipose derived mesenchymal stem cell treatment in experimental asherman syndrome induced rats.

Çil N, Yaka M, Ünal MS, et al.

Molecular biology reports 2020; (47(6)):4541-4552 doi:10.1007/s11033-020-05505-4.

Asherman syndrome: Audit of a single-operator cohort of 423 cases.

Vancaillie T, Chan K, Liu J, et al.

The Australian & New Zealand journal of obstetrics & gynaecology 2020; (60(4)):574-578 doi:10.1111/ajo.13182.

The incidence of placenta related disease after the hysteroscopic adhesiolysis in patients with intrauterine adhesions.

Zhang LP, Wang M, Shang X, et al.

Taiwanese journal of obstetrics & gynecology 2020; (59(4)):575-579 doi:10.1016/j.tjog.2020.05.018.

Mini-Review of the New Therapeutic Possibilities in Asherman Syndrome-Where Are We after One Hundred and Twenty-Six Years?

Doroftei B, Dabuleanu AM, Ilie OD, et al.

Diagnostics (Basel, Switzerland) 2020; (10(9)) doi:10.3390/diagnostics10090706.

Effects of Asherman Syndrome on Maternal and Neonatal Morbidity with Evaluation by Conception Method.

Wang J, Movilla P, Morales B, et al.

Journal of minimally invasive gynecology 2021; (28(7)):1357-1366.e2 doi:10.1016/j.jmig.2020.10.004.

Identifying the risk factors and incidence of Asherman Syndrome in women with post-abortion uterine curettage.

Sevinç F, Oskovi-Kaplan ZA, Çelen Ş, et al.

The journal of obstetrics and gynaecology research 2021; (47(4)):1549-1555 doi:10.1111/jog.14667.

Linking EMT programmes to normal and neoplastic epithelial stem cells.

Lambert AW, Weinberg RA

Nature reviews. Cancer 2021; (21(5)):325-338 doi:10.1038/s41568-021-00332-6.

Patient-reported menstrual and obstetric outcomes following hysteroscopic adhesiolysis for Asherman syndrome.

Morales B, Movilla P, Wang J, et al.

F&S reports 2021; (2(1)):118-125 doi:10.1016/j.xfre.2021.01.002.

Effectiveness of Hyaluronic Acid Gel and Intrauterine Devices in Prevention of Intrauterine Adhesions after Hysteroscopic Adhesiolysis in Infertile Women.

Trinh TT, Nguyen KD, Pham HV, et al.

Journal of minimally invasive gynecology 2022; (29(2)):284-290 doi:10.1016/j.jmig.2021.08.010.

Post-hysteroscopy Duration of the Cook Balloon Uterine Stent Effect on the Re-adhesion Formation.

Qu S, Zhou P

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 2021; (31(10)):1163-1167 doi:10.29271/jcpsp.2021.10.1163.

Effect of hysteroscopic adhesiolysis on recurrence, menstruation and pregnancy outcomes in patients with different degrees of intrauterine adhesions.

Wang L, Guo C, Cao H

American journal of translational research 2022; (14(1)):484-490.

Prevalence and risk factors of intrauterine adhesions in women with a septate uterus: a retrospective cohort study.

Shen M, Duan H, Chang Y, Lin Q

Reproductive biomedicine online 2022; (44(5)):881-887 doi:10.1016/j.rbmo.2022.02.004.

Incidence and Clinical Implications of Placenta Accreta Spectrum after Treatment for Asherman Syndrome.

Tavcar J, Movilla P, Carusi DA, et al.

Journal of minimally invasive gynecology 2023; (30(3)):192-198 doi:10.1016/j.jmig.2022.11.013.

Clinical features of the predilection and severer sites of intrauterine adhesions.

Yu Y, Zou L, Li W, et al.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2022; (47(11)):1568-1574 doi:10.11817/j.issn.1672-7347.2022.220248.

hUMSCs Restore Uterine Function by Inhibiting Endometrial Fibrosis via Regulation of the MMP-9/TIMP-1 Ratio in CDDP-Induced Injury Rats.

Tang Y, Si Y, Liu C, et al.

Stem cells international 2023; (2023()):8014052 doi:10.1155/2023/8014052.

The perinatal outcomes of women treated for Asherman syndrome: a propensity score-matched cohort study.

Mára M, Borčinová M, Lisá Z, et al.

Human reproduction (Oxford, England) 2023; (38(7)):1297-1304 doi:10.1093/humrep/dead092.

Adjuvants to prevent reformation of adhesions following adhesiolysis for Asherman syndrome: a systematic review and meta-analysis.

Guo J, Shi X, Yu F, et al.

Human fertility (Cambridge, England) 2023; (26(4)):797-814 doi:10.1080/14647273.2023.2254492.

Fertility and anatomical outcomes following hysteroscopic adhesiolysis: An 11-year retrospective cohort study to validate a new classification system for intrauterine adhesions (Urman-Vitale Classification System).

Urman B, Yakin K, Ertas S, et al.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2024; (165(2)):644-654 doi:10.1002/ijgo.15262.

A retrospective cohort study to examine factors affecting live birth after hysteroscopic treatment of intrauterine adhesions.

Zhao Y, Huang X, Huang R, et al.

Fertility and sterility 2024; (121(5)):873-880 doi:10.1016/j.fertnstert.2024.01.022.

Incidence, risk factors and maternal outcomes of unsuspected placenta accreta spectrum disorders: a retrospective cohort study.

Zhao J, Li Q, Liao E, et al.

BMC pregnancy and childbirth 2024; (24(1)):76 doi:10.1186/s12884-024-06254-z.

The predictive value of serum IL-17A and IL-6 expression in postoperative recurrence in patients with intrauterine adhesion.

Cui X, Xiao HC, Pan W

American journal of reproductive immunology (New York, N.Y. : 1989) 2024; (91(1)):e13808 doi:10.1111/aji.13808.

Review of Asherman syndrome and its hysteroscopic treatment outcomes: experience in a low-resource setting.

Siferih M, Gebre T, Hunduma F, et al.

BMC women's health 2024; (24(1)):99 doi:10.1186/s12905-024-02944-0.

Value of 2D ultrasonography in the diagnosis and evaluation of intrauterine adhesions - a prospective study.

Huang R, Huang X, Li S, et al.

Reproductive biomedicine online 2024; (49(2)):103771 doi:10.1016/j.rbmo.2023.103771.

Treatment of intrauterine adhesions and subsequent pregnancy outcomes in an in vitro fertilization population.

Mortimer RM, Lanes A, Srouji SS, et al.

American journal of obstetrics and gynecology 2024; (231(5)):536.e1-536.e10 doi:10.1016/j.ajog.2024.05.026.

Reduced expression of SMAD7 and consequent reduction of autophagy promotes endometrial stromal-myofibroblast transition and fibrosis.

Yong M, Zhou H, Zeng Y, et al.

Molecular human reproduction 2024; (30(10)) doi:10.1093/molehr/gaae036.

Long-term effects of hysteroscopic adhesiolysis on postoperative pregnancy rates and fertility outcomes in patients with intrauterine adhesions.

Hu Y, Ma Y, Li W, Qu J

American journal of translational research 2024; (16(10)):5605-5613 doi:10.62347/GRAK9062.

Comparison of hysteroscopic adhesiolysis with electrosurgery instrument or hysteroscopic scissors in the treatment of intrauterine adhesions of infertile or recurrent pregnancy loss women.

Li Y, Li Y, Wang Y, et al.

Archives of gynecology and obstetrics 2025; (311(4)):1063-1071 doi:10.1007/s00404-024-07866-8.

Extended intrauterine balloon stent use to prevent adhesion reformation after hysteroscopic adhesiolysis: a randomized trial.

Luo Y, Liu Y, Xiao Y, et al.

Fertility and sterility 2025; (124(1)):144-152 doi:10.1016/j.fertnstert.2025.01.024.

Comparative Analysis of Hysterosalpingography and Diagnostic Hysteroscopy Findings in Infertility Evaluation.

G M, M S

Cureus 2025; (17(4)):e81789 doi:10.7759/cureus.81789.

Optimal timing of hysteroscopic follow-up to prevent the recurrence of intrauterine adhesions: a retrospective study.

Dao S, Zhang L, Liu C, et al.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 2025; (45(1)):2500970 doi:10.1080/01443615.2025.2500970.

Efficacy of high-dose estrogen and progesterone sequential assisted hysteroscopic cold knife separation versus hysteroscopic cold knife separation alone in the treatment of infertility or amenorrhea caused by severe intrauterine adhesion: a retrospective cohort study.

Wang X, Han J, Song Y

BMC surgery 2025; (25(1)):246 doi:10.1186/s12893-025-02964-z.

"The threat of Asherman syndrome": a propensity score-matched study of fetal-maternal outcomes.

Hanstede MMF, Veersema S, Emanuel MH, et al.

Fertility and sterility 2025; (124(5 Pt 2)):1104-1114 doi:10.1016/j.fertnstert.2025.06.027.

XBP1 promotes endometrial fibrosis through cGAS-STING signaling pathway in intrauterine adhesion.

Wu X, He L, Lin Y, et al.

Scientific reports 2025; (15(1)):23299 doi:10.1038/s41598-025-06162-y.

Single-cell sequencing uncovers disrupted stromal-macrophage communication as a driver of intrauterine adhesion progression.

Dong E, Zhou Z, Chen T, et al.

Communications biology 2025; (8(1)):1194 doi:10.1038/s42003-025-08634-3.

Determinants of uterine synechiae at hysteroscopy: a case-control study in Kinshasa, Democratic Republic of Congo.

Nzau-Ngoma E, Lumingu AL, Mindombe PM, et al.

The Pan African medical journal 2025; (51()):64 doi:10.11604/pamj.2025.51.64.43555.

A randomized clinical trial of surgical intervention with or without acupuncture combined with traditional Chinese medicine to treat intrauterine adhesions.

Wenwen Z, Jiaqi W, Jing S, et al.

Contemporary clinical trials communications 2025; (48()):101565 doi:10.1016/j.conctc.2025.101565.

Diagnostic accuracy of three-dimensional transvaginal ultrasound for intrauterine adhesions: a systematic review and meta-analysis.

Huang L, Huang Z, Hu B

Frontiers in medicine 2025; (12()):1690719 doi:10.3389/fmed.2025.1690719.

Incidence and Risk Factors for Intrauterine Synechiae in Women With Previous Dilation and Curettage.

Chen S, Samiezade-Yazd Z, Triplett C, Joshi N

Obstetrics and gynecology 2026; (147(3)):366-373 doi:10.1097/AOG.0000000000006158.

Treatment Outcomes of Individualized PDLLA-Copper Stents Versus Intrauterine Balloons in Moderate-to-Severe Intrauterine Adhesions After Hysteroscopic Adhesiolysis: A Propensity Score-Weighted Analysis.

Zhao K, Tang S, Zhang F, et al.

Journal of minimally invasive gynecology 2026; doi:10.1016/j.jmig.2026.01.010.