Research & Literature

Reverse cardiac remodeling after renal denervation: Atrial electrophysiologic and structural changes associated with blood pressure lowering.

McLellan AJ, Schlaich MP, Taylor AJ, et al.

Heart rhythm 2015; (12(5)):982-90.

Dual-chamber pacemakers for treating symptomatic bradycardia due to sick sinus syndrome without atrioventricular block: a systematic review and economic evaluation.

Edwards SJ, Karner C, Trevor N, et al.

Health technology assessment (Winchester, England) 2015; (19(65)):1-210 doi:10.3310/hta19650.

Cardiac pacing strategies and post-implantation risk of atrial fibrillation and heart failure events in sinus node dysfunction patients: a collaborative analysis of over 6000 patients.

Chen S, Wang Z, Kiuchi MG, et al.

Clinical research in cardiology : official journal of the German Cardiac Society 2016; (105(8)):687-698 doi:10.1007/s00392-016-0973-1.

Electrocardiographic Advanced Interatrial Block and Atrial Fibrillation Risk in the General Population.

O'Neal WT, Zhang ZM, Loehr LR, et al.

The American journal of cardiology 2016; (117(11)):1755-9.

[Bradyarrhythmias: diagnostics].

Israel CW

Deutsche medizinische Wochenschrift (1946) 2016; (141(10)):718-28 doi:10.1055/s-0042-103296.

CHADS2 and CHA2DS2-VASc Scores Predict the Risk of Ischemic Stroke Outcome in Patients with Interatrial Block without Atrial Fibrillation.

Wu JT, Wang SL, Chu YJ, et al.

Journal of atherosclerosis and thrombosis 2017; (24(2)):176-184 doi:10.5551/jat.34900.

Electrophysiological Mechanisms of Bayés Syndrome: Insights from Clinical and Mouse Studies.

Tse G, Lai ET, Yeo JM, Yan BP

Frontiers in physiology 2016; (7()):188 doi:10.3389/fphys.2016.00188.

Advanced interatrial block and ischemic stroke: The Atherosclerosis Risk in Communities Study.

O'Neal WT, Kamel H, Zhang ZM, et al.

Neurology 2016; (87(4)):352-6 doi:10.1212/WNL.0000000000002888.

Assessment of atrial fibrosis for the rhythm control of atrial fibrillation.

Begg GA, Holden AV, Lip GY, et al.

International journal of cardiology 2016; (220()):155-61.

Signal Transducer and Activator of Transcription 3/MicroRNA-21 Feedback Loop Contributes to Atrial Fibrillation by Promoting Atrial Fibrosis in a Rat Sterile Pericarditis Model.

Huang Z, Chen XJ, Qian C, et al.

Circulation. Arrhythmia and electrophysiology 2016; (9(7)).

Bradyarrhythmias: Clinical Presentation, Diagnosis, and Management.

Wung SF

Critical care nursing clinics of North America 2016; (28(3)):297-308.

Interatrial block predicts atrial high rate episodes detected by cardiac implantable electronic devices.

Tekkesin AI, Çinier G, Cakilli Y, et al.

Journal of electrocardiology 2017; (50(2)):234-237 doi:10.1016/j.jelectrocard.2016.09.004.

Left Atrial Enlargement on Transthoracic Echocardiography Predicts Left Atrial Thrombus on Transesophageal Echocardiography in Ischemic Stroke Patients.

Anaissie J, Monlezun D, Seelochan A, et al.

BioMed research international 2016; (2016()):7194676 doi:10.1155/2016/7194676.

Sinus Node Dysfunction and Atrial Fibrillation: A Reversible Phenomenon?

Jackson LR, Rathakrishnan B, Campbell K, et al.

Pacing and clinical electrophysiology : PACE 2017; (40(4)):442-450 doi:10.1111/pace.13030.

Effect of Aggressive Blood Pressure Control on the Recurrence of Atrial Fibrillation After Catheter Ablation: A Randomized, Open-Label Clinical Trial (SMAC-AF [Substrate Modification With Aggressive Blood Pressure Control]).

Parkash R, Wells GA, Sapp JL, et al.

Circulation 2017; (135(19)):1788-1798 doi:10.1161/CIRCULATIONAHA.116.026230.

Bayes Syndrome and Imaging Techniques.

Hernandez-Betancor I, Izquierdo-Gomez MM, Garcia-Niebla J, et al.

Current cardiology reviews 2017; (13(4)):263-273 doi:10.2174/1573403X13666170713122600.

Symptomatic Long Pauses and Bradycardia due to Massive Multinodular Goiter.

Deshmukh A, Ozcan C

Case reports in cardiology 2017; (2017()):4201942 doi:10.1155/2017/4201942.

[Sinus bradycardia and syncope: what pathophysiological mechanism and what management of the patient?]

Alboni P, Stucci N, Parisi C

Giornale italiano di cardiologia (2006) 2017; (18(11)):774-780 doi:10.1714/2803.28363.

Atrial Substrate and Triggers of Paroxysmal Atrial Fibrillation in Patients With Obstructive Sleep Apnea.

Anter E, Di Biase L, Contreras-Valdes FM, et al.

Circulation. Arrhythmia and electrophysiology 2017; (10(11)) doi:10.1161/CIRCEP.117.005407.

Atrioventricular Interval Extension Is Highly Efficient in Preventing Unnecessary Right Ventricular Pacing in Sinus Node Disease: A Randomized Cross-Over Study Versus Dual- to Atrial Single-Chamber Mode Switch.

Calvi V, Pisanò EC, Brieda M, et al.

JACC. Clinical electrophysiology 2017; (3(5)):482-490 doi:10.1016/j.jacep.2016.11.011.

Sick Sinus Syndrome.

De Ponti R, Marazzato J, Bagliani G, et al.

Cardiac electrophysiology clinics 2018; (10(2)):183-195 doi:10.1016/j.ccep.2018.02.002.

Risk Prediction of Atrial Fibrillation Based on Electrocardiographic Interatrial Block.

Skov MW, Ghouse J, Kühl JT, et al.

Journal of the American Heart Association 2018; (7(11)) doi:10.1161/JAHA.117.008247.

A case of atenolol-induced sinus node dysfunction presenting as escape-capture bigeminy.

Manne JRR

Oxford medical case reports 2018; (2018(5)):omy015 doi:10.1093/omcr/omy015.

PREVEntion and regReSsive Effect of weight-loss and risk factor modification on Atrial Fibrillation: the REVERSE-AF study.

Middeldorp ME, Pathak RK, Meredith M, et al.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2018; (20(12)):1929-1935 doi:10.1093/europace/euy117.

Intra- and interatrial conduction abnormalities: hemodynamic and arrhythmic significance.

Johner N, Namdar M, Shah DC

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 2018; (52(3)):293-302 doi:10.1007/s10840-018-0413-4.

The Diagnosis and Clinical Implications of Interatrial Block.

de Luna AB, Massó-van Roessel A, Robledo LAE

European cardiology 2015; (10(1)):54-59 doi:10.15420/ecr.2015.10.01.54.

Evaluating and managing bradycardia.

Sidhu S, Marine JE

Trends in cardiovascular medicine 2020; (30(5)):265-272 doi:10.1016/j.tcm.2019.07.001.

Myxedema coma accompanied by sick sinus syndrome and hypoventilation: A case report.

Harada K, Murakami S, Tokumasu K, et al.

Journal of general and family medicine 2019; (20(5)):206-208 doi:10.1002/jgf2.267.

Meta-analysis of Effect of Modest (≥10%) Weight Loss in Management of Overweight and Obese Patients With Atrial Fibrillation.

Aldaas OM, Lupercio F, Han FT, et al.

The American journal of cardiology 2019; (124(10)):1568-1574 doi:10.1016/j.amjcard.2019.08.009.

Advanced interatrial block: A predictor of covert atrial fibrillation in embolic stroke of undetermined source.

Mendieta G, Guasch E, Weir D, et al.

Journal of electrocardiology 2020; (58()):113-118 doi:10.1016/j.jelectrocard.2019.11.050.

Alcohol Abstinence in Drinkers with Atrial Fibrillation.

Voskoboinik A, Kalman JM, De Silva A, et al.

The New England journal of medicine 2020; (382(1)):20-28 doi:10.1056/NEJMoa1817591.

Usefulness of an Implantable Loop Recorder in Diagnosing Unexplained Syncope and Predictors for Pacemaker Implantation.

Lee SH, Kim TH, Oh YS, et al.

Journal of Korean medical science 2020; (35()):e11 doi:10.3346/jkms.2020.35.e11.

The prevalence and prognostic significance of interatrial block in the general population.

Istolahti T, Eranti A, Huhtala H, et al.

Annals of medicine 2020; (52(3-4)):63-73 doi:10.1080/07853890.2020.1731759.

Comprehensive Evaluation of Rhythm Monitoring Strategies in Screening for Atrial Fibrillation: Insights From Patients at Risk Monitored Long Term With an Implantable Loop Recorder.

Diederichsen SZ, Haugan KJ, Kronborg C, et al.

Circulation 2020; (141(19)):1510-1522 doi:10.1161/CIRCULATIONAHA.119.044407.

Relation of Advanced Interatrial Block to Risk of Atrial Fibrillation and Stroke.

Bayés-de-Luna A, Martínez-Sellés M, Elosua R, et al.

The American journal of cardiology 2020; (125(11)):1745-1748 doi:10.1016/j.amjcard.2020.02.034.

Advanced interatrial block and P-wave duration are associated with atrial fibrillation and stroke in older adults with heart disease: the BAYES registry.

Martínez-Sellés M, Elosua R, Ibarrola M, et al.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2020; (22(7)):1001-1008 doi:10.1093/europace/euaa114.

Impact of risk-factor modification on arrhythmia recurrence among morbidly obese patients undergoing atrial fibrillation ablation.

Donnellan E, Wazni OM, Kanj M, et al.

Journal of cardiovascular electrophysiology 2020; (31(8)):1979-1986 doi:10.1111/jce.14607.

What every clinician should know about Bayés syndrome.

Bayés de Luna A, Martínez-Sellés M, Bayés-Genís A, et al.

Revista espanola de cardiologia (English ed.) 2020; (73(9)):758-762 doi:10.1016/j.rec.2020.04.026.

Prevalence of Undiagnosed Sleep Apnea in Patients With Atrial Fibrillation and its Impact on Therapy.

Shapira-Daniels A, Mohanty S, Contreras-Valdes FM, et al.

JACC. Clinical electrophysiology 2020; (6(12)):1499-1506 doi:10.1016/j.jacep.2020.05.030.

A rare combination of atrial and intraventricular conduction disturbances: Atypical type I advanced interatrial block, left posterior fascicular block and transient right bundle branch block.

Manzzardo J, Barbosa-Barros R, Nikus K, Pérez-Riera AR

Journal of electrocardiology 2021; (65()):45-49 doi:10.1016/j.jelectrocard.2020.12.004.

Resumption of interatrial conduction after atrial premature beat in baseline interatrial aberrancy.

Rungpradubvong V

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 2021; (26(6)):e12838 doi:10.1111/anec.12838.

Genetic Complexity of Sinoatrial Node Dysfunction.

Wallace MJ, El Refaey M, Mesirca P, et al.

Frontiers in genetics 2021; (12()):654925 doi:10.3389/fgene.2021.654925.

Sinus Node Dysfunction.

Sathnur N, Ebin E, Benditt DG

Cardiac electrophysiology clinics 2021; (13(4)):641-659 doi:10.1016/j.ccep.2021.06.006.

Electrocardiographic predictors of atrial fibrillation in patients with cryptogenic stroke.

de Leon A, Neira V, Alhammad N, et al.

Pacing and clinical electrophysiology : PACE 2022; (45(2)):176-181 doi:10.1111/pace.14418.

Sinus node exit, crista terminalis conduction, interatrial connection, and wavefront collision: Key features of human atrial activation in sinus rhythm.

Pambrun T, Derval N, Duchateau J, et al.

Heart rhythm 2022; (19(5)):701-709 doi:10.1016/j.hrthm.2022.01.016.

Impact of CPAP on the Atrial Fibrillation Substrate in Obstructive Sleep Apnea: The SLEEP-AF Study.

Nalliah CJ, Wong GR, Lee G, et al.

JACC. Clinical electrophysiology 2022; (8(7)):869-877 doi:10.1016/j.jacep.2022.04.015.

European Stroke Organisation (ESO) guideline on screening for subclinical atrial fibrillation after stroke or transient ischaemic attack of undetermined origin.

Rubiera M, Aires A, Antonenko K, et al.

European stroke journal 2022; (7(3)):VI doi:10.1177/23969873221099478.

Severe functional tricuspid regurgitation due to wild-type transthyretin amyloid cardiomyopathy without left ventricular hypertrophy: a case report.

Matsuzoe H, Tanaka H, Sato S, Otani K

European heart journal. Case reports 2022; (6(12)):ytac462 doi:10.1093/ehjcr/ytac462.

Effect of continuous positive airway pressure on atrial remodeling and diastolic dysfunction of patients with obstructive sleep apnea and metabolic syndrome: a randomized study.

Macedo TA, Giampá SQC, Furlan SF, et al.

Obesity (Silver Spring, Md.) 2023; (31(4)):934-944 doi:10.1002/oby.23699.

Avoiding unnecessary ventricular pacing is associated with reduced incidence of heart failure hospitalizations and persistent atrial fibrillation in pacemaker patients.

Arnold M, Richards M, D'Onofrio A, et al.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2023; (25(5)) doi:10.1093/europace/euad065.

A Case of Sick Sinus Syndrome With Prolonged Asystole Masquerading as a Transient Ischemic Attack.

Rathore A, Gupta N, Wu E, et al.

Cureus 2023; (15(2)):e35465 doi:10.7759/cureus.35465.

Association between sick sinus syndrome and atrial fibrillation: A systematic review and meta-analysis.

Liu Y, Zheng Y, Tse G, et al.

International journal of cardiology 2023; (381()):20-36 doi:10.1016/j.ijcard.2023.03.066.

P-wave duration and interatrial block as predictors of new-onset atrial fibrillation: A systematic review and meta-analysis.

Zagoridis K, Koutalas E, Intzes S, et al.

Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 2023; (72()):57-64 doi:10.1016/j.hjc.2023.03.007.

Sinus Node Dysfunction.

Sathnur N, Ebin E, Benditt DG

Cardiology clinics 2023; (41(3)):349-367 doi:10.1016/j.ccl.2023.03.013.

Interatrial Block Association With Adverse Cardiovascular Outcomes in Patients Without a History of Atrial Fibrillation.

Lampert J, Power D, Havaldar S, et al.

JACC. Clinical electrophysiology 2023; (9(8 Pt 3)):1804-1815 doi:10.1016/j.jacep.2023.04.006.

Management of mad honey intoxication with suspected anaphylaxis in Nepal: a case report.

Anand A, Adhikari N, Gupta A, et al.

Annals of medicine and surgery (2012) 2023; (85(6)):3075-3078 doi:10.1097/MS9.0000000000000800.

Mechanisms of Atrial Fibrillation in Obstructive Sleep Apnoea.

Saleeb-Mousa J, Nathanael D, Coney AM, et al.

Cells 2023; (12(12)) doi:10.3390/cells12121661.

Predicting risk of AF in ischaemic stroke using sinus rhythm ECG abnormalities: A meta-analysis.

Berry-Noronha A, Bonavia L, Wilson D, et al.

European stroke journal 2023; (8(3)):712-721 doi:10.1177/23969873231172559.

Tachy-brady syndrome: Electrophysiology and evolving principles of management.

Padda I, Sebastian SA, Khehra N, et al.

Disease-a-month : DM 2024; (70(2)):101637 doi:10.1016/j.disamonth.2023.101637.

The Role of Electrocardiographic Markers for Predicting Atrial Fibrillation in Patients with Acute Ischemic Stroke: Data from the BIOSIGNAL Cohort Study.

Schütz V, Dougoud S, Bracher K, et al.

Journal of clinical medicine 2023; (12(21)) doi:10.3390/jcm12216830.

Interatrial Block, Bayés Syndrome, Left Atrial Enlargement, and Atrial Failure.

Bejarano-Arosemena R, Martínez-Sellés M

Journal of clinical medicine 2023; (12(23)) doi:10.3390/jcm12237331.

Cardiovascular Disease: Other Common Arrhythmias.

Guess JM, Gauer RL

FP essentials 2024; (536()):22-28.

Multimodal Cardiac Imaging in the Assessment of Patients Who Have Suffered a Cardioembolic Stroke: A Review.

Thong EHE, Kong WKF, Poh KK, et al.

Journal of cardiovascular development and disease 2023; (11(1)) doi:10.3390/jcdd11010013.

Incidental Arrhythmias During Atrial Fibrillation Screening With Repeat 7-Day Holter ECGs in a Hospital-Based Patient Population.

Goulouti E, Lam A, Nozica N, et al.

Journal of the American Heart Association 2024; (13(4)):e032223 doi:10.1161/JAHA.123.032223.

Severe Sinus Dysfunction in the Context of Chronic Lithium Intoxication and Poorly Controlled Hypothyroidism.

Ardila CM, López-Valencia A, González-Arroyave D

Cureus 2024; (16(2)):e55127 doi:10.7759/cureus.55127.

Sleep-Disordered Breathing and Cardiac Arrhythmias.

Menon T, Ogbu I, Kalra DK

Journal of clinical medicine 2024; (13(22)) doi:10.3390/jcm13226635.

Panhypopituitarism presenting as sick sinus syndrome: A case series.

Rajakumar P, Sheya A, Asirvatham AR, et al.

JPMA. The Journal of the Pakistan Medical Association 2025; (75(5)):819-822 doi:10.47391/JPMA.11523.

Atrial fibrillation with slow-ventricular response (AF-SVR): A literature review.

Choi J, Kong D, Katic L, et al.

The journal of medicine access 2025; (9()):27550834251342890 doi:10.1177/27550834251342890.

Detection rate by time period and predictors of serious arrhythmias in unexplained syncope: a multicenter implantable loop recorder registry study.

Kim J, Oh IY, Cha MJ, et al.

The Korean journal of internal medicine 2025; (40(4)):616-625 doi:10.3904/kjim.2024.364.

A Patch-Type Electrocardiography Is Superior to Holter Monitoring for Detecting Paroxysmal Cardiac Arrhythmias.

Kim YG, Choi JI, Oh IY, et al.

Journal of Korean medical science 2025; (40(28)):e168 doi:10.3346/jkms.2025.40.e168.

Interatrial Block Detected by a Series of ECGs Before and During Acute Coronary Syndrome Predicts Atrial Fibrillation, Atrial Flutter, and Ischemic Stroke.

Aarnivala V, Istolahti T, Hurskainen M, et al.

Journal of the American Heart Association 2025; (14(20)):e041313 doi:10.1161/JAHA.125.041313.

Association of Atrial Electrophysiological Abnormalities With Cognitive Decline and Cerebrovascular Disease.

Tan ESJ, Sim MA, Li L, et al.

Journal of the American Heart Association 2026; (15(1)):e045054 doi:10.1161/JAHA.125.045054.

Prevalence of clinically significant bradyarrhythmias in patients implanted with loop recorders for cryptogenic stroke: A manifestation of atrial cardiomyopathy?

Bencardino G, Festa PA, Scacciavillani R, et al.

Heart rhythm 2026; (23(4)):e653-e658 doi:10.1016/j.hrthm.2026.01.011.

Reversible sick sinus syndrome due to sinus node artery ischaemia in an elderly woman: a case report.

Kaneko Y, Hitsumoto T, Tada M, et al.

European heart journal. Case reports 2026; (10(1)):ytaf660 doi:10.1093/ehjcr/ytaf660.

Real-world use of theophylline in critically ill patients with sinus pauses: a case series.

Elahi MA, Jalal H, Frick W, Kraft BD

Frontiers in cardiovascular medicine 2026; (13()):1731993 doi:10.3389/fcvm.2026.1731993.

Fundamental Anatomy and its Impact on Clinical Practice: Bachmann's Bundle and Interatrial Conduction (Part I-III).

González-Casal D, Baranchuk A, Sánchez-Quintana D, Cabrera JÁ

JACC. Case reports 2026; (31(17)):107414 doi:10.1016/j.jaccas.2026.107414.

Temporary Rhythm Control with Flecainide in Atrial Fibrillation-Related Conversion Pauses Prior to Catheter Ablation: A Case of Successful Pharmacological Bridging.

Skakun O, Varunkiv O, Symchych A, et al.

International medical case reports journal 2026; (19()):604692 doi:10.2147/IMCRJ.S604692.

The cardiac conduction system: A narrative review.

Kariman M, Pretterklieber B, Pretterklieber ML, et al.

Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2026; (268()):152880 doi:10.1016/j.aanat.2026.152880.

An Abrupt Doubling of Heart Rate.

Kawji MM

JACC. Case reports 2026; (31(30)):109304 doi:10.1016/j.jaccas.2026.109304.

[Atrial fibrillation screening-reading the P-wave].

Wiedmann F, Weitkamp FM, Schmidt C

Innere Medizin (Heidelberg, Germany) 2026; doi:10.1007/s00108-026-02193-3.