Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
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National Jewish Health
Denver, United States
Université Claude Bernard Lyon 1
Villeurbanne, France
Brigham and Women's Hospital
Boston, United States
University of Colorado Anschutz Medical Campus
Aurora, United States
McMaster University
Hamilton, Canada
Mayo Clinic
Rochester, United States
University of Chicago
Chicago, United States
University of Michigan
Ann Arbor, United States
Royal Brompton Hospital
London, United Kingdom
Inserm
Paris, France
References
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Systematic review and meta-analysis of the risk of rheumatoid arthritis-associated interstitial lung disease related to anti-cyclic citrullinated peptide (CCP) antibody.
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Clinical characteristics of interstitial lung diseases positive to different anti-synthetase antibodies.
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High-Resolution CT Findings of Myositis-Related Interstitial Lung Disease.
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Role of autoantibodies in the diagnosis and prognosis of interstitial lung disease in autoimmune rheumatic disorders.
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Management of MDA-5 antibody positive clinically amyopathic dermatomyositis associated interstitial lung disease: A systematic review.
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Seminars in arthritis and rheumatism 2022; (53()):151959 doi:10.1016/j.semarthrit.2022.151959.
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Pathogenesis of Anti-melanoma Differentiation-Associated Gene 5 Antibody-Positive Dermatomyositis: A Concise Review With an Emphasis on Type I Interferon System.
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Arthritis & rheumatology (Hoboken, N.J.) 2022; (74(6)):1039-1047 doi:10.1002/art.42075.
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Interstitial Pneumonia with Autoimmune Features: What the Rheumatologist Needs to Know.
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Identification and Prognosis of Patients With Interstitial Pneumonia With Autoimmune Features.
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Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 2022; (28(5)):257-264 doi:10.1097/RHU.0000000000001847.
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Immunomodulatory treatment of interstitial lung disease.
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The Role of Myositis-Specific Autoantibodies and the Management of Interstitial Lung Disease in Idiopathic Inflammatory Myopathies: A Systematic Review.
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Seminars in arthritis and rheumatism 2022; (57()):152088 doi:10.1016/j.semarthrit.2022.152088.
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Analysis of the clinical features of antisynthetase syndrome: a retrospective cohort study in China.
Wang R, Zhao Y, Qi F, et al.
Clinical rheumatology 2023; (42(3)):703-709 doi:10.1007/s10067-022-06404-8.
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CT predictors of outcomes in patients with connective tissue disease and progressive lung fibrosis.
Shou AY, Salvatore MM
Clinical imaging 2023; (94()):42-49 doi:10.1016/j.clinimag.2022.11.022.
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Interstitial Lung Disease: A Focused Review for the Emergency Clinician.
Constantino K, Gottlieb M, Long B
The Journal of emergency medicine 2023; (64(2)):156-166 doi:10.1016/j.jemermed.2022.10.015.
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Effect of nintedanib in patients with progressive pulmonary fibrosis associated with rheumatoid arthritis: data from the INBUILD trial.
Matteson EL, Aringer M, Burmester GR, et al.
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Predictive factors for anti-MDA5 antibody in patients with dermatomyositis: a retrospective multicenter study.
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Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2023; (21(7)):741-748 doi:10.1111/ddg.15089.
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Rituximab and mycophenolate mofetil combination in patients with interstitial lung disease (EVER-ILD): a double-blind, randomised, placebo-controlled trial.
Mankikian J, Caille A, Reynaud-Gaubert M, et al.
The European respiratory journal 2023; (61(6)) doi:10.1183/13993003.02071-2022.
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Learnings from clinical trials in patients with connective tissue disease-associated interstitial lung disease.
Higuero Sevilla JP, Memon A, Hinchcliff M
Arthritis research & therapy 2023; (25(1)):118 doi:10.1186/s13075-023-03090-y.
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Myositis-associated interstitial lung disease.
Vu TTT, Brown KK, Solomon JJ
Current opinion in pulmonary medicine 2023; (29(5)):427-435 doi:10.1097/MCP.0000000000001000.
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New therapies in anti-MDA5 antibody-positive dermatomyositis.
Yasui M, Iwamoto T, Furuta S
Current opinion in rheumatology 2024; (36(1)):61-68 doi:10.1097/BOR.0000000000000979.
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Treatment of Systemic Sclerosis-associated Interstitial Lung Disease: Evidence-based Recommendations. An Official American Thoracic Society Clinical Practice Guideline.
Raghu G, Montesi SB, Silver RM, et al.
American journal of respiratory and critical care medicine 2024; (209(2)):137-152 doi:10.1164/rccm.202306-1113ST.
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Mycophenolate mofetil versus cyclophosphamide plus in patients with connective tissue disease-associated interstitial lung disease: Efficacy and safety analysis.
Wang P, Zhang L, Guo Q, et al.
Open medicine (Warsaw, Poland) 2023; (18(1)):20230838 doi:10.1515/med-2023-0838.
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Antibody predictors of mortality and lung function trends in myositis spectrum interstitial lung disease.
Hannah JR, Lawrence A, Martinovic J, et al.
Rheumatology (Oxford, England) 2024; (63(11)):3080-3090 doi:10.1093/rheumatology/kead638.
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Comparison of characteristics and anti-MDA5 antibody distribution and effect between clinically amyopathic dermatomyositis and classic dermatomyositis: a retrospective case-control study.
Ji Q, Pan W, Zhang D, et al.
Frontiers in immunology 2023; (14()):1237209 doi:10.3389/fimmu.2023.1237209.
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Progressive Pulmonary Fibrosis: Where Are We Now?
Kang HK, Song JW
Tuberculosis and respiratory diseases 2024; (87(2)):123-133 doi:10.4046/trd.2023.0119.
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A Case of Dermatomyositis with Coexistence of Positive Anti-MDA5 Antibodies and Anti-SSA/RO52 Antibodies, Combined with Necrotic Skin Ulcers.
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International medical case reports journal 2024; (17()):9-15 doi:10.2147/IMCRJ.S441691.
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Lung imaging patterns in connective tissue disease-associated interstitial lung disease impact prognosis and immunosuppression response.
Zheng B, Marinescu DC, Hague CJ, et al.
Rheumatology (Oxford, England) 2024; (63(10)):2734-2740 doi:10.1093/rheumatology/keae076.
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Interstitial Lung Disease: A Review.
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JAMA 2024; (331(19)):1655-1665 doi:10.1001/jama.2024.3669.
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A Review of Antisynthetase Syndrome-Associated Interstitial Lung Disease.
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International journal of molecular sciences 2024; (25(8)) doi:10.3390/ijms25084453.
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Review of Pulmonary Manifestations in Antisynthetase Syndrome.
Ghanbar MI, Danoff SK
Seminars in respiratory and critical care medicine 2024; (45(3)):365-385 doi:10.1055/s-0044-1785536.
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Imaging in the diagnosis and management of fibrosing interstitial lung diseases.
Lederer C, Storman M, Tarnoki AD, et al.
Breathe (Sheffield, England) 2024; (20(1)):240006 doi:10.1183/20734735.0006-2024.
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Prognostic analysis of MDA5-associated clinically amyopathic dermatomyositis with interstitial lung disease.
Wang W, Sun X, Xu Y, et al.
Immunity, inflammation and disease 2024; (12(6)):e1332 doi:10.1002/iid3.1332.
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Identification and management of interstitial lung disease associated with systemic sclerosis (SSc-ILD), rheumatoid arthritis (RA-ILD), and polymyositis/dermatomyositis (PM/DM-ILD): development of expert consensus-based clinical algorithms.
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Expert review of respiratory medicine 2024; (18(6)):447-456 doi:10.1080/17476348.2024.2374910.
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2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Screening and Monitoring of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases.
Johnson SR, Bernstein EJ, Bolster MB, et al.
Arthritis care & research 2024; (76(8)):1070-1082 doi:10.1002/acr.25347.
PMID: 38973729 - 75
2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Treatment of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases.
Johnson SR, Bernstein EJ, Bolster MB, et al.
Arthritis care & research 2024; (76(8)):1051-1069 doi:10.1002/acr.25348.
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Antifibrotic therapy in progressive pulmonary fibrosis: a review of recent advances.
Naqvi M, Hannah J, Lawrence A, et al.
Expert review of respiratory medicine 2024; (18(6)):397-407 doi:10.1080/17476348.2024.2375420.
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Asymptomatic and slowly progressive anti-MDA5 ILD: A report of three cases deviating from a notoriously rapidly progressive ILD.
Puthumana RM, Koch AL, Schettino C, Vehar SJ
Respiratory medicine case reports 2024; (51()):102072 doi:10.1016/j.rmcr.2024.102072.
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Value of bronchoalveolar lavage fluid metagenomic next-generation sequencing in acute exacerbation of fibrosing interstitial lung disease: an individualized treatment protocol based on microbiological evidence.
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BMC pulmonary medicine 2024; (24(1)):400 doi:10.1186/s12890-024-03216-1.
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Impact of Sex, Serostatus, and Smoking on Risk for Rheumatoid Arthritis-Associated Interstitial Lung Disease Subtypes.
McDermott GC, Hayashi K, Juge PA, et al.
Arthritis care & research 2025; (77(2)):185-194 doi:10.1002/acr.25432.
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Treatment of rheumatoid arthritis-associated interstitial lung disease: An appraisal of the 2023 ACR/CHEST guideline.
Saavedra AA, Mueller KT, Kowalski EN, et al.
Current treatment options in rheumatology 2024; (10(4)):43-60 doi:10.1007/s40674-024-00217-3.
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Clinical Characteristics and Outcomes of Patients with Anti-MDA5 Antibody Associated Rapidly Progressive Interstitial Lung Disease (RP-ILD): A Case Series.
Gangadharan H, Seetha AP, Musthafa S, et al.
Mediterranean journal of rheumatology 2024; (35(4)):668-679 doi:10.31138/mjr.020324.cco.
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Validation of a semi-quantitative method to assess interstitial lung disease severity and progression in systemic sclerosis by standard and low-dose HRCT scans.
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RMD open 2025; (11(1)) doi:10.1136/rmdopen-2024-004938.
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Total lung capacity is predictive of disease severity and survival in systemic sclerosis: A longitudinal analysis in 2347 patients from the French National Cohort Study.
Chaigne B, Bense A, Aubourg F, et al.
Journal of autoimmunity 2025; (152()):103391 doi:10.1016/j.jaut.2025.103391.
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Development of a prediction model for progression of rheumatoid arthritis-associated interstitial lung disease using serologic and clinical factors: The prospective KORAIL cohort.
Chang SH, Paudel ML, McDermott GC, et al.
Seminars in arthritis and rheumatism 2025; (73()):152729 doi:10.1016/j.semarthrit.2025.152729.
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Procalcitonin in acute exacerbation of interstitial lung disease: A systematic review of current evidence.
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[Connective tissue disease-associated interstitial lung diseases : A pattern-based approach to diagnosis].
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ERS/EULAR clinical practice guidelines for connective tissue disease-associated interstitial lung disease.
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The European respiratory journal 2026; (67(1)) doi:10.1183/13993003.02533-2024.
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High-Resolution CT Findings in Interstitial Lung Disease Associated with Connective Tissue Diseases: Differentiating Patterns for Clinical Practice-A Systematic Review with Meta-Analysis.
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Journal of clinical medicine 2025; (14(17)) doi:10.3390/jcm14176164.
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Longitudinal change of idiopathic inflammatory myopathy-associated interstitial lung disease on high-resolution computed tomography, a prospective cohort study.
Qiang Y, Wang H, Ni Y, et al.
BMC pulmonary medicine 2025; (25(1)):503 doi:10.1186/s12890-025-03962-w.
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The importance of considering progression speed in systemic sclerosis-associated interstitial lung diseases: application of 2022 and 2024 clinical practice guidelines for progressive pulmonary fibrosis, a retrospective cohort study.
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