Research & Literature

Early central diabetes insipidus: An ominous sign in post-cardiac arrest patients.

Chae MK, Lee JH, Lee TR, et al.

Journal of critical care 2016; (32()):63-7.

Animal models of Central Diabetes Insipidus: Human relevance of acquired beyond hereditary syndromes and the role of oxytocin.

Bernal A, Mahía J, Puerto A

Neuroscience and biobehavioral reviews 2016; (66()):1-14.

Diabetes insipidus in infants and children.

Dabrowski E, Kadakia R, Zimmerman D

Best practice & research. Clinical endocrinology & metabolism 2016; (30(2)):317-28.

Oral administration of diluted nasal desmopressin in managing neonatal central diabetes insipidus.

Mavinkurve M, McGrath N, Johnston N, et al.

Journal of pediatric endocrinology & metabolism : JPEM 2017; (30(6)):623-628.

Congenital nephrogenic diabetes insipidus in the Corpus Hippocraticum: The first description.

Tsoucalas G, Karamanou M

Hormones (Athens, Greece) 2017; (16(2)):209-211 doi:10.14310/horm.2002.1736.

Transient Central Diabetes Insipidus and Marked Hypernatremia following Cardiorespiratory Arrest.

Koubar SH, Younes E

Case reports in nephrology 2017; (2017()):1574625 doi:10.1155/2017/1574625.

Time for change: Renaming Diabetes Insipidus to improve patient safety.

Prentice M

Clinical endocrinology 2018; (88(5)):625-626 doi:10.1111/cen.13578.

[Clinical characteristics of central diabetes insipidus: a retrospective analysis of 230 cases].

Zhang JP, Guo QH, Mu YM, et al.

Zhonghua nei ke za zhi 2018; (57(3)):201-205 doi:10.3760/cma.j.issn.0578-1426.2018.03.010.

Desmopressin-Induced Severe Hyponatremia with Central Pontine Myelinolysis: A Case Report.

Hossain T, Ghazipura M, Reddy V, et al.

Drug safety - case reports 2018; (5(1)):19 doi:10.1007/s40800-018-0084-1.

A Copeptin-Based Approach in the Diagnosis of Diabetes Insipidus.

Fenske W, Refardt J, Chifu I, et al.

The New England journal of medicine 2018; (379(5)):428-439 doi:10.1056/NEJMoa1803760.

Triphasic response of pituitary stalk injury following TBI: a relevant yet uncommonly recognised endocrine phenomenon.

Goel A, Farhat F, Zik C, Jeffery M

BMJ case reports 2018; (2018()) doi:10.1136/bcr-2018-226725.

Diabetes insipidus.

Levy M, Prentice M, Wass J

BMJ (Clinical research ed.) 2019; (364()):l321 doi:10.1136/bmj.l321.

CENTRAL DIABETES INSIPIDUS AND CHEMOTHERAPY: USE OF A CONTINUOUS ARGININE VASOPRESSIN INFUSION FOR FLUID AND SODIUM BALANCE.

Levine JA, Karam SL, O'Connor C, et al.

AACE clinical case reports 2018; (4(6)):e487-e492 doi:10.4158/ACCR-2018-0165.

[Exercise-Associated Hyponatremia in Endurance Performance].

Knechtle B, Chlíbková D, Nikolaidis PT

Praxis 2019; (108(9)):615-632 doi:10.1024/1661-8157/a003261.

[Nephrogenic syndrome of inappropriate antidiuresis].

Nawal B, Izzedine H, Haddiya I, Bentata Y

The Pan African medical journal 2019; (32()):210 doi:10.11604/pamj.2019.32.210.6006.

Copeptin in the differential diagnosis of hypotonic polyuria.

Christ-Crain M, Fenske WK

Journal of endocrinological investigation 2020; (43(1)):21-30 doi:10.1007/s40618-019-01087-6.

Sodium Perturbations After Pituitary Surgery.

Yuen KCJ, Ajmal A, Correa R, Little AS

Neurosurgery clinics of North America 2019; (30(4)):515-524 doi:10.1016/j.nec.2019.05.011.

Vasopressin and Copeptin in health and disease.

Christ-Crain M

Reviews in endocrine & metabolic disorders 2019; (20(3)):283-294 doi:10.1007/s11154-019-09509-9.

Survival Following Extreme Hypernatraemia Associated with Severe Dehydration and Undiagnosed Diabetes Mellitus.

Xiao H, Barmanray R, Qian S, et al.

Case reports in endocrinology 2019; (2019()):4174259 doi:10.1155/2019/4174259.

Molecular aspects of aquaporins.

Li S, Li C, Wang W

Vitamins and hormones 2020; (113()):129-181 doi:10.1016/bs.vh.2019.08.019.

Management of central diabetes insipidus.

Garrahy A, Thompson CJ

Best practice & research. Clinical endocrinology & metabolism 2020; (34(5)):101385 doi:10.1016/j.beem.2020.101385.

Copeptin-based diagnosis of diabetes insipidus.

Refardt J, Christ-Crain M

Swiss medical weekly 2020; (150()):w20237.

Pediatric Pharmacology of Desmopressin in Children with Enuresis: A Comprehensive Review.

Gasthuys E, Dossche L, Michelet R, et al.

Paediatric drugs 2020; (22(4)):369-383 doi:10.1007/s40272-020-00401-7.

Neurosarcoidosis Presentation as Adipsic Diabetes Insipidus Secondary to a Pituitary Stalk Lesion and Association with Anti-NMDA Receptor Antibodies.

Solis JG, Olascoaga Lugo A, Rodríguez Florido MA, et al.

Case reports in neurological medicine 2020; (2020()):7956350 doi:10.1155/2020/7956350.

Use of Desmopressin in Hyponatremia: Foe and Friend.

Achinger SG, Ayus JC

Kidney medicine 2019; (1(2)):65-70 doi:10.1016/j.xkme.2019.02.002.

Acquired forms of central diabetes insipidus: Mechanisms of disease.

Verbalis JG

Best practice & research. Clinical endocrinology & metabolism 2020; (34(5)):101449 doi:10.1016/j.beem.2020.101449.

Diabetes Insipidus: A Pragmatic Approach to Management.

Priya G, Kalra S, Dasgupta A, Grewal E

Cureus 2021; (13(1)):e12498 doi:10.7759/cureus.12498.

Adipsic diabetes insipidus.

Kothari V, Cardona Z, Eisenberg Y

Handbook of clinical neurology 2021; (181()):261-273 doi:10.1016/B978-0-12-820683-6.00019-1.

The combined effect of hypomagnesemia and hypokalemia inducing nephrogenic diabetes insipidus in a patient with type 1 diabetes mellitus.

Sangey E, Chudasama K, Mwinyi A

Clinical case reports 2021; (9(7)):e04564 doi:10.1002/ccr3.4564.

Copeptin as a novel biomarker of cardiometabolic syndrome.

Szmygin H, Szydełko J, Matyjaszek-Matuszek B

Endokrynologia Polska 2021; (72(5)):566-571 doi:10.5603/EP.a2021.0072.

Variability in Oral Desmopressin Dose Requirements in Children with Central Diabetes Insipidus.

Almutlaq N, Eugster EA

The Journal of pediatrics 2021; (239()):228-230 doi:10.1016/j.jpeds.2021.08.087.

Copeptin assays in children for the differential diagnosis of polyuria-polydipsia syndrome and reference levels in hospitalized children.

Bonnet L, Marquant E, Fromonot J, et al.

Clinical endocrinology 2022; (96(1)):47-53 doi:10.1111/cen.14620.

Adipsic diabetes insipidus patient in postoperative pituitary macroadenoma.

García-Ruiz VR, Suárez-Rojas J, Álvarez-Gamero JC, Paz-Ibarra JL

Revista medica del Instituto Mexicano del Seguro Social 2020; (58(6)):740-745 doi:10.24875/RMIMSS.M20000108.

Change in cephalocaudal tumor cavity diameter after transsphenoidal surgery is a predictor of diabetes insipidus in pituitary adenoma.

Lin K, Fan K, Mu S, Wang S

European journal of medical research 2022; (27(1)):72 doi:10.1186/s40001-022-00700-4.

Central diabetes insipidus from a patient's perspective: management, psychological co-morbidities, and renaming of the condition: results from an international web-based survey.

Atila C, Loughrey PB, Garrahy A, et al.

The lancet. Diabetes & endocrinology 2022; (10(10)):700-709 doi:10.1016/S2213-8587(22)00219-4.

Changing the name of diabetes insipidus: a position statement of the working group to consider renaming diabetes insipidus.

Arima H, Cheetham T, Christ-Crain M, et al.

Clinical endocrinology 2024; (101(5)):443-445 doi:10.1111/cen.14819.

Secondary autoimmune hypothalamitis with severe memory impairment 7 years after the onset of diabetes insipidus due to lymphocytic hypophysitis: a case report.

Asada T, Takenoshita S, Senda M, et al.

BMC neurology 2022; (22(1)):371 doi:10.1186/s12883-022-02891-z.

Changing the name of diabetes insipidus: a position statement of The Working Group for Renaming Diabetes Insipidus.

, Arima H, Cheetham T, et al.

European journal of endocrinology 2022; (187(5)):P1-P3 doi:10.1530/EJE-22-0751.

Changing the name of diabetes insipidus: a position statement of The Working Group for Renaming Diabetes Insipidus.

, Arima H, Cheetham T, et al.

Endocrine journal 2022; (69(11)):1281-1284 doi:10.1507/endocrj.EJ20220831.

Changing the name of diabetes insipidus.

Arima H, Bichet DG, Cheetham T, et al.

Pituitary 2022; (25(6)):777-779 doi:10.1007/s11102-022-01276-2.

Changing the Name of Diabetes Insipidus: A Position Statement of the Working Group for Renaming Diabetes Insipidus.

Arima H, Cheetham T, Christ-Crain M, et al.

The Journal of clinical endocrinology and metabolism 2022; (108(1)):1-3 doi:10.1210/clinem/dgac547.

Arginine-stimulated copeptin in children and adolescents.

Binder G, Weber K, Peter A, Schweizer R

Clinical endocrinology 2023; (98(4)):548-553 doi:10.1111/cen.14880.

A case of cerebral salt wasting syndrome in a patient with central diabetes insipidus and status epilepticus.

Bernardi S, Zorat F, Calabrò V, et al.

Journal of endocrinological investigation 2023; (46(6)):1275-1277 doi:10.1007/s40618-023-02053-z.

Endocrine side effects of immune checkpoint inhibitors.

Cardona Z, Sosman JA, Chandra S, Huang W

Frontiers in endocrinology 2023; (14()):1157805 doi:10.3389/fendo.2023.1157805.

Extreme Hypernatremia due to Dehydration.

Kamatam S, Waqar A, Chatterjee T

Journal of medical cases 2023; (14(7)):232-236 doi:10.14740/jmc4124.

Copeptin analysis in endocrine disorders.

Moodley N

Frontiers in endocrinology 2023; (14()):1230045 doi:10.3389/fendo.2023.1230045.

Arginine or Hypertonic Saline-Stimulated Copeptin to Diagnose AVP Deficiency.

Refardt J, Atila C, Chifu I, et al.

The New England journal of medicine 2023; (389(20)):1877-1887 doi:10.1056/NEJMoa2306263.

Glucocorticoid impact therapy for recurrent IgG4-related disease with diabetes insipidus as the main manifestation: A case report and literature review.

Yu Y, Xu L, Wang Y, et al.

Medicine 2023; (102(46)):e36129 doi:10.1097/MD.0000000000036129.

Clinical Factors Affecting Daily Dosage of Desmopressin Orally Disintegrating Tablets in Arginine Vasopressin Deficiency.

Hoshino Y, Inoue K, Ikeda S, et al.

The Journal of clinical endocrinology and metabolism 2024; (109(3)):e983-e996 doi:10.1210/clinem/dgad694.

New insights on diagnosis and treatment of AVP deficiency.

Refardt J, Atila C, Christ-Crain M

Reviews in endocrine & metabolic disorders 2024; (25(3)):639-649 doi:10.1007/s11154-023-09862-w.

Importance of Intraoperative Factors in Postoperative Arginine Vasopressin Deficiency After Pituitary Adenoma Surgery.

Alidaei N, Sharifi G, Davoudi Z

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2024; (30(3)):253-258 doi:10.1016/j.eprac.2023.12.003.

Coexistence of type 2 diabetes mellitus, arginine vasopressin deficiency, and Marfan syndrome: A case report.

Le Y, Zhang J, Hong T, Yang J

Journal of diabetes investigation 2024; (15(7)):964-967 doi:10.1111/jdi.14169.

Psychopathological characteristics in patients with arginine vasopressin deficiency (central diabetes insipidus) and primary polydipsia compared to healthy controls.

Atila C, Beck J, Refardt J, et al.

European journal of endocrinology 2024; (190(5)):354-362 doi:10.1093/ejendo/lvae040.

Arginine vasopressin deficiency: diagnosis, management and the relevance of oxytocin deficiency.

Atila C, Refardt J, Christ-Crain M

Nature reviews. Endocrinology 2024; (20(8)):487-500 doi:10.1038/s41574-024-00985-x.

When Thirst Ceases to Exist: A Case Report and Literature Review of Adipsic Diabetes Insipidus Following Coil Embolization of a Ruptured Anterior Communicating Artery Aneurysm.

Barnett MJ, Patel G, Lekprasert P, et al.

Cureus 2024; (16(7)):e64207 doi:10.7759/cureus.64207.

Exercise-associated Hyponatremia Developing Immediately after a Musical Stage Performance in a Healthy Actress.

Kubo M, Horie I, Tokumitsu JI, et al.

Internal medicine (Tokyo, Japan) 2025; (64(5)):735-740 doi:10.2169/internalmedicine.4112-24.

GLP-1 receptor agonists may enhance the effects of desmopressin in individuals with AVP deficiency: a case series and proposed mechanism.

Nakhleh A, Shehadeh N, Mansour B

Pituitary 2024; (27(5)):731-736 doi:10.1007/s11102-024-01451-7.

Diagnostic Utility of Copeptin in Pediatric Patients with Polyuria-Polydipsia Syndrome: A Systematic Review and Meta-Analysis.

Ciortea DA, Petrea Cliveți CL, Bujoreanu Bezman L, et al.

International journal of molecular sciences 2024; (25(19)) doi:10.3390/ijms251910743.

Delayed onset arginine vasopressin deficiency after traumatic brain injury.

Tomulescu SA, Boto J, Gariani K

Endocrinology, diabetes & metabolism case reports 2024; (2024(4)).

A 4-year-old Boy Positive for Anti-rabphilin-3A Antibody and Diagnosed With Lymphocytic Infundibuloneurohypophysitis.

Yamamoto A, Komatsu N, Iwata N, et al.

JCEM case reports 2025; (3(1)):luae214 doi:10.1210/jcemcr/luae214.

Idiopathic Arginine Vasopressin Deficiency With Mild and Reversible Hypercalcemia.

Malik A, Goyal A, Gupta R, Bhagat A

Ochsner journal 2025; (25(1)):67-72 doi:10.31486/toj.24.0089.

Lymphocytic Hypophysitis Presenting as Acute-onset Arginine Vasopressin Deficiency and Pituitary Stalk Thickening: A Case Report.

Yang LZ, Velaiutham S

Journal of the ASEAN Federation of Endocrine Societies 2025; (40(1)):121-125 doi:10.15605/jafes.040.01.08.

Management of Arginine Vasopressin Deficiency (Central Diabetes Insipidus) in Neonates and Infants.

Pearlstein H, Dayno A, Zook J, et al.

Hormone research in paediatrics 2025; 1-11 doi:10.1159/000547155.

'Un-thirsty' hypernatremia.

Koster M, Ledergerber K, Brändle M

Endocrinology, diabetes & metabolism case reports 2025; (2025(3)).

Idiopathic Arginine Vasopressin Deficiency With an Incidental Non-functional Pituitary Microadenoma in an Elderly Diabetic Woman.

Krishna MSV, Babu DVSP, Singh M, Madhavan S

Cureus 2025; (17(8)):e89995 doi:10.7759/cureus.89995.

A Predictive Score Incorporating Clinical, Radiologic, and Hormonal Parameters to Discriminate Lymphocytic Hypophysitis from Non-Functioning Pituitary Macroadenomas.

Taieb A, Bouzaouache I, Gasmi A, et al.

Diagnostics (Basel, Switzerland) 2025; (15(18)) doi:10.3390/diagnostics15182334.

Route-specific effects of desmopressin on bleeding and hyponatremia after kidney biopsy: meta-analysis of intranasal vs. intravenous administration.

Zheng L, Cai Z, Shao L, et al.

Frontiers in nephrology 2025; (5()):1645418 doi:10.3389/fneph.2025.1645418.

Diagnosis and treatment of hypernatremia.

Tomkins M, Mc Donald D, Green D, et al.

Best practice & research. Clinical endocrinology & metabolism 2026; (40(1)):102065 doi:10.1016/j.beem.2025.102065.

Progression From Isolated Posterior Pituitary Dysfunction to Combined Anterior Hormone Deficiencies With Pituitary Stalk Enlargement in Suspected Lymphocytic Hypophysitis: A Case Report.

Sasaki H, Yagi K, Kuga Y, Katahira H

Cureus 2025; (17(12)):e98595 doi:10.7759/cureus.98595.

Bone turnover in arginine vasopressin deficiency: a comparative study with primary polydipsia and healthy controls.

Varaldo E, Lustenberger S, Atila C, et al.

The Journal of clinical endocrinology and metabolism 2026; (111(6)):e1523-e1531 doi:10.1210/clinem/dgag001.

Medication-Induced Severe Hyponatremia After Elective Surgery in a Patient With Known Arginine Vasopressin Deficiency.

Caputo C, Tomar N, Beitner S

JCEM case reports 2026; (4(2)):luaf319 doi:10.1210/jcemcr/luaf319.

The Diagnostic Challenge of Hypophysitis vs. Non-Functioning Pituitary Macroadenomas: An Updated Review and Comparative Analysis of Distinguishing Criteria.

Ach T, Bouzaouech I, Gasmi A, et al.

Diagnostics (Basel, Switzerland) 2026; (16(2)) doi:10.3390/diagnostics16020328.

Fracture risks in patients with arginine vasopressin deficiency: a nationwide matched cohort study.

Park SS, Jeong H, Ahn CH, et al.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2026; (37(3)):759-770 doi:10.1007/s00198-026-07849-2.

Central Diabetes Insipidus as a Rare Cause of Polyuria.

Bhandari S, Venkatesh SS, Chirag LU, Gowda R

Annals of African medicine 2026; doi:10.4103/aam.aam_583_25.