Research & Literature

Management of gallbladder dyskinesia: patient outcomes following positive ⁹⁹mtechnetium (Tc)-labelled hepatic iminodiacetic acid (HIDA) scintigraphy with cholecystokinin (CCK) provocation and laparoscopic cholecystectomy.

Dave RV, Pathak S, Cockbain AJ, et al.

Clinical radiology 2015; (70(4)):400-7.

Sphincter of Oddi dysfunction Type III: New studies suggest new approaches are needed.

Wilcox CM

World journal of gastroenterology 2015; (21(19)):5755-61 doi:10.3748/wjg.v21.i19.5755.

Incidence and predictors of post-ERCP pancreatitis in patients with suspected sphincter of Oddi dysfunction undergoing biliary or dual sphincterotomy: results from the EPISOD prospective multicenter randomized sham-controlled study.

Yaghoobi M, Pauls Q, Durkalski V, et al.

Endoscopy 2015; (47(10)):884-90 doi:10.1055/s-0034-1392418.

Initial Misdiagnosis of Proximal Pancreatic Adenocarcinoma Is Associated with Delay in Diagnosis and Advanced Stage at Presentation.

Swords DS, Mone MC, Zhang C, et al.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2015; (19(10)):1813-21 doi:10.1007/s11605-015-2923-z.

Pilot Randomized Controlled Trial of Laparoscopic Cholecystectomy vs Active Nonoperative Therapy for the Treatment of Biliary Dyskinesia.

Richmond BK, Grodman C, Walker J, et al.

Journal of the American College of Surgeons 2016; (222(6)):1156-63.

Rome IV. Gallbladder and Sphincter of Oddi Disorders.

Cotton PB, Elta GH, Carter CR, et al.

Gastroenterology 2016; doi:10.1053/j.gastro.2016.02.033.

Biliary Dyskinesia in Children: A Systematic Review.

Santucci NR, Hyman PE, Harmon CM, et al.

Journal of pediatric gastroenterology and nutrition 2017; (64(2)):186-193 doi:10.1097/MPG.0000000000001357.

Post-cholecystectomy syndrome and sphincter of Oddi dysfunction: past, present and future.

Tarnasky PR

Expert review of gastroenterology & hepatology 2016; (10(12)):1359-1372 doi:10.1080/17474124.2016.1251308.

HIDA scan for functional gallbladder disorder: ensure that you know how the scan was done.

Goussous N, Maqsood H, Spiegler E, et al.

Hepatobiliary & pancreatic diseases international : HBPD INT 2017; (16(2)):197-201 doi:10.1016/s1499-3872(16)60188-1.

The EPISOD study: long-term outcomes.

Cotton PB, Pauls Q, Keith J, et al.

Gastrointestinal endoscopy 2018; (87(1)):205-210 doi:10.1016/j.gie.2017.04.015.

Decision-making patterns in managing children with suspected biliary dyskinesia.

Nakayuenyongsuk W, Choudry H, Yeung KA, Karnsakul W

World journal of clinical pediatrics 2017; (6(2)):124-131 doi:10.5409/wjcp.v6.i2.124.

Poor Reproducibility of Gallbladder Ejection Fraction by Biliary Scintigraphy for Diagnosis of Biliary Dyskinesia.

Rose JB, Fields RC, Strasberg SM

Journal of the American College of Surgeons 2018; (226(2)):155-159 doi:10.1016/j.jamcollsurg.2017.10.025.

Systematic review with meta-analysis: cholecystectomy for biliary dyskinesia-what can the gallbladder ejection fraction tell us?

Gudsoorkar VS, Oglat A, Jain A, et al.

Alimentary pharmacology & therapeutics 2019; (49(6)):654-663 doi:10.1111/apt.15128.

Sincalide: A Review of Clinical Utility, Proper Infusion Methodology, and Alternative Cholecystogogues.

Ziessman HA

Journal of nuclear medicine technology 2019; (47(3)):210-212 doi:10.2967/jnmt.119.226019.

Etiologies of Long-Term Postcholecystectomy Symptoms: A Systematic Review.

Latenstein CSS, Wennmacker SZ, de Jong JJ, et al.

Gastroenterology research and practice 2019; (2019()):4278373 doi:10.1155/2019/4278373.

Role of laparoscopic cholecystectomy in the management of chronic right upper quadrant pain due to biliary dyskinesia: a systematic review and meta-analysis.

Rehman S, Singh KK, Sajid MS

Translational gastroenterology and hepatology 2019; (4()):71 doi:10.21037/tgh.2019.08.10.

Readmission to hospital following laparoscopic cholecystectomy: a meta-analysis.

McIntyre C, Johnston A, Foley D, et al.

Anaesthesiology intensive therapy 2020; (52(1)):47-55 doi:10.5114/ait.2020.92967.

HIDA and Seek: Challenges of Scintigraphy to Diagnose Bile Reflux Post-Bariatric Surgery.

Eldredge TA, Bills M, Myers JC, et al.

Obesity surgery 2020; (30(5)):2038-2045 doi:10.1007/s11695-020-04510-7.

Cholescintigraphy may have a role in selecting patients with biliary dyskinesia for cholecystectomy: a systematic review.

Alhayo S, Eslick GD, Cox MR

ANZ journal of surgery 2020; (90(9)):1647-1652 doi:10.1111/ans.16003.

Functional Dyspepsia and Irritable Bowel Syndrome are Highly Prevalent in Patients With Gallstones and Are Negatively Associated With Outcomes After Cholecystectomy: A Prospective, Multicenter, Observational Study (PERFECT - Trial).

de Jong JJ, Latenstein CSS, Boerma D, et al.

Annals of surgery 2022; (275(6)):e766-e772 doi:10.1097/SLA.0000000000004453.

Optimal Management of the Hyperkinetic Gallbladder: A Comparison of Outcomes Between Operative and Nonoperative Approaches.

Williford ML, Fay KT, Simpson FJ, et al.

The American surgeon 2021; (87(6)):903-909 doi:10.1177/0003134820966283.

Biliary Dyskinesia: Current Perspectives and Future Directions.

Richmond BK, Walker A

The American surgeon 2021; (87(6)):954-960 doi:10.1177/0003134820971617.

Laparoscopic Cholecystectomy for Gallbladder Dysfunction and Polyps: Incidence and Follow up.

Qandeel H, Nassar AHM, Ng HJ, El Zanati H

JSLS : Journal of the Society of Laparoendoscopic Surgeons 2021; (25(2)) doi:10.4293/JSLS.2021.00009.

Rates of Bile Acid Diarrhoea After Cholecystectomy: A Multicentre Audit.

Farrugia A, Attard JA, Hanmer S, et al.

World journal of surgery 2021; (45(8)):2447-2453 doi:10.1007/s00268-021-06147-8.

AGA Clinical Practice Update on Management of Chronic Gastrointestinal Pain in Disorders of Gut-Brain Interaction: Expert Review.

Keefer L, Ko CW, Ford AC

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2021; (19(12)):2481-2488.e1 doi:10.1016/j.cgh.2021.07.006.

Mast cell infiltration and activation in the gallbladder wall: Implications for the pathogenesis of functional gallbladder disorder in adult patients.

Arshi J, Layfield LJ, Esebua M

Annals of diagnostic pathology 2021; (54()):151798 doi:10.1016/j.anndiagpath.2021.151798.

Clinical utility of stimulated cholescintigraphy using a standardized Ensure-Plus fatty meal protocol in patients with suspected functional gallbladder disorder: a retrospective study of seven-years clinical experience.

Li AY, Yue H, Kavnoudias H, et al.

ANZ journal of surgery 2022; (92(4)):774-780 doi:10.1111/ans.17388.

Sincalide-Stimulated Cholescintigraphy: A Retrospective Study and Proposal of a Modified Workflow.

Vasireddi A, Nguyen NC

Clinical nuclear medicine 2022; (47(1)):1-6 doi:10.1097/RLU.0000000000003959.

Review article: Diagnosis and investigation of irritable bowel syndrome.

Black CJ

Alimentary pharmacology & therapeutics 2021; (54 Suppl 1()):S33-S43 doi:10.1111/apt.16597.

Efficacy of Chenodeoxycholic Acid and Ursodeoxycholic Acid Treatments for Refractory Functional Dyspepsia.

Jang SI, Lee TH, Jeong S, et al.

Journal of clinical medicine 2022; (11(11)) doi:10.3390/jcm11113190.

Gallbladder Dyskinesia.

Presti ME, Elwing JE, Sayuk GS

Southern medical journal 2022; (115(11)):838-841 doi:10.14423/SMJ.0000000000001466.

Elevated Levels of PGE2-Metabolite in Cerebrospinal Fluid and Cox-2 Gene Polymorphisms in Patients with Chronic, Post Cholecystectomy Pain and Visceral Hyperalgesia Compared to Healthy Controls. A Hypothesis-Generating Pilot Study.

Blichfeldt-Eckhardt MR, Olsen DA, Andersen RF, et al.

Journal of pain research 2022; (15()):3921-3929 doi:10.2147/JPR.S387502.

Embolization of an incomplete isolated right segmental hepatic duct injury (incomplete IRSHDI)-A case report.

Rott G, Boecker F

Radiology case reports 2023; (18(3)):1156-1160 doi:10.1016/j.radcr.2022.12.005.

Approach to Disorders of Gut-Brain Interaction.

Tome J, Kamboj AK, Loftus CG

Mayo Clinic proceedings 2023; (98(3)):458-467 doi:10.1016/j.mayocp.2022.11.001.

Do not get stumped: multimodality imaging findings of early and late post-cholecystectomy complications.

Maddu K, Polireddy K, Hsu D, Hoff C

Emergency radiology 2023; (30(3)):351-362 doi:10.1007/s10140-023-02131-y.

Initial management of suspected biliary injury after laparoscopic cholecystectomy.

Siiki A, Ahola R, Vaalavuo Y, et al.

World journal of gastrointestinal surgery 2023; (15(4)):592-599 doi:10.4240/wjgs.v15.i4.592.

Defining Biliary Hyperkinesia and the Role of Cholecystectomy.

Kartik A, Jorge IA, Webb C, et al.

Journal of the American College of Surgeons 2023; (237(5)):706-710 doi:10.1097/XCS.0000000000000793.

Development of functional gastrointestinal disorder symptoms following laparoscopic cholecystectomy: a prospective cohort study.

Chang JY, Jung HK, Moon CM, et al.

Frontiers in medicine 2023; (10()):1248465 doi:10.3389/fmed.2023.1248465.

Functional gallbladder disorder: Interim analysis of a prospective cohort study.

Xu KJ, Brock JC, Goussous N, et al.

American journal of surgery 2024; (229()):129-132 doi:10.1016/j.amjsurg.2023.12.010.

The impact of cholecystectomy on the symptom relief and quality of life of patients with gallbladder dysmotility.

Alamin N, Iqbal S, Baumert A, Fernandes R

World journal of surgery 2024; (48(7)):1651-1655 doi:10.1002/wjs.12171.

Biliary Dyskinesia-Controversies, Diagnosis, and Management: A Review.

Richmond BK

JAMA surgery 2024; (159(9)):1079-1084 doi:10.1001/jamasurg.2024.0818.

Evaluation of Diet and Symptom Severity in Disorder of Gut-Brain Interaction.

Faruga-Lewicka W, Bielaszka A, Staśkiewicz-Bartecka W, et al.

Journal of clinical medicine 2024; (13(14)) doi:10.3390/jcm13144132.

Hyperkinetic Biliary Dyskinesia: An Underrecognized Problem With Good Surgical Outcomes After Cholecystectomy.

Camacho KD, Cohen RB, Kapadia S, et al.

Cureus 2024; (16(6)):e63237 doi:10.7759/cureus.63237.

The Management of Dysfunctional Gallbladder Disease and the Role of Laparoscopic Cholecystectomy on Symptom Improvement: A Retrospective Cohort Study.

Abuahmed MY, Wuheb A, Eskandar G, et al.

Cureus 2024; (16(7)):e64726 doi:10.7759/cureus.64726.

Symptom bothersomeness and life interference support Rome clinical criteria as clinically relevant indicators of DGBI.

Coitinho Biurra Y, Naude C, Marchese SH, et al.

Neurogastroenterology and motility 2024; (36(12)):e14936 doi:10.1111/nmo.14936.

Four-Year Report of Iatrogenic Bile Duct Injury Repair from a Referral Hepatobiliary Center.

Zarghami SY, Ghafoury R, Fakhar N, et al.

Middle East journal of digestive diseases 2024; (16(3)):173-177 doi:10.34172/mejdd.2024.385.

Biliary Dyskinesia and Hyperkinesis.

Tseng J, Chen Y, McDonald C

The Surgical clinics of North America 2024; (104(6)):1191-1201 doi:10.1016/j.suc.2024.04.007.

Biliary Dyskinesia with Reduced Gallbladder Ejection Fraction: A Diagnostic and Therapeutic Shift in Management.

Elaskandrany MA, Ismail M, Liu Y, Wang WW

Journal of Brown hospital medicine 2025; (4(1)):6-9 doi:10.56305/001c.127836.

Post-cholecystectomy bile acid diarrhea in a teenager with sickle cell disease: Case report.

Sumbizi CE, Hassan O, Mbuma R, et al.

International journal of surgery case reports 2025; (136()):112018 doi:10.1016/j.ijscr.2025.112018.

Functional Gallbladder Disorders: Are We Missing Gallstones?

Kendric TJG, Apikotoa SA, Ng ZQ, Wijesuriya R

World journal of surgery 2026; (50(2)):353-359 doi:10.1002/wjs.70230.

Gallbladder and Sphincter of Oddi Disorders.

Elmunzer BJ, Winslow E, De Giorgio R, et al.

Gastroenterology 2026; (170(6)):1303-1317 doi:10.1053/j.gastro.2026.01.035.

Refractory Hyperkinetic Biliary Colic: A Case of Biliary Dyskinesia.

Coe B, Elkhashab I, Haroon MA, Frasso CN

Cureus 2026; (18(1)):e102226 doi:10.7759/cureus.102226.

Reconceptualizing negative endoscopy as a positive contextual indicator for disorders of gut-brain interaction.

Zhang W, Zeng H, Ruan QN, Zeng D

Frontiers in physiology 2026; (17()):1795494 doi:10.3389/fphys.2026.1795494.

Severe Gallbladder Dyskinesia With 2% Ejection Fraction: A Comprehensive Clinicoradiologic and Pathologic Case Correlation.

Rahming N, De Almeida S, Armbrister U, et al.

Cureus 2026; (18(2)):e104416 doi:10.7759/cureus.104416.

The Chronic Acalculous Symptomatic Hyperkinetic (CASPER) Gallbladder or "The Excitable Gallbladder".

Samuel I

JSM gastroenterology and hepatology 2023; (10(1)).