Research & Literature

Evidence-Based Pharmacologic Therapies for Prevention of Bronchopulmonary Dysplasia: Application of the Grading of Recommendations Assessment, Development, and Evaluation Methodology.

Jensen EA, Foglia EE, Schmidt B

Clinics in perinatology 2015; (42(4)):755-79.

Pulmonary Hypertension and Vascular Abnormalities in Bronchopulmonary Dysplasia.

Mourani PM, Abman SH

Clinics in perinatology 2015; (42(4)):839-55.

Pulmonary hypertension specific treatment in infants with bronchopulmonary dysplasia.

Kadmon G, Schiller O, Dagan T, et al.

Pediatric pulmonology 2017; (52(1)):77-83 doi:10.1002/ppul.23508.

Optimal mechanical ventilation strategies to minimize ventilator-induced lung injury in non-injured and injured lungs.

Silva PL, Pelosi P, Rocco PR

Expert review of respiratory medicine 2016; (10(12)):1243-1245 doi:10.1080/17476348.2016.1251842.

Scoping review shows wide variation in the definitions of bronchopulmonary dysplasia in preterm infants and calls for a consensus.

Hines D, Modi N, Lee SK, et al.

Acta paediatrica (Oslo, Norway : 1992) 2017; (106(3)):366-374 doi:10.1111/apa.13672.

Interdisciplinary Care of Children with Severe Bronchopulmonary Dysplasia.

Abman SH, Collaco JM, Shepherd EG, et al.

The Journal of pediatrics 2017; (181()):12-28.e1 doi:10.1016/j.jpeds.2016.10.082.

Lung function development after preterm birth in relation to severity of Bronchopulmonary dysplasia.

Um-Bergström P, Hallberg J, Thunqvist P, et al.

BMC pulmonary medicine 2017; (17(1)):97 doi:10.1186/s12890-017-0441-3.

Postnatal corticosteroids to prevent or treat bronchopulmonary dysplasia - Who might benefit?

Doyle LW, Cheong JLY

Seminars in fetal & neonatal medicine 2017; (22(5)):290-295 doi:10.1016/j.siny.2017.07.003.

Past, Present and Future Approaches to the Prevention and Treatment of Respiratory Syncytial Virus Infection in Children.

Simões EAF, Bont L, Manzoni P, et al.

Infectious diseases and therapy 2018; (7(1)):87-120 doi:10.1007/s40121-018-0188-z.

Molecular Mechanisms of Ventilator-Induced Lung Injury.

Chen L, Xia HF, Shang Y, Yao SL

Chinese medical journal 2018; (131(10)):1225-1231 doi:10.4103/0366-6999.226840.

Polysomnography for the management of oxygen supplementation therapy in infants with chronic lung disease of prematurity.

Kulkarni G, de Waal K, Grahame S, et al.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2019; (32(21)):3640-3646 doi:10.1080/14767058.2018.1470234.

The Impact of Bronchopulmonary Dysplasia on Childhood Outcomes.

DeMauro SB

Clinics in perinatology 2018; (45(3)):439-452 doi:10.1016/j.clp.2018.05.006.

The Impact of Pulmonary Hypertension in Preterm Infants with Severe Bronchopulmonary Dysplasia through 1 Year.

Lagatta JM, Hysinger EB, Zaniletti I, et al.

The Journal of pediatrics 2018; (203()):218-224.e3 doi:10.1016/j.jpeds.2018.07.035.

Comparison of Early Nasal Intermittent Positive Pressure Ventilation and Nasal Continuous Positive Airway Pressure in Preterm Infants with Respiratory Distress Syndrome.

Dursun M, Uslu S, Bulbul A, et al.

Journal of tropical pediatrics 2019; (65(4)):352-360 doi:10.1093/tropej/fmy058.

An update on pulmonary and neurodevelopmental outcomes of bronchopulmonary dysplasia.

Cheong JLY, Doyle LW

Seminars in perinatology 2018; (42(7)):478-484 doi:10.1053/j.semperi.2018.09.013.

[Clinical features and prognosis of bronchopulmonary dysplasia complicated by pulmonary hypertension in preterm infants].

Wang CH, Shi LP, Ma XL, DU LZ

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 2018; (20(11)):893-896.

Eliminating Risk of Intubation in Very Preterm Infants with Noninvasive Cardiorespiratory Support in the Delivery Room and Neonatal Intensive Care Unit.

Govindaswami B, Nudelman M, Narasimhan SR, et al.

BioMed research international 2019; (2019()):5984305 doi:10.1155/2019/5984305.

Impact of a protocol-driven unified service for neonates with bronchopulmonary dysplasia.

Batey N, Batra D, Dorling J, Bhatt JM

ERJ open research 2019; (5(1)) doi:10.1183/23120541.00183-2018.

Loss of interleukin-6 enhances the inflammatory response associated with hyperoxia-induced lung injury in neonatal mice.

Li H, Wang G, Lin S, et al.

Experimental and therapeutic medicine 2019; (17(4)):3101-3107 doi:10.3892/etm.2019.7315.

Bronchopulmonary Dysplasia and Pulmonary Outcomes of Prematurity.

Tracy MK, Berkelhamer SK

Pediatric annals 2019; (48(4)):e148-e153 doi:10.3928/19382359-20190325-03.

The Diagnosis of Bronchopulmonary Dysplasia in Very Preterm Infants. An Evidence-based Approach.

Jensen EA, Dysart K, Gantz MG, et al.

American journal of respiratory and critical care medicine 2019; (200(6)):751-759 doi:10.1164/rccm.201812-2348OC.

Bronchopulmonary Dysplasia: When the Very Preterm Baby Comes Home.

Anderson C, Hillman NH

Missouri medicine 2019; (116(2)):117-122.

Interleukin-1 Receptor Antagonist Protects Newborn Mice Against Pulmonary Hypertension.

Bui CB, Kolodziej M, Lamanna E, et al.

Frontiers in immunology 2019; (10()):1480 doi:10.3389/fimmu.2019.01480.

Using continuous overnight pulse oximetry to guide home oxygen therapy in chronic neonatal lung disease.

Wong MD, Chung H, Chawla J

Journal of paediatrics and child health 2020; (56(2)):309-316 doi:10.1111/jpc.14606.

High Flow Nasal Cannula versus Nasal Continuous Positive Airway Pressure for Primary Respiratory Support in Preterm Infants: A Prospective Randomized Study.

Demirel G, Vatansever B, Tastekin A

American journal of perinatology 2021; (38(3)):237-241 doi:10.1055/s-0039-1696673.

Factors associated with development of early and late pulmonary hypertension in preterm infants with bronchopulmonary dysplasia.

Sheth S, Goto L, Bhandari V, et al.

Journal of perinatology : official journal of the California Perinatal Association 2020; (40(1)):138-148 doi:10.1038/s41372-019-0549-9.

Bronchopulmonary dysplasia.

Thébaud B, Goss KN, Laughon M, et al.

Nature reviews. Disease primers 2019; (5(1)):78 doi:10.1038/s41572-019-0127-7.

Lung Function of Adults Born at Very Low Birth Weight.

Yang J, Kingsford RA, Horwood J, et al.

Pediatrics 2020; (145(2)) doi:10.1542/peds.2019-2359.

Bronchopulmonary dysplasia: A review of the pulmonary sequelae in the post-surfactant era.

Haggie S, Robinson P, Selvadurai H, Fitzgerald DA

Journal of paediatrics and child health 2020; (56(5)):680-689 doi:10.1111/jpc.14878.

Invasive mechanical ventilation and biomarkers as predictors of bronchopulmonary dysplasia in preterm infants.

Nascimento CP, Maia LP, Alves PT, et al.

Jornal de pediatria 2021; (97(3)):280-286 doi:10.1016/j.jped.2020.03.006.

Signaling Pathways Involved in the Development of Bronchopulmonary Dysplasia and Pulmonary Hypertension.

Mathew R

Children (Basel, Switzerland) 2020; (7(8)) doi:10.3390/children7080100.

Using a home oxygen weaning protocol and pCO2 to evaluate outcomes for infants with bronchopulmonary dysplasia discharged on home oxygen.

Dawson SK, D'Andrea LA, Lau R, Lagatta JM

Pediatric pulmonology 2020; (55(12)):3293-3303 doi:10.1002/ppul.25057.

Involvement of Hdac3-mediated inhibition of microRNA cluster 17-92 in bronchopulmonary dysplasia development.

Wang D, Hong H, Li XX, et al.

Molecular medicine (Cambridge, Mass.) 2020; (26(1)):99 doi:10.1186/s10020-020-00237-4.

Newer bronchopulmonary dysplasia definitions and prediction of health economics impacts in very preterm infants.

Kurihara C, Zhang L, Mikhael M

Pediatric pulmonology 2021; (56(2)):409-417 doi:10.1002/ppul.25172.

Weaning oxygen in infants with bronchopulmonary dysplasia.

Everitt LH, Awoseyila A, Bhatt JM, et al.

Paediatric respiratory reviews 2021; (39()):82-89 doi:10.1016/j.prrv.2020.10.005.

Simplified bedside assessment of pulmonary gas exchange in very preterm infants at 36 weeks' postmenstrual age.

Stoecklin B, Choi YJ, Rakshasbhuvankar A, et al.

Thorax 2021; (76(7)):689-695 doi:10.1136/thoraxjnl-2020-214659.

Room air challenge predicts duration of supplemental respiratory support for infants with bronchopulmonary dysplasia.

Arora P, Dahlgren A, Dawson S, et al.

Journal of perinatology : official journal of the California Perinatal Association 2021; (41(4)):772-778 doi:10.1038/s41372-021-00958-2.

Non-Invasive Ventilatory Strategies to Decrease Bronchopulmonary Dysplasia-Where Are We in 2021?

Dumpa V, Bhandari V

Children (Basel, Switzerland) 2021; (8(2)) doi:10.3390/children8020132.

Bronchopulmonary dysplasia as a determinant of respiratory outcomes in adult life.

Collaco JM, McGrath-Morrow SA

Pediatric pulmonology 2021; (56(11)):3464-3471 doi:10.1002/ppul.25301.

Hyperoxia-activated circulating extracellular vesicles induce lung and brain injury in neonatal rats.

Ali A, Zambrano R, Duncan MR, et al.

Scientific reports 2021; (11(1)):8791 doi:10.1038/s41598-021-87706-w.

Evidence for the Management of Bronchopulmonary Dysplasia in Very Preterm Infants.

Muehlbacher T, Bassler D, Bryant MB

Children (Basel, Switzerland) 2021; (8(4)) doi:10.3390/children8040298.

Postnatal Corticosteroids to Prevent or Treat Bronchopulmonary Dysplasia.

Doyle LW

Neonatology 2021; (118(2)):244-251 doi:10.1159/000515950.

Should Vitamin A Injections to Prevent Bronchopulmonary Dysplasia or Death Be Reserved for High-Risk Infants? Reanalysis of the National Institute of Child Health and Human Development Neonatal Research Network Randomized Trial.

Rysavy MA, Li L, Tyson JE, et al.

The Journal of pediatrics 2021; (236()):78-85.e5 doi:10.1016/j.jpeds.2021.05.022.

Corpus Callosum Growth and Neurodevelopmental Outcome Are Negatively Influenced by Systemic Infection in Very Low-Birth-Weight Infants.

Korček P, Korčeková Z, Berka I, et al.

Journal of child neurology 2021; (36(10)):883-887 doi:10.1177/08830738211016239.

Severity of Bronchopulmonary Dysplasia Among Very Preterm Infants in the United States.

Jensen EA, Edwards EM, Greenberg LT, et al.

Pediatrics 2021; (148(1)) doi:10.1542/peds.2020-030007.

Differences in Comorbidities and Clinical Burden of Severe Bronchopulmonary Dysplasia Based on Disease Severity.

Kim HR, Jung YH, Kim BI, et al.

Frontiers in pediatrics 2021; (9()):664033 doi:10.3389/fped.2021.664033.

Risk factors for hospitalisation due to respiratory syncytial virus infection in children receiving prophylactic palivizumab.

Chida-Nagai A, Sato H, Sato I, et al.

European journal of pediatrics 2022; (181(2)):539-547 doi:10.1007/s00431-021-04216-7.

Short- and Long-Term Complications of Bronchopulmonary Dysplasia.

Homan TD, Nayak RP

Respiratory care 2021; (66(10)):1618-1629 doi:10.4187/respcare.08401.

Diagnosis and management of bronchopulmonary dysplasia.

Gilfillan M, Bhandari A, Bhandari V

BMJ (Clinical research ed.) 2021; (375()):n1974 doi:10.1136/bmj.n1974.

Ventilation-Induced Lung Injury (VILI) in Neonates: Evidence-Based Concepts and Lung-Protective Strategies.

Kalikkot Thekkeveedu R, El-Saie A, Prakash V, et al.

Journal of clinical medicine 2022; (11(3)) doi:10.3390/jcm11030557.

The Role of Sphingolipid Signaling in Oxidative Lung Injury and Pathogenesis of Bronchopulmonary Dysplasia.

Thomas JM, Sudhadevi T, Basa P, et al.

International journal of molecular sciences 2022; (23(3)) doi:10.3390/ijms23031254.

Perinatal Hyperoxia and Developmental Consequences on the Lung-Brain Axis.

Obst S, Herz J, Alejandre Alcazar MA, et al.

Oxidative medicine and cellular longevity 2022; (2022()):5784146 doi:10.1155/2022/5784146.

Enteral Feeding/Total Fluid Intake Ratio Is Associated With Risk of Bronchopulmonary Dysplasia in Extremely Preterm Infants.

Lin B, Xiong X, Lu X, et al.

Frontiers in pediatrics 2022; (10()):899785 doi:10.3389/fped.2022.899785.

Effectiveness and safety of early versus late caffeine therapy in managing apnoea of prematurity among preterm infants: a retrospective cohort study.

Yun WZ, Kassab YW, Yao LM, et al.

International journal of clinical pharmacy 2022; (44(5)):1140-1148 doi:10.1007/s11096-022-01437-0.

Intrauterine Ureaplasma is associated with small airway obstruction in extremely preterm infants.

Kitajima H, Fujimura M, Takeuchi M, et al.

Pediatric pulmonology 2022; (57(11)):2763-2773 doi:10.1002/ppul.26098.

Platelets are indispensable for alveolar development in neonatal mice.

Huang Z, Lin B, Han D, et al.

Frontiers in pediatrics 2022; (10()):943054 doi:10.3389/fped.2022.943054.

Comparison of New Bronchopulmonary Dysplasia Definitions on Long-Term Outcomes in Preterm Infants.

Katz TA, van Kaam AH, Schuit E, et al.

The Journal of pediatrics 2023; (253()):86-93.e4 doi:10.1016/j.jpeds.2022.09.022.

Is bronchopulmonary dysplasia in adult age a novel COPD endotype?

Bonadies L, Papi A, Baraldi E

The European respiratory journal 2022; (60(3)) doi:10.1183/13993003.00984-2022.

Role of left atrial hypertension in pulmonary hypertension associated with bronchopulmonary dysplasia.

Sullivan RT, Tandel MD, Bhombal S, et al.

Frontiers in pediatrics 2022; (10()):1012136 doi:10.3389/fped.2022.1012136.

Management of diuretics in infants with bronchopulmonary dysplasia discharged on home oxygen.

Dawson SK, D'Andrea LA, Lagatta JM

Pediatric pulmonology 2023; (58(2)):522-529 doi:10.1002/ppul.26221.

Comparison Between Continuous Positive Airway Pressure and High-Flow Nasal Cannula as Postextubation Respiratory Support in Neonates: A Systematic Review and Meta-Analysis.

Martins C, Pissarra R, Costa S, et al.

Turkish archives of pediatrics 2022; (57(6)):581-590 doi:10.5152/TurkArchPediatr.2022.22161.

The follow up of complex infants in an aerodigestive clinic.

Kaspy KR, Burg G, Garrison AP, et al.

Paediatric respiratory reviews 2022; (44()):3-10 doi:10.1016/j.prrv.2022.06.002.

A review and guide to nutritional care of the infant with established bronchopulmonary dysplasia.

Miller AN, Curtiss J, Taylor SN, et al.

Journal of perinatology : official journal of the California Perinatal Association 2023; (43(3)):402-410 doi:10.1038/s41372-022-01578-0.

Diagnosis and management of pulmonary hypertension in infants with bronchopulmonary dysplasia: a guide for paediatric respiratory specialists.

Chan S, Brugha R, Quyam S, Moledina S

Breathe (Sheffield, England) 2022; (18(4)):220209 doi:10.1183/20734735.0209-2022.

Bronchopulmonary Dysplasia: Pathogenesis and Pathophysiology.

Dankhara N, Holla I, Ramarao S, Kalikkot Thekkeveedu R

Journal of clinical medicine 2023; (12(13)) doi:10.3390/jcm12134207.

Early nasal intermittent positive pressure ventilation (NIPPV) versus early nasal continuous positive airway pressure (NCPAP) for preterm infants.

Lemyre B, Deguise MO, Benson P, et al.

The Cochrane database of systematic reviews 2023; (7()):CD005384 doi:10.1002/14651858.CD005384.pub3.

Development and Disorders of the Airway in Bronchopulmonary Dysplasia.

Bush D, Juliano C, Bowler S, Tiozzo C

Children (Basel, Switzerland) 2023; (10(7)) doi:10.3390/children10071127.

Pathogenesis and Physiologic Mechanisms of Neonatal Pulmonary Hypertension: Preclinical Studies.

Young KC, Schmidt AF, Tan AW, et al.

Clinics in perinatology 2024; (51(1)):21-43 doi:10.1016/j.clp.2023.11.004.

Nutritional support during the first week for infants with bronchopulmonary dysplasia and respiratory distress: a multicenter cohort study in China.

Lin H, Bai G, Ge J, et al.

BMC pediatrics 2024; (24(1)):238 doi:10.1186/s12887-024-04675-5.

Delta like 4 regulates cerebrovascular development and endothelial integrity via DLL4-NOTCH-CLDN5 pathway and is vulnerable to neonatal hyperoxia.

Ke X, Xia S, Yu W, et al.

The Journal of physiology 2024; (602(10)):2265-2285 doi:10.1113/JP285716.

Pulmonary function and bronchopulmonary dysplasia classification: insights from the Spanish Registry.

Ramos-Navarro C, Sánchez-Luna M, Pérez-Tarazona S, et al.

European journal of pediatrics 2024; (183(9)):3757-3766 doi:10.1007/s00431-024-05629-w.

Optimal Strategies of Mechanical Ventilation: Can We Avoid or Reduce Lung Injury?

van Kaam AH

Neonatology 2024; (121(5)):570-575 doi:10.1159/000539346.

Long-term lung function follow-up of preterm infants less than 32 weeks of gestational age.

Merino-Hernández A, Muñoz-Cutillas A, Ramos-Navarro C, et al.

Pediatric pulmonology 2024; (59(11)):2922-2931 doi:10.1002/ppul.27158.

Effect of Low Dose Glucocorticoid Inhalation on Bronchopulmonary Dysplasia in Premature Infants.

Li X, Liu H

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 2025; (57(2)):96-100 doi:10.1055/a-2414-3061.

Pulmonary hypertension in preterm neonates with bronchopulmonary dysplasia: a meta-analysis.

Mascarenhas D, Al-Balushi M, Al-Sabahi A, et al.

Archives of disease in childhood. Fetal and neonatal edition 2025; (110(4)):344-352 doi:10.1136/archdischild-2024-327547.

Research progress of microvascular development in bronchopulmonary dysplasia.

Zhang J, Du W, Zhang Z, et al.

Pediatric investigation 2024; (8(4)):299-312 doi:10.1002/ped4.12441.

Intrauterine inflammation-induced neonatal lung injury via succinic acid-mediated alveolar epithelial E-cadherin downregulation.

Li B, Chen Z, Yao D, et al.

American journal of physiology. Lung cellular and molecular physiology 2025; (329(2)):L282-L295 doi:10.1152/ajplung.00322.2024.

Palivizumab for preventing severe respiratory syncytial virus (RSV) infection in children.

Garegnani L, Roson Rodriguez P, Escobar Liquitay CM, et al.

The Cochrane database of systematic reviews 2025; (7()):CD013757 doi:10.1002/14651858.CD013757.pub3.

Screening for pulmonary hypertension in preterm infants with bronchopulmonary dysplasia: when, how often and does it matter?

Gentle SJ, Carlo WA, Ambalavanan N

Archives of disease in childhood. Fetal and neonatal edition 2026; (111(2)):F177-F182 doi:10.1136/archdischild-2024-328405.

Respiratory Outcomes Following Late Postnatal Dexamethasone Administration in Preterm Infants With Bronchopulmonary Dysplasia.

House M, Rowe J, Walters A, et al.

Pediatric pulmonology 2025; (60(9)):e71275 doi:10.1002/ppul.71275.

Nutrition Strategies for the Preterm Infant with Bronchopulmonary Dysplasia.

Trindade GS, Benincasa BC, Procianoy GS, et al.

Nutrients 2025; (17(21)) doi:10.3390/nu17213472.

Targeted Neonatal Echocardiography in Bronchopulmonary Dysplasia: A Framework for Screening and Management of Chronic Pulmonary Hypertension.

Hébert A, Villeneuve A, Lapointe A, et al.

Journal of clinical medicine 2025; (14(22)) doi:10.3390/jcm14228161.

Lung trajectories into adulthood of preterm born survivors and the influence of sex.

Bui DS, Berry CD, Idrose NS, et al.

Paediatric respiratory reviews 2025; doi:10.1016/j.prrv.2025.12.001.