Research & Literature

Improving response inhibition systems in frontotemporal dementia with citalopram.

Hughes LE, Rittman T, Regenthal R, et al.

Brain : a journal of neurology 2015; (138(Pt 7)):1961-75 doi:10.1093/brain/awv133.

Review: an update on clinical, genetic and pathological aspects of frontotemporal lobar degenerations.

Lashley T, Rohrer JD, Mead S, Revesz T

Neuropathology and applied neurobiology 2015; (41(7)):858-81 doi:10.1111/nan.12250.

[Genetics of dementia].

Diehl-Schmid J, Oexle K

Der Nervenarzt 2015; (86(7)):891-900; quiz 901-2 doi:10.1007/s00115-015-4276-y.

Neuropsychiatric Symptoms, Caregiver Burden and Distress in Behavioral-Variant Frontotemporal Dementia and Alzheimer's Disease.

Lima-Silva TB, Bahia VS, Carvalho VA, et al.

Dementia and geriatric cognitive disorders 2015; (40(5-6)):268-75 doi:10.1159/000437351.

Progression in Behavioral Variant Frontotemporal Dementia: A Longitudinal Study.

Devenney E, Bartley L, Hoon C, et al.

JAMA neurology 2015; (72(12)):1501-9 doi:10.1001/jamaneurol.2015.2061.

Frontotemporal dementia.

Bang J, Spina S, Miller BL

Lancet (London, England) 2015; (386(10004)):1672-82.

Family caregivers of patients with frontotemporal dementia: An integrative review.

Caceres BA, Frank MO, Jun J, et al.

International journal of nursing studies 2016; (55()):71-84.

Young-onset frontotemporal dementia in a homozygous tau R406W mutation carrier.

Ng AS, Sias AC, Pressman PS, et al.

Annals of clinical and translational neurology 2015; (2(12)):1124-8 doi:10.1002/acn3.265.

The effects of behavioral and psychological symptoms on caregiver burden in frontotemporal dementia, Lewy body dementia, and Alzheimer's disease: clinical experience in China.

Liu S, Jin Y, Shi Z, et al.

Aging & mental health 2017; (21(6)):651-657 doi:10.1080/13607863.2016.1146871.

Altered mRNP granule dynamics in FTLD pathogenesis.

Bowden HA, Dormann D

Journal of neurochemistry 2016; (138 Suppl 1()):112-33 doi:10.1111/jnc.13601.

[New entities and the criteria of FTLD].

Otsuki M

Nihon rinsho. Japanese journal of clinical medicine 2016; (74(3)):459-65.

Chorea as a clinical feature of the basophilic inclusion body disease subtype of fused-in-sarcoma-associated frontotemporal lobar degeneration.

Kawakami I, Kobayashi Z, Arai T, et al.

Acta neuropathologica communications 2016; (4()):36 doi:10.1186/s40478-016-0304-9.

Diagnostic Accuracy of MRI and Additional [18F]FDG-PET for Behavioral Variant Frontotemporal Dementia in Patients with Late Onset Behavioral Changes.

Vijverberg EG, Wattjes MP, Dols A, et al.

Journal of Alzheimer's disease : JAD 2016; (53(4)):1287-97 doi:10.3233/JAD-160285.

FTDP-17 with Pick body-like inclusions associated with a novel tau mutation, p.E372G.

Tacik P, DeTure MA, Carlomagno Y, et al.

Brain pathology (Zurich, Switzerland) 2017; (27(5)):612-626 doi:10.1111/bpa.12428.

Late life bipolar disorder evolving into frontotemporal dementia mimic.

Dols A, Krudop W, Möller C, et al.

Neuropsychiatric disease and treatment 2016; (12()):2207-12 doi:10.2147/NDT.S99229.

Self-Consciousness Deficits in Alzheimer's Disease and Frontotemporal Dementia.

Arroyo-Anlló EM, Bouston AT, Fargeau MN, et al.

Journal of Alzheimer's disease : JAD 2017; (55(4)):1437-1443 doi:10.3233/JAD-160770.

Psychiatric Presentations of C9orf72 Mutation: What Are the Diagnostic Implications for Clinicians?

Ducharme S, Bajestan S, Dickerson BC, Voon V

The Journal of neuropsychiatry and clinical neurosciences 2017; (29(3)):195-205 doi:10.1176/appi.neuropsych.16090168.

Pharmacological Management of Psychiatric Symptoms in Frontotemporal Dementia: A Systematic Review.

Buoli M, Serati M, Caldiroli A, et al.

Journal of geriatric psychiatry and neurology 2017; (30(3)):162-169 doi:10.1177/0891988717700506.

Predicting Development of Amyotrophic Lateral Sclerosis in Frontotemporal Dementia.

Van Langenhove T, Piguet O, Burrell JR, et al.

Journal of Alzheimer's disease : JAD 2017; (58(1)):163-170 doi:10.3233/JAD-161272.

Pneumonitis and pneumonia after aspiration.

Son YG, Shin J, Ryu HG

Journal of dental anesthesia and pain medicine 2017; (17(1)):1-12 doi:10.17245/jdapm.2017.17.1.1.

The tailored activity program (TAP) to address behavioral disturbances in frontotemporal dementia: a feasibility and pilot study.

O'Connor CM, Clemson L, Brodaty H, et al.

Disability and rehabilitation 2019; (41(3)):299-310 doi:10.1080/09638288.2017.1387614.

The Genetics of Monogenic Frontotemporal Dementia.

Takada LT

Dementia & neuropsychologia 2015; (9(3)):219-229 doi:10.1590/1980-57642015DN93000003.

Asymmetry of post-mortem neuropathology in behavioural-variant frontotemporal dementia.

Irwin DJ, McMillan CT, Xie SX, et al.

Brain : a journal of neurology 2018; (141(1)):288-301 doi:10.1093/brain/awx319.

Moral processing deficit in behavioral variant frontotemporal dementia is associated with facial emotion recognition and brain changes in default mode and salience network areas.

Van den Stock J, Stam D, De Winter FL, et al.

Brain and behavior 2017; (7(12)):e00843 doi:10.1002/brb3.843.

The behavioural variant frontotemporal dementia phenocopy syndrome is a distinct entity - evidence from a longitudinal study.

Devenney E, Swinn T, Mioshi E, et al.

BMC neurology 2018; (18(1)):56 doi:10.1186/s12883-018-1060-1.

Anosognosia in degenerative brain diseases: The role of the right hemisphere and of its dominance for emotions.

Gainotti G

Brain and cognition 2018; (127()):13-22 doi:10.1016/j.bandc.2018.08.002.

Cerebrospinal fluid biomarkers predict frontotemporal dementia trajectory.

Ljubenkov PA, Staffaroni AM, Rojas JC, et al.

Annals of clinical and translational neurology 2018; (5(10)):1250-1263 doi:10.1002/acn3.643.

Tailored Activities to Reduce Neuropsychiatric Behaviors in Persons With Dementia: Case Report.

Marx KA, Scott JB, Piersol CV, Gitlin LN

The American journal of occupational therapy : official publication of the American Occupational Therapy Association 2019; (73(2)):7302205160p1-7302205160p9 doi:10.5014/ajot.2019.029546.

Promising therapies for the treatment of frontotemporal dementia clinical phenotypes: from symptomatic to disease-modifying drugs.

Logroscino G, Imbimbo BP, Lozupone M, et al.

Expert opinion on pharmacotherapy 2019; (20(9)):1091-1107 doi:10.1080/14656566.2019.1598377.

Apathy and Disinhibition Related to Neuropathology in Amnestic Versus Behavioral Dementias.

Borges LG, Rademaker AW, Bigio EH, et al.

American journal of Alzheimer's disease and other dementias 2019; (34(5)):337-343 doi:10.1177/1533317519853466.

Psychological and Cognitive Markers of Behavioral Variant Frontotemporal Dementia-A Clinical Neuropsychologist's View on Diagnostic Criteria and Beyond.

Johnen A, Bertoux M

Frontiers in neurology 2019; (10()):594 doi:10.3389/fneur.2019.00594.

Understanding Frontotemporal Disease Progression and Management Strategies.

Mulkey M

The Nursing clinics of North America 2019; (54(3)):437-448 doi:10.1016/j.cnur.2019.04.011.

Use of the CDR® plus NACC FTLD in mild FTLD: Data from the ARTFL/LEFFTDS consortium.

Miyagawa T, Brushaber D, Syrjanen J, et al.

Alzheimer's & dementia : the journal of the Alzheimer's Association 2020; (16(1)):79-90 doi:10.1016/j.jalz.2019.05.013.

New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures.

Boxer AL, Gold M, Feldman H, et al.

Alzheimer's & dementia : the journal of the Alzheimer's Association 2020; (16(1)):131-143 doi:10.1016/j.jalz.2019.06.4956.

Survival and Prognostic Factors in C9orf72 Repeat Expansion Carriers: A Systematic Review and Meta-analysis.

Glasmacher SA, Wong C, Pearson IE, Pal S

JAMA neurology 2020; (77(3)):367-376 doi:10.1001/jamaneurol.2019.3924.

Parkinsonism in frontotemporal dementias.

Rowe JB

International review of neurobiology 2019; (149()):249-275 doi:10.1016/bs.irn.2019.10.012.

Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium.

Miyagawa T, Brushaber D, Syrjanen J, et al.

Alzheimer's & dementia : the journal of the Alzheimer's Association 2020; (16(1)):106-117 doi:10.1002/alz.12033.

New-Onset Delusions Heralding an Underlying Neurodegenerative Condition: A Case Report and Review of the Literature.

Ferenczi EA, Erkkinen MG, Feany MB, et al.

The Journal of clinical psychiatry 2020; (81(2)).

Neuropsychiatric Aspects of Frontotemporal Dementia.

Younes K, Miller BL

The Psychiatric clinics of North America 2020; (43(2)):345-360 doi:10.1016/j.psc.2020.02.005.

Distinct early symptoms in neuropathologically proven frontotemporal lobar degeneration.

Kawakami I, Arai T, Shinagawa S, et al.

International journal of geriatric psychiatry 2021; (36(1)):38-45 doi:10.1002/gps.5387.

Time to diagnosis in younger-onset dementia and the impact of a specialist diagnostic service.

Loi SM, Goh AMY, Mocellin R, et al.

International psychogeriatrics 2022; (34(4)):367-375 doi:10.1017/S1041610220001489.

Cognition and behaviour in frontotemporal dementia with and without amyotrophic lateral sclerosis.

Saxon JA, Thompson JC, Harris JM, et al.

Journal of neurology, neurosurgery, and psychiatry 2020; (91(12)):1304-1311 doi:10.1136/jnnp-2020-323969.

Rates of Brain Atrophy Across Disease Stages in Familial Frontotemporal Dementia Associated With MAPT, GRN, and C9orf72 Pathogenic Variants.

Staffaroni AM, Goh SM, Cobigo Y, et al.

JAMA network open 2020; (3(10)):e2022847 doi:10.1001/jamanetworkopen.2020.22847.

GABA and glutamate deficits from frontotemporal lobar degeneration are associated with disinhibition.

Murley AG, Rouse MA, Jones PS, et al.

Brain : a journal of neurology 2020; (143(11)):3449-3462 doi:10.1093/brain/awaa305.

A Clinicopathologic Study of Movement Disorders in Frontotemporal Lobar Degeneration.

de Pablo-Fernández E, González-Herrero B, Cerdán Santacruz D, et al.

Movement disorders : official journal of the Movement Disorder Society 2021; (36(3)):632-641 doi:10.1002/mds.28356.

Young-onset frontotemporal dementia with FUS pathology.

Gowell M, Baker I, Ansorge O, Husain M

Practical neurology 2020; doi:10.1136/practneurol-2020-002730.

The Neuropsychiatric Features of Behavioral Variant Frontotemporal Dementia.

Peet BT, Castro-Suarez S, Miller BL

Advances in experimental medicine and biology 2021; (1281()):17-31 doi:10.1007/978-3-030-51140-1_2.

Comparison of clinical rating scales in genetic frontotemporal dementia within the GENFI cohort.

Peakman G, Russell LL, Convery RS, et al.

Journal of neurology, neurosurgery, and psychiatry 2022; (93(2)):158-168 doi:10.1136/jnnp-2021-326868.

Neuroimaging in Frontotemporal Dementia: Heterogeneity and Relationships with Underlying Neuropathology.

Peet BT, Spina S, Mundada N, La Joie R

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2021; (18(2)):728-752 doi:10.1007/s13311-021-01101-x.

Speech and language impairments in behavioral variant frontotemporal dementia: A systematic review.

Geraudie A, Battista P, García AM, et al.

Neuroscience and biobehavioral reviews 2021; (131()):1076-1095 doi:10.1016/j.neubiorev.2021.10.015.

Transcriptomic and Network Meta-Analysis of Frontotemporal Dementias.

Bottero V, Alrafati F, Santiago JA, Potashkin JA

Frontiers in molecular neuroscience 2021; (14()):747798 doi:10.3389/fnmol.2021.747798.

Behavioral Variant Frontotemporal Dementia and Social and Criminal Transgressions.

Mendez MF

The Journal of neuropsychiatry and clinical neurosciences 2022; (34(4)):328-340 doi:10.1176/appi.neuropsych.21080224.

Occupational Therapy Interventions for Dementia Caregivers: Scoping Review.

Martínez-Campos A, Compañ-Gabucio LM, Torres-Collado L, Garcia-de la Hera M

Healthcare (Basel, Switzerland) 2022; (10(9)) doi:10.3390/healthcare10091764.

Synaptic dysfunction in ALS and FTD: anatomical and molecular changes provide insights into mechanisms of disease.

Gelon PA, Dutchak PA, Sephton CF

Frontiers in molecular neuroscience 2022; (15()):1000183 doi:10.3389/fnmol.2022.1000183.

Behavioral variant frontotemporal dementia in patients with primary psychiatric disorder: A magnetic resonance imaging study.

Tafuri B, Filardi M, Frisullo ME, et al.

Brain and behavior 2023; (13(4)):e2896 doi:10.1002/brb3.2896.

Urine as matrix for analysis of neurofilament light chain is not suitable to distinguish frontotemporal dementia from psychiatric diseases.

van Engelen ME, Heijst H, Willemse EAJ, et al.

Brain communications 2023; (5(2)):fcad120 doi:10.1093/braincomms/fcad120.

Social Cognition in Behavioral Variant Frontotemporal Dementia and Pathological Subtypes: A Narrative Review.

Dilcher R, Malpas CB, O'Brien TJ, Vivash L

Journal of Alzheimer's disease : JAD 2023; (94(1)):19-38 doi:10.3233/JAD-221171.

Incorporating Genetic Testing Into the Care of Patients With Amyotrophic Lateral Sclerosis/Frontotemporal Degeneration Spectrum Disorders.

Chambers C, Lichten L, Crook A, et al.

Neurology. Clinical practice 2023; (13(5)):e200201 doi:10.1212/CPJ.0000000000200201.

Psychological and social impacts of frontotemporal dementia on caregivers and family members - A systematic review.

Tan YL, Lo YKJ, Ho CSH

General hospital psychiatry 2024; (86()):33-49 doi:10.1016/j.genhosppsych.2023.11.011.

Utility of the Japanese version of the Clinical Dementia Rating® plus National Alzheimer's Coordinating Centre Behaviour and Language Domains for sporadic cases of frontotemporal dementia in Japan.

Taomoto D, Sato S, Kanemoto H, et al.

Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society 2024; (24(2)):281-294 doi:10.1111/psyg.13072.

Aspiration Pneumonia.

Pan D, Chung S, Nielsen E, Niederman MS

Seminars in respiratory and critical care medicine 2024; (45(2)):237-245 doi:10.1055/s-0043-1777772.

Data-driven analysis of regional brain metabolism in behavioral frontotemporal dementia and late-onset primary psychiatric diseases with frontal lobe syndrome: A PET/MRI study.

Cagnin A, Pigato G, Pettenuzzo I, et al.

Neurobiology of aging 2024; (137()):47-54 doi:10.1016/j.neurobiolaging.2024.01.015.

VentRa: distinguishing frontotemporal dementia from psychiatric disorders.

Manera AL, Dadar M, Ducharme S, Collins DL

Brain communications 2024; (6(2)):fcae069 doi:10.1093/braincomms/fcae069.

Cerebrospinal fluid and blood neurofilament light chain levels in amyotrophic lateral sclerosis and frontotemporal degeneration: A meta-analysis.

Verde F, Licaj S, Soranna D, et al.

European journal of neurology 2024; (31(9)):e16371 doi:10.1111/ene.16371.

iPSC-induced neurons with the V337M MAPT mutation are selectively vulnerable to caspase-mediated cleavage of tau and apoptotic cell death.

Theofilas P, Wang C, Butler D, et al.

Molecular and cellular neurosciences 2024; (130()):103954 doi:10.1016/j.mcn.2024.103954.

Research trends and hotspots for frontotemporal dementia from 2000 to 2022: a bibliometric analysis.

Chen X, Chen Y, Ni B, Huang C

Frontiers in neurology 2024; (15()):1399600 doi:10.3389/fneur.2024.1399600.

Trajectories of behavior and social cognition in behavioral variant frontotemporal dementia and primary psychiatric disorders: A call for better operationalization of socioemotional changes.

Fieldhouse JLP, van Engelen ME, Handgraaf D, et al.

European journal of neurology 2024; (31(12)):e16426 doi:10.1111/ene.16426.

Neuropsychiatric Symptoms Cluster and Fluctuate Over Time in Behavioral Variant Frontotemporal Dementia.

Morrow CB, Kamath V, Dickerson BC, et al.

medRxiv : the preprint server for health sciences 2024; doi:10.1101/2024.09.26.24314180.

Neurofilament light and cognition in community-dwelling non-Hispanic Blacks.

Abdullah L, Zhang F, Hall J, O'Bryant S

Journal of Alzheimer's disease : JAD 2024; (102(1)):60-66 doi:10.1177/13872877241283693.

Motor involvement in frontotemporal lobar degeneration with TAR DNA-binding protein of 43 kDa type C.

Yamashita R, Beck G, Shigenobu K, et al.

Neuropathology : official journal of the Japanese Society of Neuropathology 2025; (45(4)):e13026 doi:10.1111/neup.13026.

Biofluid biomarkers in distinguishing young-onset dementia from primary psychiatric disorders.

Loi SM, Eratne D, Santillo AF, Velakoulis D

Current opinion in psychiatry 2025; (38(2)):134-143 doi:10.1097/YCO.0000000000000979.

Neuropsychiatric symptoms cluster and fluctuate over time in behavioral variant frontotemporal dementia.

Morrow CB, Kamath V, Dickerson BC, et al.

Psychiatry and clinical neurosciences 2025; (79(6)):327-335 doi:10.1111/pcn.13810.

Hyperorality in Frontotemporal Dementia: How Psychiatric and Neural Correlates Change During the Disease Course.

Morrow CB, Onyike C, Pantelyat A, et al.

The Journal of neuropsychiatry and clinical neurosciences 2026; (38(1)):31-37 doi:10.1176/appi.neuropsych.20240134.

The Diagnostic Landscape of Behavioral Variant Frontotemporal Dementia.

Barker MS, Manoochehri M, Huey ED

Rhode Island medical journal (2013) 2025; (108(5)):17-22.

The Evolving Role of FDG-PET in Behavioral Variant Frontotemporal Dementia: Current Applications and Future Opportunities.

Ioannidis S, Konstantinidou N, Giannakis A, et al.

International journal of molecular sciences 2025; (26(20)) doi:10.3390/ijms262010090.

Microstructural grey matter alterations in patients with behavioural variant frontotemporal dementia.

Akbarian B, Hett K, Phan T, et al.

Brain communications 2025; (7(6)):fcaf427 doi:10.1093/braincomms/fcaf427.

The Impact of Caring on Psychological Wellbeing: A Qualitative Study in Carers of People Living With Behavioural-Variant Frontotemporal Dementia.

Ocampo IM, Todd J, Wei G, Kumfor F

Journal of geriatric psychiatry and neurology 2026; (39(4)):534-548 doi:10.1177/08919887251401262.

Quantifying multimodal longitudinal brain changes in presymptomatic C9orf72 disease.

Saracino D, Cipriano L, Houot M, et al.

Alzheimer's & dementia : the journal of the Alzheimer's Association 2025; (21(12)):e70902 doi:10.1002/alz.70902.

Pathogenic or Likely Pathogenic GRN Variants Are Found in 0.1% of Parkinson's Disease Patients.

Ganoza CA, Westenberger A, Paul JJ, et al.

Movement disorders : official journal of the Movement Disorder Society 2026; (41(4)):1020-1027 doi:10.1002/mds.70161.

The impact of sex on clinical profiles of patients with behavioral variant frontotemporal dementia.

Afrooz P, St-Georges MA, Carrier T, et al.

Alzheimer's & dementia : the journal of the Alzheimer's Association 2025; (21(12)):e70996 doi:10.1002/alz.70996.

Reasons for and against presymptomatic genetic testing in frontotemporal dementia: a qualitative study.

Graafland CH, Seelaar H, Panman JL, et al.

Human genetics 2026; (145(1)):21 doi:10.1007/s00439-025-02795-1.

Impact of diagnostic genetic testing for familial dementia: experiences of patients and relatives.

van der Schaar J, Visser LNC, Asscher ECA, et al.

Alzheimer's research & therapy 2026; (18(1)).