Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
Top Authors
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Memorial Sloan Kettering Cancer Center
New York, United States
The University of Texas MD Anderson Cancer Center
Houston, United States
Leiden University Medical Center
Leiden, The Netherlands
Royal Orthopaedic Hospital
Birmingham, United Kingdom
Agios Pharmaceuticals (United States)
Cambridge, United States
Harvard University
Cambridge, United States
Istituto Ortopedico Rizzoli
Bologna, Italy
Johns Hopkins University
Baltimore, United States
German Cancer Research Center
Heidelberg, Germany
Inserm
Paris, France
References
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A pragmatic approach to the imaging and follow-up of solitary central cartilage tumours of the proximal humerus and knee.
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Clinical radiology 2019; (74(7)):517-526 doi:10.1016/j.crad.2019.01.025.
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IDH1 immunohistochemistry reactivity and mosaic IDH1 or IDH2 somatic mutations in pediatric sporadic enchondroma and enchondromatosis.
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Virchows Archiv : an international journal of pathology 2019; (475(5)):625-636 doi:10.1007/s00428-019-02606-9.
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Conventional chondrosarcoma with focal clear cell change: a clinicopathological and molecular analysis.
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Histopathology 2019; (75(6)):843-852 doi:10.1111/his.13952.
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Is the Width of a Surgical Margin Associated with the Outcome of Disease in Patients with Peripheral Chondrosarcoma of the Pelvis? A Multicenter Study.
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Survival and Prognosis of Chondrosarcoma Subtypes: SEER Database Analysis.
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Physical Function and Quality of Life After Resection of Mobile Spine Chondrosarcoma.
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Global spine journal 2019; (9(7)):743-753 doi:10.1177/2192568219830330.
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Phase I Study of the Mutant IDH1 Inhibitor Ivosidenib: Safety and Clinical Activity in Patients With Advanced Chondrosarcoma.
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Prognostic factors and survival in conventional chondrosarcoma: A single institution review.
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Amphiregulin promotes cisplatin chemoresistance by upregulating ABCB1 expression in human chondrosarcoma.
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The utility of 18F-FDG PET and PET/CT in the diagnosis and staging of chondrosarcoma: a meta-analysis.
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Targeted Next-Generation Sequencing Identifies Molecular and Genetic Events in Dedifferentiated Chondrosarcoma.
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Bladder perforation by orthopedic implants 26 years after limb-sparing surgery for left proximal femoral chondrosarcoma: A case report.
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Genomic Profiling of Low-grade Intramedullary Cartilage Tumors Can Distinguish Enchondroma From Chondrosarcoma.
Joseph NM, McGill KC, Horvai AE
The American journal of surgical pathology 2021; (45(6)):812-819 doi:10.1097/PAS.0000000000001626.
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Enchondromatosis and Growth Plate Development.
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Current osteoporosis reports 2021; (19(1)):40-49 doi:10.1007/s11914-020-00639-7.
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Chondrosarcoma local recurrence in the Cancer Registry of Norway cohort (1990-2013): Patterns and impact.
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Precision medicine for adjuvant chemotherapy of resected colorectal cancer.
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Annals of gastroenterological surgery 2020; (4(6)):635-645 doi:10.1002/ags3.12397.
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The role of imaging in differentiating low-grade and high-grade central chondral tumours.
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European journal of radiology 2021; (137()):109579 doi:10.1016/j.ejrad.2021.109579.
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Dedifferentiated chondrsarcoma: a clinicopathologic analysis of 25 cases.
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BMC musculoskeletal disorders 2021; (22(1)):189 doi:10.1186/s12891-021-04053-7.
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Chondrosarcoma.
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The Journal of the American Academy of Orthopaedic Surgeons 2021; (29(13)):553-562 doi:10.5435/JAAOS-D-20-01188.
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The usefulness of a three-dimensional printed segmental scapula prosthesis for recovering shoulder function in a patient with scapula chondrosarcoma: A case report.
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Medicine 2021; (100(8)):e24817 doi:10.1097/MD.0000000000024817.
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Traumatic Glenosphere Dissociation Following Reverse Total Shoulder Endoprosthetic Reconstruction for Proximal Humerus Periosteal Chondrosarcoma: A Case Report.
Chau MM, Marigi EM, Novaczyk ZB, et al.
Journal of orthopaedic case reports 2020; (10(8)):63-67 doi:10.13107/jocr.2020.v10.i08.1862.
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Clear Cell Chondrosarcoma with Rib Cage Metastasis: Case Report.
Caetano de Oliveira R, Reith J, Casanova J
Case reports in oncology 2021; (14(1)):239-243 doi:10.1159/000512067.
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Chondrosarcoma of the spine: a narrative review.
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The spine journal : official journal of the North American Spine Society 2021; (21(12)):2078-2096 doi:10.1016/j.spinee.2021.04.021.
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Chondrosarcoma-from Molecular Pathology to Novel Therapies.
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Cancers 2021; (13(10)) doi:10.3390/cancers13102390.
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Case Report: Reconstruction After Anterior Pubic Hemipelvectomy.
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Clinical Statistical Analysis with Comparison between Pelvic and Non-pelvic Chondrosarcoma.
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Chondrosarcoma arising in monostotic fibrous dysplasia treated with total femur resection and megaprothesis: A case report.
Wahyudi M, Alaztha Z
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Late Lung Metastasis in a Patient with a Clear Cell Chondrosarcoma: An Indication for a Life-Long Follow-Up?
West P, Jacobs C, Saerens M, et al.
Case reports in oncological medicine 2021; (2021()):7205649 doi:10.1155/2021/7205649.
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Dedifferentiated chondrosarcoma with minimal or small dedifferentiated component.
Dehner CA, Maloney N, Amini B, et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2022; (35(7)):922-928 doi:10.1038/s41379-022-01008-8.
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Chondrosarcoma of the spine-a case report.
Simon S, Resch H, Lomoschitz F, et al.
Wiener medizinische Wochenschrift (1946) 2023; (173(13-14)):334-338 doi:10.1007/s10354-021-00897-9.
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Effect of surgery and radiotherapy on overall survival in patients with chondrosarcoma: A SEER-based study.
Wang M, Song Y, Liu S, Sun W
Journal of orthopaedic surgery (Hong Kong) 2022; (30(1)):10225536221086319 doi:10.1177/10225536221086319.
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Impact of Type of Treatment Center and Access to Care on Mortality and Survival for Skull Base Chordoma and Chondrosarcoma.
Holtzman AL, Bates JE, Morris CG, et al.
Journal of neurological surgery. Part B, Skull base 2022; (83(3)):328-338 doi:10.1055/s-0040-1722228.
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Evaluation of prognostic factors affecting survival in chondrosarcoma treatment and comparison with literature.
Coşkun HS, Erdoğan F, Büyükceran İ, Dabak N
Joint diseases and related surgery 2022; (33(2)):440-448.
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Long-term follow up of patients with low-grade chondrosarcoma in the appendicular skeleton treated by extended curettage and liquid nitrogen.
El Masry AM, Azmy SI, Mustafa MAR, Abdel Aal MM
Orthopaedics & traumatology, surgery & research : OTSR 2023; (109(3)):103410 doi:10.1016/j.otsr.2022.103410.
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A new scoring system for the grading of conventional chondrosarcoma: Its clinicopathological significance.
Susuki Y, Yamada Y, Ito Y, et al.
Pathology, research and practice 2022; (238()):154125 doi:10.1016/j.prp.2022.154125.
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Bone sarcoma follow-up; a nationwide analysis of oncological events after initial treatment.
Goedhart LM, Ho VKY, Ploegmakers JJW, et al.
Journal of bone oncology 2023; (38()):100466 doi:10.1016/j.jbo.2022.100466.
PMID: 36578650 - 54
Biology and Management of High-Grade Chondrosarcoma: An Update on Targets and Treatment Options.
Tlemsani C, Larousserie F, De Percin S, et al.
International journal of molecular sciences 2023; (24(2)) doi:10.3390/ijms24021361.
PMID: 36674874 - 55
Distinct IDH1/2-associated Methylation Profile and Enrichment of TP53 and TERT Mutations Distinguish Dedifferentiated Chondrosarcoma from Conventional Chondrosarcoma.
Dermawan JKT, Nafa K, Mohanty A, et al.
Cancer research communications 2023; (3(3)):431-443 doi:10.1158/2767-9764.CRC-22-0397.
PMID: 36926116 - 56
Classification of Chondrosarcoma: From Characteristic to Challenging Imaging Findings.
Kim JH, Lee SK
Cancers 2023; (15(6)) doi:10.3390/cancers15061703.
PMID: 36980590 - 57
Multidrug resistance protein 1 silencing in osteosarcoma and chondrosarcoma cell lines.
Freund SS, Bendtsen MM, Safwat A, Joergensen PH
Journal of cancer research and therapeutics 2023; (19(Supplement)):S278-S284 doi:10.4103/jcrt.JCRT_565_19.
PMID: 37148005 - 58
Osteosarcoma and Its Advancement.
Basit Q, Qazi HS, Tanveer S
Cancer treatment and research 2023; (185()):127-139 doi:10.1007/978-3-031-27156-4_8.
PMID: 37306908 - 59
Dedifferentiated Chondrosarcoma from Molecular Pathology to Current Treatment and Clinical Trials.
Zając W, Dróżdż J, Kisielewska W, et al.
Cancers 2023; (15(15)) doi:10.3390/cancers15153924.
PMID: 37568740 - 60
Differentiation between Chondrosarcoma and Synovial Chondromatosis of the Temporomandibular Joint Using CT and MR Imaging.
Jang BG, Huh KH, Yeom HG, et al.
AJNR. American journal of neuroradiology 2023; (44(10)):1176-1183 doi:10.3174/ajnr.A7980.
PMID: 37652584 - 61
Clinico-Genomic Profiling of Conventional and Dedifferentiated Chondrosarcomas Reveals TP53 Mutation to Be Associated with Worse Outcomes.
Denu RA, Yang RK, Lazar AJ, et al.
Clinical cancer research : an official journal of the American Association for Cancer Research 2023; (29(23)):4844-4852 doi:10.1158/1078-0432.CCR-23-1703.
PMID: 37747813 - 62
Clear cell chondrosarcoma: a review of clinicopathologic characteristics, differential diagnoses, and patient management.
Alexiev BA, Vormittag-Nocito ER, Peabody TD, et al.
Human pathology 2023; (139()):126-134 doi:10.1016/j.humpath.2023.06.004.
PMID: 37805864 - 63
The significance of surveillance imaging in children with Ewing sarcoma and osteosarcoma.
Brekke SG, Lucke A, Hasle H, Baad-Hansen T
Pediatric hematology and oncology 2024; (41(4)):273-282 doi:10.1080/08880018.2024.2311407.
PMID: 38345039 - 64
FDG PET/CT and MRI Findings of Extraskeletal Myxoid Chondrosarcoma Showing a Nonmyxoid Cellular Variant.
Hirasawa M, Kikuchi Y, Sato K, et al.
Clinical nuclear medicine 2024; (49(5)):434-437 doi:10.1097/RLU.0000000000005146.
PMID: 38557577 - 65
New advances in the treatment of chondrosarcoma under the PD-1/PD-L1 pathway.
Yin J, Ren P
Journal of cancer research and therapeutics 2024; (20(2)):522-530 doi:10.4103/jcrt.jcrt_2269_23.
PMID: 38687921 - 66
Quantitative Bone SPECT/CT of Central Cartilaginous Bone Tumors: Relationship between SUVmax and Radiodensity in Hounsfield Unit.
Yoon H, Lee SK, Kim JY, Joo MW
Cancers 2024; (16(11)) doi:10.3390/cancers16111968.
PMID: 38893090 - 67
Unusual soft tissue metastases in a patient with chondrosarcoma: a case report.
Papalia GF, Ariyaratne S, Vaiyapuri S, et al.
International cancer conference journal 2024; (13(3)):313-318 doi:10.1007/s13691-024-00684-4.
PMID: 38962050 - 68
C-Reactive Protein Pretreatment-Level Evaluation with Histopathological Correlation for Chondrosarcoma Prognosis Assessment-A 15-Year Retrospective Single-Center Study.
Consalvo S, Hinterwimmer F, Stephan M, et al.
Diagnostics (Basel, Switzerland) 2024; (14(13)) doi:10.3390/diagnostics14131428.
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Radiosensitizing Effect of PARP Inhibition on Chondrosarcoma and Chondrocyte Cells Is Dependent on Radiation LET.
Gilbert A, Tudor M, Delaunay A, et al.
Biomolecules 2024; (14(9)) doi:10.3390/biom14091071.
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Surgical resection of late extrahepatic metastasis of hepatocellular carcinoma 11 years after initial diagnosis: case report and literature review.
Baz C, Nudotor R, Ian B, et al.
Journal of surgical case reports 2024; (2024(10)):rjae632 doi:10.1093/jscr/rjae632.
PMID: 39380794 - 71
Mesenchymal Chondrosarcoma of the Mandible, a Big Dilemma: Report of a Rare Case in Mesenchymal Chondrosarcoma of the Mandible-Report of a Case With Discussion of Diagnostic and Therapeutic Dilemmas.
Karimi A, Derakhshan S, Mosavat F, et al.
Case reports in dentistry 2024; (2024()):8884697 doi:10.1155/2024/8884697.
PMID: 39503009 - 72
Rare Case of Scapular Body Chondrosarcoma Treated With Limb-Salvage Partial Scapulectomy: A Case Report Highlighting Surgical Technique.
Alfadil S, Alarnous FM, Alsuwayeh F, et al.
Cureus 2024; (16(10)):e71519 doi:10.7759/cureus.71519.
PMID: 39553041 - 73
Upper limb salvage with massive intercalary allograft for humeral chondrosarcoma.
Salcedo G, Varela A, Villamues N
Acta ortopedica mexicana 2024; (38(5)):345-350.
PMID: 39586325 - 74
A case of chondrosarcoma with costovertebral location in the posterior mediastinum: Resection and stabilization.
Mutlu F, Akçalı Ö, Şanlı A
Asian cardiovascular & thoracic annals 2025; (33(1)):59-61 doi:10.1177/02184923241311937.
PMID: 39901477 - 75
Phase I Study of the Mutant IDH1 Inhibitor Ivosidenib: Long-term Safety and Clinical Activity in Patients with Conventional Chondrosarcoma.
Tap WD, Cote GM, Burris H, et al.
Clinical cancer research : an official journal of the American Association for Cancer Research 2025; (31(11)):2108-2114 doi:10.1158/1078-0432.CCR-24-4128.
PMID: 40100120 - 76
A population-based analysis of primary colonic lymphoma: Patterns of care and outcomes.
Welton LL, Kohn JF, Troester AM, et al.
Surgery 2025; (182()):109346 doi:10.1016/j.surg.2025.109346.
PMID: 40158384 - 77
Risk calculator for long-term survival prediction of spinal chordoma versus chondrosarcoma: a nationwide analysis.
Ghaith AK, Yang X, Al-Mistarehi AH, et al.
Journal of neuro-oncology 2025; (174(2)):511-525 doi:10.1007/s11060-025-05063-4.
PMID: 40295452 - 78
Exact radiological-pathological correlation of chondrosarcomas using a patient-specific 3D mold.
Lejoly M, Van Den Berghe T, Creytens D, et al.
Skeletal radiology 2025; (54(10)):2179-2190 doi:10.1007/s00256-025-04942-1.
PMID: 40358730 - 79
Musculoskeletal tumors presenting to an oncology multidisciplinary team in Northeast India.
Caleb H, Herman N, Baphiralyne W, et al.
Indian journal of cancer 2025; (62(2)):190-194 doi:10.4103/ijc.ijc_405_22.
PMID: 40788731 - 80
Anti-PD-1 antibody plus anlotinib vs. anlotinib alone in patients with refractory chondrosarcoma: A multicenter, non-randomized phase 2 FLAIL-C trial.
Li B, Xie L, Liang J, et al.
Med (New York, N.Y.) 2025; (6(11)):100809 doi:10.1016/j.medj.2025.100809.
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BCOR-Mutated Conventional and Dedifferentiated Chondrosarcoma: A Clinicopathologic Study.
Montoya-Cerrillo DM, Evans MG, Elliott A, et al.
Genes, chromosomes & cancer 2025; (64(9)):e70068 doi:10.1002/gcc.70068.
PMID: 40944348 - 82
Chondrosarcoma: Clinical Behavior, Molecular Mechanisms, and Emerging Therapeutic Strategies.
Agulnik M, Wilky BA, Thorpe Facs SW, Zuckerman LM
Critical reviews in oncology/hematology 2025; 105075 doi:10.1016/j.critrevonc.2025.105075.
PMID: 41391500 - 83
Impact of proton vs. photon radiotherapy on overall survival in the management of spinal chondrosarcoma and mortality risk prediction: A nationwide analysis.
Ghaith AK, Yang X, Khalilullah T, et al.
Neuro-oncology advances 2026; (8(1)):vdaf240 doi:10.1093/noajnl/vdaf240.
PMID: 41552408 - 84
Olutasidenib in recurrent/relapsed locally advanced or metastatic IDH1-mutated chondrosarcoma: phase 1b/2 trial.
Jones RL, Groisberg R, Blay JY, et al.
Nature communications 2026; (17(1)).
PMID: 41611702 - 85
Chemotherapy in dedifferentiated chondrosarcoma: From neoadjuvant to palliative treatment options.
Remiszewski P, Wąż J, Falkowski S, et al.
Critical reviews in oncology/hematology 2026; (223()):105297 doi:10.1016/j.critrevonc.2026.105297.
PMID: 41895355