Research & Literature

IgG4-related ophthalmic disease. Part I: background and pathology.

McNab AA, McKelvie P

Ophthalmic plastic and reconstructive surgery 2015; (31(2)):83-8 doi:10.1097/IOP.0000000000000363.

IgG4-Related Ophthalmic Disease. Part II: Clinical Aspects.

McNab AA, McKelvie P

Ophthalmic plastic and reconstructive surgery 2015; (31(3)):167-78 doi:10.1097/IOP.0000000000000364.

Clinical and Imaging Features of Lacrimal Gland Involvement in Granulomatosis with Polyangiitis.

Tan LT, Davagnanam I, Isa H, et al.

Ophthalmology 2015; (122(10)):2125-9.

The many facets of dacryoadenitis.

Mombaerts I

Current opinion in ophthalmology 2015; (26(5)):399-407 doi:10.1097/ICU.0000000000000183.

Management of orbital IgG4-related disease.

Glass LR, Freitag SK

Current opinion in ophthalmology 2015; (26(6)):491-7 doi:10.1097/ICU.0000000000000204.

Idiopathic Dacryoadenitis: Clinical Features, Histopathology, and Treatment Outcomes.

Andrew NH, Kearney D, Sladden N, et al.

American journal of ophthalmology 2016; (163()):148-153.e1 doi:10.1016/j.ajo.2015.11.032.

Bilateral IgG4-related ophthalmic disease: a strong indication for systemic imaging.

Wu A, Andrew NH, McNab AA, Selva D

The British journal of ophthalmology 2016; (100(10)):1409-11 doi:10.1136/bjophthalmol-2015-307437.

Orbital inflammation: Biopsy first.

Mombaerts I, Rose GE, Garrity JA

Survey of ophthalmology 2016; (61(5)):664-9.

Relationship between dacryoadenitis subtype of idiopathic orbital inflammatory pseudotumor and paranasal sinusitis.

Li J, Ge X, Ma JM

International journal of ophthalmology 2016; (9(3)):444-7 doi:10.18240/ijo.2016.03.21.

Orbital Involvement and Ocular Surface Changes in IgG4-Related Systemic Disease.

Kocabeyoglu S, Karadag O, Mocan MC, et al.

Cornea 2016; (35(11)):1449-1453 doi:10.1097/ICO.0000000000000965.

Bilateral Dacryoadenitis: Don't Forget Tuberculosis!

Ruman-Colombier M, Crisinel PA, Cohen-Dumani N, et al.

The Pediatric infectious disease journal 2017; (36(1)):117-119 doi:10.1097/INF.0000000000001365.

Granulomatosis with polyangiitis confined to lacrimal gland, a case report.

Zuazo F, González M, Abdala A, et al.

Archivos de la Sociedad Espanola de Oftalmologia 2017; (92(11)):543-546 doi:10.1016/j.oftal.2016.11.006.

Long-Term Outcomes of Eye-Sparing Surgery for Adenoid Cystic Carcinoma of Lacrimal Gland.

Han J, Kim YD, Woo KI, Sobti D

Ophthalmic plastic and reconstructive surgery 2018; (34(1)):74-78 doi:10.1097/IOP.0000000000000877.

Ophthalmic manifestations in IgG4-related disease: Clinical presentation and response to treatment in a French case-series.

Ebbo M, Patient M, Grados A, et al.

Medicine 2017; (96(10)):e6205 doi:10.1097/MD.0000000000006205.

Consensus on Diagnostic Criteria of Idiopathic Orbital Inflammation Using a Modified Delphi Approach.

Mombaerts I, Bilyk JR, Rose GE, et al.

JAMA ophthalmology 2017; (135(7)):769-776 doi:10.1001/jamaophthalmol.2017.1581.

Lacrimal gland development: From signaling interactions to regenerative medicine.

Garg A, Zhang X

Developmental dynamics : an official publication of the American Association of Anatomists 2017; (246(12)):970-980 doi:10.1002/dvdy.24551.

Lacrimal gland abscesses: Case series and literature review.

Savoie B, Rodgers R, Gorski M

Orbit (Amsterdam, Netherlands) 2017; (36(6)):428-432 doi:10.1080/01676830.2017.1337205.

The role of biopsy in lacrimal gland inflammation: A clinicopathologic study.

Luemsamran P, Rootman J, White VA, et al.

Orbit (Amsterdam, Netherlands) 2017; (36(6)):411-418 doi:10.1080/01676830.2017.1352608.

Gene Expression Profiling and Heterogeneity of Nonspecific Orbital Inflammation Affecting the Lacrimal Gland.

Rosenbaum JT, Choi D, Harrington CA, et al.

JAMA ophthalmology 2017; (135(11)):1156-1162 doi:10.1001/jamaophthalmol.2017.3458.

Clinicoserological factors associated with response to steroid treatment and recurrence in patients with IgG4-related ophthalmic disease.

Hong JW, Kang S, Song MK, et al.

The British journal of ophthalmology 2018; (102(11)):1591-1595 doi:10.1136/bjophthalmol-2017-311519.

Immunoglobulin G4-related dacyroadenitis presenting as bilateral chorioretinal folds from severely enlarged lacrimal glands.

Kurokawa T, Hamano H, Muraki T, et al.

American journal of ophthalmology case reports 2018; (9()):88-92 doi:10.1016/j.ajoc.2018.01.017.

Man with a Swollen Eye: Nonspecific Orbital Inflammation in an Adult in the Emergency Department.

Zhang XC, Statler B, Suner S, et al.

The Journal of emergency medicine 2018; (55(1)):110-113 doi:10.1016/j.jemermed.2018.04.001.

Pleomorphic adenoma of the lacrimal gland: A review with updates on malignant transformation and molecular genetics.

Harrison W, Pittman P, Cummings T

Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society 2018; (32(1)):13-16 doi:10.1016/j.sjopt.2018.02.014.

Grading Severity and Activity in Thyroid Eye Disease.

Dolman PJ

Ophthalmic plastic and reconstructive surgery 2018; (34(4S Suppl 1)):S34-S40 doi:10.1097/IOP.0000000000001150.

Clinical presentation and treatment outcomes of primary ocular adnexal MALT lymphoma in Thailand.

Seresirikachorn K, Norasetthada L, Ausayakhun S, et al.

Blood research 2018; (53(4)):307-313 doi:10.5045/br.2018.53.4.307.

The treatment outcomes in IgG4-related orbital disease: a systematic review of the literature.

Detiger SE, Karim AF, Verdijk RM, et al.

Acta ophthalmologica 2019; (97(5)):451-459 doi:10.1111/aos.14048.

Clinicopathologic features of biopsied lacrimal gland masses in 95 Korean patients.

Ahn C, Kang S, Sa HS

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2019; (257(7)):1527-1533 doi:10.1007/s00417-019-04327-w.

Clinical characteristics, histopathology, and treatment outcomes in adult and pediatric patients with nonspecific orbital inflammation.

Eshraghi B, Sonbolestan SA, Abtahi MA, Mirmohammadsadeghi A

Journal of current ophthalmology 2019; (31(3)):327-334 doi:10.1016/j.joco.2019.03.004.

Tuberculosis presenting as dacryoadenitis in the USA.

Powers HR, Diaz MA, Mendez JC

BMJ case reports 2019; (12(11)) doi:10.1136/bcr-2019-231694.

Lymphoma of the Lacrimal Gland - An International Multicenter Retrospective Study.

Vest SD, Mikkelsen LH, Holm F, et al.

American journal of ophthalmology 2020; (219()):107-120 doi:10.1016/j.ajo.2020.06.015.

Acute dacryoadenitis in a patient with SARS-CoV-2 infection.

Martínez Díaz M, Copete Piqueras S, Blanco Marchite C, Vahdani K

Orbit (Amsterdam, Netherlands) 2022; (41(3)):374-377 doi:10.1080/01676830.2020.1867193.

Long-term follow up of systemic rituximab therapy as first-line and salvage therapy for idiopathic orbital inflammation and review of the literature.

Abou-Hanna JJ, Tiu Teo HM, Thangavel R, et al.

Orbit (Amsterdam, Netherlands) 2022; (41(3)):297-304 doi:10.1080/01676830.2021.1874424.

Masses of the Lacrimal Gland: Evaluation and Treatment.

Kim JS, Liss J

Journal of neurological surgery. Part B, Skull base 2021; (82(1)):100-106 doi:10.1055/s-0040-1722700.

Conjunctival Infiltration in a Child as a Rare Manifestation of IgG4-Related Disease.

Qi SR, Hébert M, You E, et al.

Cornea 2022; (41(4)):496-498 doi:10.1097/ICO.0000000000002773.

Clinical features and symptoms of IgG4-related ophthalmic disease: a multicenter study.

Goto H, Ueda SI, Nemoto R, et al.

Japanese journal of ophthalmology 2021; (65(5)):651-656 doi:10.1007/s10384-021-00847-3.

Refractory Dry Eye Syndrome after Transconjunctival Excision of the Palpebral Lobe of the Lacrimal Gland.

Lee YJ, Choi HS, Park SJ, et al.

Medicina (Kaunas, Lithuania) 2021; (57(6)) doi:10.3390/medicina57060608.

[Idiopathic orbital inflammation].

Lieb WE

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 2021; (118(8)):777-786 doi:10.1007/s00347-021-01459-5.

Bilateral lacrimal gland lymphoma: Case report and literature review.

Ngoc LB, Doan NV, Ngan VK, et al.

Radiology case reports 2022; (17(1)):240-244 doi:10.1016/j.radcr.2021.10.046.

Ophthalmic involvement disparities in clinical characteristics of IgG4-related disease: a retrospective study of 573 patients.

Gan L, Luo X, Fei Y, et al.

BMC ophthalmology 2021; (21(1)):447 doi:10.1186/s12886-021-02210-z.

Long-Term Outcomes of IgG4-Related Ophthalmic Disease in a Chinese IgG4-Related Disease Cohort.

Gan L, Luo X, Fei Y, et al.

Frontiers in medicine 2021; (8()):784520 doi:10.3389/fmed.2021.784520.

Clinical, Radiological and Histopathological Features of Patients With Lacrimal Gland Enlargement.

Jamshidian Tehrani M, Asadi Khameneh E, Pourseyed Iazarjani SZ, et al.

Archives of Iranian medicine 2021; (24(12)):910-915 doi:10.34172/aim.2021.136.

Lacrimal Gland Lesions Biopsied in a Tertiary Eye Center in Saudi Arabia: A Clinical, Radiological, Surgical, and Histological Review.

Alturkistany W, Althaqib R, Alsulaiman N, et al.

Clinical ophthalmology (Auckland, N.Z.) 2022; (16()):191-200 doi:10.2147/OPTH.S331252.

Cases with IgG4-related ophthalmic disease with mass lesions surrounding the optic nerve.

Hamaoka S, Takahira M, Kawano M, et al.

American journal of ophthalmology case reports 2022; (25()):101324 doi:10.1016/j.ajoc.2022.101324.

Pathological count of IgG4-positive plasmacytes suggests extraophthalmic involvement and relapse in patients with IgG4-related ophthalmic disease: a retrospective study.

Yuan Y, Meng F, Ren H, et al.

Arthritis research & therapy 2022; (24(1)):80 doi:10.1186/s13075-022-02757-2.

Recurrent lacrimal gland pleomorphic adenoma.

Reilly S, Ellard R, O'Sullivan M, et al.

Orbit (Amsterdam, Netherlands) 2023; (42(6)):635-640 doi:10.1080/01676830.2022.2064515.

A Rare Case of Neurosarcoidosis Overlapped with Sjogren's Syndrome.

Cai W, Li R, He J, et al.

Journal of clinical medicine 2022; (11(19)) doi:10.3390/jcm11195709.

Long-Term Follow-Up in IgG4-Related Ophthalmic Disease: Serum IgG4 Levels and Their Clinical Relevance.

Chou WY, Tsai CY, Tsai CC

Journal of personalized medicine 2022; (12(12)) doi:10.3390/jpm12121963.

A case report: An unusual presentation of adenoid cystic carcinoma of the lacrimal gland.

Liang M, Yu Z, Wang F

Medicine 2023; (102(13)):e33446 doi:10.1097/MD.0000000000033446.

Atypical presentation of bilateral Epstein-Barr virus dacryoadenitis: a case report of corticosteroid resistant orbital inflammation.

Tan CH, Tauchi-Nishi PS, Sweeney AR

Journal of ophthalmic inflammation and infection 2023; (13(1)):24 doi:10.1186/s12348-023-00349-y.

Ocular Surface Evaluation in Immunoglobulin G4-Related Ophthalmic Disease.

Lai KKH, Liao X, Aljufairi FMAA, et al.

American journal of ophthalmology 2023; (256()):90-96 doi:10.1016/j.ajo.2023.07.031.

Diagnostic Utility of Minor Salivary Gland Biopsy for Primary Sjögren Syndrome in Patients With Negative Anti-SSA Antibodies.

Goel RR, Jeranko M, Jones L, et al.

Cureus 2023; (15(9)):e46207 doi:10.7759/cureus.46207.

Advances in imaging of the lacrimal gland in Sjögren's syndrome: A narrative review.

Zhong W, Zhang H, Ran H

Journal of clinical ultrasound : JCU 2024; (52(1)):68-77 doi:10.1002/jcu.23596.

Systemic Involvement in Immunoglobulin G4-Related Ophthalmic Disease.

Lai KKH, Aljufairi FMAA, Sebastian JU, et al.

Ocular immunology and inflammation 2024; (32(8)):1852-1858 doi:10.1080/09273948.2023.2280709.

Repeated Lacrimal Gland Biopsies.

Kaushik M, Vahdani K, Neumann I, et al.

Ophthalmic plastic and reconstructive surgery 2024; (40(4)):440-444 doi:10.1097/IOP.0000000000002614.

Mucosa-associated lymphoid tissue lymphoma of the lacrimal gland: A case report and literature review.

Zhong Q, Yan Y, Li S

Medicine 2024; (103(21)):e38303 doi:10.1097/MD.0000000000038303.

The 2023 revised diagnostic criteria for IgG4-related ophthalmic disease.

Takahira M, Goto H, Azumi A

Japanese journal of ophthalmology 2024; (68(4)):293-301 doi:10.1007/s10384-024-01072-4.

Assessing IgG4-related ophthalmic disease and its mimics: a comparison of ACR/EULAR, organ-specific and revised comprehensive diagnostic criteria.

Bakshi N, Aggarwal A, Dhawan S, et al.

Journal of clinical pathology 2025; (78(8)):554-561 doi:10.1136/jcp-2024-209552.

Primary Ductal Her-2 Positive Adenocarcinoma of Salivary Gland: A Long Follow-Up Case Report and Review of the Literature.

Deantoni CL, Midulla M, Mirabile A, et al.

Case reports in ophthalmological medicine 2024; (2024()):4410206 doi:10.1155/2024/4410206.

Magnetic resonance diffusion-weighted imaging in lacrimal gland lymphoma versus inflammation: A comparative study.

Landau-Prat D, Shemesh R, Shalev D, et al.

Indian journal of ophthalmology 2024; (72(10)):1448-1452 doi:10.4103/IJO.IJO_2109_23.

Treatment of Idiopathic Inflammatory Orbital Syndrome (IOIS) With Prominent Lacrimal Gland Involvement Using Oral Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).

Ling HM, Chow KM

Cureus 2024; (16(8)):e67981 doi:10.7759/cureus.67981.

The 2023 revised diagnostic criteria for IgG4-related dacryoadenitis and sialadenitis.

Kanda M, Nagahata K, Moriyama M, et al.

Modern rheumatology 2025; (35(3)):542-547 doi:10.1093/mr/roae096.

Late onset paediatric dacryoadenitis associated with SARS-CoV-2 confirmed by histological analysis.

Yokoyama K, Sato Y, Suimon Y, Kase S

BMJ case reports 2024; (17(12)) doi:10.1136/bcr-2023-257615.

Guidelines for the standardized diagnosis and treatment of non-specific orbital inflammation (2024).

Shao Y, Ma JM, Yang HS,

International journal of ophthalmology 2024; (17(12)):2203-2213 doi:10.18240/ijo.2024.12.07.

Bilateral sequential bacterial dacryoadenitis with abscess- a case report.

Lam L, Pietris J, Quigley C, et al.

BMC ophthalmology 2025; (25(1)):227 doi:10.1186/s12886-025-04063-2.

Idiopathic Posterior Scleritis Complicated by Optic Perineuritis and Ocular Motility Disorder Successfully Controlled with Adalimumab: A Case Report.

Numaga Y, Aoyama Y, Tanaka R

Case reports in ophthalmology 2025; (16(1)):916-925 doi:10.1159/000549539.

Head and neck manifestations of IgG4-related disease: current understanding.

Takano K

Japanese journal of radiology 2026; (44(5)):856-865 doi:10.1007/s11604-025-01934-y.

Gonococcal Dacryoadenitis: A Case Report.

Hains L, Quigley C, Selva D

Case reports in ophthalmology 2026; (17(1)):275-280 doi:10.1159/000550844.

Management of IgG4-Related Disease.

Hernández-Molina G, Anaya-Macías BU, Martín-Nares E

Current rheumatology reports 2026; (28(1)).

Atypical presentation of Epstein-Barr virus infectious mononucleosis with bilateral dacryoadenitis in an elderly patient: a case report.

Mahfoud N, Ali M, Abboud M

Journal of medical case reports 2026; (20(1)).

The Lacrimal System.

Kumar S, Kinde B, Pham N, Fischbein N

Radiologic clinics of North America 2026; (64(4)):675-690 doi:10.1016/j.rcl.2026.02.006.

Atypical imaging characteristics in patients with epithelial tumors of lacrimal gland and impact on initial surgical planning.

Esmaeli B, Lu T, Ketonen L, Debnam JM

Frontiers in oncology 2026; (16()):1852743 doi:10.3389/fonc.2026.1852743.