Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
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Boston Children's Hospital
Boston, United States
Rigshospitalet
Copenhagen, Denmark
University of Toronto
Toronto, Canada
IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola
Bologna, Italy
Hôpital Beaujon
Clichy, France
Hôpital Necker-Enfants Malades
Paris, France
Cincinnati Children's Hospital Medical Center
Cincinnati, United States
Radboud University Nijmegen
Nijmegen, The Netherlands
Innsbruck Medical University
Innsbruck, Austria
Inserm
Paris, France
References
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Taurolidine-citrate-heparin lock reduces catheter-related bloodstream infections in intestinal failure patients dependent on home parenteral support: a randomized, placebo-controlled trial.
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Acute impact of home parenteral nutrition in patients with late-stage cancer on family caregivers: preliminary data.
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Long-term outcomes of pediatric intestinal failure.
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Seminars in pediatric surgery 2017; (26(5)):328-335 doi:10.1053/j.sempedsurg.2017.09.006.
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Intestinal epithelial cell polarity defects in disease: lessons from microvillus inclusion disease.
Schneeberger K, Roth S, Nieuwenhuis EES, Middendorp S
Disease models & mechanisms 2018; (11(2)) doi:10.1242/dmm.031088.
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The hepatobiliary complications of malnutrition and nutritional support in adults.
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Irish journal of medical science 2019; (188(1)):109-117 doi:10.1007/s11845-018-1836-8.
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Is maintenance of the ileocecal valve important to the intestinal adaptation mechanisms in a weaning rat model of short bowel?
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Pediatric surgery international 2018; (34(11)):1215-1224 doi:10.1007/s00383-018-4333-2.
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Taurolidine-Citrate Line Locks Prevent Recurrent Central Line-Associated Bloodstream Infection in Pediatric Patients.
Clark JE, Graham N, Kleidon T, Ullman A
The Pediatric infectious disease journal 2019; (38(1)):e16-e18 doi:10.1097/INF.0000000000002191.
PMID: 30204661 - 18
Organization and outcomes of multidisciplinary intestinal failure teams.
Javid PJ, Wendel D, Horslen SP
Seminars in pediatric surgery 2018; (27(4)):218-222 doi:10.1053/j.sempedsurg.2018.07.005.
PMID: 30342595 - 19
Surgeon's perspective on short bowel syndrome: Where are we?
Marino IR, Lauro A
World journal of transplantation 2018; (8(6)):198-202 doi:10.5500/wjt.v8.i6.198.
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Imaging of adult intestinal failure.
Smith J, Godfrey E, Bowden D, et al.
Clinical radiology 2019; (74(8)):603-612 doi:10.1016/j.crad.2018.12.007.
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Autologous intestinal reconstruction: a single institution study of the serial transverse enteroplasty (STEP) and the longitudinal intestinal lengthening and tailoring (LILT).
Shah AA, Petrosyan M, Franklin AL, et al.
Pediatric surgery international 2019; (35(6)):649-655 doi:10.1007/s00383-019-04468-3.
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Pediatric Intestinal Failure: A Review of the Scope of Disease and a Regional Model of a Multidisciplinary Care Team.
Mangalat N
Missouri medicine 2019; (116(2)):129-133.
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Hepatobiliary Complications of Chronic Intestinal Failure.
Van Gossum A, Demetter P
Gastroenterology clinics of North America 2019; (48(4)):551-564 doi:10.1016/j.gtc.2019.08.008.
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Controversy in Nutrition Recommendations for Short Bowel Syndrome: How Type of SBS Impacts Response.
Austin K, Bonnes S, Daniel H
Current gastroenterology reports 2019; (21(12)):64 doi:10.1007/s11894-019-0731-4.
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Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia 2019; (36(4)):414-420 doi:10.4067/S0716-10182019000400414.
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New Insights Into Intestinal Failure-Associated Liver Disease in Children.
Khalaf RT, Sokol RJ
Hepatology (Baltimore, Md.) 2020; (71(4)):1486-1498 doi:10.1002/hep.31152.
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Multidisciplinary Management in Pediatric Ultrashort Bowel Syndrome.
Belza C, Wales PW
Journal of multidisciplinary healthcare 2020; (13()):9-17 doi:10.2147/JMDH.S236130.
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Osteoporosis and Hepatic Steatosis: 2 Closely Related Complications in Short-Bowel Syndrome.
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JPEN. Journal of parenteral and enteral nutrition 2020; (44(7)):1271-1279 doi:10.1002/jpen.1802.
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Current opinion in gastroenterology 2020; (36(3)):223-229 doi:10.1097/MOG.0000000000000631.
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Etiology of and predictive factors for chronic intestinal failure requiring long term parenteral support in the last two decades: A retrospective study.
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Clinical nutrition ESPEN 2020; (37()):168-172 doi:10.1016/j.clnesp.2020.02.019.
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Impact of locking solutions on conditioning biofilm formation in tunnelled haemodialysis catheters and inflammatory response activation.
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The journal of vascular access 2021; (22(3)):370-379 doi:10.1177/1129729820942040.
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Postsurgical Intestinal Rehabilitation Using Semisynthetic Glucagon-Like Peptide-2 Analogue (sGLP-2) at a Referral Center: Can Patients Achieve Parenteral Nutrition and sGLP-2 Independency?
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JPEN. Journal of parenteral and enteral nutrition 2021; (45(5)):1072-1082 doi:10.1002/jpen.1983.
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Moving on: How to switch young people with chronic intestinal failure from pediatric to adult care. a position statement by italian society of gastroenterology and hepatology and nutrition (SIGENP) and italian society of artificial nutrition and metabolism (SINPE).
Diamanti A, Capriati T, Lezo A, et al.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2020; (52(10)):1131-1136 doi:10.1016/j.dld.2020.07.032.
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Fish Oil Emulsion Reduces Liver Injury and Liver Transplantation in Children with Intestinal Failure-Associated Liver Disease: A Multicenter Integrated Study.
Gura KM, Premkumar MH, Calkins KL, Puder M
The Journal of pediatrics 2021; (230()):46-54.e2 doi:10.1016/j.jpeds.2020.09.068.
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Micronutrient deficiencies in pediatric short bowel syndrome: a 10-year review from an intestinal rehabilitation center in China.
Feng H, Zhang T, Yan W, et al.
Pediatric surgery international 2020; (36(12)):1481-1487 doi:10.1007/s00383-020-04764-3.
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Stem cell and niche regulation in human short bowel syndrome.
Gazit VA, Swietlicki EA, Liang MU, et al.
JCI insight 2020; (5(23)).
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Nutritional Care for Patients with Intestinal Failure.
Matarese LE, Harvin G
Gastroenterology clinics of North America 2021; (50(1)):201-216 doi:10.1016/j.gtc.2020.10.004.
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Phenotypic switch of smooth muscle cells in paediatric chronic intestinal pseudo-obstruction syndrome.
Martire D, Garnier S, Sagnol S, et al.
Journal of cellular and molecular medicine 2021; (25(8)):4028-4039 doi:10.1111/jcmm.16367.
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Vitamin D deficiency in patients with chronic intestinal failure on home parenteral nutrition.
Rondaij T, Kozjek NR, Popovič P, Jordan T
Clinical nutrition ESPEN 2021; (42()):258-261 doi:10.1016/j.clnesp.2021.01.026.
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Genetic Enteropathies Linked to Epithelial Structural Abnormalities and Enteroendocrine Deficiency: A Systematic Review.
Caralli M, Roman C, Coste ME, et al.
Journal of pediatric gastroenterology and nutrition 2021; (72(6)):826-832 doi:10.1097/MPG.0000000000003049.
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Trends in Pediatric Intestinal Failure: A Multicenter, Multinational Study.
Gattini D, Roberts AJ, Wales PW, et al.
The Journal of pediatrics 2021; (237()):16-23.e4 doi:10.1016/j.jpeds.2021.06.025.
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Intestinal iatrogenic hyperadaptation in patients with short bowel syndrome and Crohn's disease: Is this an indication for mandatory lifelong injections of teduglutide?
Mazzuoli S, Regano N, Lamacchia S, et al.
Nutrition (Burbank, Los Angeles County, Calif.) 2021; (91-92()):111396 doi:10.1016/j.nut.2021.111396.
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ESPEN practical guideline: Clinical nutrition in chronic intestinal failure.
Cuerda C, Pironi L, Arends J, et al.
Clinical nutrition (Edinburgh, Scotland) 2021; (40(9)):5196-5220 doi:10.1016/j.clnu.2021.07.002.
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Use of Intravenous Soybean and Fish Oil Emulsions in Pediatric Intestinal Failure-Associated Liver Disease: A Multicenter Integrated Analysis Report on Extrahepatic Adverse Events.
Gura KM, Calkins KL, Premkumar MH, Puder M
The Journal of pediatrics 2022; (241()):173-180.e1 doi:10.1016/j.jpeds.2021.10.030.
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The experience and outcomes of multidisciplinary clinical pharmacist-led parenteral nutrition service for individuals with intestinal failure in a center without home parenteral nutrition.
Shafiekhani M, Nikoupour H, Mirjalili M
European journal of clinical nutrition 2022; (76(6)):841-847 doi:10.1038/s41430-021-01048-4.
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Male gender is associated with informal caregiver burden in patients with chronic intestinal failure treated with home parenteral nutrition.
Castinel J, Pellet G, Laharie D, et al.
JPEN. Journal of parenteral and enteral nutrition 2022; (46(7)):1593-1601 doi:10.1002/jpen.2340.
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Mechanical Complications in Central Lines Using Taurolidine Versus Ethanol Lock Therapy in Children With Intestinal Failure.
Strauss J, Boctor DL, Silverman JA, Casey L
Journal of pediatric gastroenterology and nutrition 2022; (74(6)):776-781 doi:10.1097/MPG.0000000000003434.
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Meta-analysis of the efficacy of taurolidine in reducing catheter-related bloodstream infections for patients receiving parenteral nutrition.
Vernon-Roberts A, Lopez RN, Frampton CM, Day AS
JPEN. Journal of parenteral and enteral nutrition 2022; (46(7)):1535-1552 doi:10.1002/jpen.2363.
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Chronic intestinal failure: an overview and future perspectives.
López Romero-Salazar F, Martínez Montiel P, Lal S
Revista espanola de enfermedades digestivas 2022; (114(5)):251-253 doi:10.17235/reed.2022.8827/2022.
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Abatacept to treat chronic intestinal pseudo-obstruction in five systemic sclerosis patients with a description of the index case.
Vigone B, Beretta L
Journal of scleroderma and related disorders 2019; (4(1)):NP5-NP9 doi:10.1177/2397198318766819.
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Chronic Intestinal Failure in Children: An International Multicenter Cross-Sectional Survey.
Lezo A, Diamanti A, Marinier EM, et al.
Nutrients 2022; (14(9)) doi:10.3390/nu14091889.
PMID: 35565856 - 52
Management of Central Venous Catheters in Children and Adults on Home Parenteral Nutrition: A French Survey of Current Practice.
Gotchac J, Poullenot F, Guimber D, et al.
Nutrients 2022; (14(12)) doi:10.3390/nu14122532.
PMID: 35745262 - 53
Long-term home parenteral nutrition and profile of amino acids in serum and their loss in urine.
Dastych M, Šenkyřík M, Mikušková A, Dastych M
The British journal of nutrition 2023; (129(9)):1537-1542 doi:10.1017/S0007114522002008.
PMID: 35912675 - 54
Medical and Surgical Aspects of Intestinal Failure in the Child.
Wendel D, Javid PJ
The Surgical clinics of North America 2022; (102(5)):861-872 doi:10.1016/j.suc.2022.07.015.
PMID: 36209751 - 55
Enteric Neuromyopathies: Highlights on Genetic Mechanisms Underlying Chronic Intestinal Pseudo-Obstruction.
Bianco F, Lattanzio G, Lorenzini L, et al.
Biomolecules 2022; (12(12)) doi:10.3390/biom12121849.
PMID: 36551277 - 56
Histopathological, Ultrastructural, and Immunohistochemical Findings in MYH11-Variant Visceral Myopathy.
Kapur RP
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2023; (26(1)):39-51 doi:10.1177/10935266221128133.
PMID: 36571289 - 57
The Role of a Colon-in-Continuity in Short Bowel Syndrome.
Verbiest A, Jeppesen PB, Joly F, Vanuytsel T
Nutrients 2023; (15(3)) doi:10.3390/nu15030628.
PMID: 36771335 - 58
Quality of Life in the Management of Home Parenteral Nutrition.
Schönenberger KA, Reber E, Huwiler VV, et al.
Annals of nutrition & metabolism 2023; (79(3)):326-333 doi:10.1159/000530082.
PMID: 36934718 - 59
Pathophysiology of gastrointestinal acute graft-versus-host disease and the potential role of glucagon-like peptide 2.
Zeiser R, Chen YB, Youssef NN, Ayuk F
British journal of haematology 2023; (201(4)):620-627 doi:10.1111/bjh.18778.
PMID: 36965050 - 60
Treatment of short bowel syndrome: Breaking the therapeutic ceiling?
Wauters L, Joly F
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 2023; (38 Suppl 1()):S76-S87 doi:10.1002/ncp.10974.
PMID: 37115030 - 61
Definition, classification, and causes of short bowel syndrome.
Pironi L
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 2023; (38 Suppl 1()):S9-S16 doi:10.1002/ncp.10955.
PMID: 37115031 - 62
Long-term treatment with teduglutide: a 48-week open-label single-center clinical trial in children with short bowel syndrome.
Lambe C, Talbotec C, Kapel N, et al.
The American journal of clinical nutrition 2023; (117(6)):1152-1163 doi:10.1016/j.ajcnut.2023.02.019.
PMID: 37270289 - 63
Nutritional management of a patient with chronic intestinal failure and hemodialysis receiving teduglutide: A case report.
Florencio Ojeda L, Domínguez Rabadán R, Laínez López M, et al.
Nutrition (Burbank, Los Angeles County, Calif.) 2023; (113()):112137 doi:10.1016/j.nut.2023.112137.
PMID: 37481817 - 64
ESPEN guideline on chronic intestinal failure in adults - Update 2023.
Pironi L, Cuerda C, Jeppesen PB, et al.
Clinical nutrition (Edinburgh, Scotland) 2023; (42(10)):1940-2021 doi:10.1016/j.clnu.2023.07.019.
PMID: 37639741 - 65
Chronic intestinal pseudo-obstruction due to adult-onset acquired isolated hypoganglionosis with muscular atrophy in the small intestine: a case report and review of literature.
Tayama S, Furuta Y, Morito M, et al.
Clinical journal of gastroenterology 2024; (17(2)):244-252 doi:10.1007/s12328-023-01902-x.
PMID: 38193986 - 66
Intestinal Rehabilitation Program for Adult Patients with Intestinal Failure: A 20-Year Analysis of Outcomes in the Single-Center Experience at a Tertiary Hospital.
Im KM, Chung JH
Digestive diseases and sciences 2024; (69(5)):1770-1777 doi:10.1007/s10620-024-08285-0.
PMID: 38446306 - 67
The Anxiety Burden in Patients with Chronic Intestinal Failure on Long-Term Parenteral Nutrition and in Their Caregivers.
Santarpia L, Orefice R, Alfonsi L, et al.
Nutrients 2024; (16(8)) doi:10.3390/nu16081168.
PMID: 38674859 - 68
Pediatric Intestinal Failure Associated Eating Disorder: An Overview of the Importance of Oral Feeding in a Population at Risk for Feeding Difficulties.
Boctor DL, Fenton TR, Goulet O, Lambe C
Gastroenterology clinics of North America 2024; (53(2)):309-327 doi:10.1016/j.gtc.2023.12.003.
PMID: 38719381 - 69
Vascular rehabilitation in children with chronic intestinal failure reduces the risk of central-line associated bloodstream infections and catheter replacements.
Hilberath J, Sieverding L, Urla C, et al.
Clinical nutrition (Edinburgh, Scotland) 2024; (43(7)):1636-1641 doi:10.1016/j.clnu.2024.05.026.
PMID: 38801807 - 70
Transition from pediatric to adult care in patients with chronic intestinal failure on home parenteral nutrition: How to do it right?
Demirok A, Benninga MA, Diamanti A, et al.
Clinical nutrition (Edinburgh, Scotland) 2024; (43(8)):1844-1851 doi:10.1016/j.clnu.2024.06.019.
PMID: 38959661 - 71
Management of Short Bowel Syndrome With Chronic Intestinal Failure: A Single-Center Experience in Portugal.
Santos MD, Magalhães V, Loureiro L, et al.
Cureus 2024; (16(6)):e63443 doi:10.7759/cureus.63443.
PMID: 39077232 - 72
The ratio of remaining to expected small bowel length predicts enteral autonomy in pediatric patients with short bowel syndrome.
Chang CW, Yeh PJ, Lai HH, et al.
Biomedical journal 2025; (48(4)):100791 doi:10.1016/j.bj.2024.100791.
PMID: 39305993 - 73
Survival and parenteral nutrition dependence in patients aged 65 y and older with short bowel syndrome: a retrospective observational cohort study.
Draullette M, de Dreuille B, Sanchez M, et al.
The American journal of clinical nutrition 2025; (121(6)):1387-1394 doi:10.1016/j.ajcnut.2025.02.032.
PMID: 40074039 - 74
Serial Transverse Duodenal Enteroplasty in Adults With Ultra-Short Bowel Syndrome: A Case Series.
Ramírez-Arbeláez JA, Orjuela R, Ramirez A, et al.
Cureus 2025; (17(4)):e83145 doi:10.7759/cureus.83145.
PMID: 40438799 - 75
Central line-associated bloodstream infections and complications in adult home parenteral nutrition: Observations from a quality improvement initiative.
Fessler TA, Crandall MB, Schumacher SE, Martin DN
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 2025; (40(6)):1612-1628 doi:10.1002/ncp.11338.
PMID: 40583336 - 76
Cyclic infusion mitigates liver dysfunction associated with continuous total parenteral nutrition in a novel murine model.
Willis NB, Mims TS, Antunes K, et al.
American journal of physiology. Gastrointestinal and liver physiology 2025; (329(4)):G536-G545 doi:10.1152/ajpgi.00033.2025.
PMID: 40789651 - 77
Three-year experience with GLP-2 analog in intestinal rehabilitation for pediatric-onset short bowel syndrome.
Tazuke Y, Kimura T, Ueno T, et al.
Pediatric surgery international 2025; (41(1)):273 doi:10.1007/s00383-025-06154-z.
PMID: 40875041 - 78
Geriatric syndromes in intestinal failure: An accelerated aging phenomenon in middle adulthood patients?
Sandoval-Valdez DA, Reyes Ramírez ALDC, Serralde Zúñiga AE, Castillo Martínez L
Clinical nutrition ESPEN 2025; (70()):554-561 doi:10.1016/j.clnesp.2025.10.020.
PMID: 41167511 - 79
The medical benefits of fully integrated intestinal rehabilitation psychology: A case report.
McKillop HN, Flahive CB, Gniadek M, et al.
Intestinal Failure (New York, N.Y.) 2024; (3()):100037 doi:10.1016/j.intf.2025.100037.
PMID: 41647104 - 80
Patients' and their caregivers' experiences with home parenteral nutrition: a qualitative study using the Donabedian model.
Tamer F, Kapucu S, Halil MG
International journal for quality in health care : journal of the International Society for Quality in Health Care 2026; (38(1)) doi:10.1093/intqhc/mzag027.
PMID: 41739668