Research & Literature

Evaluation of Levothyroxine Bioavailability after Oral Administration of a Fixed Combination of Soy Isoflavones in Post-menopausal Female Volunteers.

Persiani S, Sala F, Manzotti C, et al.

Drug research 2016; (66(3)):136-40 doi:10.1055/s-0035-1555784.

Transient Congenital Hypothyroidism in Turkey: An Analysis on Frequency and Natural Course.

Kara C, Günindi F, Can Yılmaz G, Aydın M

Journal of clinical research in pediatric endocrinology 2016; (8(2)):170-9 doi:10.4274/jcrpe.2345.

Frequency of thyroid status monitoring in the first year of life and predictors for more frequent monitoring in infants with congenital hypothyroidism.

Zdraveska N, Anastasovska V, Kocova M

Journal of pediatric endocrinology & metabolism : JPEM 2016; (29(7)):795-800.

Etiological evaluation of primary congenital hypothyroidism cases.

Bezen D, Dilek E, Torun N, Tütüncüler F

Turk pediatri arsivi 2017; (52(2)):85-91 doi:10.5152/TurkPediatriArs.2017.3989.

Sustained attention in school-age children with congenital hypothyroidism: Influence of episodes of overtreatment in the first three years of life.

García Morales L, Rodríguez Arnao MD, Rodríguez Sánchez A, et al.

Neurologia 2020; (35(4)):226-232 doi:10.1016/j.nrl.2017.08.003.

Exploring predictors of change in behavioral problems over a 1-year period in preterm born preschoolers.

Schappin R, Wijnroks L, Uniken Venema M, Jongmans M

Infant behavior & development 2018; (50()):98-106 doi:10.1016/j.infbeh.2017.12.003.

Mean High-Dose l-Thyroxine Treatment Is Efficient and Safe to Achieve a Normal IQ in Young Adult Patients With Congenital Hypothyroidism.

Aleksander PE, Brückner-Spieler M, Stoehr AM, et al.

The Journal of clinical endocrinology and metabolism 2018; (103(4)):1459-1469 doi:10.1210/jc.2017-01937.

Newborn Screening Guidelines for Congenital Hypothyroidism in India: Recommendations of the Indian Society for Pediatric and Adolescent Endocrinology (ISPAE) - Part I: Screening and Confirmation of Diagnosis.

Desai MP, Sharma R, Riaz I, et al.

Indian journal of pediatrics 2018; (85(6)):440-447 doi:10.1007/s12098-017-2575-y.

Liquid L-thyroxine versus tablet L-thyroxine in patients on L- thyroxine replacement or suppressive therapy: a meta-analysis.

Laurent I, Tang S, Astère M, et al.

Endocrine 2018; (61(1)):28-35 doi:10.1007/s12020-018-1574-8.

Concurrent Milk Ingestion Decreases Absorption of Levothyroxine.

Chon DA, Reisman T, Weinreb JE, et al.

Thyroid : official journal of the American Thyroid Association 2018; (28(4)):454-457 doi:10.1089/thy.2017.0428.

The genetic characteristics of congenital hypothyroidism in China by comprehensive screening of 21 candidate genes.

Sun F, Zhang JX, Yang CY, et al.

European journal of endocrinology 2018; (178(6)):623-633.

Thyroid Hypoplasia in Congenital Hypothyroidism Associated with Thyroid Peroxidase Mutations.

Stoupa A, Chaabane R, Guériouz M, et al.

Thyroid : official journal of the American Thyroid Association 2018; (28(7)):941-944 doi:10.1089/thy.2017.0502.

Effect of Thyroid Hormones on Neurons and Neurodevelopment.

Prezioso G, Giannini C, Chiarelli F

Hormone research in paediatrics 2018; (90(2)):73-81 doi:10.1159/000492129.

L-thyroxine malabsorption due to calcium carbonate impairs blood pressure, total cholesterolemia, and fasting glycemia.

Morini E, Catalano A, Lasco A, et al.

Endocrine 2019; (64(2)):284-292 doi:10.1007/s12020-018-1798-7.

Newborn Screening and Molecular Profile of Congenital Hypothyroidism in a Chinese Population.

Yu B, Long W, Yang Y, et al.

Frontiers in genetics 2018; (9()):509 doi:10.3389/fgene.2018.00509.

Evaluation and management of the child with hypothyroidism.

Leung AKC, Leung AAC

World journal of pediatrics : WJP 2019; (15(2)):124-134 doi:10.1007/s12519-019-00230-w.

Vulnerable Child Syndrome.

Schmitz K

Pediatrics in review 2019; (40(6)):313-315 doi:10.1542/pir.2017-0243.

Levothyroxine Dose Adjustment to Optimise Therapy Throughout a Patient's Lifetime.

Duntas LH, Jonklaas J

Advances in therapy 2019; (36(Suppl 2)):30-46 doi:10.1007/s12325-019-01078-2.

Role of Maternal Thyroid-Stimulating Immunoglobulin in Graves' Disease for Predicting Perinatal Thyroid Dysfunction.

Cui Y, Rijhsinghani A

AJP reports 2019; (9(4)):e341-e345 doi:10.1055/s-0039-1694035.

Update on congenital hypothyroidism.

Cherella CE, Wassner AJ

Current opinion in endocrinology, diabetes, and obesity 2020; (27(1)):63-69 doi:10.1097/MED.0000000000000520.

Complicated Relationship between Genetic Mutations and Phenotypic Characteristics in Transient and Permanent Congenital Hypothyroidism: Analysis of Pooled Literature Data.

Long W, Zhou L, Wang Y, et al.

International journal of endocrinology 2020; (2020()):6808517 doi:10.1155/2020/6808517.

Impact of the reduction in TSH cutoff level to 6 mIU/L in neonatal screening for congenital hypothyroidism in Santa Catarina: final results.

Nascimento ML, Nascimento AL, Dornbusch P, et al.

Archives of endocrinology and metabolism 2021; (64(6)):816-823.

Thyroid imaging study in children with suspected thyroid dysgenesis.

Chun S, Lee YS, Yu J

Annals of pediatric endocrinology & metabolism 2021; (26(1)):53-59 doi:10.6065/apem.2040120.060.

ADHESION TO TREATMENT BY CHILDREN WITH CONGENITAL HYPOTHYROIDISM: KNOWLEDGE OF CAREGIVERS IN BAHIA STATE, BRAZIL.

Brito LNS, Andrade CLO, Alves CAD

Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo 2021; (39()):e2020074 doi:10.1590/1984-0462/2021/39/2020074.

Infants Diagnosed with Athyreosis on Scintigraphy May Have a Gland Present on Ultrasound and Have Transient Congenital Hypothyroidism.

McGrath N, Hawkes CP, Ryan S, et al.

Hormone research in paediatrics 2021; (94(1-2)):36-43 doi:10.1159/000514989.

[Social, cognitive and psychomotor development in peruvian children with congenital hypothyroidism].

Herrera-Chinchay L, Silva-Ocas I, Castro-Silva N, Del Águila Villar C

Andes pediatrica : revista Chilena de pediatria 2021; (92(2)):235-240 doi:10.32641/andespediatr.v92i2.1955.

Thyroid Function in Preterm/Low Birth Weight Infants: Impact on Diagnosis and Management of Thyroid Dysfunction.

LaFranchi SH

Frontiers in endocrinology 2021; (12()):666207 doi:10.3389/fendo.2021.666207.

The mutation screening in candidate genes related to thyroid dysgenesis by targeted next-generation sequencing panel in the Chinese congenital hypothyroidism.

Zhang RJ, Yang GL, Cheng F, et al.

Clinical endocrinology 2022; (96(4)):617-626 doi:10.1111/cen.14577.

Case Report: Expanding the Digenic Variants Involved in Thyroid Hormone Synthesis-10 New Cases of Congenital Hypothyroidism and a Literature Review.

Yang R, Lu Y, Yang C, et al.

Frontiers in genetics 2021; (12()):694683 doi:10.3389/fgene.2021.694683.

Non-inferiority of liquid thyroxine in comparison to tablets formulation in the treatment of children with congenital hypothyroidism.

Tzifi F, Iliadi A, Voutetakis A, et al.

Journal of pediatric endocrinology & metabolism : JPEM 2022; (35(2)):239-247 doi:10.1515/jpem-2021-0458.

Congenital Hypothyroidism.

Brady J, Cannupp A, Myers J, Jnah AJ

Neonatal network : NN 2021; (40(6)):377-385 doi:10.1891/11-T-699.

Prevalence of transient congenital hypothyroidism among neonates.

Alavi ER, Rafiei N, Rafiei R, Farokhi E

Annals of medicine and surgery (2012) 2021; (72()):103083 doi:10.1016/j.amsu.2021.103083.

Fifty years of newborn screening for congenital hypothyroidism: current status in Australasia and the case for harmonisation.

Huynh T, Greaves R, Mawad N, et al.

Clinical chemistry and laboratory medicine 2022; (60(10)):1551-1561 doi:10.1515/cclm-2022-0403.

Iatrogenic hyperthyroidism in primary congenital hypothyroidism: prevalence and predictive factors.

Chooprasertsuk N, Dejkhamron P, Unachak K, Wejaphikul K

Journal of pediatric endocrinology & metabolism : JPEM 2022; (35(10)):1250-1256 doi:10.1515/jpem-2022-0152.

Effect of initial levothyroxine dose on neurodevelopmental and growth outcomes in children with congenital hypothyroidism.

Esposito A, Vigone MC, Polizzi M, et al.

Frontiers in endocrinology 2022; (13()):923448 doi:10.3389/fendo.2022.923448.

Congenital Hypothyroidism: Screening and Management.

Rose SR, Wassner AJ, Wintergerst KA, et al.

Pediatrics 2023; (151(1)) doi:10.1542/peds.2022-060420.

Effects of a false-positive result in newborn congenital hypothyroidism screening on parents in Guangxi, China.

Tu SJ, Wei YJ, Chen BT, et al.

Frontiers in pediatrics 2023; (11()):1134923 doi:10.3389/fped.2023.1134923.

Medications and Food Interfering with the Bioavailability of Levothyroxine: A Systematic Review.

Liu H, Lu M, Hu J, et al.

Therapeutics and clinical risk management 2023; (19()):503-523 doi:10.2147/TCRM.S414460.

Worsening of Congenital Hypothyroidism After Start of Carob-bean Gum Thickened Formula: Is There a Link? A Case Report

Signorino C, Municchi G, Ferrari M, Stagi S

Journal of clinical research in pediatric endocrinology 2025; (17(2)):237-241 doi:10.4274/jcrpe.galenos.2023.2023-9-12.

Integrated Diagnostics of Thyroid Nodules.

Giovanella L, Campennì A, Tuncel M, Petranović Ovčariček P

Cancers 2024; (16(2)) doi:10.3390/cancers16020311.

The Value of Reducing Inconclusive and False-Positive Newborn Screening Results for Congenital Hypothyroidism, Congenital Adrenal Hyperplasia and Maple Syrup Urine Disease in The Netherlands.

Martens RC, Boelen A, van der Kemp MH, et al.

International journal of neonatal screening 2024; (10(4)) doi:10.3390/ijns10040070.

Growth Outcomes and Final Height in Children with Acquired Hypothyroidism: A Systematic Review.

Cammisa I, Rigante D, Cipolla C

Children (Basel, Switzerland) 2024; (11(12)) doi:10.3390/children11121510.

Clinical Insight into Congenital Hypothyroidism Among Children.

Korkmaz HA

Children (Basel, Switzerland) 2025; (12(1)) doi:10.3390/children12010055.

The Role of Neck Ultrasonography and Nuclear Imaging in the Diagnosis of Congenital Hypothyroidism.

Sumathy S, Palanivel S, Nagaraju K, et al.

Indian journal of endocrinology and metabolism 2024; (28(6)):611-616 doi:10.4103/ijem.ijem_7_24.

Variable transduction of thyroid hormone signaling in structures of the mouse brain.

Sinkó R, Salas-Lucia F, Mohácsik P, et al.

Proceedings of the National Academy of Sciences of the United States of America 2025; (122(6)):e2415970122 doi:10.1073/pnas.2415970122.

Transient Neonatal Hypothyroidism Followed by Hyperthyroidism Due to Maternal Thyrotropin Receptor Antibodies.

Garrelfs M, Kamp GA, van Trotsenburg ASP

JCEM case reports 2025; (3(3)):luaf040 doi:10.1210/jcemcr/luaf040.

Prevalence of Congenital Hypothyroidism and Efficacy of Current Cord Sample Screening in the Presence of Metabolic Screening: A Retrospective Cohort Study.

Alwadani IM, Almohammadi AM, Alzamzami WN

Cureus 2025; (17(2)):e79185 doi:10.7759/cureus.79185.

Term birth and levothyroxine dosage are significant factors associated with permanent congenital hypothyroidism: experience from a medical center in Taiwan.

Kao YE, Ting WH, Lee YJ, et al.

BMC pediatrics 2025; (25(1)):814 doi:10.1186/s12887-025-06199-y.

Prematurity Appears to Be the Main Factor for Transient Congenital Hypothyroidism in Greece, a Recently Iodine-Replete Country.

Koukkou EG, Girginoudis P, Nikolaou M, et al.

Nutrients 2025; (17(19)) doi:10.3390/nu17193039.

Evaluation of Transient or Permanent Congenital Hypothyroidism.

Kurtoğlu S, Baştuğ O, Özdemir A

Journal of clinical practice and research 2023; (45(4)):321-326 doi:10.14744/cpr.2023.32042.