Research & Literature

Mesial Temporal Lobe Epilepsy in Congenital Toxoplasmosis: A Case Report.

Jeong WK, Joo BE, Seo JH, et al.

Journal of epilepsy research 2015; (5(1)):25-8 doi:10.14581/jer.15007.

Patterns of Hydrocephalus Caused by Congenital Toxoplasma gondii Infection Associate With Parasite Genetics.

Hutson SL, Wheeler KM, McLone D, et al.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2015; (61(12)):1831-4 doi:10.1093/cid/civ720.

Congenital Toxoplasmosis: A Review.

Hampton MM

Neonatal network : NN 2015; (34(5)):274-8 doi:10.1891/0730-0832.34.5.274.

Prognosis of Fetal Parenchymal Cerebral Lesions without Ventriculomegaly in Congenital Toxoplasmosis Infection.

Dhombres F, Friszer S, Maurice P, et al.

Fetal diagnosis and therapy 2017; (41(1)):8-14 doi:10.1159/000445113.

Is Toxoplasma gondii type related to clinical outcome in human congenital infection? Systematic and critical review.

Rico-Torres CP, Vargas-Villavicencio JA, Correa D

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2016; (35(7)):1079-88 doi:10.1007/s10096-016-2656-2.

Frequency of anti- Toxoplasma gondii IgA, IgM, and IgG antibodies in high-risk pregnancies, in Brazil.

Murata FH, Ferreira MN, Camargo NS, et al.

Revista da Sociedade Brasileira de Medicina Tropical 2016; (49(4)):512-4.

Congenital toxoplasmosis: Clinical features, outcomes, treatment, and prevention.

Singh S

Tropical parasitology 2016; (6(2)):113-122 doi:10.4103/2229-5070.190813.

Late diagnosis of congenital toxoplasmosis based on serological follow-up: A case report.

Dard C, Chemla C, Fricker-Hidalgo H, et al.

Parasitology international 2017; (66(2)):186-189 doi:10.1016/j.parint.2016.12.004.

High Frequency of Bone Marrow Depression During Congenital Toxoplasmosis Therapy in a Cohort of Children Identified by Neonatal Screening in Minas Gerais, Brazil.

Carellos EVM, de Andrade JQ, Romanelli RMC, et al.

The Pediatric infectious disease journal 2017; (36(12)):1169-1176 doi:10.1097/INF.0000000000001561.

Management of suspected primary Toxoplasma gondii infection in pregnant women in Norway: twenty years of experience of amniocentesis in a low-prevalence population.

Findal G, Helbig A, Haugen G, et al.

BMC pregnancy and childbirth 2017; (17(1)):127 doi:10.1186/s12884-017-1300-1.

[Effect of antenatal spiramycin treatment on the frequency of retinochoroiditis due to congenital toxoplasmosis in a Colombian cohort].

Zuluaga LM, Hernández JC, Castaño CF, Donado JH

Biomedica : revista del Instituto Nacional de Salud 2017; (37(0)):86-91 doi:10.7705/biomedica.v37i2.2818.

IgG Avidity Test in Congenital Toxoplasmosis Diagnoses in Newborns.

Fonseca ZC, Rodrigues IMX, Melo NCE, et al.

Pathogens (Basel, Switzerland) 2017; (6(2)) doi:10.3390/pathogens6020026.

Adverse Event Profile of Pyrimethamine-Based Therapy in Toxoplasmosis: A Systematic Review.

Ben-Harari RR, Goodwin E, Casoy J

Drugs in R&D 2017; (17(4)):523-544 doi:10.1007/s40268-017-0206-8.

First report of Toxoplasma gondii sporulated oocysts and Giardia duodenalis in commercial green-lipped mussels (Perna canaliculus) in New Zealand.

Coupe A, Howe L, Burrows E, et al.

Parasitology research 2018; (117(5)):1453-1463 doi:10.1007/s00436-018-5832-8.

Perinatal Care of Infants with Congenital Birth Defects.

Sewell EK, Keene S

Clinics in perinatology 2018; (45(2)):213-230 doi:10.1016/j.clp.2018.01.007.

Hearing Disorders in Congenital Toxoplasmosis: A Literature Review.

Corrêa CC, Maximino LP, Weber SAT

International archives of otorhinolaryngology 2018; (22(3)):330-333 doi:10.1055/s-0037-1605377.

Congenital toxoplasmosis: An overview of the neurological and ocular manifestations.

Khan K, Khan W

Parasitology international 2018; (67(6)):715-721 doi:10.1016/j.parint.2018.07.004.

Adverse Reactions in Antifolate-Treated Toxoplasmic Retinochoroiditis.

Borkowski PK, Brydak-Godowska J, Basiak W, et al.

Advances in experimental medicine and biology 2018; (1108()):37-48 doi:10.1007/5584_2018_262.

Treatment of Toxoplasmosis: Historical Perspective, Animal Models, and Current Clinical Practice.

Dunay IR, Gajurel K, Dhakal R, et al.

Clinical microbiology reviews 2018; (31(4)) doi:10.1128/CMR.00057-17.

Role of Toxoplasma IgA as Part of a Reference Panel for the Diagnosis of Acute Toxoplasmosis during Pregnancy.

Olariu TR, Blackburn BG, Press C, et al.

Journal of clinical microbiology 2019; (57(2)) doi:10.1128/JCM.01357-18.

Maternal and Congenital Toxoplasmosis: Diagnosis and Treatment Recommendations of a French Multidisciplinary Working Group.

Peyron F, L'ollivier C, Mandelbrot L, et al.

Pathogens (Basel, Switzerland) 2019; (8(1)) doi:10.3390/pathogens8010024.

Is having any prenatal care associated with lower infant mortality in West Africa? Evidence from the Demographic and Health Surveys.

Taylor YJ, Laditka JN, Laditka SB, et al.

Health care for women international 2019; (40(2)):196-212 doi:10.1080/07399332.2018.1522317.

Outcomes of hydrocephalus secondary to congenital toxoplasmosis.

McLone D, Frim D, Penn R, et al.

Journal of neurosurgery. Pediatrics 2019; (24(5)):601-608 doi:10.3171/2019.6.PEDS18684.

Innate, adaptive, and cell-autonomous immunity against Toxoplasma gondii infection.

Sasai M, Yamamoto M

Experimental & molecular medicine 2019; (51(12)):1-10 doi:10.1038/s12276-019-0353-9.

Toxoplasma gondii tkl1 Deletion Mutant Is a Promising Vaccine against Acute, Chronic, and Congenital Toxoplasmosis in Mice.

Wang JL, Liang QL, Li TT, et al.

Journal of immunology (Baltimore, Md. : 1950) 2020; (204(6)):1562-1570 doi:10.4049/jimmunol.1900410.

A Proinflammatory Immune Response Might Determine Toxoplasma gondii Vertical Transmission and Severity of Clinical Features in Congenitally Infected Newborns.

Gómez-Chávez F, Cañedo-Solares I, Ortiz-Alegría LB, et al.

Frontiers in immunology 2020; (11()):390 doi:10.3389/fimmu.2020.00390.

Toxoplasma gondii-specific IgG avidity testing in pregnant women.

Garnaud C, Fricker-Hidalgo H, Evengård B, et al.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2020; (26(9)):1155-1160 doi:10.1016/j.cmi.2020.04.014.

Seronegative ocular toxoplasma panuveitis in an immunocompetent patient.

Sigle M, El Atrouni W, Ajlan RS

American journal of ophthalmology case reports 2020; (19()):100745 doi:10.1016/j.ajoc.2020.100745.

Treatment of Folate Metabolism Abnormalities in Autism Spectrum Disorder.

Frye RE, Rossignol DA, Scahill L, et al.

Seminars in pediatric neurology 2020; (35()):100835 doi:10.1016/j.spen.2020.100835.

Treatment of Acute Toxoplasmosis in Pregnancy: Influence in the Mother-to-Child Transmission.

Bartholo BBGR, Monteiro DLM, Rodrigues NCP, et al.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC 2020; (42(12)):1505-1510 doi:10.1016/j.jogc.2020.04.021.

A Comprehensive Subcellular Atlas of the Toxoplasma Proteome via hyperLOPIT Provides Spatial Context for Protein Functions.

Barylyuk K, Koreny L, Ke H, et al.

Cell host & microbe 2020; (28(5)):752-766.e9 doi:10.1016/j.chom.2020.09.011.

Ocular Outcome of Brazilian Patients With Congenital Toxoplasmosis.

Lago EG, Endres MM, Scheeren MFDC, Fiori HH

The Pediatric infectious disease journal 2021; (40(1)):e21-e27 doi:10.1097/INF.0000000000002931.

All about Toxoplasma gondii infections in pigs: 2009-2020.

Dubey JP, Cerqueira-Cézar CK, Murata FHA, et al.

Veterinary parasitology 2020; (288()):109185 doi:10.1016/j.vetpar.2020.109185.

[Toxoplasmosis in pregnancy: Practical Management].

Mandelbrot L, Kieffer F, Wallon M, et al.

Gynecologie, obstetrique, fertilite & senologie 2021; (49(10)):782-791 doi:10.1016/j.gofs.2021.03.003.

Ocular Findings in Infants with Congenital Toxoplasmosis after a Toxoplasmosis Outbreak.

Conceição AR, Belucik DN, Missio L, et al.

Ophthalmology 2021; (128(9)):1346-1355 doi:10.1016/j.ophtha.2021.03.009.

One severe case of congenital toxoplasmosis in China with good response to azithromycin.

Li J, Zhao J, Yang X, et al.

BMC infectious diseases 2021; (21(1)):920 doi:10.1186/s12879-021-06619-1.

A fresh look at the role of spiramycin in preventing a neglected disease: meta-analyses of observational studies.

Montoya JG, Laessig K, Fazeli MS, et al.

European journal of medical research 2021; (26(1)):143 doi:10.1186/s40001-021-00606-7.

Congenital Toxoplasmosis: The State of the Art.

Bollani L, Auriti C, Achille C, et al.

Frontiers in pediatrics 2022; (10()):894573 doi:10.3389/fped.2022.894573.

Anti-Toxoplasma Effects of Dracocephalum Polychaetum Essential Oil.

Khamesipour F, Pourmohammad A, Jafarian-Dehkordi M

Interdisciplinary perspectives on infectious diseases 2022; (2022()):6091834 doi:10.1155/2022/6091834.

Anti-Toxoplasma gondii IgM Long Persistence: What Are the Underlying Mechanisms?

Vargas-Villavicencio JA, Cañedo-Solares I, Correa D

Microorganisms 2022; (10(8)) doi:10.3390/microorganisms10081659.

[Ocular toxoplasmosis in infants 0 to 12 months of age with congenital toxoplasmosis].

González V L, Cardozo S O, Samudio A M, Mesquita R M

Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia 2022; (39(3)):265-272 doi:10.4067/s0716-10182022000200265.

Asymmetric eye size in an infant.

Edwards BD, Vayalumkal JV, Chawla R, et al.

Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada 2020; (5(3)):187-192 doi:10.3138/jammi-2020-0006.

Congenital toxoplasmosis with severe neurological disease in a referral hospital in Peru.

Maquera-Afaray J, Luna-Vilchez M, Salazar-Mesones B, et al.

Revista peruana de medicina experimental y salud publica 2022; (39(2)):208-213 doi:10.17843/rpmesp.2022.392.10897.

Toxoplasmosis Infection during Pregnancy.

Deganich M, Boudreaux C, Benmerzouga I

Tropical medicine and infectious disease 2022; (8(1)) doi:10.3390/tropicalmed8010003.

Toxoplasmosis: A Timeless Challenge for Pregnancy.

Damar Çakırca T, Can İN, Deniz M, et al.

Tropical medicine and infectious disease 2023; (8(1)) doi:10.3390/tropicalmed8010063.

Evaluation of the impact of the first evidence-based guidelines for congenital toxoplasmosis in Armenia (Quindío) Colombia: An observational retrospective analysis.

Mejia-Oquendo M, Marulanda-Ibarra E, Gomez-Marin JE

Lancet regional health. Americas 2021; (1()):100010 doi:10.1016/j.lana.2021.100010.

Evaluation of Toxoplasma gondii IgG avidity assays through a comparison of IgM serostatus.

Ikuta K, Kanno R, Bessho T, et al.

Diagnostic microbiology and infectious disease 2023; (105(4)):115901 doi:10.1016/j.diagmicrobio.2023.115901.

Risk factors for recurrences and visual impairment in patients with ocular toxoplasmosis: A systematic review and meta-analysis.

Cifuentes-González C, Rojas-Carabali W, Pérez ÁO, et al.

PloS one 2023; (18(4)):e0283845 doi:10.1371/journal.pone.0283845.

Comparison of adverse reactions of spiramycin versus pyrimethamine/sulfadiazine treatment of toxoplasmosis in pregnancy: is spiramycin really the drug of choice for unproven infection of the fetus?

Prasil P, Sleha R, Kacerovsky M, Bostik P

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2023; (36(1)):2215377 doi:10.1080/14767058.2023.2215377.

Prevalence of Toxoplasma gondii in Galapagos birds: Inference of risk factors associated with diet.

Mosquera JD, Valle CA, Nieto-Claudin A, et al.

PloS one 2023; (18(7)):e0287403 doi:10.1371/journal.pone.0287403.

Diagnosis of Congenital Toxoplasmosis: Challenges and Management Outcomes.

Losa A, Carvalho I, Sousa B, et al.

Cureus 2024; (16(1)):e52971 doi:10.7759/cureus.52971.

Employing digital PCR for enhanced detection of perinatal Toxoplasma gondii infection: A cross-sectional surveillance and maternal-infant outcomes study in El Salvador.

Lynn MK, Rodriguez Aquino MS, Cornejo Rivas PM, et al.

PLoS neglected tropical diseases 2024; (18(5)):e0012153 doi:10.1371/journal.pntd.0012153.

The prevention of congenital toxoplasmosis using a combination of Spiramycin and Cotrimoxazole: The long-time experience of a tertiary referral centre.

De Santis M, Tartaglia S, Apicella M, et al.

Tropical medicine & international health : TM & IH 2024; (29(8)):697-705 doi:10.1111/tmi.14021.

Navigating methotrexate toxicity: Examining the therapeutic roles of folinic acid and glucarpidase.

Chan BS, Bosco AA, Buckley NA

British journal of clinical pharmacology 2025; (91(3)):628-635 doi:10.1111/bcp.16096.

Mammalian placental explants: A tool for studying host-parasite interactions and placental biology.

Castillo C, Díaz-Luján C, Liempi A, et al.

Placenta 2025; (166()):62-70 doi:10.1016/j.placenta.2024.06.016.

Toxoplasma gondii genotypes and frequency in domestic cats from Romania.

Györke A, Balea A, Borșan S, et al.

BMC veterinary research 2024; (20(1)):369 doi:10.1186/s12917-024-04210-9.

Associations between Fetal Symptoms during Pregnancy and Neonatal Clinical Complications with Toxoplasmosis.

Tűzkő N, Bartek V, Simonyi A, et al.

Children (Basel, Switzerland) 2024; (11(9)) doi:10.3390/children11091111.

Microcephaly Resulting From Congenital Toxoplasmosis: What the Radiologist can Expect to See? A Case Report.

Salma M, Soumia EG, Ihssan HH, et al.

Radiology case reports 2024; (19(12)):6657-6661 doi:10.1016/j.radcr.2024.09.079.

Efficacy of amniotic fluid, blood and urine samples for the diagnosis of toxoplasmosis in pregnant women candidates for amniocentesis using serological and molecular techniques.

Abedian R, Esboei BR, Kordi S, et al.

BMC pregnancy and childbirth 2024; (24(1)):771 doi:10.1186/s12884-024-06979-x.

The effectiveness of congenital toxoplasmosis treatment in minimizing hearing loss: A systematic review.

Silva Santos RM, Liboredo R, da Silva AS, et al.

Science progress 2025; (108(2)):368504251320834 doi:10.1177/00368504251320834.

Congenital toxoplasmosis: an observational retrospective study in the Eastern Sicily.

Garozzo MT, Garozzo R, Betta P, et al.

Frontiers in pediatrics 2025; (13()):1597001 doi:10.3389/fped.2025.1597001.

Congenital toxoplasmosis.

Cerisola A, Francia M, Gesuele JP

Seminars in pediatric neurology 2025; (54()):101203 doi:10.1016/j.spen.2025.101203.

Function and mechanism of dopamine receptor D2 (DRD2) in neuroinflammation and behavioral disorders in C57BL/6J mice infected with Toxoplasma gondii TgCtWh6 strain.

Sun H, Xie X, Li Y, et al.

Brain, behavior, and immunity 2026; (131()):106136 doi:10.1016/j.bbi.2025.106136.

IgG avidity and placenta real-time PCR in detection of active maternal toxoplasmosis: relation to pregnancy outcomes.

Allam AF, Shehab AY, Ahmed NA, et al.

Experimental parasitology 2025; (279()):109065 doi:10.1016/j.exppara.2025.109065.