Research & Literature

Anxiety Measures Predict Health-Related Quality of Life in Children and Adolescents with Cyclic Vomiting Syndrome.

Tarbell SE, Li BU

The Journal of pediatrics 2015; (167(3)):633-8.e1.

Cyclic vomiting syndrome versus inborn errors of metabolism: A review with clinical recommendations.

Gelfand AA, Gallagher RC

Headache 2016; (56(1)):215-21 doi:10.1111/head.12749.

Cyclic Vomiting Syndrome: A Functional Disorder.

Kaul A, Kaul KK

Pediatric gastroenterology, hepatology & nutrition 2015; (18(4)):224-9 doi:10.5223/pghn.2015.18.4.224.

Cyclic Vomiting Syndrome in Infants and Children: A Clinical Follow-Up Study.

Hikita T, Kodama H, Ogita K, et al.

Pediatric neurology 2016; (57()):29-33.

Effect of Ondansetron on QT Interval in Patients Cared for in the PICU.

Trivedi S, Schiltz B, Kanipakam R, et al.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2016; (17(7)):e317-23 doi:10.1097/PCC.0000000000000776.

Cyclic Vomiting Syndrome is characterized by altered functional brain connectivity of the insular cortex: A cross-comparison with migraine and healthy adults.

Ellingsen DM, Garcia RG, Lee J, et al.

Neurogastroenterology and motility 2017; (29(6)) doi:10.1111/nmo.13004.

Cannabinoid hyperemesis and the cyclic vomiting syndrome in adults: recognition, diagnosis, acute and long-term treatment.

Blumentrath CG, Dohrmann B, Ewald N

German medical science : GMS e-journal 2017; (15()):Doc06 doi:10.3205/000247.

Cyclic Vomiting Syndrome in Adults and Children: A Hypothesis.

Redon S, Mareau C, Guedj E, Donnet A

Headache 2017; (57(6)):943-951 doi:10.1111/head.13108.

Cannabinoid hyperemesis syndrome: A disorder of the HPA axis and sympathetic nervous system?

Richards JR

Medical hypotheses 2017; (103()):90-95 doi:10.1016/j.mehy.2017.04.018.

Depression, young age, chronic marijuana use, and interepisodic symptoms predict psychological distress in patients with cyclic vomiting syndrome.

Taranukha T, Charan Suresh Kumar V, Seamon A, et al.

Neurogastroenterology and motility 2018; (30(4)):e13245 doi:10.1111/nmo.13245.

Yield and Costs of Evaluating Children With Cyclic Vomiting Syndrome.

Lucia-Casadonte CJ, Whaley KG, Chogle AS

Journal of pediatric gastroenterology and nutrition 2018; (67(1)):13-17 doi:10.1097/MPG.0000000000001901.

Cyclic vomiting syndrome: diagnostic approach and current management strategies.

Hayes WJ, VanGilder D, Berendse J, et al.

Clinical and experimental gastroenterology 2018; (11()):77-84 doi:10.2147/CEG.S136420.

Chronic nausea and vomiting: evaluation and treatment.

Lacy BE, Parkman HP, Camilleri M

The American journal of gastroenterology 2018; (113(5)):647-659 doi:10.1038/s41395-018-0039-2.

Cyclic Vomiting Syndrome in Children.

Donnet A, Redon S

Current pain and headache reports 2018; (22(4)):30 doi:10.1007/s11916-018-0684-6.

Family Health-related Quality of Life in Pediatric Cyclic Vomiting Syndrome.

Wang-Hall J, Li BUK, Tarbell SE

Journal of pediatric gastroenterology and nutrition 2018; (66(5)):738-743 doi:10.1097/MPG.0000000000001797.

Epidemiology, Clinical Characteristics, and Associations for Rome IV Functional Nausea and Vomiting Disorders in Adults.

Aziz I, Palsson OS, Whitehead WE, et al.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2019; (17(5)):878-886 doi:10.1016/j.cgh.2018.05.020.

Managing cyclic vomiting syndrome in children: beyond the guidelines.

Li BUK

European journal of pediatrics 2018; (177(10)):1435-1442 doi:10.1007/s00431-018-3218-7.

Cyclic Vomiting Syndrome.

Aiman S, Kundal B, Chopra G

Saudi journal of medicine & medical sciences 2016; (4(1)):45-46 doi:10.4103/1658-631X.170895.

Cyclic vomiting syndrome and benign paroxysmal torticollis are associated with a high risk of developing primary headache: A longitudinal study.

Moavero R, Papetti L, Bernucci MC, et al.

Cephalalgia : an international journal of headache 2019; (39(10)):1236-1240 doi:10.1177/0333102419844542.

Management of cyclic vomiting syndrome in adults: Evidence review.

Sharaf RN, Venkatesan T, Shah R, et al.

Neurogastroenterology and motility 2019; (31 Suppl 2()):e13605 doi:10.1111/nmo.13605.

Guidelines on management of cyclic vomiting syndrome in adults by the American Neurogastroenterology and Motility Society and the Cyclic Vomiting Syndrome Association.

Venkatesan T, Levinthal DJ, Tarbell SE, et al.

Neurogastroenterology and motility 2019; (31 Suppl 2()):e13604 doi:10.1111/nmo.13604.

Patterns of Cannabis Use in Patients With Cyclic Vomiting Syndrome.

Venkatesan T, Hillard CJ, Rein L, et al.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2020; (18(5)):1082-1090.e2 doi:10.1016/j.cgh.2019.07.039.

Acute Management of Pediatric Cyclic Vomiting Syndrome: A Systematic Review.

Gui S, Patel N, Issenman R, Kam AJ

The Journal of pediatrics 2019; (214()):158-164.e4 doi:10.1016/j.jpeds.2019.06.057.

Catamenial cyclic vomiting syndrome responding to oestrogen therapy: an adolescent case report.

Hassani MEME, Saad B, Mounir M, et al.

The Pan African medical journal 2019; (33()):286 doi:10.11604/pamj.2019.33.286.17978.

Highlighting the importance of early diagnosis of cyclic vomiting syndrome in adults: A case report.

Tang C, Dai N

Medicine 2019; (98(51)):e18365 doi:10.1097/MD.0000000000018365.

Neurological Etiologies and Pathophysiology of Cyclic Vomiting Syndrome.

McAbee GN, Morse AM, Cook W, et al.

Pediatric neurology 2020; (106()):4-9 doi:10.1016/j.pediatrneurol.2019.12.001.

Assessment of Gastric Emptying Times Between Pediatrics and Adults With Cyclic Vomiting Syndrome.

Kamal A, Sarvepalli S, Selvakumar P, et al.

Journal of clinical gastroenterology 2020; (54(9)):e89-e92 doi:10.1097/MCG.0000000000001352.

Predictors of Hospital Admission for Pediatric Cyclic Vomiting Syndrome.

Abdulkader ZM, Bali N, Vaz K, et al.

The Journal of pediatrics 2021; (232()):154-158 doi:10.1016/j.jpeds.2020.11.055.

Cyclic vomiting syndrome: A narrative review and guide to management.

Kovacic K, Li BUK

Headache 2021; (61(2)):231-243 doi:10.1111/head.14073.

Highly effective use of aprepitant in an adolescent girl with severe cyclic vomiting syndrome.

Nivatsi M, Aslanidou I, Mantadakis E

BMJ case reports 2021; (14(3)) doi:10.1136/bcr-2020-241132.

Clinical features and long-term outcomes in pediatric cyclic vomiting syndrome: A 9-year experience at three tertiary academic centers.

Dipasquale V, Falsaperla R, Bongiovanni A, et al.

Neurogastroenterology and motility 2022; (34(3)):e14224 doi:10.1111/nmo.14224.

Atypical idiopathic intracranial hypertension presenting as cyclic vomiting syndrome: a case report.

Talukder NT, Clorfeine AH, Black MK, Moody SB

Journal of medical case reports 2021; (15(1)):440 doi:10.1186/s13256-021-03068-x.

Death of a young woman with cyclic vomiting: a case report.

von Both I, Santos B

Forensic science, medicine, and pathology 2021; (17(4)):715-722 doi:10.1007/s12024-021-00410-z.

Development and Assessment of a Low Literacy, Pictographic Cyclic Vomiting Syndrome Action Plan.

Reeves PT, Kovacic K, Rogers PL, et al.

The Journal of pediatrics 2022; (242()):174-183.e1 doi:10.1016/j.jpeds.2021.10.047.

Cyclic vomiting syndrome in children.

Goldman RD

Canadian family physician Medecin de famille canadien 2021; (67(11)):837-838 doi:10.46747/cfp.6711837.

Cyclic Vomiting Syndrome in Pediatric Patients: A Review of Therapeutics.

Tillman EM, Harvath EM

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG 2022; (27(1)):12-18 doi:10.5863/1551-6776-27.1.12.

[Clinical and gastroscopic features of children with cyclic vomiting syndrome: an analysis of 63 cases].

Song L, Li YJ, Wang J, et al.

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 2022; (24(12)):1340-1344 doi:10.7499/j.issn.1008-8830.2206007.

Cardiac Vagal Regulation Is Impeded in Children With Cyclic Vomiting Syndrome.

Kolacz J, Kovacic K, Dang L, et al.

The American journal of gastroenterology 2023; (118(7)):1268-1275 doi:10.14309/ajg.0000000000002207.

Cyclic Vomiting Syndrome: An underdiagnosed entity. Report of a case.

Rodríguez F, Moratorio I, López V, Olano C

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru 2022; (42(4)):257-260.

Diagnosis and Management of Cyclic Vomiting Syndrome: A Critical Review.

Frazier R, Li BUK, Venkatesan T

The American journal of gastroenterology 2023; (118(7)):1157-1167 doi:10.14309/ajg.0000000000002216.

Cyclic vomiting syndrome, a common language? A 20-year bibliometric study.

Redon S, Donnet A

Acta neurologica Belgica 2023; (123(4)):1241-1245 doi:10.1007/s13760-023-02223-z.

Clinical characteristics and long-term outcomes in patients with cyclic vomiting syndrome: A 15-year experience at a tertiary referral center.

Partovi O, Patel M, Kovacic K, et al.

Neurogastroenterology and motility 2023; (35(7)):e14571 doi:10.1111/nmo.14571.

QT prolongation, torsades des pointes, and cardiac arrest after 4 mg of IV ondansetron.

Orozco BS, Lee SC, Fuchs RT, et al.

The American journal of emergency medicine 2023; (68()):214.e3-214.e6 doi:10.1016/j.ajem.2023.04.003.

Whole exome/genome sequencing in cyclic vomiting syndrome reveals multiple candidate genes, suggesting a model of elevated intracellular cations and mitochondrial dysfunction.

Bar O, Ebenau L, Weiner K, et al.

Frontiers in neurology 2023; (14()):1151835 doi:10.3389/fneur.2023.1151835.

Abdominal migraine and cyclical vomiting syndrome.

Cheema S, Matharu M

Handbook of clinical neurology 2023; (198()):209-219 doi:10.1016/B978-0-12-823356-6.00006-8.

Epidemiology, Comorbidities, and Treatment of Cyclic Vomiting Syndrome in the United States.

Chen YJ, Princic N, Winer I, et al.

The American journal of gastroenterology 2024; (119(5)):965-976 doi:10.14309/ajg.0000000000002628.

Navigating the Diagnostic Journey in Pediatric Gastroenterology: Decoding Recurrent Vomiting and Epigastric Pain in a Child with Glutaric Aciduria Type II.

Kek HP, Tsai WL, Chiu PC, et al.

Children (Basel, Switzerland) 2024; (11(3)) doi:10.3390/children11030285.

Single intravenous dose ondansetron induces QT prolongation in adult emergency department patients: a prospective observational study.

Rezaei Zadeh Rukerd M, Shahrbabaki FR, Movahedi M, et al.

International journal of emergency medicine 2024; (17(1)):49 doi:10.1186/s12245-024-00621-5.

AGA Clinical Practice Update on Diagnosis and Management of Cyclic Vomiting Syndrome: Commentary.

Levinthal DJ, Staller K, Venkatesan T

Gastroenterology 2024; (167(4)):804-811.e1 doi:10.1053/j.gastro.2024.05.031.

Evidence-based review and frontiers of migraine therapy.

Greene KA, Gelfand AA, Larry Charleston

Neurogastroenterology and motility 2025; (37(3)):e14899 doi:10.1111/nmo.14899.

Acute care of cyclic vomiting syndrome and cannabinoid hyperemesis syndrome in the home and emergency department.

Levinthal DJ, Killian B, Issenman RM

Neurogastroenterology and motility 2025; (37(3)):e14901 doi:10.1111/nmo.14901.

Cannabis use patterns and association with hyperemesis: A comprehensive review.

Hasler WL, Alshaarawy O, Venkatesan T

Neurogastroenterology and motility 2025; (37(3)):e14895 doi:10.1111/nmo.14895.

Worldwide Prevalence and Description of Cyclic Vomiting Syndrome According to the Results of the Rome Foundation Global Epidemiology Study.

Izagirre A, Sarasqueta C, Flores-Arriaga J, et al.

The American journal of gastroenterology 2025; (120(5)):1108-1115 doi:10.14309/ajg.0000000000003105.

Altered parasympathetic outflow and central sensitization response to continuous pain in cyclic vomiting syndrome: a functional magnetic resonance imaging study.

Bolender A, Staley R, Garcia RG, et al.

American journal of physiology. Gastrointestinal and liver physiology 2025; (328(2)):G125-G135 doi:10.1152/ajpgi.00011.2024.

Symptom Patterns in Adults With Cyclic Vomiting Syndrome: A 6-Month Prospective Observational Study.

Chen YJ, Rodriguez D, Richmond CA, et al.

Neurogastroenterology and motility 2025; (37(2)):e14974 doi:10.1111/nmo.14974.

Diagnostic characteristics of pediatric cyclic vomiting syndrome.

Bujarska M, Bora G, Li BUK, et al.

Journal of pediatric gastroenterology and nutrition 2025; (80(3)):417-425 doi:10.1002/jpn3.12448.

Understanding the adult and adolescent patient experience with cyclic vomiting syndrome: a concept elicitation study.

Karrento K, Wu M, Rodriguez D, et al.

BMC gastroenterology 2025; (25(1)):85 doi:10.1186/s12876-025-03595-7.

North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition 2025 guidelines for management of cyclic vomiting syndrome in children.

Karrento K, Rosen JM, Tarbell SE, et al.

Journal of pediatric gastroenterology and nutrition 2025; (80(6)):1028-1061 doi:10.1002/jpn3.70020.

Cyclic Vomiting Syndrome as a Migraine Variant in Adults: A Case Report.

Borei K, Nakawah MO

Pain medicine case reports 2024; (8(6)):213-215.

[The cannabinoid hyperemesis syndrome-A narrative review].

Bonnet U

Der Nervenarzt 2026; (97(4)):377-381 doi:10.1007/s00115-025-01864-0.

Cyclic Vomiting Syndrome and Cannabinoid Hyperemesis Syndrome: Their Intersection and Joint Existence.

Yacob D

Gastroenterology clinics of North America 2025; (54(3)):557-568 doi:10.1016/j.gtc.2025.05.004.

North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition 2025 guidelines on the diagnosis of cyclic vomiting syndrome in children.

Karrento K, Rosen JM, Gelfand AA, et al.

Journal of pediatric gastroenterology and nutrition 2025; (81(5)):1346-1359 doi:10.1002/jpn3.70193.

Morbidity and Mortality of Ondansetron in Patients with Non-congenital Long QT Syndrome: A Review Article.

Al-Ramadan A, Kidess GG, Bahar AR, et al.

Cardiovascular drugs and therapy 2026; (40(3)):1117-1124 doi:10.1007/s10557-025-07766-2.

[Cannabinoid Hyperemesis Syndrome: A Scoping Review].

Bonnet U

Fortschritte der Neurologie-Psychiatrie 2025; doi:10.1055/a-2704-5465.

Etiologies of Cyclic Vomiting Syndrome in Children: A Systematic Review of 1,373 Patients.

Waisfeld A, Randazzo I, Aronoff S, et al.

Pediatric gastroenterology, hepatology & nutrition 2026; (29(1)):62-70 doi:10.5223/pghn.2026.29.1.62.

Gastroduodenal Disorders.

Törnblom H, Carbone F, Hasler WL, et al.

Gastroenterology 2026; (170(6)):1240-1260 doi:10.1053/j.gastro.2026.01.038.

Effect of ondansetron on QTc interval prolongation in healthy pediatric patients: a systematic review and meta-analysis.

Carneiro IMC, Castelo Branco PES, Franco AHS, et al.

Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo 2026; (44()):e2025134 doi:10.1590/1984-0462/2026/44/2025134.

Avoidant-Restrictive Food Intake Disorder Is Common in Adults With Cyclic Vomiting Syndrome and Is Associated With Malnutrition.

Venkatesan T, Goday PS, Arumugam S, et al.

Neurogastroenterology and motility 2026; (38(4)):e70294 doi:10.1111/nmo.70294.

Clinical features, response to therapy and outcome in pediatric cyclical vomiting syndrome: Experience from the developing world.

Ananthashayana R, Srivastava A, Aravind A, et al.

Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 2026; doi:10.1007/s12664-026-01998-2.