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Gynecology · Ovarian Cystadenofibroma

Symptoms and Complications: When to Seek Care

At a Glance

Cystadenofibromas are benign ovarian tumors that often cause no symptoms, but larger masses can cause pelvic pain, bloating, urinary or bowel pressure. Sudden severe pain with nausea or vomiting may signal ovarian torsion, a surgical emergency.

Because cystadenofibromas are benign and grow slowly, they often do not cause any symptoms [1]. In many cases, these tumors are discovered “incidentally”—meaning they are found by chance during a routine pelvic exam or an imaging test for an unrelated issue [1]. However, depending on the size and location of the tumor, it can cause physical discomfort or medical complications.

Common Symptoms

When symptoms do occur, they are typically related to the size of the tumor or its mass effect in the pelvis [2][3]. You may experience:

  • Pelvic or Abdominal Pain: This can range from a dull, persistent heaviness in the lower abdomen to sharp, localized discomfort [4][5].
  • Bloating and Distension: Large tumors can cause a visible swelling of the abdomen that may be mistaken for weight gain [6][7].
  • Menstrual Changes: Some patients report changes in their cycle, though these symptoms are nonspecific and can have many other causes [1].

(Note: While some patients with ovarian masses experience difficulty becoming pregnant, a benign cystadenofibroma itself is not a proven direct cause of infertility. However, the physical presence of a very large mass or the surgery required to remove it can sometimes affect ovarian reserve.)

The “Mass Effect” on Nearby Organs

As a cystadenofibroma increases in size, it takes up significant space in the pelvis. Because the pelvis is crowded, a large tumor can press against surrounding organs [8]:

  • Bladder: Pressure on the bladder may cause you to feel like you need to urinate more frequently or urgently.
  • Bowel: If the tumor presses against the colon or rectum, it can lead to constipation or a feeling of incomplete bowel movements [8].
  • Diaphragm: In rare cases of giant tumors, the mass can push upward, making it feel difficult to take a full, deep breath [9].

Ovarian Torsion: A Medical Emergency

The most serious complication associated with any ovarian mass is ovarian torsion. This occurs when the weight or mobility of the tumor causes the ovary (and sometimes the fallopian tube) to twist on its “stalk,” cutting off its own blood supply [4][10].

The risk of torsion generally depends on the size and mobility of the mass, as well as your individual anatomy. (Some small retrospective studies have suggested that mixed-subtype tumors might grow larger and torsion more often, while serous tumors may be smaller and more frequently bilateral, but these are not strict rules for every patient [1]).

Warning Signs of Torsion

If the ovary twists, the blood supply is choked off, which can lead to permanent damage to the ovary if not treated immediately. Seek emergency medical care if you experience:

  • Sudden, Severe Pain: Sharp, agonizing pain in the lower abdomen or pelvis that often starts abruptly [11][12].
  • Nausea and Vomiting: These often accompany the intense pain of torsion [11].
  • Pain that Comes and Goes: Sometimes an ovary “twists and untwists” (intermittent torsion), causing bouts of severe pain that seem to resolve before returning later [13][14].

Do not wait for the pain to become unbearable. Torsion is a surgical emergency, and quick intervention is the best way to save the affected ovary [15][16].

Common questions in this guide

What symptoms can an ovarian cystadenofibroma cause?
Many ovarian cystadenofibromas cause no symptoms and are found during a routine exam or imaging for another reason. When a tumor is large, it may cause pelvic or abdominal pain, bloating, menstrual changes, or pressure on the bladder or bowel. These symptoms are not specific, so other causes may also need evaluation.
Can an ovarian cystadenofibroma cause frequent urination or constipation?
Yes. A larger mass can press on the bladder, causing frequent or urgent urination, or on the colon or rectum, causing constipation or a feeling of incomplete bowel movements.
What are the emergency warning signs of ovarian torsion?
Sudden, severe lower abdominal or pelvic pain, especially with nausea or vomiting, can be a warning sign. Pain may sometimes come and go if the ovary twists and untwists. Ovarian torsion is a surgical emergency, so seek emergency medical care promptly rather than waiting for the pain to become unbearable.
Does an ovarian cystadenofibroma increase the risk of ovarian torsion?
The risk of torsion is influenced by the mass's size and mobility, as well as individual anatomy. Ask your clinician how the tumor's size, movement, and imaging findings affect your personal risk.
Can an ovarian cystadenofibroma affect fertility or ovarian reserve?
A benign cystadenofibroma itself is not proven to directly cause infertility. However, a very large mass or surgery to remove it can sometimes affect ovarian reserve, so discuss fertility goals with your healthcare team.

Get notified when new evidence is published on cystadenofibroma.

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References

References (16)
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This page is for informational purposes and does not constitute medical advice. Sudden severe pelvic or abdominal pain, especially with nausea or vomiting, requires immediate evaluation for possible ovarian torsion.