Research & Literature

Clinical Utility of Viral Load in the Management of Cytomegalovirus Infection in Solid Organ Transplant Patients in Kuwait.

Madi N, Al-Qaser M, Edan R, Al-Nakib W

Transplantation proceedings 2015; (47(6)):1802-7.

Retrospective study of cytomegalovirus retinitis complicated with acquired immunodeficiency syndrome.

Huang G, Jiang Q, Li M, et al.

International journal of clinical and experimental medicine 2015; (8(6)):9537-42.

Routine Eye Screening by an Ophthalmologist Is Clinically Useful for HIV-1-Infected Patients with CD4 Count Less than 200 /μL.

Nishijima T, Yashiro S, Teruya K, et al.

PloS one 2015; (10(9)):e0136747 doi:10.1371/journal.pone.0136747.

Diagnosis and antenatal management of congenital cytomegalovirus infection.

, Hughes BL, Gyamfi-Bannerman C

American journal of obstetrics and gynecology 2016; (214(6)):B5-B11.

Sensitivity of blood and tissue diagnostics for gastrointestinal cytomegalovirus disease in solid organ transplant recipients.

Fisher CE, Alexander J, Bhattacharya R, et al.

Transplant infectious disease : an official journal of the Transplantation Society 2016; (18(3)):372-80 doi:10.1111/tid.12531.

A case report of small bowel perforation secondary to cytomegalovirus related immune reconstitution inflammatory syndrome in an AIDS patient.

Gutiérrez-Delgado EM, Villanueva-Lozano H, García Rojas-Acosta MJ, et al.

Annals of medicine and surgery (2012) 2017; (13()):20-23 doi:10.1016/j.amsu.2016.11.001.

Cytomegalovirus, Macrophages and Breast Cancer.

Pasquereau S, Al Moussawi F, Karam W, et al.

The open virology journal 2017; (11()):15-27 doi:10.2174/1874357901711010015.

Amniocentesis for prenatal diagnosis of cytomegalovirus infection: challenging the 21 weeks' threshold.

Enders M, Daiminger A, Exler S, Enders G

Prenatal diagnosis 2017; (37(9)):940-942 doi:10.1002/pd.5107.

Long-term impairment attributable to congenital cytomegalovirus infection: a retrospective cohort study.

Korndewal MJ, Oudesluys-Murphy AM, Kroes ACM, et al.

Developmental medicine and child neurology 2017; (59(12)):1261-1268 doi:10.1111/dmcn.13556.

Insight Into Long-term Neurodevelopmental Outcomes in Asymptomatic Congenital CMV Infection.

Boppana SB, Fowler KB

Pediatrics 2017; (140(5)) doi:10.1542/peds.2017-2526.

Impact of electronic health record-based, pharmacist-driven valganciclovir dose optimization in solid organ transplant recipients.

Hensler D, Richardson CL, Brown J, et al.

Transplant infectious disease : an official journal of the Transplantation Society 2018; (20(2)):e12849 doi:10.1111/tid.12849.

Immune Monitoring for CMV in Transplantation.

Yong MK, Lewin SR, Manuel O

Current infectious disease reports 2018; (20(4)):4 doi:10.1007/s11908-018-0610-4.

Hematologic Adverse Events Associated With Prolonged Valganciclovir Treatment in Congenital Cytomegalovirus Infection.

Ziv L, Yacobovich J, Pardo J, et al.

The Pediatric infectious disease journal 2019; (38(2)):127-130 doi:10.1097/INF.0000000000002079.

Pharmacologic and immunologic management of cytomegalovirus infection after solid organ and hematopoietic stem cell transplantation.

Meesing A, Razonable RR

Expert review of clinical pharmacology 2018; (11(8)):773-788 doi:10.1080/17512433.2018.1501557.

Usefulness of a flow chart for targeted screening of congenital cytomegalovirus-related hearing loss.

Ciccia M, Monari C, Vitagliano G, et al.

Journal of neonatal-perinatal medicine 2018; (11(3)):339-343 doi:10.3233/NPM-17110.

Active cytomegalovirus retinitis after the start of antiretroviral therapy.

Heiden D, Tun N, Smithuis FN, et al.

The British journal of ophthalmology 2019; (103(2)):157-160 doi:10.1136/bjophthalmol-2018-312406.

EBV VCA IgM and cytomegalovirus IgM dual positivity is a false positive finding related to age and hepatic involvement of primary Epstein-Barr virus infection in children.

Sohn MJ, Cho JM, Moon JS, et al.

Medicine 2018; (97(38)):e12380 doi:10.1097/MD.0000000000012380.

Potential Biomarkers for Predicting Congenital Cytomegalovirus Infection.

Tanimura K, Yamada H

International journal of molecular sciences 2018; (19(12)) doi:10.3390/ijms19123760.

Sequelae of Congenital Cytomegalovirus Following Maternal Primary Infections Are Limited to Those Acquired in the First Trimester of Pregnancy.

Faure-Bardon V, Magny JF, Parodi M, et al.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019; (69(9)):1526-1532 doi:10.1093/cid/ciy1128.

Drug Repurposing Campaigns for Human Cytomegalovirus Identify a Natural Compound Targeting the Immediate-Early 2 (IE2) Protein: A Comment on "The Natural Flavonoid Compound Deguelin Inhibits HCMV Lytic Replication within Fibroblasts".

Mercorelli B, Luganini A, Palù G, et al.

Viruses 2019; (11(2)) doi:10.3390/v11020117.

Routine Immediate Eye Examination at the Point of Care for Diagnosis of AIDS-Related Cytomegalovirus Retinitis Among Patients With a CD4 Count <100 in Myanmar.

Ei WLSS, Pyar Soe K, Hilbig A, et al.

Open forum infectious diseases 2019; (6(7)):ofz280 doi:10.1093/ofid/ofz280.

Assessment and prevention of cytomegalovirus infection in allogeneic hematopoietic stem cell transplant and in solid organ transplant: A multidisciplinary consensus conference by the Italian GITMO, SITO, and AMCLI societies.

Girmenia C, Lazzarotto T, Bonifazi F, et al.

Clinical transplantation 2019; (33(10)):e13666 doi:10.1111/ctr.13666.

Cytomegalovirus Retinitis Screening and Treatment in Human Immunodeficiency Virus Patients in Malawi: A Feasibility Study.

Ocieczek P, Barnacle JR, Gumulira J, et al.

Open forum infectious diseases 2019; (6(11)):ofz439 doi:10.1093/ofid/ofz439.

Treatment of congenital cytomegalovirus beyond the neonatal period: an observational study.

Dorfman L, Amir J, Attias J, Bilavsky E

European journal of pediatrics 2020; (179(5)):807-812 doi:10.1007/s00431-019-03558-7.

Impact of valganciclovir prophylaxis duration on cytomegalovirus disease in high-risk donor seropositive/recipient seronegative heart transplant recipients.

Imlay H, Dumitriu Carcoana AO, Fisher CE, et al.

Transplant infectious disease : an official journal of the Transplantation Society 2020; (22(3)):e13255 doi:10.1111/tid.13255.

[Neurological sequelae in patients with congenital cytomegalovirus].

de Juan Gallach A, Alemany Albert M, Marco Hernández AV, et al.

Anales de pediatria 2020; (93(2)):111-117 doi:10.1016/j.anpedi.2019.12.021.

Outcome and management of newborns with congenital cytomegalovirus infection.

Nicloux M, Peterman L, Parodi M, Magny JF

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 2020; (27(3)):160-165 doi:10.1016/j.arcped.2020.01.006.

Effect of Preemptive Therapy vs Antiviral Prophylaxis on Cytomegalovirus Disease in Seronegative Liver Transplant Recipients With Seropositive Donors: A Randomized Clinical Trial.

Singh N, Winston DJ, Razonable RR, et al.

JAMA 2020; (323(14)):1378-1387 doi:10.1001/jama.2020.3138.

Pathophysiology of Hyperechogenic Bowel in Congenitally Human Cytomegalovirus Infected Fetuses.

Gabrielli L, Bonasoni MP, Chiereghin A, et al.

Microorganisms 2020; (8(5)) doi:10.3390/microorganisms8050779.

Positive predictive values of CMV-IgM and importance of CMV-IgG avidity testing in detecting primary infection in three different clinical settings. A French retrospective cohort study.

Périllaud-Dubois C, Bouthry E, Jadoui A, et al.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2020; (132()):104641 doi:10.1016/j.jcv.2020.104641.

Epidemiology, risk factors, and outcomes associated with cytomegalovirus in adult kidney transplant recipients: A systematic literature review of real-world evidence.

Raval AD, Kistler KD, Tang Y, et al.

Transplant infectious disease : an official journal of the Transplantation Society 2021; (23(2)):e13483 doi:10.1111/tid.13483.

Congenital Cytomegalovirus Infection: Update on Diagnosis and Treatment.

Chiopris G, Veronese P, Cusenza F, et al.

Microorganisms 2020; (8(10)) doi:10.3390/microorganisms8101516.

Maternal cytomegalovirus immune status and hearing loss outcomes in congenital cytomegalovirus-infected offspring.

Demmler-Harrison GJ, Miller JA,

PloS one 2020; (15(10)):e0240172 doi:10.1371/journal.pone.0240172.

Regulation of the MIE Locus During HCMV Latency and Reactivation.

Dooley AL, O'Connor CM

Pathogens (Basel, Switzerland) 2020; (9(11)) doi:10.3390/pathogens9110869.

Cytomegalovirus infection in pregnancy - An update.

Navti OB, Al-Belushi M, Konje JC,

European journal of obstetrics, gynecology, and reproductive biology 2021; (258()):216-222 doi:10.1016/j.ejogrb.2020.12.006.

Epidemiology of cytomegalovirus Infection among mothers and infants in Colombia.

Rico A, Dollard SC, Valencia D, et al.

Journal of medical virology 2021; (93(11)):6393-6397 doi:10.1002/jmv.26815.

Sensitivity of Dried Blood Spot Testing for Detection of Congenital Cytomegalovirus Infection.

Dollard SC, Dreon M, Hernandez-Alvarado N, et al.

JAMA pediatrics 2021; (175(3)):e205441 doi:10.1001/jamapediatrics.2020.5441.

The burden of cytomegalovirus infection remains high in high-risk kidney transplant recipients despite six-month valganciclovir prophylaxis.

Räihä J, Ortiz F, Mannonen L, et al.

Transplant infectious disease : an official journal of the Transplantation Society 2021; (23(4)):e13577 doi:10.1111/tid.13577.

Spotlight on Impactful Research: Low-Dose Valganciclovir for Cytomegalovirus Prophylaxis in Intermediate-Risk Liver Transplantation Recipients.

Loy V

Clinical liver disease 2021; (17(2)):53-56 doi:10.1002/cld.962.

Brain MRI findings in newborns with congenital cytomegalovirus infection: results from a large cohort study.

Vande Walle C, Keymeulen A, Schiettecatte E, et al.

European radiology 2021; (31(10)):8001-8010 doi:10.1007/s00330-021-07776-2.

Cytomegalovirus-A Risk Factor for Childhood Hearing Loss: A Systematic Review.

Vos B, Noll D, Whittingham J, et al.

Ear and hearing 2021; (42(6)):1447-1461 doi:10.1097/AUD.0000000000001055.

Clinical outcome and the role of antivirals in congenital cytomegalovirus infection.

Ross SA, Kimberlin D

Antiviral research 2021; (191()):105083 doi:10.1016/j.antiviral.2021.105083.

A BMPR2/YY1 Signaling Axis Is Required for Human Cytomegalovirus Latency in Undifferentiated Myeloid Cells.

Poole E, Carlan da Silva MC, Huang C, et al.

mBio 2021; (12(3)):e0022721 doi:10.1128/mBio.00227-21.

Cytomegalovirus seroprevalence among blood donors: a systematic review and meta-analysis.

Adane T, Getawa S

The Journal of international medical research 2021; (49(8)):3000605211034656 doi:10.1177/03000605211034656.

Renal toxicity of high-dosage valacyclovir for secondary prevention of congenital cytomegalovirus infection: a dose regimen-related issue.

Ville Y, Leruez-Ville M

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2021; (58(4)):637-638 doi:10.1002/uog.24753.

Congenital Cytomegalovirus and Hepatic Failure: An Underrecognized Complication.

Souder JP, Grimm E, Pinninti S, et al.

The Pediatric infectious disease journal 2022; (41(2)):e49-e53 doi:10.1097/INF.0000000000003381.

Amniocentesis to diagnose congenital cytomegalovirus infection following maternal primary infection.

Dinsmoor MJ, Fette LM, Hughes BL, et al.

American journal of obstetrics & gynecology MFM 2022; (4(4)):100641 doi:10.1016/j.ajogmf.2022.100641.

Congenital cytomegalovirus infection with brainstem hemorrhage and polymicrogyria: Necropsic and histopathological findings.

Arredondo Montero J, Bronte Anaut M, Caballero Martínez MC, et al.

Congenital anomalies 2022; (62(6)):248-253 doi:10.1111/cga.12488.

Congenital cytomegalovirus infection diagnostics and management.

Pinninti S, Boppana S

Current opinion in infectious diseases 2022; (35(5)):436-441 doi:10.1097/QCO.0000000000000874.

Maribavir for the Management of Cytomegalovirus in Adult Transplant Recipients: A Review of the Literature and Practical Considerations.

Kleiboeker HL, Descourouez JL, Schulz LT, et al.

The Annals of pharmacotherapy 2023; (57(5)):597-608 doi:10.1177/10600280221118959.

High Monocyte Count Associated with Human Cytomegalovirus Replication In Vivo and Glucocorticoid Therapy May Be a Hallmark of Disease.

Zdziarski P, Gamian A

International journal of molecular sciences 2022; (23(17)) doi:10.3390/ijms23179595.

Emergency gastrointestinal tract operation associated with cytomegalovirus infection.

Kim S, Yoon KW, Gil E, et al.

Annals of surgical treatment and research 2023; (104(2)):119-125 doi:10.4174/astr.2023.104.2.119.

Rethinking human cytomegalovirus latency reservoir.

Schwartz M, Stern-Ginossar N

Annals of the New York Academy of Sciences 2023; (1524(1)):30-36 doi:10.1111/nyas.14994.

Congenital Cytomegalovirus Infection Screening in Newborns From Saliva Samples by Real-Time Polymerase Chain Reaction Analysis.

Günlemez A, Kolaylı F, Yazıcı Özçelik E, et al.

Turkish archives of pediatrics 2023; (58(4)):371-375 doi:10.5152/TurkArchPediatr.2023.22309.

Counseling in fetal medicine: Congenital cytomegalovirus infection.

D'Alberti E, Rizzo G, Khalil A, et al.

European journal of obstetrics, gynecology, and reproductive biology 2024; (295()):8-17 doi:10.1016/j.ejogrb.2024.01.037.

CMV-induced Hearing Loss.

Singh S, Maheshwari A, Boppana S

Newborn (Clarksville, Md.) 2023; (2(4)):249-262 doi:10.5005/jp-journals-11002-0081.

Fetal Cytomegalovirus Infection in the Absence of Maternal Cytomegalovirus-IgM Seropositivity.

Erenel H, Tuna G, Alpay V, Polat İ

Reproductive sciences (Thousand Oaks, Calif.) 2024; (31(6)):1533-1540 doi:10.1007/s43032-024-01487-x.

Current and Emerging Antiviral Agents in the Prevention and Treatment of Cytomegalovirus in Pediatric Transplant Recipients.

Valencia Deray KG, Danziger-Isakov LA, Downes KJ

Journal of the Pediatric Infectious Diseases Society 2024; (13(Supplement_1)):S14-S21 doi:10.1093/jpids/piad059.

Estimated cytomegalovirus seroprevalence in the general population of the United States and Canada.

Dana Flanders W, Lally C, Dilley A, Diaz-Decaro J

Journal of medical virology 2024; (96(3)):e29525 doi:10.1002/jmv.29525.

Late cytomegalovirus disease after hematopoietic cell transplantation: significance of novel transplantation techniques.

Sadowska-Klasa A, Özkök S, Xie H, et al.

Blood advances 2024; (8(14)):3639-3651 doi:10.1182/bloodadvances.2023012175.

Adequate antiviral treatment lowers overall complications of cytomegalovirus colitis among inpatients with inflammatory bowel diseases.

Hsieh CR, Wu RC, Kuo CJ, et al.

BMC infectious diseases 2024; (24(1)):443 doi:10.1186/s12879-024-09317-w.

From diagnosis to management: current perspectives on congenital cytomegalovirus infection.

Buchfellner M, Ross S

Current opinion in infectious diseases 2024; (37(4)):232-237 doi:10.1097/QCO.0000000000001023.

Cytomegalovirus (CMV) Polyradiculopathy: An Important "AIDS-Defining" Illness Complication.

Finessi A, Aziz MA, Izquierdo-Pretel G, Bracho A

Cureus 2024; (16(4)):e58230 doi:10.7759/cureus.58230.

Cytomegalovirus infection and cardiovascular outcomes in abdominal organ transplant recipients: A systematic review and meta-analysis.

Arvanitis P, Davis MR, Farmakiotis D

Transplantation reviews (Orlando, Fla.) 2024; (38(4)):100860 doi:10.1016/j.trre.2024.100860.

Incidence and outcomes of cytomegalovirus reactivation after chimeric antigen receptor T-cell therapy.

Lin RY, Anderson AD, Natori Y, et al.

Blood advances 2024; (8(14)):3813-3822 doi:10.1182/bloodadvances.2024012922.

Immune recovery uveitis: an ocular manifestation in HIV/AIDS receiving treatment.

Dionson MM

Current opinion in ophthalmology 2024; (35(6)):507-512 doi:10.1097/ICU.0000000000001078.

Human cytomegalovirus and neonatal infection.

Lawrence SM

Current research in microbial sciences 2024; (7()):100257 doi:10.1016/j.crmicr.2024.100257.

High seroprevalence of CMV among Algerian hemodialysis patients and the general population: Intermediate-risk patients for post-transplant CMV infection.

Lamara Mahammed L, Omrani Z, Bellachia N, et al.

Transplant immunology 2025; (88()):102168 doi:10.1016/j.trim.2024.102168.

Ultrasound features of congenital cytomegalovirus infection in the first trimester: A case report.

Chen XL, Zhang LQ, Bai LL

World journal of clinical cases 2025; (13(5)):97629 doi:10.12998/wjcc.v13.i5.97629.

Investigation of the infection route of HIV-associated cytomegalovirus retinitis.

Cai J, Xie ZK, Tang DY, et al.

International journal of ophthalmology 2025; (18(3)):478-486 doi:10.18240/ijo.2025.03.15.

Deciphering Positive Cytomegalovirus Immunoglobulin M Test Results in Immunocompetent Adults Hospitalized With Illness Suspicious for Acute Cytomegalovirus Infection: A Multihospital Study.

Samuel S, Thomas S, Asleson L, et al.

Open forum infectious diseases 2025; (12(3)):ofaf144 doi:10.1093/ofid/ofaf144.

Neuron-restricted cytomegalovirus latency in the central nervous system regulated by CD4+ T-cells and IFN-γ.

Krstanović F, Mihalić A, Rashidi AS, et al.

Journal of neuroinflammation 2025; (22(1)):95 doi:10.1186/s12974-025-03422-6.

[Secondary Prevention of Fetal Cytomegalovirus Infection Through Valacyclovir Administration in Maternal Primary Infections During the Periconceptional Period and First Trimester of Pregnancy].

Chatzakis C, Bourgon N, Leruez-Ville M, Ville Y

Gynecologie, obstetrique, fertilite & senologie 2025; (53(7-8)):341-348 doi:10.1016/j.gofs.2025.03.010.

Congenital cytomegalovirus retinitis of prematurity: a case report and literature review.

Li Y, Sun W, Jin X, et al.

Frontiers in pediatrics 2025; (13()):1558820 doi:10.3389/fped.2025.1558820.

CMV retinitis in HIV-infected patients: Plasma viral load utility in diagnosis.

Benadda S, Achour N, Ziane H, Kezzal K

Diagnostic microbiology and infectious disease 2025; (113(2)):116926 doi:10.1016/j.diagmicrobio.2025.116926.

Human Cytomegalovirus UL78 is a Nuclear-Localized GPCR Necessary for Efficient Reactivation from Latent Infection in CD34+ Hematopoietic Progenitor Cells.

Medica S, Diggins NL, Denton M, et al.

bioRxiv : the preprint server for biology 2025; doi:10.1101/2025.06.02.657350.

Estimating Risks of Central Nervous System Disturbance Associated with Medications for Herpes Zoster: Findings from a Regional Population-Based Cohort Study Using the Shizuoka Kokuho Database.

Hagiwara R, Nakatani E, Kaneda H, et al.

Drugs - real world outcomes 2025; (12(3)):399-410 doi:10.1007/s40801-025-00500-2.

The impact of recent Covid-19 infection on cytomegalovirus antibodies.

Dan W, Yuzhu X, Han W, et al.

Journal of infection and public health 2025; (18(10)):102848 doi:10.1016/j.jiph.2025.102848.

Defining a CMV viral load threshold for pre-emptive therapy in paediatric haematopoietic stem cell transplant recipients.

Duret A, Charles O, Margetts BK, et al.

British journal of haematology 2025; (207(3)):911-919 doi:10.1111/bjh.20254.

Vestibular Dysfunction in Pediatric Patients With Congenital Cytomegalovirus Infection and Hearing Loss: Occurrence and Characteristics.

Zhou G, Peterson H, Yun A, Brodsky J

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2025; (46(9)):1124-1128 doi:10.1097/MAO.0000000000004600.

Changes in Neutrophil Count During Valganciclovir Therapy for Symptomatic Congenital Cytomegalovirus Infection.

Kawamura A, Abe S, Shirai K, et al.

Biomedicines 2025; (13(7)) doi:10.3390/biomedicines13071739.

Letermovir and Tacrolimus Drug-Drug Interaction in a Pediatric Kidney Transplant Patient: A Case Report and Review of the Literature.

Berger I, Matsuda-Abedini M, Haubrich K

Pediatric transplantation 2025; (29(6)):e70143 doi:10.1111/petr.70143.

Diagnostic Performance of Salivary PCR for the Detection of Congenital Cytomegalovirus: A Systematic Review and Meta-Analysis.

Rady SMA, Abdelmoati MI, Sabra S, et al.

Viruses 2025; (17(9)) doi:10.3390/v17091253.

Utility of cytomegalovirus (CMV) qualitative polymerase chain reaction from gastrointestinal biopsies in diagnosis of CMV gastrointestinal disease: A 10-year retrospective study.

Schonhofer C, Lo CK, Owen DR, et al.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2025; (181()):105879 doi:10.1016/j.jcv.2025.105879.

The effect of valacyclovir on secondary prevention of congenital cytomegalovirus infection.

Chatzakis C, Bourgon N, Fourgeaud J, et al.

Best practice & research. Clinical obstetrics & gynaecology 2025; (103()):102679 doi:10.1016/j.bpobgyn.2025.102679.

Associations Between Fetal Symptoms During Pregnancy and Neonatal Clinical Complications with Cytomegalovirus Infection.

Bartek V, Csire M, Kiss G, et al.

Children (Basel, Switzerland) 2025; (12(12)) doi:10.3390/children12121690.

Prevalence and Risk Factors for Cytomegalovirus Retinitis Among People Living with HIV in Sub-Saharan Africa in the Antiretroviral Therapy Era: A Systematic Review and Meta-Analysis.

Ismail MF, Khalafalla I, Sheck ZO, et al.

Scientific reports 2026; (16(1)).