Research & Literature

Darier disease: A fold (intertriginous) dermatosis.

Engin B, Kutlubay Z, Erkan E, Tüzün Y

Clinics in dermatology 2015; (33(4)):448-51.

SERCA2 Haploinsufficiency in a Mouse Model of Darier Disease Causes a Selective Predisposition to Heart Failure.

Prasad V, Lorenz JN, Lasko VM, et al.

BioMed research international 2015; (2015()):251598 doi:10.1155/2015/251598.

Darier disease in Israel: combined evaluation of genetic and neuropsychiatric aspects.

Dodiuk-Gad RP, Cohen-Barak E, Khayat M, et al.

The British journal of dermatology 2016; (174(3)):562-8 doi:10.1111/bjd.14220.

Dye Laser Treatment for Darier Disease: Results of a Case Series.

Cannarozzo G, Bonciani D, Sannino M, et al.

Photomedicine and laser surgery 2016; (34(7)):305-7 doi:10.1089/pho.2015.4034.

Acantholytic dermatosis of the vagina: the diagnostic challenge of acantholytic disease in the genital region.

Kentley J, Cerio R, Khorshid M, Gibbon K

Clinical and experimental dermatology 2017; (42(2)):189-191 doi:10.1111/ced.13026.

Darier-White disease.

Christman MP, Reider E, Kim RH, et al.

Dermatology online journal 2016; (22(12)).

Acral Hemorrhagic Darier Disease.

Flores-Terry MÁ, García-Arpa M, Llamas-Velasco M, et al.

Actas dermo-sifiliograficas 2017; (108(7)):e49-e52 doi:10.1016/j.ad.2017.02.012.

Rare ocular manifestations in keratosis follicularis (Darier-White disease).

Kanakpur SH, Caculo DU

Indian journal of ophthalmology 2017; (65(9)):874-876 doi:10.4103/ijo.IJO_852_16.

Darier disease: A rare genodermatosis.

Suryawanshi H, Dhobley A, Sharma A, Kumar P

Journal of oral and maxillofacial pathology : JOMFP 2017; (21(2)):321 doi:10.4103/jomfp.JOMFP_170_16.

Sporadic case of Darier disease caused by a novel splice-site mutation in the ATP2A2 gene.

Yasuno S, Miyoshi Y, Asano N, et al.

Clinical and experimental dermatology 2019; (44(2)):e10-e12 doi:10.1111/ced.13806.

Combination of alitretinoin and topical 5-fluorouracil in Darier disease.

Soenen A, Saint-Jean M, Daguzé J, et al.

JAAD case reports 2019; (5(1)):75-77 doi:10.1016/j.jdcr.2018.09.024.

[Detection and analysis of an ATP2A2 mutation in a family with Darier-White disease].

Chen X, Liu Q, Sun M, et al.

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 2019; (36(8)):794-797 doi:10.3760/cma.j.issn.1003-9406.2019.08.010.

Eczema herpeticum in Darier's disease: a topical storm.

Tayabali K, Pothiwalla H, Lowitt M

Journal of community hospital internal medicine perspectives 2019; (9(4)):347-350 doi:10.1080/20009666.2019.1650590.

Darier Disease - A Clinical Illustration of Its High Variable Expressivity.

Beiu C, Giurcaneanu C, Mihai M, et al.

Cureus 2019; (11(12)):e6292 doi:10.7759/cureus.6292.

Darier disease is associated with heart failure: a cross-sectional case-control and population based study.

Bachar-Wikstrom E, Curman P, Ahanian T, et al.

Scientific reports 2020; (10(1)):6886 doi:10.1038/s41598-020-63832-9.

Darier disease: long-term treatment with systemic retinoids at a tertiary hospital.

Vieira ML, de Paula Samorano L, da Matta Rivitti-Machado MC, de Oliveira ZNP

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2020; (18(6)):628-630 doi:10.1111/ddg.14113.

Type 1 Segmental Darier Disease: Case Report and Discussion of the Treatment Options.

Alsharif SH, Alesa D, Baabdullah A

Case reports in dermatology 2020; (12(3)):159-167 doi:10.1159/000509177.

Management of Darier disease: A review of the literature and update.

Haber RN, Dib NG

Indian journal of dermatology, venereology and leprology 2021; (87(1)):14-21.

Darier Disease - A Multi-organ Condition?

Bachar-Wikström E, Wikström JD

Acta dermato-venereologica 2021; (101(4)):adv00430 doi:10.2340/00015555-3770.

An Update on the Cutaneous Manifestations of Darier Disease.

Yeshurun A, Ziv M, Cohen-Barak E, et al.

Journal of cutaneous medicine and surgery 2021; (25(5)):498-503 doi:10.1177/1203475421999331.

Ophthalmic Assessment in Patients With Darier Disease.

Hammad H, Adler E, Yeshurun A, et al.

American journal of ophthalmology 2021; (227()):139-142 doi:10.1016/j.ajo.2021.03.011.

Patients with Darier Disease Exhibit Cognitive Impairment while Patients with Hailey-Hailey Disease Do Not: An Experimental, Matched Case-control Study.

Curman P, Bern J, Sand L, et al.

Acta dermato-venereologica 2021; (101(6)):adv00476 doi:10.2340/00015555-3818.

Hailey-Hailey disease treated with dupilumab: a case series.

Alzahrani N, Grossman-Kranseler J, Swali R, et al.

The British journal of dermatology 2021; (185(3)):680-682 doi:10.1111/bjd.20475.

Beyond the skin involvement in Darier disease: A complicated neuropsychiatric phenotype.

Li Pomi F, Motolese A, Bertino L, et al.

Clinical case reports 2021; (9(6)):e04263 doi:10.1002/ccr3.4263.

An Infant With Seborrhoeic Dermatitis and Eczema Herpeticum Complicated by a Generalized Infection.

Karpierz K, Kuchar EP

Cureus 2021; (13(8)):e16818 doi:10.7759/cureus.16818.

Correcting a 30-year diagnosis: A report of vesiculobullous Darier disease previously diagnosed as pemphigus vulgaris.

Ashbaugh AG, Doong J, Lee B, Rojek NW

International journal of women's dermatology 2021; (7(4)):492-493 doi:10.1016/j.ijwd.2021.02.001.

Darier and Hailey-Hailey disease: update 2021.

Rogner DF, Lammer J, Zink A, Hamm H

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2021; (19(10)):1478-1501 doi:10.1111/ddg.14619.

Whole-transcriptome sequencing identifies postzygotic ATP2A2 mutations in a patient misdiagnosed with herpes zoster, confirming the diagnosis of very late-onset segmental Darier disease.

Mohaghegh F, Youssefian L, Galehdari H, et al.

Experimental dermatology 2022; (31(6)):943-948 doi:10.1111/exd.14559.

Darier Disease with Psoriasis.

Kang SY, Lee SY, Park JS, et al.

Medicina (Kaunas, Lithuania) 2022; (58(7)) doi:10.3390/medicina58070902.

Diagnostics of autoimmune blistering disorders: an experience of a single tertiary referral centre.

Adaszewska A, Woźniak K, Kalińska-Bienias A, et al.

Postepy dermatologii i alergologii 2022; (39(3)):446-453 doi:10.5114/ada.2020.99972.

Retinoid-induced skeletal hyperostosis in disorders of keratinization.

Doolan BJ, Paolino A, Greenblatt DT, Mellerio JE

Clinical and experimental dermatology 2022; (47(12)):2273-2276 doi:10.1111/ced.15382.

Subcellular compartmentalization of STIM1 for the distinction of Darier disease from Hailey-Hailey disease.

Stanisz H, Mitteldorf C, Janning H, et al.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2022; (20(12)):1613-1619 doi:10.1111/ddg.14912.

Association of Somatic ATP2A2 Damaging Variants With Grover Disease.

Seli D, Ellis KT, Goldust M, et al.

JAMA dermatology 2023; (159(7)):745-749 doi:10.1001/jamadermatol.2023.1139.

Keratosis follicularis (Darier disease) - clinical characteristics and treatment - a review and update.

Chyl-Surdacka K, Borzęcki A, Latifa J, et al.

Postepy dermatologii i alergologii 2023; (40(3)):337-340 doi:10.5114/ada.2022.124344.

Targeting SERCA2 in organotypic epidermis reveals MEK inhibition as a therapeutic strategy for Darier disease.

Zaver SA, Sarkar MK, Egolf S, et al.

JCI insight 2023; (8(18)).

Impact of the 2018 revised Pregnancy Prevention Programme by the European Medicines Agency on the use of oral retinoids in females of childbearing age in Denmark, Italy, Netherlands, and Spain: an interrupted time series analysis.

Durán CE, Riera-Arnau J, Abtahi S, et al.

Frontiers in pharmacology 2023; (14()):1207976 doi:10.3389/fphar.2023.1207976.

Diagnosis and management of vulvar Darier disease: A case report.

Evruke I, Ugurlucan FG, Erdem BY, Sari SO

Case reports in women's health 2023; (39()):e00545 doi:10.1016/j.crwh.2023.e00545.

ALA-PDT combined with 2940 nm ablative fractional Er:YAG laser for Darier's disease.

Gao T, Xiao J, Pan N, et al.

Photodiagnosis and photodynamic therapy 2024; (45()):103892 doi:10.1016/j.pdpdt.2023.103892.

Efficacy of alitretinoin in the treatment of Darier disease: a case report.

Pagon A, Dolenc Voljč M

Acta dermatovenerologica Alpina, Pannonica, et Adriatica 2023; (32(4)):191-195.

Exacerbation of Darier disease with lithium therapy.

Tamazian S, Simpson CL

Dermatology online journal 2023; (29(5)) doi:10.5070/D329562405.

[Clinical, therapeutic and pathophysiological aspects of Darier's disease].

Bernard P, Blanchard M, Morren MA, Guenova E

Revue medicale suisse 2024; (20(867)):659-663 doi:10.53738/REVMED.2024.20.867.659.

Darier disease: Histopathology revisited.

Manohar A, Antony M, Tirumalae R, Kalegowda IY

Indian journal of pathology & microbiology 2024; (67(3)):615-618 doi:10.4103/ijpm.ijpm_610_23.

Concordance of clinical, histopathologic and direct Immunofluorescence findings in patients with intraepidermal immunobullous disorders.

Ashraf E, Shareef F

JPMA. The Journal of the Pakistan Medical Association 2024; (74(3)):509-512 doi:10.47391/JPMA.9509.

Dantrolene corrects cellular disease features of Darier disease and may be a novel treatment.

Hunt M, Wang N, Pupinyo N, et al.

EMBO molecular medicine 2024; (16(9)):1986-2001 doi:10.1038/s44321-024-00104-3.

Segmental Darier's Disease Treated With Cryotherapy.

Nguyen N, Liu K, Sasson M, Bellucci K

Cureus 2024; (16(10)):e72068 doi:10.7759/cureus.72068.

Darier disease: Current insights and challenges in pathogenesis and management.

Ettinger M, Kimeswenger S, Deli I, et al.

Journal of the European Academy of Dermatology and Venereology : JEADV 2025; (39(5)):942-951 doi:10.1111/jdv.20448.

Patients with Darier disease have an increased risk of keratinocyte carcinoma: a Swedish registry-based nationwide cohort study.

Inci R, Gillstedt M, Kallionpää RA, et al.

Orphanet journal of rare diseases 2024; (19(1)):463 doi:10.1186/s13023-024-03497-z.

Kaposi's Varicelliform Eruption: A Serious and Potentially Fatal Complication of Darier's Disease.

Domingos RR, Reboredo P, Monteiro AS, Sousa C

Cureus 2025; (17(2)):e79077 doi:10.7759/cureus.79077.

Pruritus and Neuropsychiatric Symptoms Among Patients with Darier Disease-An Overlooked and Interconnected Challenge.

Xiong G, Sachdeva M, Yosipovitch G, et al.

Journal of clinical medicine 2025; (14(6)) doi:10.3390/jcm14061818.

Trametinib as a promising therapy for Darier disease: case report.

Soto-García D, Dávila-Seijo P, González-Moure C, et al.

The British journal of dermatology 2025; (193(2)):339-341 doi:10.1093/bjd/ljaf160.

Increased caries risk in a Xerostomic patient with Darier disease: a case report of incipient and advanced carious lesions.

Giannakopoulos K, Lambrou P, Kaklamanos EG, Christodoulou MN

Oxford medical case reports 2025; (2025(5)):omaf042 doi:10.1093/omcr/omaf042.

Retrospective Analysis of Nail Changes and Comorbidities in Darier Disease.

Zhou MH, Zhu AY, Xing Y, Lipner SR

Skin appendage disorders 2025; doi:10.1159/000549631.

Vitamins and the skin: Vitamin A and retinoids in dermatology.

Dessinioti C, Katsambas A

Clinics in dermatology 2026; (44(2)):212-222 doi:10.1016/j.clindermatol.2026.02.005.