Research & Literature

Increasing Incidence of Ehrlichiosis in the United States: A Summary of National Surveillance of Ehrlichia chaffeensis and Ehrlichia ewingii Infections in the United States, 2008-2012.

Nichols Heitman K, Dahlgren FS, Drexler NA, et al.

The American journal of tropical medicine and hygiene 2016; (94(1)):52-60 doi:10.4269/ajtmh.15-0540.

Undetermined Human Ehrlichiosis and Anaplasmosis in the United States, 2008-2012: A Catch-All for Passive Surveillance.

Dahlgren FS, Heitman KN, Behravesh CB

The American journal of tropical medicine and hygiene 2016; (94(2)):299-301 doi:10.4269/ajtmh.15-0691.

Successful Treatment of Human Monocytic Ehrlichiosis with Rifampin.

Abusaada K, Ajmal S, Hughes L

Cureus 2016; (8(1)):e444 doi:10.7759/cureus.444.

Detection of Borrelia miyamotoi and other tick-borne pathogens in human clinical specimens and Ixodes scapularis ticks in New York State, 2012-2015.

Wroblewski D, Gebhardt L, Prusinski MA, et al.

Ticks and tick-borne diseases 2017; (8(3)):407-411 doi:10.1016/j.ttbdis.2017.01.004.

The end of a dogma: the safety of doxycycline use in young children for malaria treatment.

Gaillard T, Briolant S, Madamet M, Pradines B

Malaria journal 2017; (16(1)):148 doi:10.1186/s12936-017-1797-9.

Tick-Borne Emerging Infections: Ehrlichiosis and Anaplasmosis.

Ismail N, McBride JW

Clinics in laboratory medicine 2017; (37(2)):317-340 doi:10.1016/j.cll.2017.01.006.

Development and Clinical Validation of a Multiplex Real-Time Quantitative PCR Assay for Human Infection by Anaplasma phagocytophilum and Ehrlichia chaffeensis.

Reller ME, Dumler JS

Tropical medicine and infectious disease 2018; (3(1)) doi:10.3390/tropicalmed3010014.

Ehrlichiosis masquerading as thrombotic thrombocytopenic purpura.

Chen D, Cholin L, Jalil BA, El-Kersh K

BMJ case reports 2018; (2018()) doi:10.1136/bcr-2018-226665.

Atypical presentation of human ehrlichiosis and anaplasmosis in children in Israel.

Raibin K, Levy I, Atiya Nasagi Y, et al.

Acta paediatrica (Oslo, Norway : 1992) 2019; (108(9)):1727-1728 doi:10.1111/apa.14882.

[Effectivity of diagnostic methods for the detection of human and canine monocytic ehrlichiosis].

Franco-Zetina M, Adame-Gallegos J, Dzul-Rosado K

Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia 2019; (36(5)):650-655 doi:10.4067/S0716-10182019000500650.

First report of human ehrlichiosis in Turkey.

Emiroğlu M, Çelebi B

The Turkish journal of pediatrics 2019; (61(2)):267-270.

Prevalence of Infection and Co-Infection and Presence of Rickettsial Endosymbionts in Ixodes Scapularis (Acari: Ixodidae) in Connecticut, USA.

Pokutnaya D, Molaei G, Weinberger DM, et al.

The Journal of parasitology 2020; (106(1)):30-37.

From Tick Bite to Heart Failure: Ehrlichial Myocarditis.

Almaddah NK, Rawal A, Ardeshna D, et al.

CJC open 2019; (1(6)):327-329 doi:10.1016/j.cjco.2019.09.003.

Ehrlichiosis in a recent kidney transplant recipient: The repellent that did not repel! A case report and literature review of ehrlichiosis in solid organ transplant patients.

Masterson EM, Gupta S, Jakharia N, Peacock JE

Transplant infectious disease : an official journal of the Transplantation Society 2020; (22(4)):e13299 doi:10.1111/tid.13299.

Tickborne Diseases: Diagnosis and Management.

Pace EJ, O'Reilly M

American family physician 2020; (101(9)):530-540.

Ehrlichiosis infection mimicking thrombotic microangiopathy syndrome early after kidney transplantation.

Hassan W, Talwar M, Balaraman V, Molnar MZ

Transplant infectious disease : an official journal of the Transplantation Society 2020; (22(5)):e13305 doi:10.1111/tid.13305.

A novel Ehrlichia strain (Rickettsiales: Anaplasmataceae) detected in Amblyomma triste (Acari: Ixodidae), a tick species of public health importance in the Southern Cone of America.

Cicuttin GL, De Salvo MN, Pérez PD, et al.

Pathogens and global health 2020; (114(6)):318-322 doi:10.1080/20477724.2020.1795579.

Incidence and treatment of hemophagocytic lymphohistiocytosis in hospitalized children with Ehrlichia infection.

Cabler SS, Hogan PG, Fritz SA, et al.

Pediatric blood & cancer 2020; (67(10)):e28436 doi:10.1002/pbc.28436.

Targeted Metagenomics for Clinical Detection and Discovery of Bacterial Tick-Borne Pathogens.

Kingry L, Sheldon S, Oatman S, et al.

Journal of clinical microbiology 2020; (58(11)) doi:10.1128/JCM.00147-20.

Hemophagocytic Lymphohistiocytosis Secondary to Ehrlichia Chaffeensis in Adults: A Case Series From Oklahoma.

Agudelo Higuita NI, Yuen C

The American journal of the medical sciences 2021; (361(2)):269-273 doi:10.1016/j.amjms.2020.08.029.

Gastrointestinal and hepatic symptoms of tickborne diseases.

Budzáková M, Trna J

Vnitrni lekarstvi 2020; (66(4)):232-235.

Assessment of Risk Factors and Outcomes of Severe Ehrlichiosis Infection.

Kuriakose K, Pettit AC, Schmitz J, et al.

JAMA network open 2020; (3(11)):e2025577 doi:10.1001/jamanetworkopen.2020.25577.

Fever, pancytopenia, and elevated D-dimer in a 95-year-old woman with ehrlichiosis: a case report.

Radcliffe C, Tsay C, Glerum K, et al.

BMC geriatrics 2021; (21(1)):178 doi:10.1186/s12877-021-02129-6.

Development and validation of real-time PCR assays for the detection of Ehrlichia species and E. chaffeensis in clinical specimens.

Chung IH, Austin AL, Kato CY

Journal of microbiological methods 2021; (186()):106225 doi:10.1016/j.mimet.2021.106225.

Ehrlichia-induced hemophagocytic lymphohistiocytosis after autologous stem cell transplant.

Mitma AA, Burgess MJ, van Rhee F

Transplant infectious disease : an official journal of the Transplantation Society 2021; (23(4)):e13621 doi:10.1111/tid.13621.

Human Monocytic Ehrlichiosis Associated With Myocarditis and Hemophagocytic Lymphohistiocytosis.

Dahm CN, Yang BQ, Clark DE, et al.

JACC. Case reports 2020; (2(3)):420-425 doi:10.1016/j.jaccas.2019.12.042.

Donor-derived Ehrlichiosis: 2 Clusters Following Solid Organ Transplantation.

Saha A, Browning C, Dandamudi R, et al.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022; (74(5)):918-923 doi:10.1093/cid/ciab667.

Ehrlichiosis and anaplasmosis subcommittee report to the Tick-borne Disease Working Group.

Dixon DM, Branda JA, Clark SH, et al.

Ticks and tick-borne diseases 2021; (12(6)):101823 doi:10.1016/j.ttbdis.2021.101823.

Citizen Science Provides an Efficient Method for Broad-Scale Tick-Borne Pathogen Surveillance of Ixodes pacificus and Ixodes scapularis across the United States.

Porter WT, Wachara J, Barrand ZA, et al.

mSphere 2021; (6(5)):e0068221 doi:10.1128/mSphere.00682-21.

"Leopards do not change their spots:" tick borne disease symptomology case report.

Abernathy H, Alejo A, Arahirwa V, et al.

BMC infectious diseases 2022; (22(1)):699 doi:10.1186/s12879-022-07683-x.

An Unusual Case of Ehrlichiosis Manifesting With Hyponatremia, Acute Encephalopathy, and Hemophagocytic Lymphohistiocytosis.

Bolling T, Ritter AS, Gupte AA

Cureus 2022; (14(7)):e26943 doi:10.7759/cureus.26943.

Ehrlichia Notch signaling induction promotes XIAP stability and inhibits apoptosis.

Patterson LL, Byerly CD, Solomon R, et al.

bioRxiv : the preprint server for biology 2023; doi:10.1101/2023.01.06.523066.

Ehrlichiosis-Associated Hemophagocytic Lymphohistiocytosis: A Case Series and Review of the Literature.

Hammoud K, Fulmer R, Hamner M, El Atrouni W

Case reports in hematology 2023; (2023()):5521274 doi:10.1155/2023/5521274.

First report of pediatric ehrlichiosis in Mexico.

Cisneros-Saldaña D, Osuna-Álvarez LE, Castillo-Bejarano JI, et al.

Boletin medico del Hospital Infantil de Mexico 2023; (80(Supl 1)):12-22 doi:10.24875/BMHIM.22000056.

Ehrlichia-Induced Hemophagocytic Lymphohistiocytosis (HLH) With No Response to Doxycycline Treatment.

Qasim H, Al-Obaidi A, Khan A, Freter C

Cureus 2023; (15(7)):e42325 doi:10.7759/cureus.42325.

Molecular detection of pathogens from ticks collected from dogs and cats at veterinary clinics in Finland.

Zakham F, Korhonen EM, Puonti PT, et al.

Parasites & vectors 2023; (16(1)):327 doi:10.1186/s13071-023-05864-4.

From Tick to Test: A Comprehensive Review of Tick-Borne Disease Diagnostics and Surveillance Methods in the United States.

Rowan S, Mohseni N, Chang M, et al.

Life (Basel, Switzerland) 2023; (13(10)) doi:10.3390/life13102048.

Non-Canonical Inflammasome Pathway: The Role of Cell Death and Inflammation in Ehrlichiosis.

Sharma AK, Ismail N

Cells 2023; (12(22)) doi:10.3390/cells12222597.

Ehrlichiosis: A Unique Presentation of Fatal Sepsis in an Immunocompetent Adult.

Mazin LN, Peterson CJ, Stewart CA

Cureus 2024; (16(2)):e53932 doi:10.7759/cureus.53932.

Ehrlichia chaffeensis Etf-3 Induces Host RAB15 Upregulation for Bacterial Intracellular Growth.

Yang N, Li M, Qin S, et al.

International journal of molecular sciences 2024; (25(5)) doi:10.3390/ijms25052551.

Hemophagocytic Lymphohistiocytosis (HLH) in Patients with Tick-Borne Illness: A Scoping Review of 98 Cases.

Jevtic D, da Silva MD, Haylock AB, et al.

Infectious disease reports 2024; (16(2)):154-169 doi:10.3390/idr16020012.

Becoming Endemic: Anaplasmosis Imported Across State Borders.

Abraham JD, Wenning HS, Saeed DA, et al.

Cureus 2024; (16(4)):e57902 doi:10.7759/cureus.57902.

Myocarditis Secondary to Human Monocytotrophic Ehrlichiosis.

Kariyawasam V, Shah K

Cureus 2024; (16(4)):e59369 doi:10.7759/cureus.59369.

Neurological manifestations of ehrlichiosis among a cohort of patients: prevalence and clinical symptoms.

Iyamu O, Ciccone EJ, Schulz A, et al.

BMC infectious diseases 2024; (24(1)):701 doi:10.1186/s12879-024-09607-3.

Human monocytotropic ehrlichiosis-A systematic review and analysis of the literature.

Gygax L, Schudel S, Kositz C, et al.

PLoS neglected tropical diseases 2024; (18(8)):e0012377 doi:10.1371/journal.pntd.0012377.

Hemophagocytic Lymphohistiocytosis Due to Ehrlichiosis: A Case Series.

Iyer A, D'Anna M, Verma S, et al.

HCA healthcare journal of medicine 2024; (5(6)):701-706 doi:10.36518/2689-0216.1639.

A case of ehrlichiosis with meningoencephalitis and multi-organ failure.

Al-Bahadili N, Shamasneh I, Meniru C, Nlandu Z

IDCases 2025; (39()):e02165 doi:10.1016/j.idcr.2025.e02165.

Ehrlichiosis Manifesting as Septic Shock and Respiratory Failure With Alveolar Hemorrhage in an Immunocompetent Patient.

Sommers KR, Washburn RG

Cureus 2025; (17(7)):e87581 doi:10.7759/cureus.87581.

Fatal Ehrlichia muris eauclairensis Infection in Liver Transplant Recipient, Minnesota, USA.

Sahra S, Chesdachai S, Vergidis P, et al.

Emerging infectious diseases 2026; (32(1)):148-150 doi:10.3201/eid3201.250893.