Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
Top Authors
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Massachusetts Eye and Ear Infirmary
Boston, United States
Mayo Clinic
Rochester, United States
University of Freiburg
Freiburg im Breisgau, Germany
The University of Sydney
Sydney, Australia
Netherlands Institute for Innovative Ocular Surgery
Rotterdam, The Netherlands
University of Pittsburgh
Pittsburgh, United States
University of Toronto
Toronto, Canada
Sunnybrook Health Science Centre
Toronto, Canada
Doshisha University
Kyoto, Japan
Kyoto Prefectural University of Medicine
Kyoto, Japan
References
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Peripheral Endothelial Cell Count Is a Predictor of Disease Severity in Advanced Fuchs Endothelial Corneal Dystrophy.
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[Clinical and functional results of one-step phaco surgery and central descemetorhexis for cataract and Fuchs primary endothelial corneal dystrophy].
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Corneal Optical Changes Associated with Induced Edema in Fuchs Endothelial Corneal Dystrophy.
Wacker K, McLaren JW, Kane KM, Patel SV
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DMEK versus DSAEK for Fuchs' endothelial dystrophy: A meta-analysis.
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European journal of ophthalmology 2019; (29(1)):15-22 doi:10.1177/1120672118757431.
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Repeatability and Intersession Reproducibility of Pentacam Corneal Thickness Maps in Fuchs Dystrophy and Endothelial Keratoplasty.
Mingo-Botín D, Arnalich-Montiel F, Couceiro de Juan A, Ortiz-Toquero S
Cornea 2018; (37(8)):987-992 doi:10.1097/ICO.0000000000001634.
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Determining Subclinical Edema in Fuchs Endothelial Corneal Dystrophy: Revised Classification using Scheimpflug Tomography for Preoperative Assessment.
Sun SY, Wacker K, Baratz KH, Patel SV
Ophthalmology 2019; (126(2)):195-204 doi:10.1016/j.ophtha.2018.07.005.
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Descemetorhexis Without Endothelial Keratoplasty Versus DMEK for Treatment of Fuchs Endothelial Corneal Dystrophy.
Huang MJ, Kane S, Dhaliwal DK
Cornea 2018; (37(12)):1479-1483 doi:10.1097/ICO.0000000000001742.
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Use of Topical Rho Kinase Inhibitors in the Treatment of Fuchs Dystrophy After Descemet Stripping Only.
Macsai MS, Shiloach M
Cornea 2019; (38(5)):529-534 doi:10.1097/ICO.0000000000001883.
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Histopathology of a retrocorneal membrane after Descemet membrane endothelial keratoplasty: a case report.
Bayyoud T, Rohrbach JM, Bartz-Schmidt KU, Thaler S
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Imaging the Corneal Endothelium in Fuchs Corneal Endothelial Dystrophy.
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Regional variability in corneal endothelial cell density between guttae and non-guttae areas in Fuchs endothelial corneal dystrophy.
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Predicting the Prognosis of Fuchs Endothelial Corneal Dystrophy by Using Scheimpflug Tomography.
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The Rapid Transformation of Transplantation for Corneal Endothelial Diseases: An Evolution From Penetrating to Lamellar to Cellular Transplants.
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Morning Myopic Shift and Glare in Advanced Fuchs Endothelial Corneal Dystrophy.
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Descemet Membrane Endothelial Keratoplasty versus Ultrathin Descemet Stripping Automated Endothelial Keratoplasty: A Multicenter Randomized Controlled Clinical Trial.
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Fuchs endothelial corneal dystrophy: The vicious cycle of Fuchs pathogenesis.
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Progress in retinal and eye research 2021; (80()):100863 doi:10.1016/j.preteyeres.2020.100863.
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Descemet Stripping Only Supplemented With Topical Ripasudil for Fuchs Endothelial Dystrophy 12-Month Outcomes of the Sydney Eye Hospital Study.
Moloney G, Garcerant Congote D, Hirnschall N, et al.
Cornea 2021; (40(3)):320-326 doi:10.1097/ICO.0000000000002437.
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Molecular Mechanisms of Fuchs and Congenital Hereditary Endothelial Corneal Dystrophies.
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Reviews of physiology, biochemistry and pharmacology 2020; (178()):41-81 doi:10.1007/112_2020_39.
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Update on the Surgical Management of Fuchs Endothelial Corneal Dystrophy.
Blitzer AL, Colby KA
Ophthalmology and therapy 2020; (9(4)):757-765 doi:10.1007/s40123-020-00293-3.
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New severity grading system for Fuchs endothelial corneal dystrophy using anterior segment optical coherence tomography.
Yasukura Y, Oie Y, Kawasaki R, et al.
Acta ophthalmologica 2021; (99(6)):e914-e921 doi:10.1111/aos.14690.
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Disease Expression and Familial Transmission of Fuchs Endothelial Corneal Dystrophy With and Without CTG18.1 Expansion.
Xu TT, Li YJ, Afshari NA, et al.
Investigative ophthalmology & visual science 2021; (62(1)):17 doi:10.1167/iovs.62.1.17.
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Diseases of the corneal endothelium.
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Experimental eye research 2021; (205()):108495 doi:10.1016/j.exer.2021.108495.
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Descemet Membrane Endothelial Keratoplasty versus Descemet Stripping Automated Endothelial Keratoplasty in Complicated Vitrectomized Eyes.
Mimouni M, Sorkin N, Slomovic J, et al.
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Pilot Study of Corneal Clearance With the Use of a Rho-Kinase Inhibitor After Descemetorhexis Without Endothelial Keratoplasty for Fuchs Endothelial Corneal Dystrophy.
Davies E, Jurkunas U, Pineda R
Cornea 2021; (40(7)):899-902 doi:10.1097/ICO.0000000000002691.
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Hyperosmolar Eye Drops for Diurnal Corneal Edema in Fuchs' Endothelial Dystrophy: A Double-Masked, Randomized Controlled Trial.
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The "Two-Flaps" Technique for Descemet Stripping Only.
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Cornea 2021; (40(9)):1211-1214 doi:10.1097/ICO.0000000000002744.
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Genetic mutations and molecular mechanisms of Fuchs endothelial corneal dystrophy.
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Eye and vision (London, England) 2021; (8(1)):24 doi:10.1186/s40662-021-00246-2.
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Long-term Outcomes in Fellow Eyes Comparing DSAEK and DMEK for Treatment of Fuchs Corneal Dystrophy.
Weisenthal RW, Yin HY, Jarstad AR, et al.
American journal of ophthalmology 2022; (233()):216-226 doi:10.1016/j.ajo.2021.06.013.
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Challenges in the complex management of post-keratoplasty glaucoma.
Anders LM, Gatzioufas Z, Grieshaber MC
Therapeutic advances in ophthalmology 2021; (13()):25158414211031397 doi:10.1177/25158414211031397.
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Is there a genetic link between Keratoconus and Fuch's endothelial corneal dystrophy?
Gurnani B, Kaur K, Tripathy K
Medical hypotheses 2021; (157()):110699 doi:10.1016/j.mehy.2021.110699.
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Cataract surgery and intraocular lens placement in patients with Fuchs corneal dystrophy: a review of the current literature.
Moshirfar M, Huynh R, Ellis JH
Current opinion in ophthalmology 2022; (33(1)):21-27 doi:10.1097/ICU.0000000000000816.
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Demographic profile and clinical course of Fuchs endothelial corneal dystrophy in Mexican patients.
Barrera-Sanchez M, Hernandez-Camarena JC, Ruiz-Lozano RE, et al.
International ophthalmology 2022; (42(4)):1299-1309 doi:10.1007/s10792-021-02117-0.
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Therapeutic contact lens for Fuchs endothelial corneal dystrophy: Monitoring with Scheimpflug tomography.
Erdinest N, London N, Levinger N, Lavy I
American journal of ophthalmology case reports 2022; (25()):101242 doi:10.1016/j.ajoc.2021.101242.
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Reticular epithelial corneal edema as a novel side-effect of Rho Kinase Inhibitors: An Indian scenario.
Bhargava M, Sen S, Bhambhani V, et al.
Indian journal of ophthalmology 2022; (70(4)):1163-1170 doi:10.4103/ijo.IJO_2865_21.
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Surgical Management of Fuchs Endothelial Corneal Dystrophy: A Treatment Algorithm and Individual Patient Meta-Analysis of Descemet Stripping Only.
Din N, Cohen E, Popovic M, et al.
Cornea 2022; (41(9)):1188-1195 doi:10.1097/ICO.0000000000002975.
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Fuchs endothelial corneal dystrophy: current perspectives on diagnostic pathology and genetics-Bowman Club Lecture.
Thaung C, Davidson AE
BMJ open ophthalmology 2022; (7(1)) doi:10.1136/bmjophth-2022-001103.
PMID: 36161831 - 52
The soil and the seed: The relationship between Descemet's membrane and the corneal endothelium.
Petrela RB, Patel SP
Experimental eye research 2023; (227()):109376 doi:10.1016/j.exer.2022.109376.
PMID: 36592681 - 53
Recurrence of Guttae and Endothelial Dysfunction After Successful Descemet Stripping Only in Fuchs Dystrophy.
Kaufman AR, Bal S, Boakye J, Jurkunas UV
Cornea 2023; (42(8)):1037-1040 doi:10.1097/ICO.0000000000003221.
PMID: 36729028 - 54
Descemet Stripping Without Endothelial Keratoplasty in Early-Stage Central Fuchs Endothelial Dystrophy: Long-term Results.
Vieira R, Castro C, Coelho J, et al.
Cornea 2023; (42(8)):980-985 doi:10.1097/ICO.0000000000003131.
PMID: 36731082 - 55
Long-Term Outcomes of Descemet Membrane Endothelial Keratoplasty: Effect of Surgical Indication and Disease Severity.
Vasiliauskaite I, Kocaba V, van Dijk K, et al.
Cornea 2023; (42(10)):1229-1239 doi:10.1097/ICO.0000000000003130.
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Risk Factors for Descemet Membrane Endothelial Keratoplasty Rejection: Current Perspectives- Systematic Review.
Gurnani B, Kaur K, Lalgudi VG, Tripathy K
Clinical ophthalmology (Auckland, N.Z.) 2023; (17()):421-440 doi:10.2147/OPTH.S398418.
PMID: 36755886 - 57
Ten-Year Changes in Vision, Refractive Error, and Corneal Thickness After Descemet Stripping Automated Endothelial Keratoplasty for Fuchs Endothelial Corneal Dystrophy.
Patel SV, Hodge DO, Nau CB
Cornea 2024; (43(2)):233-236 doi:10.1097/ICO.0000000000003289.
PMID: 37018761 - 58
Comparison of Long-Term Outcomes of DSEK and DMEK in Fuchs Endothelial Dystrophy.
Fu L, Hollick EJ
Cornea 2024; (43(2)):184-189 doi:10.1097/ICO.0000000000003310.
PMID: 37170402 - 59
Association Between Fuchs Endothelial Corneal Dystrophy, Diabetes Mellitus, and Multimorbidity.
Nealon CL, Halladay CW, Gorman BR, et al.
Cornea 2023; (42(9)):1140-1149 doi:10.1097/ICO.0000000000003311.
PMID: 37170406 - 60
Multi-ancestry GWAS of Fuchs corneal dystrophy highlights roles of laminins, collagen, and endothelial cell regulation.
Peachey N, Gorman B, Francis M, et al.
Research square 2023; doi:10.21203/rs.3.rs-2762003/v1.
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Role of descemet's stripping without keratoplasty in management of endothelial disease.
Northey LC, Moloney G
Current opinion in ophthalmology 2023; (34(4)):348-353 doi:10.1097/ICU.0000000000000963.
PMID: 37254864 - 62
Influence of Subclinical Corneal Edema on Contrast Sensitivity in Fuchs Endothelial Corneal Dystrophy.
Friedrich M, Hofmann CA, Chychko L, et al.
Cornea 2024; (43(9)):1154-1161 doi:10.1097/ICO.0000000000003414.
PMID: 37889563 - 63
Prevalence and Economic Burden of Fuchs Endothelial Corneal Dystrophy in the Medicare Population in the United States.
Singh RB, Parmar UPS, Kahale F, et al.
Cornea 2024; (43(8)):1022-1027 doi:10.1097/ICO.0000000000003416.
PMID: 37906001 - 64
Descemet membrane endothelial keratoplasty compared with ultrathin Descemet stripping automated endothelial keratoplasty: a meta-analysis.
Sela TC, Iflah M, Muhsen K, Zahavi A
BMJ open ophthalmology 2023; (8(1)) doi:10.1136/bmjophth-2023-001397.
PMID: 37914389 - 65
Descemet Stripping Only: Long-Term Outcomes.
Hakim FE, Nagra AK, Dhaliwal DK
Cornea 2024; (43(8)):994-998 doi:10.1097/ICO.0000000000003421.
PMID: 37921677 - 66
Assessing Fuchs Corneal Endothelial Dystrophy Using Artificial Intelligence-Derived Morphometric Parameters From Specular Microscopy Images.
Prada AM, Quintero F, Mendoza K, et al.
Cornea 2024; (43(9)):1080-1087 doi:10.1097/ICO.0000000000003460.
PMID: 38334475 - 67
Predicting Long-Term Endothelial Cell Loss after Preloaded Descemet Membrane Endothelial Keratoplasty in Fuchs' Endothelial Corneal Dystrophy: A Mathematical Model.
Viola P, Neri E, Occhipinti T, et al.
Journal of clinical medicine 2024; (13(3)) doi:10.3390/jcm13030877.
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Fuchs endothelial corneal dystrophy: an updated review.
Altamirano F, Ortiz-Morales G, O'Connor-Cordova MA, et al.
International ophthalmology 2024; (44(1)):61 doi:10.1007/s10792-024-02994-1.
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In vivo confocal microscopy findings after Descemet stripping only with and without topical ripasudil supplementation in Fuchs endothelial dystrophy.
Northey LC, Oliver C, Trinh T, et al.
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 2024; (59(6)):e682-e690 doi:10.1016/j.jcjo.2024.02.016.
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Therapeutic future of Fuchs endothelial corneal dystrophy: An ongoing way to explore.
Liu JX, Chiang TL, Hung KF, Sun YC
Taiwan journal of ophthalmology 2024; (14(1)):15-26 doi:10.4103/tjo.TJO-D-23-00115.
PMID: 38654984 - 71
[Modern techniques and features of selective keratoplasty].
Yusef YN, Osipyan GA, Fisenko NV, Dzamikhova AK
Vestnik oftalmologii 2024; (140(2. Vyp. 2)):150-157 doi:10.17116/oftalma2024140022150.
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Diurnal changes of corneal epithelial and stromal thickness maps and visual quality in mild form of Fuchs' endothelial corneal dystrophy.
Krolo I, Bećirević AK, Radman I, et al.
Indian journal of ophthalmology 2025; (73(1)):122-127 doi:10.4103/IJO.IJO_282_24.
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Ten-year outcomes after DMEK, DSAEK, and PK: insights on graft survival, endothelial cell density loss, rejection and visual acuity.
Wilhelm TI, Gauché L, Böhringer D, et al.
Scientific reports 2025; (15(1)):1249 doi:10.1038/s41598-025-85138-4.
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Genetic and Demographic Determinants of Fuchs Endothelial Corneal Dystrophy Risk and Severity.
Liu S, Sadan AN, Bhattacharyya N, et al.
JAMA ophthalmology 2025; (143(4)):338-347 doi:10.1001/jamaophthalmol.2025.0109.
PMID: 40079965 - 75
Review of the Literature: Surgery Indications for Fuchs' Endothelial Corneal Dystrophy.
Tourabaly M, Knoeri J, Georgeon C, Borderie V
Journal of clinical medicine 2025; (14(7)) doi:10.3390/jcm14072365.
PMID: 40217815 - 76
Fellow Eye Comparison of Tomographic Parameters and Higher-Order Aberrations in Ultrathin Descemet Stripping Automated Endothelial Keratoplasty and Descemet Membrane Endothelial Keratoplasty.
Berger T, Seitz B, Suffo S, et al.
Klinische Monatsblatter fur Augenheilkunde 2026; (243(2)):139-145 doi:10.1055/a-2558-2583.
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One year follow up of descemet stripping only: corneal tomography changes and visual acuity outcomes.
Cuadrado AV, Sánchez-Ventosa Á, González-Cruces T, et al.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2025; (263(9)):2593-2608 doi:10.1007/s00417-025-06747-3.
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Delphi-Based Global Consensus on Fuchs Endothelial Corneal Dystrophy. An Endothelial Keratoplasty Learners Group Initiative.
Patel SV, Gupta N, Bhogal M, et al.
American journal of ophthalmology 2025; (280()):130-143 doi:10.1016/j.ajo.2025.08.012.
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10-Year outcome of descemet stripping only in a patient with Fuchs endothelial dystrophy: a case report.
Moayed F, Steindor FA, Armeni ZE, et al.
Therapeutic advances in ophthalmology 2025; (17()):25158414251359583 doi:10.1177/25158414251359583.
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Microbial keratitis in the age of resistance: unlocking the therapeutic potential of phage therapy.
Ibrahim R, Kumar P, Aranjani JM
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2025; (263(12)):3287-3299 doi:10.1007/s00417-025-06961-z.
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Sterile Corneal Infiltrate: A Difficult Dilemma.
Cheraqpour K
Ocular immunology and inflammation 2025; (33(10)):2510-2517 doi:10.1080/09273948.2025.2580346.
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Diurnal Variation in Corneal Stromal and Epithelial Thickness in Fuchs Endothelial Corneal Dystrophy: With and Without Intensified Hypertonic Saline Eyedrop Application.
Cieplucha M, Menzel-Severing J, Steindor F, et al.
Cornea 2026; (45(11)):1385-1391 doi:10.1097/ICO.0000000000004041.
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Corneal transplantation triple procedures.
Nair S, Deshmukh R, Mohan S, et al.
Survey of ophthalmology 2026; (71(3)):909-924 doi:10.1016/j.survophthal.2025.12.006.
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Beyond keratoplasty: The role of Descemet stripping only in the management of Fuchs endothelial dystrophy-a systematic review and meta-analysis.
Sahin Vural G, Akgun Z, Barut Selver O
Survey of ophthalmology 2026; (71(5)):1468-1477 doi:10.1016/j.survophthal.2026.03.010.
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Injectable corneal endothelial cell therapy: recent progress, translational barriers, and future directions.
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Frontiers in ophthalmology 2026; (6()):1799892 doi:10.3389/fopht.2026.1799892.
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Descemet Stripping Only in Fuchs Endothelial Corneal Dystrophy: Results of a Randomized Clinical Trial of Topical Ripasudil and Directions for Future Innovation.
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American journal of ophthalmology 2026; (290()):145-160 doi:10.1016/j.ajo.2026.06.014.
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Soft-shell phacoemulsification in Fuchs' endothelial dystrophy: Central corneal thickness as a predictor of post-operative keratoplasty.
Teh BL, Tzoumas N, Boso ALM, et al.
European journal of ophthalmology 2026; 11206721261445518 doi:10.1177/11206721261445518.
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Association between subjective symptoms and severity in patients with Fuchs endothelial corneal dystrophy.
Koizumi Y, Oie Y, Maeno S, et al.
Japanese journal of ophthalmology 2026; (70(5)):1066-1072 doi:10.1007/s10384-026-01391-8.
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Genome-Wide Association Study of Corneal Dystrophy Uncovers Novel Risk Loci and Enables Improved Polygenic Prediction of Fuchs Endothelial Corneal Dystrophy.
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Comparative Outcomes From 969 Endothelial Keratoplasties.
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