Research & Literature

Use of ultrasound for diagnosis and monitoring of outcomes in crystal arthropathies.

Grassi W, Okano T, Filippucci E

Current opinion in rheumatology 2015; (27(2)):147-55 doi:10.1097/BOR.0000000000000142.

The gouty tophus: a review.

Chhana A, Dalbeth N

Current rheumatology reports 2015; (17(3)):19 doi:10.1007/s11926-014-0492-x.

Application of a Novel Diagnostic Rule in the Differential Diagnosis between Acute Gouty Arthritis and Septic Arthritis.

Lee KH, Choi ST, Lee SK, et al.

Journal of Korean medical science 2015; (30(6)):700-4 doi:10.3346/jkms.2015.30.6.700.

Allopurinol hypersensitivity: investigating the cause and minimizing the risk.

Stamp LK, Day RO, Yun J

Nature reviews. Rheumatology 2016; (12(4)):235-42 doi:10.1038/nrrheum.2015.132.

Treatment of tophaceous gout: When medication is not enough.

Kasper IR, Juriga MD, Giurini JM, Shmerling RH

Seminars in arthritis and rheumatism 2016; (45(6)):669-74.

Dual-Energy Computed Tomography of the Knee, Ankle, and Foot: Noninvasive Diagnosis of Gout and Quantification of Monosodium Urate in Tendons and Ligaments.

Fritz J, Henes JC, Fuld MK, et al.

Seminars in musculoskeletal radiology 2016; (20(1)):130-6 doi:10.1055/s-0036-1579709.

Urate Handling in the Human Body.

Hyndman D, Liu S, Miner JN

Current rheumatology reports 2016; (18(6)):34 doi:10.1007/s11926-016-0587-7.

Genetic background of uric acid metabolism in a patient with severe chronic tophaceous gout.

Petru L, Pavelcova K, Sebesta I, Stiburkova B

Clinica chimica acta; international journal of clinical chemistry 2016; (460()):46-9.

2016 updated EULAR evidence-based recommendations for the management of gout.

Richette P, Doherty M, Pascual E, et al.

Annals of the rheumatic diseases 2017; (76(1)):29-42 doi:10.1136/annrheumdis-2016-209707.

Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney.

Miner JN, Tan PK, Hyndman D, et al.

Arthritis research & therapy 2016; (18(1)):214 doi:10.1186/s13075-016-1107-x.

Management of Gout: A Systematic Review in Support of an American College of Physicians Clinical Practice Guideline.

Shekelle PG, Newberry SJ, FitzGerald JD, et al.

Annals of internal medicine 2017; (166(1)):37-51 doi:10.7326/M16-0461.

Diagnosis of Acute Gout: A Clinical Practice Guideline From the American College of Physicians.

Qaseem A, McLean RM, Starkey M, et al.

Annals of internal medicine 2017; (166(1)):52-57 doi:10.7326/M16-0569.

Limitations of the Current Standards of Care for Treating Gout and Crystal Deposition in the Primary Care Setting: A Review.

Keenan RT

Clinical therapeutics 2017; (39(2)):430-441 doi:10.1016/j.clinthera.2016.12.011.

Crystal arthritides - gout and calcium pyrophosphate arthritis : Part 2: clinical features, diagnosis and differential diagnostics.

Schlee S, Bollheimer LC, Bertsch T, et al.

Zeitschrift fur Gerontologie und Geriatrie 2018; (51(5)):579-584 doi:10.1007/s00391-017-1198-2.

Value of ultrasonography in the diagnosis of gout in patients presenting with acute arthritis.

Pattamapaspong N, Vuthiwong W, Kanthawang T, Louthrenoo W

Skeletal radiology 2017; (46(6)):759-767 doi:10.1007/s00256-017-2611-z.

Molecular Pathophysiology of Gout.

Desai J, Steiger S, Anders HJ

Trends in molecular medicine 2017; (23(8)):756-768 doi:10.1016/j.molmed.2017.06.005.

Peripheral Bacterial Septic Arthritis: Review of Diagnosis and Management.

Hassan AS, Rao A, Manadan AM, Block JA

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 2017; (23(8)):435-442 doi:10.1097/RHU.0000000000000588.

Role of dual-energy CT in the diagnosis and follow-up of gout: systematic analysis of the literature.

Ramon A, Bohm-Sigrand A, Pottecher P, et al.

Clinical rheumatology 2018; (37(3)):587-595 doi:10.1007/s10067-017-3976-z.

Management of gout and hyperuricemia: Multidisciplinary consensus in Taiwan.

Yu KH, Chen DY, Chen JH, et al.

International journal of rheumatic diseases 2018; (21(4)):772-787 doi:10.1111/1756-185X.13266.

Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout.

White WB, Saag KG, Becker MA, et al.

The New England journal of medicine 2018; (378(13)):1200-1210 doi:10.1056/NEJMoa1710895.

A retrospective investigation of HLA-B*5801 in hyperuricemia patients in a Han population of China.

Cheng H, Yan D, Zuo X, et al.

Pharmacogenetics and genomics 2018; (28(5)):117-124 doi:10.1097/FPC.0000000000000334.

Retreatment with Pegloticase after a Gap in Therapy in Patients with Gout: A Report of Four Cases.

Morton AH, Hosey T, LaMoreaux B

Rheumatology and therapy 2018; (5(2)):583-594 doi:10.1007/s40744-018-0111-9.

An update on the genetics of hyperuricaemia and gout.

Major TJ, Dalbeth N, Stahl EA, Merriman TR

Nature reviews. Rheumatology 2018; (14(6)):341-353 doi:10.1038/s41584-018-0004-x.

Febuxostat for the treatment of hyperuricaemia in gout.

Robinson PC, Dalbeth N

Expert opinion on pharmacotherapy 2018; (19(11)):1289-1299 doi:10.1080/14656566.2018.1498842.

Evaluation of the diet wide contribution to serum urate levels: meta-analysis of population based cohorts.

Major TJ, Topless RK, Dalbeth N, Merriman TR

BMJ (Clinical research ed.) 2018; (363()):k3951 doi:10.1136/bmj.k3951.

How should we manage asymptomatic hyperuricemia?

Chalès G

Joint bone spine 2019; (86(4)):437-443 doi:10.1016/j.jbspin.2018.10.004.

Efficacy and cost-effectiveness of nurse-led care involving education and engagement of patients and a treat-to-target urate-lowering strategy versus usual care for gout: a randomised controlled trial.

Doherty M, Jenkins W, Richardson H, et al.

Lancet (London, England) 2018; (392(10156)):1403-1412 doi:10.1016/S0140-6736(18)32158-5.

Gout - An update of aetiology, genetics, co-morbidities and management.

Robinson PC

Maturitas 2018; (118()):67-73 doi:10.1016/j.maturitas.2018.10.012.

Efficacy of the HLA-B∗58:01 Screening Test in Preventing Allopurinol-Induced Severe Cutaneous Adverse Reactions in Patients with Chronic Renal Insufficiency-A Prospective Study.

Park HW, Kim DK, Kim SH, et al.

The journal of allergy and clinical immunology. In practice 2019; (7(4)):1271-1276 doi:10.1016/j.jaip.2018.12.012.

Allopurinol-Induced Stevens-Johnson Syndrome.

Gupta SS, Sabharwal N, Patti R, Kupfer Y

The American journal of the medical sciences 2019; (357(4)):348-351 doi:10.1016/j.amjms.2018.11.018.

Secretion of IL-1β From Monocytes in Gout Is Redox Independent.

Alberts BM, Bruce C, Basnayake K, et al.

Frontiers in immunology 2019; (10()):70 doi:10.3389/fimmu.2019.00070.

The anatomical pathology of gout: a systematic literature review.

Towiwat P, Chhana A, Dalbeth N

BMC musculoskeletal disorders 2019; (20(1)):140 doi:10.1186/s12891-019-2519-y.

Vegetarian diet and risk of gout in two separate prospective cohort studies.

Chiu THT, Liu CH, Chang CC, et al.

Clinical nutrition (Edinburgh, Scotland) 2020; (39(3)):837-844 doi:10.1016/j.clnu.2019.03.016.

Ulcerated tophaceous gout.

Ryan MP, Monjazeb S, Goodwin BP, Group AR

Dermatology online journal 2019; (25(3)).

2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout.

Richette P, Doherty M, Pascual E, et al.

Annals of the rheumatic diseases 2020; (79(1)):31-38 doi:10.1136/annrheumdis-2019-215315.

Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions of disease states of gout.

Bursill D, Taylor WJ, Terkeltaub R, et al.

Annals of the rheumatic diseases 2019; (78(11)):1592-1600 doi:10.1136/annrheumdis-2019-215933.

Bacterial Septic Arthritis of the Adult Native Knee Joint: A Review.

Elsissy JG, Liu JN, Wilton PJ, et al.

JBJS reviews 2020; (8(1)):e0059 doi:10.2106/JBJS.RVW.19.00059.

Pharmacologic Management of Gout in Patients with Cardiovascular Disease and Heart Failure.

Mouradjian MT, Plazak ME, Gale SE, et al.

American journal of cardiovascular drugs : drugs, devices, and other interventions 2020; (20(5)):431-445 doi:10.1007/s40256-020-00400-6.

Diagnostic value of ultrasound versus dual-energy computed tomography in patients with different stages of acute gouty arthritis.

Zhang B, Yang M, Wang H

Clinical rheumatology 2020; (39(5)):1649-1653 doi:10.1007/s10067-020-05014-6.

Allopurinol hypersensitivity: Pathogenesis and prevention.

Stamp LK, Chapman PT

Best practice & research. Clinical rheumatology 2020; (34(4)):101501 doi:10.1016/j.berh.2020.101501.

Cost-effectiveness of sequential urate lowering therapies for the management of gout in Singapore.

Pruis SL, Jeon YK, Pearce F, et al.

Journal of medical economics 2020; (23(8)):838-847 doi:10.1080/13696998.2020.1757456.

2020 American College of Rheumatology Guideline for the Management of Gout.

FitzGerald JD, Dalbeth N, Mikuls T, et al.

Arthritis care & research 2020; (72(6)):744-760 doi:10.1002/acr.24180.

2020 recommendations from the French Society of Rheumatology for the management of gout: Urate-lowering therapy.

Pascart T, Latourte A, Flipo RM, et al.

Joint bone spine 2020; (87(5)):395-404 doi:10.1016/j.jbspin.2020.05.002.

Global epidemiology of gout: prevalence, incidence, treatment patterns and risk factors.

Dehlin M, Jacobsson L, Roddy E

Nature reviews. Rheumatology 2020; (16(7)):380-390 doi:10.1038/s41584-020-0441-1.

The biology of urate.

Keenan RT

Seminars in arthritis and rheumatism 2020; (50(3S)):S2-S10 doi:10.1016/j.semarthrit.2020.04.007.

Pegloticase treatment of chronic refractory gout: Update on efficacy and safety.

Schlesinger N, Lipsky PE

Seminars in arthritis and rheumatism 2020; (50(3S)):S31-S38 doi:10.1016/j.semarthrit.2020.04.011.

The Epidemiology and Outcomes of Septic Arthritis in the Maltese Islands: A Hospital-Based Retrospective Cohort Study.

Vassallo C, Borg AA, Farrugia D, Mercieca C

Mediterranean journal of rheumatology 2020; (31(2)):195-205 doi:10.31138/mjr.31.2.195.

Gout: Rapid Evidence Review.

Clebak KT, Morrison A, Croad JR

American family physician 2020; (102(9)):533-538.

Long-term cardiovascular safety of febuxostat compared with allopurinol in patients with gout (FAST): a multicentre, prospective, randomised, open-label, non-inferiority trial.

Mackenzie IS, Ford I, Nuki G, et al.

Lancet (London, England) 2020; (396(10264)):1745-1757 doi:10.1016/S0140-6736(20)32234-0.

Pathophysiology of Gout.

Narang RK, Dalbeth N

Seminars in nephrology 2020; (40(6)):550-563 doi:10.1016/j.semnephrol.2020.12.001.

Autoinflammatory Features in Gouty Arthritis.

Galozzi P, Bindoli S, Doria A, et al.

Journal of clinical medicine 2021; (10(9)) doi:10.3390/jcm10091880.

Drug-induced liver injury associated with severe cutaneous adverse drug reactions: A nationwide study in Taiwan.

Huang YS, Wu CY, Chang TT, et al.

Liver international : official journal of the International Association for the Study of the Liver 2021; (41(11)):2671-2680 doi:10.1111/liv.14990.

Dietary and Lifestyle-Centered Approach in Gout Care and Prevention.

Yokose C, McCormick N, Choi HK

Current rheumatology reports 2021; (23(7)):51 doi:10.1007/s11926-021-01020-y.

Where Epigenetics Meets Food Intake: Their Interaction in the Development/Severity of Gout and Therapeutic Perspectives.

Georgel PT, Georgel P

Frontiers in immunology 2021; (12()):752359 doi:10.3389/fimmu.2021.752359.

Septic Arthritis: Diagnosis and Treatment.

Earwood JS, Walker TR, Sue GJC

American family physician 2021; (104(6)):589-597.

Association of acidic urine pH with impaired renal function in primary gout patients: a Chinese population-based cross-sectional study.

He Y, Xue X, Terkeltaub R, et al.

Arthritis research & therapy 2022; (24(1)):32 doi:10.1186/s13075-022-02725-w.

Comparative Effectiveness of Allopurinol and Febuxostat in Gout Management.

O'Dell JR, Brophy MT, Pillinger MH, et al.

NEJM evidence 2022; (1(3)) doi:10.1056/evidoa2100028.

Lowering and Raising Serum Urate Levels: Off-Label Effects of Commonly Used Medications.

Leung N, Yip K, Pillinger MH, Toprover M

Mayo Clinic proceedings 2022; (97(7)):1345-1362 doi:10.1016/j.mayocp.2022.02.027.

Dutch pharmacogenetics working group guideline for the gene-drug interaction of ABCG2, HLA-B and Allopurinol, and MTHFR, folic acid and methotrexate.

van der Pol KH, Nijenhuis M, Soree B, et al.

European journal of human genetics : EJHG 2024; (32(2)):155-162 doi:10.1038/s41431-022-01180-0.

Performance of a diagnostic score for gouty arthritis: results from a cohort of acute arthritis suspected of being septic.

Lafforgue A, Lambert C, Dubost JJ, et al.

Rheumatology international 2023; (43(1)):119-124 doi:10.1007/s00296-022-05216-y.

Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms. Part I. Epidemiology, pathogenesis, clinicopathological features, and prognosis.

Wei BM, Fox LP, Kaffenberger BH, et al.

Journal of the American Academy of Dermatology 2024; (90(5)):885-908 doi:10.1016/j.jaad.2023.02.072.

Management of Patients with Gout and Kidney Disease: A Review of Available Therapies and Common Missteps.

Kannuthurai V, Gaffo A

Kidney360 2023; (4(9)):e1332-e1340 doi:10.34067/KID.0000000000000221.

Tophaceous spinal gout in a young man with complete spinal cord injury.

Okoroafor F, Ghazali S, Bhattacharyya D

BMJ case reports 2023; (16(8)) doi:10.1136/bcr-2023-256360.

Effects of alcohol on the symptoms of gouty arthritis and taxonomic structure of gut microbiota in C57BL/6 mice.

Feng Y, Sun H, Zhu R, et al.

Frontiers in microbiology 2023; (14()):1257701 doi:10.3389/fmicb.2023.1257701.

Gouty tenosynovitis with compartment syndrome in the hand: A case report.

Lee DY, Eo S, Lim S, Yoon JS

World journal of clinical cases 2023; (11(30)):7492-7496 doi:10.12998/wjcc.v11.i30.7492.

Limb salvage and systemic management of gouty tophi: Case series.

Jiang X, Li A, Hao W, et al.

Medicine 2024; (103(20)):e38137 doi:10.1097/MD.0000000000038137.

Predicting Septic Arthritis in the Setting of Crystalline Arthropathy in the Native Joint Using Laboratory Data.

Skalitzky MK, Henrichsen JL, Noiseux NO

The Iowa orthopaedic journal 2024; (44(1)):69-72.

The comprehensive role of dual-energy CT in gout as an advanced diagnostic innovation.

Fukuda T, Subramanian M, Noda K, et al.

Skeletal radiology 2025; (54(11)):2253-2263 doi:10.1007/s00256-024-04856-4.

Associations of the ALDH2 rs671 polymorphism and alcohol intake with early-onset gout in a Chinese male cohort.

Hu S, Dalbeth N, Li Z, et al.

Joint bone spine 2025; (92(4)):105876 doi:10.1016/j.jbspin.2025.105876.

Gout.

FitzGerald JD

Annals of internal medicine 2025; (178(3)):ITC33-ITC48 doi:10.7326/ANNALS-24-03951.

Genetic background of selected hyperuricemia causing gout with pediatric onset.

Stiburkova B, Ichida K

Joint bone spine 2025; (92(4)):105884 doi:10.1016/j.jbspin.2025.105884.

The genetics of gout: translation into clinical practice.

Merriman TR, Rosas-Chavez F, Stamp LK

Therapeutic advances in musculoskeletal disease 2025; (17()):1759720X251366360 doi:10.1177/1759720X251366360.

Gout therapy updated.

McCarty KL, Gaffo AL, Diaz-Torne C

Therapeutic advances in musculoskeletal disease 2025; (17()):1759720X251384584 doi:10.1177/1759720X251384584.

Chronic Tophaceous Gout Presenting With Severe Polyarticular Erosive Disease: A Case Report.

Ambrósio AR, Costa Cabral T, Gago L, et al.

Cureus 2026; (18(1)):e101502 doi:10.7759/cureus.101502.

Is Gout an Autoinflammatory Disease?

Schlesinger N, Kaufmann D

Current rheumatology reports 2026; (28(1)).

[Gout of the manubriosternal joints: A case report].

Gan D, Fu Q, Tang X, et al.

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 2026; (58(3)):670-673.

Unilateral biportal endoscopic decompression for thoracic intraspinal gout with ossified ligamentum flavum: a case report and literature review.

Zhong F, Huang C, Feng X, et al.

Frontiers in surgery 2026; (13()):1831917 doi:10.3389/fsurg.2026.1831917.