Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
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Children's Hospital of Philadelphia
Philadelphia, United States
Boston Children's Hospital
Boston, United States
Cincinnati Children's Hospital Medical Center
Cincinnati, United States
Deutsches Herzzentrum München
Munich, Germany
University of Florida
Gainesville, United States
University of Michigan
Ann Arbor, United States
Baylor College of Medicine
Houston, United States
Emory University
Atlanta, United States
University of Toronto
Toronto, Canada
Nationwide Children's Hospital
Columbus, United States
References
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Cognitive Development of School-Age Hypoplastic Left Heart Syndrome Survivors: A Single Center Study.
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Parenting a child at home with hypoplastic left heart syndrome: experiences of commitment, of stress, and of love.
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Protein-Losing Enteropathy in Patients With Congenital Heart Disease.
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Effectiveness of interstage home monitoring on healthcare outcomes in infants with hypoplastic left heart syndrome: a systematic review protocol.
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Grief and coping of parents whose child has a constant life-threatening disability, hypoplastic left heart syndrome with reference to the Dual-Process Model.
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Death studies 2018; (42(9)):569-578 doi:10.1080/07481187.2017.1407380.
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Resource and cost considerations in treating hypoplastic left heart syndrome.
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Pediatric health, medicine and therapeutics 2016; (7()):149-153 doi:10.2147/PHMT.S98327.
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Surgical Palliation for Hypoplastic Left Heart Syndrome: For Now, Just Keep Doing What You Do Best.
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High risk HLHS: hybrid approach yes, but how does it work?
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A novel, data-driven conceptualization for critical left heart obstruction.
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Prostaglandin E1 overdose in a term neonate with congenital heart disease.
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Protein-Losing Enteropathy and Plastic Bronchitis After the Fontan Operation.
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The impact of morphological characteristics on late outcomes in patients born with hypoplastic left heart syndrome†.
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On rough road of hypoplastic left heart syndrome after Norwood procedure.
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A Novel Case of Marfan Syndrome in an Infant With Hypoplastic Left Heart Syndrome.
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Behavior and Quality of Life at 6 Years for Children With Hypoplastic Left Heart Syndrome.
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Evolution of the Norwood operation outcomes in patients with late presentation.
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Provider perspective on the role of palliative care in hypoplastic left heart syndrome.
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Recurrent Pulmonary Artery Interventions Following the Norwood Procedure Are Not Associated With Conduit Type.
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The impact of prenatal counselling on mothers of surviving children with hypoplastic left heart syndrome: A qualitative interview study.
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Commentary: Lymphatic fluid flows uphill in both hemispheres-and leaks in the same places.
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Protein-losing enteropathy and plastic bronchitis after the Fontan procedure.
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Diagnosis and Management of Lymphatic Disorders in Congenital Heart Disease.
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Low-dose prostaglandin E1 is safe and effective for critical congenital heart disease: is it time to revisit the dosing guidelines?
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Attrition between the superior cavopulmonary connection and the Fontan procedure in hypoplastic left heart syndrome.
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Hybridizing the hybrid: a "serendipitous bridge" to heart transplantation in a child with hypoplastic left heart syndrome.
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A milestone in congenital cardiac surgery: Four decades of the Norwood procedure.
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Journal of cardiac surgery 2021; (36(8)):2919-2923 doi:10.1111/jocs.15657.
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Comparison of shunt types in the neonatal Norwood procedure for single ventricle.
Ono M, Kido T, Wallner M, et al.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2021; (60(5)):1084-1091 doi:10.1093/ejcts/ezab163.
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Radiofrequency catheter ablation as a treatment option in a patient with hypoplastic left heart syndrome and atrial flutter after Fontan operation-Case report.
Jagosz M, Kowalska W, Lenarczyk R, et al.
Journal of arrhythmia 2021; (37(4)):1101-1104 doi:10.1002/joa3.12579.
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Valvuloplasty in 103 fetuses with critical aortic stenosis: outcome and new predictors for postnatal circulation.
Tulzer A, Arzt W, Gitter R, et al.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2022; (59(5)):633-641 doi:10.1002/uog.24792.
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Caring for a Child with Hypoplastic Left Heart Syndrome: Parent and Medical Perspective.
Nicholas B, Nicholas C, Allen RL, Cua CL
Cardiology and therapy 2022; (11(1)):9-12 doi:10.1007/s40119-021-00246-2.
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Influence of Shunt Type on Survival and Right Heart Function after the Norwood Procedure for Aortic Atresia.
Piber N, Ono M, Palm J, et al.
Seminars in thoracic and cardiovascular surgery 2022; (34(4)):1300-1310 doi:10.1053/j.semtcvs.2021.11.012.
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A Comprehensive Approach to the Management of Patients With HLHS and Related Malformations: An Analysis of 83 Patients (2015-2021).
Bleiweis MS, Peek GJ, Philip J, et al.
World journal for pediatric & congenital heart surgery 2022; (13(5)):664-675 doi:10.1177/21501351221088030.
PMID: 35511494 - 60
Flow-Mediated Factors in the Pathogenesis of Hypoplastic Left Heart Syndrome.
Rahman A, Chaturvedi RR, Sled JG
Journal of cardiovascular development and disease 2022; (9(5)) doi:10.3390/jcdd9050154.
PMID: 35621865 - 61
Utilizing technology to expand home monitoring to high-risk infants with CHD.
Hartman D, Ebenroth E, Farrell A
Cardiology in the young 2023; (33(7)):1124-1128 doi:10.1017/S1047951122002232.
PMID: 35836381 - 62
Hypoplastic Left Ventricle: Hypoplastic Left Heart Complex.
Tchervenkov CI, Tang R, Jacobs JP
World journal for pediatric & congenital heart surgery 2022; (13(5)):631-636 doi:10.1177/21501351221116016.
PMID: 36053097 - 63
Technical Aspects and Common Pitfalls of Norwood With Modified Blalock Taussig Shunt.
Juaneda I, Chiostri B, Kreutzer C
World journal for pediatric & congenital heart surgery 2022; (13(5)):576-580 doi:10.1177/21501351221111798.
PMID: 36053104 - 64
Hypoplastic Left Heart Syndrome: Definition, Morphology, and Classification.
Jacobs JP
World journal for pediatric & congenital heart surgery 2022; (13(5)):559-564 doi:10.1177/21501351221114770.
PMID: 36053108 - 65
Modeling of the Tricuspid Valve and Right Ventricle in Hypoplastic Left Heart Syndrome With a Fontan Circulation.
Nam HH, Flynn M, Lasso A, et al.
Circulation. Cardiovascular imaging 2023; (16(3)):e014671 doi:10.1161/CIRCIMAGING.122.014671.
PMID: 36866669 - 66
The Impact of Prenatal Diagnosis in the Evolution of Newborns with Congenital Heart Disease.
Toma D, Moldovan E, Gozar L
Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) 2023; (9(1)):6-11 doi:10.2478/jccm-2023-0007.
PMID: 36890976 - 67
Experiences of parents of children with hypoplastic left heart syndrome during their treatment: a qualitative study.
Silberberg A, Castro Méndez J, Torres SF, et al.
Cardiology in the young 2023; (33(12)):2553-2558 doi:10.1017/S1047951123000677.
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Attributable mortality benefit of digoxin treatment in hypoplastic left heart syndrome after the Norwood operation: An instrumental variable-based analysis using data from the Pediatric Health Information Systems Database.
O'Byrne ML, Song L, Huang J, et al.
American heart journal 2023; (263()):35-45 doi:10.1016/j.ahj.2023.05.005.
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Treatment of hypoplastic left heart syndrome: a systematic review and meta-analysis of randomised controlled trials.
Kim AY, Woo W, Saxena A, et al.
Cardiology in the young 2024; (34(3)):659-666 doi:10.1017/S1047951123002986.
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Impact of home monitoring program on interstage mortality after the Norwood procedure.
Staehler H, Schaeffer T, Wasner J, et al.
Frontiers in cardiovascular medicine 2023; (10()):1239477 doi:10.3389/fcvm.2023.1239477.
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Long-term outcomes of hypoplastic left heart syndrome with analysis of the Norwood procedure in infants following bilateral pulmonary artery banding.
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JTCVS open 2023; (16()):675-688 doi:10.1016/j.xjon.2023.07.023.
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Hypoplastic Left Heart Syndrome: A Case Report.
Manandhar SR, Ghimire A, Rai D, et al.
JNMA; journal of the Nepal Medical Association 2023; (61(264)):665-667 doi:10.31729/jnma.8243.
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Mitotic Block and Epigenetic Repression Underlie Neurodevelopmental Defects and Neurobehavioral Deficits in Congenital Heart Disease.
Gabriel GC, Yagi H, Tan T, et al.
bioRxiv : the preprint server for biology 2024; doi:10.1101/2023.11.05.565716.
PMID: 38464057 - 74
Catheter-Based Fetal Cardiac Interventions.
Yilmaz Furtun B, Morris SA
Journal of cardiovascular development and disease 2024; (11(6)) doi:10.3390/jcdd11060167.
PMID: 38921667 - 75
Long-term survival in patients with univentricular heart: A nationwide, register-based cohort study.
Öztürk AG, Dellborg M, Damlin A, et al.
International journal of cardiology. Congenital heart disease 2024; (15()):100503 doi:10.1016/j.ijcchd.2024.100503.
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Unusual presentation of anomalous origin of the right pulmonary artery from the ascending aorta: case report.
Elhudairy M, Alkhushi N, Al-Radi O, et al.
The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology 2025; (77(1)):20 doi:10.1186/s43044-025-00614-6.
PMID: 39903373 - 77
Single ventricle infants: outcomes and impact of home monitoring programme enrolment.
Scott AE, Johnson MJ, Bharucha T, Marino LV
Cardiology in the young 2025; 1-7 doi:10.1017/S1047951124036345.
PMID: 39935031 - 78
Navigating family life with Hypoplastic Left Heart Syndrome: A qualitative study.
Green MD, Prevost-Reilly A, Parker DM, Carpenter-Song E
PLOS mental health 2024; (1(7)) doi:10.1371/journal.pmen.0000208.
PMID: 40575012 - 79
Hypoplastic left heart syndrome with mitral regurgitation: a new marker of poor fetal outcome.
Witkowski S, Respondek-Liberska M, Strzelecka I
Journal of ultrasonography 2025; (25(100)):20250009 doi:10.15557/jou.2025.0009.
PMID: 40656547 - 80
Multimodal Imaging from Fetal to Adult Life: A Comprehensive Approach to Hypoplastic Left Heart Syndrome (HLHS).
Moscatelli S, Sabatino J, Leo I, et al.
Journal of cardiovascular development and disease 2025; (12(9)) doi:10.3390/jcdd12090349.
PMID: 41002628 - 81
Plastic Bronchitis: Extensive Cast Expectoration in a 6-Year-Old Boy with Fontan Circulation.
Pfeifer J, Poryo M, Fries P, Abdul-Khaliq H
Diagnostics (Basel, Switzerland) 2025; (15(22)) doi:10.3390/diagnostics15222864.
PMID: 41300888