Research & Literature

Tolerance and efficacy of off-label anti-interleukin-1 treatments in France: a nationwide survey.

Rossi-Semerano L, Fautrel B, Wendling D, et al.

Orphanet journal of rare diseases 2015; (10()):19 doi:10.1186/s13023-015-0228-7.

Multimodality imaging of pericardial disease.

Cremer PC, Kwon DH

Current cardiology reports 2015; (17(4)):24 doi:10.1007/s11886-015-0577-9.

Recurrent pericarditis: new and emerging therapeutic options.

Imazio M, Lazaros G, Brucato A, Gaita F

Nature reviews. Cardiology 2016; (13(2)):99-105 doi:10.1038/nrcardio.2015.115.

Recurrent Pericarditis: Modern Approach in 2016.

Imazio M, Adler Y, Charron P

Current cardiology reports 2016; (18(6)):50 doi:10.1007/s11886-016-0727-8.

Recurrent pericarditis in children and adolescents: a multicentre cohort study.

Imazio M, Brucato A, Pluymaekers N, et al.

Journal of cardiovascular medicine (Hagerstown, Md.) 2016; (17(9)):707-12 doi:10.2459/JCM.0000000000000300.

Recurrent Pericarditis.

Imazio M, Gribaudo E, Gaita F

Progress in cardiovascular diseases 2017; (59(4)):360-368 doi:10.1016/j.pcad.2016.10.001.

Effect of Anakinra on Recurrent Pericarditis Among Patients With Colchicine Resistance and Corticosteroid Dependence: The AIRTRIP Randomized Clinical Trial.

Brucato A, Imazio M, Gattorno M, et al.

JAMA 2016; (316(18)):1906-1912 doi:10.1001/jama.2016.15826.

Pathophysiology of the Pericardium.

Hoit BD

Progress in cardiovascular diseases 2017; (59(4)):341-348 doi:10.1016/j.pcad.2016.11.001.

Recurrent pericarditis.

Imazio M, Battaglia A, Gaido L, Gaita F

La Revue de medecine interne 2017; (38(5)):307-311 doi:10.1016/j.revmed.2016.12.006.

Management of idiopathic recurrent pericarditis in adults and in children: a role for IL-1 receptor antagonism.

Brucato A, Emmi G, Cantarini L, et al.

Internal and emergency medicine 2018; (13(4)):475-489 doi:10.1007/s11739-018-1842-x.

Anakinra for the treatment of rheumatoid arthritis: a safety evaluation.

Ramírez J, Cañete JD

Expert opinion on drug safety 2018; (17(7)):727-732 doi:10.1080/14740338.2018.1486819.

[Ten questions about constrictive pericarditis].

Imazio M

Giornale italiano di cardiologia (2006) 2018; (19(7)):412-419 doi:10.1714/2938.29537.

Anakinra as rescue therapy for steroid-dependent idiopathic recurrent pericarditis in children: case report and literature review.

Rodriguez-Gonzalez M, Ruiz-Gonzalez E, Castellano-Martinez A

Cardiology in the young 2019; (29(2)):241-243 doi:10.1017/S1047951118002020.

Contemporary diagnosis and treatment of recurrent pericarditis.

Andreis A, Imazio M, de Ferrari GM

Expert review of cardiovascular therapy 2019; (17(11)):817-826 doi:10.1080/14779072.2019.1691916.

Usefulness of Cardiac Magnetic Resonance for Recurrent Pericarditis.

Imazio M, Pivetta E, Palacio Restrepo S, et al.

The American journal of cardiology 2020; (125(1)):146-151 doi:10.1016/j.amjcard.2019.09.026.

Corticosteroids for Acute and Recurrent Idiopathic Pericarditis: Unexpected Evidences.

Perrone A, Castrovilli A, Piazzolla G, et al.

Cardiology research and practice 2019; (2019()):1348364 doi:10.1155/2019/1348364.

Multimodality imaging in patients with post-cardiac injury syndrome.

Verma BR, Chetrit M, Gentry Iii JL, et al.

Heart (British Cardiac Society) 2020; (106(9)):639-646 doi:10.1136/heartjnl-2019-316050.

Acute recurrent pericarditis: from pathophysiology towards new treatment strategy.

Cacoub P, Marques C

Heart (British Cardiac Society) 2020; (106(14)):1046-1051 doi:10.1136/heartjnl-2019-316481.

Anakinra in Recurrent Pericarditis: Current Evidence on Clinical Use, Effectiveness, and Safety.

Correia ETO, Dos Santos Barbetta LM, de Almeida JPCL, Mesquita ET

Journal of cardiovascular pharmacology 2020; (76(1)):42-49 doi:10.1097/FJC.0000000000000839.

Hydroxychloroquine for colchicine-resistant glucocorticoid-dependent idiopathic recurrent pericarditis: A pilot observational prospective study.

Lazaros G, Antonopoulos AS, Antonatou K, et al.

International journal of cardiology 2020; (311()):77-82 doi:10.1016/j.ijcard.2020.03.069.

The autoinflammatory side of recurrent pericarditis: Enlightening the pathogenesis for a more rational treatment.

Lopalco G, Rigante D, Cantarini L, et al.

Trends in cardiovascular medicine 2021; (31(5)):265-274 doi:10.1016/j.tcm.2020.04.006.

Cardiac tamponade: an educational review.

Imazio M, De Ferrari GM

European heart journal. Acute cardiovascular care 2021; (10(1)):102–109.

Phase 3 Trial of Interleukin-1 Trap Rilonacept in Recurrent Pericarditis.

Klein AL, Imazio M, Cremer P, et al.

The New England journal of medicine 2021; (384(1)):31-41 doi:10.1056/NEJMoa2027892.

Burden of Recurrent Pericarditis on Health-Related Quality of Life.

LeWinter M, Kontzias A, Lin D, et al.

The American journal of cardiology 2021; (141()):113-119 doi:10.1016/j.amjcard.2020.11.018.

An update on the pathophysiology of acute and recurrent pericarditis.

Bonaventura A, Vecchié A, Mauro AG, et al.

Panminerva medica 2021; (63(3)):249-260 doi:10.23736/S0031-0808.20.04205-6.

Recurrent pericarditis: an update on diagnosis and management.

Vecchiè A, Dell M, Mbualungu J, et al.

Panminerva medica 2021; (63(3)):261-269 doi:10.23736/S0031-0808.21.04210-5.

US Database Study of Clinical Burden and Unmet Need in Recurrent Pericarditis.

Klein A, Cremer P, Kontzias A, et al.

Journal of the American Heart Association 2021; (10(15)):e018950 doi:10.1161/JAHA.120.018950.

The Impact of Physical Activity on Pericarditis.

Grant JK, Shah NP

Current cardiology reports 2021; (23(10)):150 doi:10.1007/s11886-021-01578-0.

Rilonacept: A Newly Approved Treatment for Recurrent Pericarditis.

Schwier NC

The Annals of pharmacotherapy 2022; (56(5)):572-581 doi:10.1177/10600280211036499.

Anti-interleukin-1 agents for pericarditis: a primer for cardiologists.

Imazio M, Lazaros G, Gattorno M, et al.

European heart journal 2022; (43(31)):2946-2957 doi:10.1093/eurheartj/ehab452.

Pharmacologic treatment of acute and recurrent pericarditis: a systematic review and meta-analysis of controlled clinical trials.

Avondo S, Andreis A, Casula M, et al.

Panminerva medica 2021; (63(3)):314-323 doi:10.23736/S0031-0808.21.04263-4.

Effect of interleukin-1 blockade with anakinra on leukocyte count in patients with ST-segment elevation acute myocardial infarction.

Del Buono MG, Damonte JI, Trankle CR, et al.

Scientific reports 2022; (12(1)):1254 doi:10.1038/s41598-022-05374-w.

Advances in pharmacotherapy for acute and recurrent pericarditis.

Vecchié A, Del Buono MG, Mauro AG, et al.

Expert opinion on pharmacotherapy 2022; (23(6)):681-691 doi:10.1080/14656566.2022.2054327.

Pericarditis and Autoinflammation: A Clinical and Genetic Analysis of Patients With Idiopathic Recurrent Pericarditis and Monogenic Autoinflammatory Diseases at a National Referral Center.

Peet CJ, Rowczenio D, Omoyinmi E, et al.

Journal of the American Heart Association 2022; (11(11)):e024931 doi:10.1161/JAHA.121.024931.

Pericardial tamponade: A comprehensive emergency medicine and echocardiography review.

Alerhand S, Adrian RJ, Long B, Avila J

The American journal of emergency medicine 2022; (58()):159-174 doi:10.1016/j.ajem.2022.05.001.

Advances in Imaging and Targeted Therapies for Recurrent Pericarditis: A Review.

Kumar S, Khubber S, Reyaldeen R, et al.

JAMA cardiology 2022; (7(9)):975-985 doi:10.1001/jamacardio.2022.2584.

Interleukin-1 Trap Rilonacept Improved Health-Related Quality of Life and Sleep in Patients With Recurrent Pericarditis: Results From the Phase 3 Clinical Trial RHAPSODY.

Brucato A, Lim-Watson MZ, Klein A, et al.

Journal of the American Heart Association 2022; (11(20)):e023252 doi:10.1161/JAHA.121.023252.

Transition to rilonacept monotherapy from oral therapies in patients with recurrent pericarditis.

Brucato A, Wheeler A, Luis SA, et al.

Heart (British Cardiac Society) 2023; (109(4)):297-304 doi:10.1136/heartjnl-2022-321328.

New Developments in the Management of Recurrent Pericarditis.

Imazio M, Mardigyan V, Andreis A, et al.

The Canadian journal of cardiology 2023; (39(8)):1103-1110 doi:10.1016/j.cjca.2023.04.008.

Paradigm Shift in Diagnosis and Targeted Therapy in Recurrent Pericarditis.

Dong T, Klein AL, Wang TKM

Current cardiology reports 2023; (25(9)):993-1000 doi:10.1007/s11886-023-01912-8.

Cardiac tamponade.

Adler Y, Ristić AD, Imazio M, et al.

Nature reviews. Disease primers 2023; (9(1)):36 doi:10.1038/s41572-023-00446-1.

Comparison of Colchicine Monotherapy Versus Nonsteroidal Anti-Inflammatory Drugs Monotherapy or Combination Therapy for the Prevention of Recurrent Pericarditis in Patients With Heart Failure With Reduced Ejection Fraction and/or Coronary Artery Disease.

Musick K, Knoell C, Clarke MM

Journal of pharmacy practice 2024; (37(4)):900-905 doi:10.1177/08971900231196081.

Prevalence of Pericardial Late Gadolinium Enhancement in Patients After Cardiac Surgery: Clinical and Histological Correlations.

Pavon AG, Martinez Fernandez R, Arangalage D, et al.

Circulation. Cardiovascular imaging 2023; (16(11)):e015606 doi:10.1161/CIRCIMAGING.123.015606.

Novel Therapeutic Insights Into the Treatment of Pericarditis: Targeting the Innate Immune System.

Vecchié A, Bonaventura A, Golino M, et al.

Journal of cardiovascular pharmacology 2024; (83(5)):377-383 doi:10.1097/FJC.0000000000001553.

Pericarditis recurrence is associated with milder electrocardiographic, echocardiographic, and laboratory findings.

Weiss T, Itelman E, Lotan D, et al.

Internal and emergency medicine 2024; (19(4)):1035-1039 doi:10.1007/s11739-024-03579-7.

Serial cardiac magnetic resonance imaging for guidance of therapy management in patients treated with anakinra due to recurrent pericarditis.

Bianco F, Bucciarelli V, Coretti F, et al.

European heart journal. Imaging methods and practice 2024; (2(1)):qyae019 doi:10.1093/ehjimp/qyae019.

Longitudinal cardiac magnetic resonance imaging following clinical response to rilonacept and prior to recurrence upon treatment suspension: a RHAPSODY subgroup analysis.

Cremer PC, Brucato A, Insalaco A, et al.

European heart journal. Cardiovascular Imaging 2024; (26(1)):72-79 doi:10.1093/ehjci/jeae200.

Recurrent pericarditis and interleukin (IL)-1 inhibitors.

Principi N, Lazzara A, Paglialonga L, et al.

International immunopharmacology 2024; (141()):113017 doi:10.1016/j.intimp.2024.113017.

Diagnosis, Risk Stratification, and Treatment of Pericarditis: A Review.

Cremer PC, Klein AL, Imazio M

JAMA 2024; (332(13)):1090-1100 doi:10.1001/jama.2024.12935.

Recurrent pericarditis in older adults: Clinical and laboratory features and outcome.

Bizzi E, Cavaleri F, Mascolo R, et al.

Journal of the American Geriatrics Society 2024; (72(11)):3467-3475 doi:10.1111/jgs.19150.

Advances in the Multimodality Imaging and Management of Recurrent Pericarditis: A Contemporary Review.

Sanaka H, Haroun E, Arockiam AD, et al.

Current cardiology reports 2024; (26(12)):1359-1375 doi:10.1007/s11886-024-02133-3.

Old and New Biomarkers in Idiopathic Recurrent Acute Pericarditis (IRAP): Prognosis and Outcomes.

Mascolo R, Bizzi E, Martelli M, et al.

Current cardiology reports 2025; (27(1)):17.

Recurrent pericarditis with normal C-reactive protein: Clinical and laboratory features, biomarkers and outcome in a non-inflammatory phenotype.

Mascolo R, Wu MA, Berra S, et al.

European journal of internal medicine 2025; (135()):108-117 doi:10.1016/j.ejim.2025.03.011.

Current Drug Treatment for Acute and Recurrent Pericarditis.

Bonaventura A, Santagata D, Vecchié A, Abbate A

Drugs 2025; (85(5)):643-658 doi:10.1007/s40265-025-02169-x.

Rilonacept for Recurrent Postcardiac Injury Syndrome Pericarditis in a Young Hockey Player: When to Return to Exercise.

Massad F, Rosenzveig A, Reiss S, et al.

JACC. Case reports 2025; (30(31)):105326 doi:10.1016/j.jaccas.2025.105326.

Comparative analysis of recurrence rates following various cessation strategies for rilonacept in recurrent pericarditis.

Saraswati U, Bhalla JS, Tereshchenko LG, et al.

Heart (British Cardiac Society) 2026; (112(8)):454-461 doi:10.1136/heartjnl-2024-325515.

Familial Mediterranean Fever: A Diagnostic and Therapeutic Challenge.

Sia R

Cureus 2025; (17(12)):e98777 doi:10.7759/cureus.98777.

Myocarditis and pericarditis in focus: A critical appraisal of the 2025 ESC vs ACC position statements from the Italian society of cardiology working group on cardiomyopathies and pericardial diseases.

Imazio M, Collini V, Merlo M, et al.

Trends in cardiovascular medicine 2026; (36(5)):317-326 doi:10.1016/j.tcm.2026.01.002.

Drug-induced liver injury secondary to anakinra in a patient with systemic juvenile idiopathic arthritis-Case report and literature overview.

Mannala S, Kehar M, Samson L, et al.

Canadian liver journal 2025; (8(4)):591-596 doi:10.3138/canlivj-2025-0039.

French protocol for the diagnosis and management of recurrent pericarditis.

Jamilloux Y, André M, Maillard H, et al.

La Revue de medecine interne 2026; (47(3)):127-146 doi:10.1016/j.revmed.2026.02.002.

Relapsing Pericarditis: Prediction of Relapses, Risk Scores, and Role of Exercise Restriction.

El Roumi J, Ikram J, Kai Ming Wang T

Methodist DeBakey cardiovascular journal 2026; (22(2)):14-26 doi:10.14797/mdcvj.1777.

Pericarditis in Patients with Autoimmune Disease: Insights into Prevalence and Optimal Management.

Fakikh Y, Kazzaz S, Malahfji M

Methodist DeBakey cardiovascular journal 2026; (22(2)):50-59 doi:10.14797/mdcvj.1780.

Mechanistic Insights and Emerging Therapeutic Strategies in Recurrent Pericarditis.

Alqahtani MA, Wang TKM, Klein AL

Methodist DeBakey cardiovascular journal 2026; (22(2)):4-13 doi:10.14797/mdcvj.1760.

How to Use Multimodality Imaging for Pericarditis.

El Roumi J, Ikram J, Wang TKM, Klein AL

Circulation. Cardiovascular imaging 2026; (19(4)):e018544 doi:10.1161/CIRCIMAGING.125.018544.

ABCDE of complex pericarditis cases.

Marchetta M, Adamo L, Bonaventura A, et al.

Heart (British Cardiac Society) 2026; doi:10.1136/heartjnl-2026-328058.

Innate and Adaptive Immune Mechanisms in Pericarditis: Pathobiology and Clinical Implications.

Zhang C, Abada S, Tasca S, et al.

The Canadian journal of cardiology 2026; (42(8)):1872-1888 doi:10.1016/j.cjca.2026.04.017.

Updates on Pathophysiology of Pericarditis to Guide Development of Therapeutics.

Bonaventura A, Vecchié A, Mauro AG, et al.

Current cardiology reports 2026; (28(1)).

Recurrent Pericarditis in a Rugby Player: Imaging-Guided Therapy.

Abuawad A, Badwan O, Ehsan M, et al.

JACC. Case reports 2026; (31(28)):108804 doi:10.1016/j.jaccas.2026.108804.