Research & Literature

Excess iodide induces an acute inhibition of the sodium/iodide symporter in thyroid male rat cells by increasing reactive oxygen species.

Arriagada AA, Albornoz E, Opazo MC, et al.

Endocrinology 2015; (156(4)):1540-51 doi:10.1210/en.2014-1371.

Amiodarone and the thyroid.

Jabrocka-Hybel A, Bednarczuk T, Bartalena L, et al.

Endokrynologia Polska 2015; (66(2)):176-86 doi:10.5603/EP.2015.0025.

MCT8 is Downregulated by Short Time Iodine Overload in the Thyroid Gland of Rats.

de Souza ECL, Dias GRM, Cardoso RC, et al.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 2015; (47(12)):910-915 doi:10.1055/s-0035-1550008.

Iodide excess regulates its own efflux: a possible involvement of pendrin.

Calil-Silveira J, Serrano-Nascimento C, Kopp PA, Nunes MT

American journal of physiology. Cell physiology 2016; (310(7)):C576-82 doi:10.1152/ajpcell.00210.2015.

Intra-individual variation in urinary iodine concentration: effect of statistical correction on population distribution using seasonal three-consecutive-day spot urine in children.

Ji X, Liu P, Sun Z, et al.

BMJ open 2016; (6(2)):e010217 doi:10.1136/bmjopen-2015-010217.

Thyroid Dysfunction in Children Exposed to Iodinated Contrast Media.

Barr ML, Chiu HK, Li N, et al.

The Journal of clinical endocrinology and metabolism 2016; (101(6)):2366-70 doi:10.1210/jc.2016-1330.

Iodine Concentration in Breastmilk and Urine among Lactating Women of Bhaktapur, Nepal.

Henjum S, Kjellevold M, Ulak M, et al.

Nutrients 2016; (8(5)).

[Iodine excess induced thyroid dysfunction].

Egloff M, Philippe J

Revue medicale suisse 2016; (12(515)):804-9.

Urinary iodine, thyroid function, and thyroglobulin as biomarkers of iodine status.

Pearce EN, Caldwell KL

The American journal of clinical nutrition 2016; (104 Suppl 3()):898S-901S doi:10.3945/ajcn.115.110395.

Effect of excess iodine intake on thyroid on human health.

Koukkou EG, Roupas ND, Markou KB

Minerva medica 2017; (108(2)):136-146 doi:10.23736/S0026-4806.17.04923-0.

[Amiodarone-induced thyrotoxicosis].

Bogazzi F, Tomisti L, Di Bello V, Martino E

Giornale italiano di cardiologia (2006) 2017; (18(3)):219-229 doi:10.1714/2674.27399.

Screening of congenital hypothyroidism in preterm, low birth weight and very low birth weight neonates: A systematic review.

Hashemipour M, Hovsepian S, Ansari A, et al.

Pediatrics and neonatology 2018; (59(1)):3-14 doi:10.1016/j.pedneo.2017.04.006.

Elemental analysis of the thyroid by laser induced breakdown spectroscopy.

Ahmed I, Ahmed R, Yang J, et al.

Biomedical optics express 2017; (8(11)):4865-4871 doi:10.1364/BOE.8.004865.

Lymphocutaneous Sporotrichosis Treated with Potassium Iodide with Development of Subclinical Hypothyroidism: Wolff-Chaikoff Effect?

Arora P, Raihan M, Kubba A, Gautam RK

Indian dermatology online journal 2017; (8(6)):475-477 doi:10.4103/idoj.IDOJ_3_17.

Amiodarone-Induced Thyroid Dysfunction: A Clinical Update.

Elnaggar MN, Jbeili K, Nik-Hussin N, et al.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2018; (126(6)):333-341 doi:10.1055/a-0577-7574.

2018 European Thyroid Association (ETA) Guidelines for the Management of Amiodarone-Associated Thyroid Dysfunction.

Bartalena L, Bogazzi F, Chiovato L, et al.

European thyroid journal 2018; (7(2)):55-66 doi:10.1159/000486957.

Maternal iodine excess: an uncommon cause of acquired neonatal hypothyroidism.

Hamby T, Kunnel N, Dallas JS, Wilson DP

Journal of pediatric endocrinology & metabolism : JPEM 2018; (31(9)):1061-1064 doi:10.1515/jpem-2018-0138.

The catalytic role of iodine excess in loss of homeostasis in autoimmune thyroiditis.

Duntas LH

Current opinion in endocrinology, diabetes, and obesity 2018; (25(5)):347-352 doi:10.1097/MED.0000000000000425.

Iodine-induced hypothyroidism in a girl with anorexia nervosa.

Kita Y, Mori J, Hosoi H

Pediatrics international : official journal of the Japan Pediatric Society 2019; (61(5)):528-529 doi:10.1111/ped.13846.

The Effects of Amiodarone on Thyroid Function in Pediatric and Young Adult Patients.

Barrett B, Hawkes CP, Isaza A, Bauer AJ

The Journal of clinical endocrinology and metabolism 2019; (104(11)):5540-5546 doi:10.1210/jc.2019-00990.

How can the occurrence of delayed elevation of thyroid stimulating hormone in preterm infants born between 35 and 36 weeks gestation be predicted?

Heo YJ, Lee YA, Lee B, et al.

PloS one 2019; (14(8)):e0220240 doi:10.1371/journal.pone.0220240.

[Iodine-induced thyroid dysfunction].

Eilsberger F, Luster M, Feldkamp J

Medizinische Klinik, Intensivmedizin und Notfallmedizin 2021; (116(4)):307-311 doi:10.1007/s00063-020-00699-8.

No Longterm Severe Thyroid Dysfunction Seen In Patients With Preexisting Reduced Serum Tt3 Concentrations After A Single Large Dose Of Iodinated Contrast.

Hai-Long S, Qin Q, Yuan-Yuan L, Bing-Rang Z

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2020; (26(8)):840-845 doi:10.4158/EP-2019-0600.

Iodine supplementation for pregnant women: a cross-sectional national interventional study.

Delshad H, Raeisi A, Abdollahi Z, et al.

Journal of endocrinological investigation 2021; (44(10)):2307-2314 doi:10.1007/s40618-021-01538-z.

The effects of amiodarone on thyroid function in pediatric and adolescent patients.

Barrett B, Bauer AJ

Current opinion in pediatrics 2021; (33(4)):436-441 doi:10.1097/MOP.0000000000001040.

Differences between immunotherapy-induced and primary hypophysitis-a multicenter retrospective study.

Amereller F, Deutschbein T, Joshi M, et al.

Pituitary 2022; (25(1)):152-158 doi:10.1007/s11102-021-01182-z.

Seasonal effects on urinary iodine concentrations in women of reproductive age: An observational study in Tanzania and South Africa.

Arns-Glaser L, Zandberg L, Assey VD, et al.

The American journal of clinical nutrition 2022; (115(1)):298-309 doi:10.1093/ajcn/nqab327.

Iodine nutrition status and thyroid autoimmunity during pregnancy: a cross-sectional study of 4635 pregnant women.

Chen X, Wu C, Wang Z, et al.

Nutrition journal 2022; (21(1)):7 doi:10.1186/s12937-022-00760-6.

Myxedema Coma Precipitated by Iohexol: Case Report and Brief Literature Review on the Wolff-Chaikoff Effect.

Tng EL, Aung AT, Chong N

Thyroid : official journal of the American Thyroid Association 2022; (32(6)):739-743 doi:10.1089/thy.2022.0021.

Adverse Effects on the Thyroid of Chinese Pregnant Women Exposed to Long-Term Iodine Excess: Optimal and Safe Tolerable Upper Intake Levels of Iodine.

Wu W, Guo W, Zhang N, et al.

Nutrients 2023; (15(7)) doi:10.3390/nu15071635.

Iodine-Induced Hypothyroidism After Chemoembolization With Ethiodized Oil: A Case of Failure to Escape From Wolff-Chaikoff Effect (WCE).

Campos AC, Cruz Carvalho I, Sarmento S, Fonseca T

Cureus 2023; (15(5)):e39352 doi:10.7759/cureus.39352.

Thyroid dysfunction associated with iodine-contrast media: A real-world pharmacovigilance study based on the FDA adverse event reporting system.

Huang L, Luo Y, Chen ZL, et al.

Heliyon 2023; (9(11)):e21694 doi:10.1016/j.heliyon.2023.e21694.

Selenium bioavailability modulates the sensitivity of thyroid cells to iodide excess.

Oglio R, Rodriguez C, Salvarredi L, et al.

Chemico-biological interactions 2024; (387()):110810 doi:10.1016/j.cbi.2023.110810.

One children's hospital planning and development process to adhere to the FDA recommendation that babies and young children undergo thyroid function testing after receiving an injection of iodine-containing contrast media for medical imaging.

Bardo DME, Samis JH, Josefson JL, et al.

Pediatric radiology 2024; (54(1)):27-33 doi:10.1007/s00247-023-05806-3.

Monitoring thyroid function during amiodarone use.

Sharma P, Sheikh R, Siribaddana N, et al.

British journal of hospital medicine (London, England : 2005) 2024; (85(1)):1-5 doi:10.12968/hmed.2023.0214.

Thyroid Dysfunction Risk After Iodinated Contrast Media Administration: A Prospective Longitudinal Cohort Analysis.

Sohn SY, Inoue K, Bashir MT, et al.

The Journal of clinical endocrinology and metabolism 2025; (110(4)):e1204-e1210 doi:10.1210/clinem/dgae304.

Risks of Iodine Excess.

Sohn SY, Inoue K, Rhee CM, Leung AM

Endocrine reviews 2024; (45(6)):858-879 doi:10.1210/endrev/bnae019.

Iodinated Contrast-Induced Hypothyroidism in An Infant after Enteral Contrast Enema: A Case-Report and Systematic Review

Pijpers AGH, Zoetelief SE, Eeftinck Schattenkerk LD, et al.

Journal of clinical research in pediatric endocrinology 2025; (17(4)):494-501 doi:10.4274/jcrpe.galenos.2024.2023-12-2.

Effects of iodine contrast media on thyroid function - a prospective study.

Carlqvist J, Nyman U, Brandberg J, et al.

European thyroid journal 2024; (13(6)).

Effect of Maternal Iodine Excess during Pregnancy on Neonatal Thyroid Function and Neurodevelopmental Status at 12 Weeks.

Rao DK, Jindal A, Dabas A, et al.

Journal of the ASEAN Federation of Endocrine Societies 2024; (39(2)):27-32 doi:10.15605/jafes.039.02.12.

Incidence and Risk Factors for Amiodarone-Induced Thyroid Dysfunction: A Nationwide Retrospective Cohort Study.

Sohn SY, Kim YJ, Cho S, Cho SW

American journal of cardiovascular drugs : drugs, devices, and other interventions 2025; (25(3)):419-425 doi:10.1007/s40256-024-00717-6.

The effect of cardiac catheterization on thyroid functions in infants with congenital heart diseases: a prospective observational study.

Elbaz BA, Elmarsafawy HM, Laimon WN

European journal of pediatrics 2025; (184(2)):137 doi:10.1007/s00431-024-05934-4.

Delayed Diagnosis of Myxedema Coma in a Patient With Concurrent Severe Intracranial Atherosclerotic Disease.

Tolaymat A, Mitchell G

Cureus 2025; (17(5)):e83339 doi:10.7759/cureus.83339.

Hypothyroidism and Hyperthyroidism in an Adolescent With Complex Congenital Heart Disease Exposed to Iodinated Contrast Media: Case Report.

Sandberg ES, Fisher JS

Case reports in endocrinology 2025; (2025()):6859739 doi:10.1155/crie/6859739.

Urine iodine concentration in hospitalised infants with thyroid dysfunction.

Hou C, Jack M, Hobbs A, et al.

Thyroid research 2025; (18(1)):40 doi:10.1186/s13044-025-00256-5.

Unexpected Onset of Severe Hypothyroidism Following a Thyroid Technetium Scan in a Young Patient With Graves' Disease: A Case Report.

Jamal HF, Ebrahim SM, Alsaie AA, et al.

Cureus 2025; (17(7)):e87460 doi:10.7759/cureus.87460.

Clinical course of myxedema coma in an Alzheimer's disease patient and co-founding of J wave: A case report.

Shalak M, Sreemantula HS, Amaechi E, Mousavi S

Journal of family medicine and primary care 2025; (14(10)):4400-4403 doi:10.4103/jfmpc.jfmpc_1877_24.

Myxedema Coma as the Initial Presentation of Undiagnosed Hypothyroidism: A Rare but Reversible Emergency.

Mansoor R, Iqbal M, Kakkar T, et al.

Cureus 2025; (17(12)):e98621 doi:10.7759/cureus.98621.

Iodine and Thyroid Dysfunction in Ageing: Nutritional, Pharmacologic, and Microbial Modifiers in Older Adults.

Zugravu CA, Petre M, Constantin C

Geriatrics (Basel, Switzerland) 2026; (11(1)) doi:10.3390/geriatrics11010012.

Risk of post-contrast thyroid dysfunction in non-toxic goiter: a matched cohort study.

Lee W, Kor CT, Liu YT

European journal of endocrinology 2026; (194(4)):555-565 doi:10.1093/ejendo/lvag069.

American Thyroid Association 2026 Guidelines for Thyroid Disease in Preconception, Pregnancy, and Postpartum.

Korevaar TIM, Leung AM, Alexander EK, et al.

Thyroid : official journal of the American Thyroid Association 2026; (36(5)):481-544 doi:10.1177/10507256261445624.

The effect of iodinated contrast media on thyroid (dys)function in children.

Vancauwenbergh F, Decallonne B, Rochtus AM

European thyroid journal 2026; (15(4)) doi:10.1530/ETJ-26-0036.