Research & Literature

The lingering effects of a busted myth--false time limits in stroke rehabilitation.

Sun Y, Boots J, Zehr EP

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2015; (40(8)):858-61 doi:10.1139/apnm-2014-0523.

Dual antiplatelet therapy with clopidogrel and aspirin after ischemic stroke: A review of the evidence.

Davis KA, Miyares MA, Dietrich E

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 2015; (72(19)):1623-9 doi:10.2146/ajhp140804.

Time to Reperfusion and Treatment Effect for Acute Ischemic Stroke: A Randomized Clinical Trial.

Fransen PS, Berkhemer OA, Lingsma HF, et al.

JAMA neurology 2016; (73(2)):190-6 doi:10.1001/jamaneurol.2015.3886.

Relationship Between Collateral Status, Contrast Transit, and Contrast Density in Acute Ischemic Stroke.

Kawano H, Bivard A, Lin L, et al.

Stroke 2016; (47(3)):742-9 doi:10.1161/STROKEAHA.115.011320.

When a Single Antiplatelet Agent for Stroke Prevention Is Not Enough: Current Evidence and Future Applications of Dual Antiplatelet Therapy.

Yuan K, Kim AS

Current treatment options in cardiovascular medicine 2016; (18(4)):26 doi:10.1007/s11936-016-0449-7.

One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke.

Amarenco P, Lavallée PC, Labreuche J, et al.

The New England journal of medicine 2016; (374(16)):1533-42 doi:10.1056/NEJMoa1412981.

The prevalence of fatigue after stroke: A systematic review and meta-analysis.

Cumming TB, Packer M, Kramer SF, English C

International journal of stroke : official journal of the International Stroke Society 2016; (11(9)):968-977 doi:10.1177/1747493016669861.

Transient Ischemic Attacks: Advances in Diagnosis and Management in the Emergency Department.

Duca A, Jagoda A

Emergency medicine clinics of North America 2016; (34(4)):811-835 doi:10.1016/j.emc.2016.06.007.

Clinical Mimics: An Emergency Medicine-Focused Review of Stroke Mimics.

Long B, Koyfman A

The Journal of emergency medicine 2017; (52(2)):176-183 doi:10.1016/j.jemermed.2016.09.021.

Therapies for Hemorrhagic Transformation in Acute Ischemic Stroke.

Stone JA, Willey JZ, Keyrouz S, et al.

Current treatment options in neurology 2017; (19(1)):1 doi:10.1007/s11940-017-0438-5.

Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke: Primary Results of the STRATIS Registry.

Mueller-Kronast NH, Zaidat OO, Froehler MT, et al.

Stroke 2017; (48(10)):2760-2768 doi:10.1161/STROKEAHA.117.016456.

The Nottingham Fatigue After Stroke (NotFAST) study: results from follow-up six months after stroke.

Hawkins L, Lincoln NB, Sprigg N, et al.

Topics in stroke rehabilitation 2017; (24(8)):592-596 doi:10.1080/10749357.2017.1368912.

Patent Foramen Ovale Closure or Anticoagulation vs. Antiplatelets after Stroke.

Mas JL, Derumeaux G, Guillon B, et al.

The New England journal of medicine 2017; (377(11)):1011-1021 doi:10.1056/NEJMoa1705915.

Time to Endovascular Treatment and Outcome in Acute Ischemic Stroke: MR CLEAN Registry Results.

Mulder MJHL, Jansen IGH, Goldhoorn RB, et al.

Circulation 2018; (138(3)):232-240 doi:10.1161/CIRCULATIONAHA.117.032600.

Rivaroxaban for Stroke Prevention after Embolic Stroke of Undetermined Source.

Hart RG, Sharma M, Mundl H, et al.

The New England journal of medicine 2018; (378(23)):2191-2201 doi:10.1056/NEJMoa1802686.

Dextromethorphan/Quinidine for Pseudobulbar Affect Following Stroke: Safety and Effectiveness in the PRISM II Trial.

Zorowitz RD, Alexander DN, Formella AE, et al.

PM & R : the journal of injury, function, and rehabilitation 2018; doi:10.1016/j.pmrj.2018.06.003.

Acute Blood Pressure Management in Acute Ischemic Stroke and Spontaneous Cerebral Hemorrhage.

McDermott M, Sozener CB

Current treatment options in neurology 2018; (20(9)):39 doi:10.1007/s11940-018-0523-4.

Pseudobulbar affect after stroke: a narrative review.

Girotra T, Lowe F, Feng W

Topics in stroke rehabilitation 2018; 1-7 doi:10.1080/10749357.2018.1499300.

Advanced Neuroimaging of Acute Ischemic Stroke: Penumbra and Collateral Assessment.

Heit JJ, Zaharchuk G, Wintermark M

Neuroimaging clinics of North America 2018; (28(4)):585-597 doi:10.1016/j.nic.2018.06.004.

Non-Vitamin K Antagonist Oral Anticoagulants in the Treatment of Atrial Fibrillation.

Fanaroff AC, Ohman EM

Annual review of medicine 2019; (70()):61-75 doi:10.1146/annurev-med-042617-092334.

Management of Stroke in the Neurocritical Care Unit.

Venkatasubba Rao CP, Suarez JI

Continuum (Minneapolis, Minn.) 2018; (24(6)):1658-1682 doi:10.1212/CON.0000000000000670.

European Stroke Organisation (ESO) - European Society for Minimally Invasive Neurological Therapy (ESMINT) Guidelines on Mechanical Thrombectomy in Acute Ischemic Stroke.

Turc G, Bhogal P, Fischer U, et al.

Journal of neurointerventional surgery 2023; (15(8)):e8 doi:10.1136/neurintsurg-2018-014569.

Comparison of statins for secondary prevention in patients with ischemic stroke or transient ischemic attack: a systematic review and network meta-analysis.

Tramacere I, Boncoraglio GB, Banzi R, et al.

BMC medicine 2019; (17(1)):67 doi:10.1186/s12916-019-1298-5.

Left Atrial Volume Index Is Associated With Cardioembolic Stroke and Atrial Fibrillation Detection After Embolic Stroke of Undetermined Source.

Jordan K, Yaghi S, Poppas A, et al.

Stroke 2019; (50(8)):1997-2001 doi:10.1161/STROKEAHA.119.025384.

Canadian Stroke Best Practice Recommendations: Mood, Cognition and Fatigue following Stroke, 6th edition update 2019.

Lanctôt KL, Lindsay MP, Smith EE, et al.

International journal of stroke : official journal of the International Stroke Society 2020; (15(6)):668-688 doi:10.1177/1747493019847334.

Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association.

Powers WJ, Rabinstein AA, Ackerson T, et al.

Stroke 2019; (50(12)):e344-e418 doi:10.1161/STR.0000000000000211.

A Comparison of Two LDL Cholesterol Targets after Ischemic Stroke.

Amarenco P, Kim JS, Labreuche J, et al.

The New England journal of medicine 2020; (382(1)):9 doi:10.1056/NEJMoa1910355.

Cryptogenic Stroke: Diagnostic Workup and Management.

Mac Grory B, Flood SP, Apostolidou E, Yaghi S

Current treatment options in cardiovascular medicine 2019; (21(11)):77 doi:10.1007/s11936-019-0786-4.

Antithrombotic treatment for secondary prevention of stroke and other thromboembolic events in patients with stroke or transient ischemic attack and non-valvular atrial fibrillation: A European Stroke Organisation guideline.

Klijn CJ, Paciaroni M, Berge E, et al.

European stroke journal 2019; (4(3)):198-223 doi:10.1177/2396987319841187.

From "Time is Brain" to "Imaging is Brain": A Paradigm Shift in the Management of Acute Ischemic Stroke.

Puig J, Shankar J, Liebeskind D, et al.

Journal of neuroimaging : official journal of the American Society of Neuroimaging 2020; (30(5)):562-571 doi:10.1111/jon.12693.

Endovascular Treatment of Acute Ischemic Stroke.

Silva GS, Nogueira RG

Continuum (Minneapolis, Minn.) 2020; (26(2)):310-331 doi:10.1212/CON.0000000000000852.

Stroke Prevention With the PCSK9 (Proprotein Convertase Subtilisin-Kexin Type 9) Inhibitor Evolocumab Added to Statin in High-Risk Patients With Stable Atherosclerosis.

Giugliano RP, Pedersen TR, Saver JL, et al.

Stroke 2020; (51(5)):1546-1554 doi:10.1161/STROKEAHA.119.027759.

Acute Ischemic Stroke: Acute Management and Selection for Endovascular Therapy.

Dhand S, O'Connor P, Hughes C, Lin SP

Seminars in interventional radiology 2020; (37(2)):109-118 doi:10.1055/s-0040-1709152.

Post-stroke fatigue: how it relates to motor fatigability and other modifiable factors in people with chronic stroke.

Rahamatali M, De Bont N, Valet M, et al.

Acta neurologica Belgica 2021; (121(1)):181-189 doi:10.1007/s13760-020-01453-9.

Non-vitamin K oral anticoagulants for secondary stroke prevention in patients with atrial fibrillation.

Diener HC, Hankey GJ, Easton JD, et al.

European heart journal supplements : journal of the European Society of Cardiology 2020; (22(Suppl I)):I13-I21 doi:10.1093/eurheartj/suaa104.

Diagnosis and Management of Transient Ischemic Attack and Acute Ischemic Stroke: A Review.

Mendelson SJ, Prabhakaran S

JAMA 2021; (325(11)):1088-1098 doi:10.1001/jama.2020.26867.

European Stroke Organisation (ESO) guidelines on intravenous thrombolysis for acute ischaemic stroke.

Berge E, Whiteley W, Audebert H, et al.

European stroke journal 2021; (6(1)):I-LXII doi:10.1177/2396987321989865.

A sudden and severe depressive episode after a left cingulate gyrus stroke: a case report of post-stroke depression and review of literature.

Ribeiro NF, Madruga L

Journal of neural transmission (Vienna, Austria : 1996) 2021; (128(5)):711-716 doi:10.1007/s00702-021-02334-y.

[Pseudobulbar affect in stroke patients in Argentina].

Alet M, Segamarchi C, Claverie S, et al.

Vertex (Buenos Aires, Argentina) 2020; (XXX(148)):1-5 doi:10.53680/vertex.v30i148.123.

Antihypertensive Drugs for Secondary Prevention After Ischemic Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis.

Boncoraglio GB, Del Giovane C, Tramacere I

Stroke 2021; (52(6)):1974-1982 doi:10.1161/STROKEAHA.120.031945.

Benefits and Risks of Dual Versus Single Antiplatelet Therapy for Secondary Stroke Prevention: A Systematic Review for the 2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack.

Brown DL, Levine DA, Albright K, et al.

Stroke 2021; (52(7)):e468-e479 doi:10.1161/STR.0000000000000377.

Hemorrhagic Transformation in Ischemic Stroke and the Role of Inflammation.

Spronk E, Sykes G, Falcione S, et al.

Frontiers in neurology 2021; (12()):661955 doi:10.3389/fneur.2021.661955.

Four Decades of Ischemic Penumbra and Its Implication for Ischemic Stroke.

Yang SH, Liu R

Translational stroke research 2021; (12(6)):937-945 doi:10.1007/s12975-021-00916-2.

European Stroke Organisation expedited recommendation for the use of short-term dual antiplatelet therapy early after minor stroke and high-risk TIA.

Dawson J, Merwick Á, Webb A, et al.

European stroke journal 2021; (6(2)):CLXXXVII-CXCI doi:10.1177/23969873211000877.

New Insights Into the Roles of Microglial Regulation in Brain Plasticity-Dependent Stroke Recovery.

Yu F, Huang T, Ran Y, et al.

Frontiers in cellular neuroscience 2021; (15()):727899 doi:10.3389/fncel.2021.727899.

Rationale for a Clinical Trial That Compares Acute Stroke Rehabilitation at Inpatient Rehabilitation Facilities to Skilled Nursing Facilities: Challenges and Opportunities.

Simmonds KP, Burke J, Kozlowski AJ, et al.

Archives of physical medicine and rehabilitation 2022; (103(6)):1213-1221 doi:10.1016/j.apmr.2021.08.004.

Ischemic stroke mimics: A comprehensive review.

Pohl M, Hesszenberger D, Kapus K, et al.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2021; (93()):174-182 doi:10.1016/j.jocn.2021.09.025.

Penumbra in Acute Ischemic Stroke.

Yi Y, Liu Z, Wang M, et al.

Current neurovascular research 2021; (18(5)):572-585 doi:10.2174/1567202619666211231094046.

Direct Oral Anticoagulants Versus Warfarin in Patients With Atrial Fibrillation: Patient-Level Network Meta-Analyses of Randomized Clinical Trials With Interaction Testing by Age and Sex.

Carnicelli AP, Hong H, Connolly SJ, et al.

Circulation 2022; (145(4)):242-255 doi:10.1161/CIRCULATIONAHA.121.056355.

The Role of Lipid-Lowering Treatment in the Secondary Prevention of Ischemic Stroke.

Tsankof A, Tziomalos K

Diseases (Basel, Switzerland) 2021; (10(1)) doi:10.3390/diseases10010003.

Evaluation and Prediction of Post-stroke Cerebral Edema Based on Neuroimaging.

Zhang X, Huang P, Zhang R

Frontiers in neurology 2021; (12()):763018 doi:10.3389/fneur.2021.763018.

Non-vitamin K antagonist oral anticoagulants in patients with valvular heart disease.

Fanaroff AC, Vora AN, Lopes RD

European heart journal supplements : journal of the European Society of Cardiology 2022; (24(Suppl A)):A19-A31 doi:10.1093/eurheartj/suab151.

Clinical Differences Between Stroke and Stroke Mimics in Code Stroke Patients.

Kim T, Jeong HY, Suh GJ

Journal of Korean medical science 2022; (37(7)):e54 doi:10.3346/jkms.2022.37.e54.

Hemorrhagic Transformation in Acute Ischemic Stroke: A Quantitative Systematic Review.

Honig A, Percy J, Sepehry AA, et al.

Journal of clinical medicine 2022; (11(5)) doi:10.3390/jcm11051162.

Is the TOAST Classification Suitable for Use in Personalized Medicine in Ischemic Stroke?

Simonsen SA, West AS, Heiberg AV, et al.

Journal of personalized medicine 2022; (12(3)) doi:10.3390/jpm12030496.

Clinical Imaging of the Penumbra in Ischemic Stroke: From the Concept to the Era of Mechanical Thrombectomy.

Chalet L, Boutelier T, Christen T, et al.

Frontiers in cardiovascular medicine 2022; (9()):861913 doi:10.3389/fcvm.2022.861913.

Impact of Neuroimaging Patterns for the Detection of Atrial Fibrillation by Implantable Loop Recorders in Patients With Embolic Stroke of Undetermined Source.

Kim JG, Boo K, Kang CH, et al.

Frontiers in neurology 2022; (13()):905998 doi:10.3389/fneur.2022.905998.

Regional computed tomography perfusion deficits in patients with hypoglycemia: two case reports.

Sartor-Pfeiffer J, Lingel M, Stefanou MI, et al.

Neurological research and practice 2022; (4(1)):36 doi:10.1186/s42466-022-00201-z.

Cerebral edema after ischemic stroke: Pathophysiology and underlying mechanisms.

Gu Y, Zhou C, Piao Z, et al.

Frontiers in neuroscience 2022; (16()):988283 doi:10.3389/fnins.2022.988283.

Early Versus Delayed Non-Vitamin K Antagonist Oral Anticoagulant Therapy After Acute Ischemic Stroke in Atrial Fibrillation (TIMING): A Registry-Based Randomized Controlled Noninferiority Study.

Oldgren J, Åsberg S, Hijazi Z, et al.

Circulation 2022; (146(14)):1056-1066 doi:10.1161/CIRCULATIONAHA.122.060666.

European Stroke Organisation (ESO) guideline on pharmacological interventions for long-term secondary prevention after ischaemic stroke or transient ischaemic attack.

Dawson J, Béjot Y, Christensen LM, et al.

European stroke journal 2022; (7(3)):I-II doi:10.1177/23969873221100032.

Navigating Antiplatelet Treatment Options for Stroke: Evidence-Based and Pragmatic Strategies.

Moustafa B, Testai FD

Current neurology and neuroscience reports 2022; (22(11)):789-802 doi:10.1007/s11910-022-01237-z.

A systematic review of the research progress of non-coding RNA in neuroinflammation and immune regulation in cerebral infarction/ischemia-reperfusion injury.

Yang K, Zeng L, Ge A, et al.

Frontiers in immunology 2022; (13()):930171 doi:10.3389/fimmu.2022.930171.

Computed tomographic perfusion abnormalities in acute migraine with aura: Characteristics and comparison with transient ischemic attack.

Strambo D, Nannoni S, Rebordão L, et al.

European stroke journal 2022; (7(4)):431-438 doi:10.1177/23969873221114256.

Diagnosis, Workup, Risk Reduction of Transient Ischemic Attack in the Emergency Department Setting: A Scientific Statement From the American Heart Association.

Amin HP, Madsen TE, Bravata DM, et al.

Stroke 2023; (54(3)):e109-e121 doi:10.1161/STR.0000000000000418.

European Stroke Organisation (ESO) expedited recommendation on tenecteplase for acute ischaemic stroke.

Alamowitch S, Turc G, Palaiodimou L, et al.

European stroke journal 2023; (8(1)):8-54 doi:10.1177/23969873221150022.

Contemporary Antiplatelet and Anticoagulant Therapies for Secondary Stroke Prevention: A Narrative Review of Current Literature and Guidelines.

Bhatia K, Ladd LM, Carr KH, et al.

Current neurology and neuroscience reports 2023; (23(5)):235-262 doi:10.1007/s11910-023-01266-2.

Antiplatelets and antithrombotics in neurointerventional procedures: Guideline update.

Schirmer CM, Bulsara KR, Al-Mufti F, et al.

Journal of neurointerventional surgery 2023; (15(11)):1155-1162 doi:10.1136/jnis-2022-019844.

Proportional Recovery After Stroke: Addressing Concerns Regarding Mathematical Coupling and Ceiling Effects.

Chong B, Wang A, Stinear CM

Neurorehabilitation and neural repair 2023; (37(7)):488-498 doi:10.1177/15459683231177598.

Telaprevir Improves Memory and Cognition in Mice Suffering Ischemic Stroke via Targeting MALT1-Mediated Calcium Overload and Necroptosis.

Zhang YY, Peng JJ, Chen D, et al.

ACS chemical neuroscience 2023; (14(17)):3113-3124 doi:10.1021/acschemneuro.3c00250.

Intensive vs Conventional Blood Pressure Lowering After Endovascular Thrombectomy in Acute Ischemic Stroke: The OPTIMAL-BP Randomized Clinical Trial.

Nam HS, Kim YD, Heo J, et al.

JAMA 2023; (330(9)):832-842 doi:10.1001/jama.2023.14590.

TOAST stroke subtype classification in clinical practice: implications for the Get With The Guidelines-Stroke nationwide registry.

Rathburn CM, Mun KT, Sharma LK, Saver JL

Frontiers in neurology 2024; (15()):1375547 doi:10.3389/fneur.2024.1375547.

Global, regional, and national epidemiology of ischemic stroke from 1990 to 2021.

Hou S, Zhang Y, Xia Y, et al.

European journal of neurology 2024; (31(12)):e16481 doi:10.1111/ene.16481.

Prevalence and associated factors of post-stroke depression in Africa: a systematic review and meta-analysis.

Getachew B, Mulu A

BMC neurology 2024; (24(1)):360 doi:10.1186/s12883-024-03867-x.

Enhancing Stroke Recognition: A Comparative Analysis of Balance and Eyes-Face, Arms, Speech, Time (BE-FAST) and Face, Arms, Speech, Time (FAST) in Identifying Posterior Circulation Strokes.

Tanglay O, Cappelen-Smith C, Parsons MW, Cordato DJ

Journal of clinical medicine 2024; (13(19)) doi:10.3390/jcm13195912.

Contemporary Management of Acute Ischemic Stroke.

Ho JP, Powers WJ

Annual review of medicine 2025; (76(1)):417-429 doi:10.1146/annurev-med-050823-094312.

Associations Between Prenotification and Time to Management in Acute Stroke Patients Transported by Emergency Medical Services.

Jeong YJ, Kim KH, Park JH, et al.

The Journal of emergency medicine 2025; (74()):77-85 doi:10.1016/j.jemermed.2025.02.005.

A pilot comparison of the retention rates of FAST and BEFAST stroke warning-sign mnemonics.

Guo S, Saver JL

Frontiers in neurology 2025; (16()):1624800 doi:10.3389/fneur.2025.1624800.

Risk of Ischemic Stroke After Transient Ischemic Attack in Patients Receiving Comprehensive Versus Noncomprehensive Diagnostic Workup: A Systematic Review and Meta-Analysis.

Hejazian SS, Shahjouei S, Sadr AV, et al.

Journal of the American Heart Association 2025; (14(21)):e042175 doi:10.1161/JAHA.125.042175.

Navigating Postacute Care Options for Patients After Hospital Discharge: A Review.

Deardorff WJ, Burke RE, Makam AN

JAMA internal medicine 2026; (186(3)):362-373 doi:10.1001/jamainternmed.2025.7422.

Predictors of post-stroke depression and anxiety at three months following acute ischemic stroke.

Dec-Ćwiek M, Słowik J, Pulyk R, et al.

BMC psychiatry 2026; (26(1)).

Stroke or Seizure? Diagnostic Role of Neuroimaging in Acute Neurologic Mimics.

Tosto F, Lobianco C, Magro G, Pascarella A

NeuroSci 2026; (7(3)) doi:10.3390/neurosci7030071.