Research & Literature

Splenectomy is associated with a higher risk for venous thromboembolism: A prospective cohort study.

Lee DH, Barmparas G, Fierro N, et al.

International journal of surgery (London, England) 2015; (24(Pt A)):27-32.

Is ITP a thrombophilic disorder?

Rodeghiero F

American journal of hematology 2016; (91(1)):39-45 doi:10.1002/ajh.24234.

Eltrombopag Induced Thrombosis: A Case with Acute Myocardial Infarction.

Gunes H, Kivrak T

Current drug safety 2016; (11(2)):174-6 doi:10.2174/1574886311207040255.

Bleeding complications in immune thrombocytopenia.

Arnold DM

Hematology. American Society of Hematology. Education Program 2015; (2015()):237-42 doi:10.1182/asheducation-2015.1.237.

Multicenter Cohort Study Comparing U.S. Management of Inpatient Pediatric Immune Thrombocytopenia to Current Treatment Guidelines.

Witmer CM, Lambert MP, O'Brien SH, Neunert C

Pediatric blood & cancer 2016; (63(7)):1227-31 doi:10.1002/pbc.25961.

Re-evaluation of Need for Bone Marrow Examination in Patients with Isolated Thrombocytopenia Contributors.

Purohit A, Aggarwal M, Singh PK, et al.

Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion 2016; (32(2)):193-6 doi:10.1007/s12288-015-0533-2.

A four-point clinical criteria distinguishes immune thrombocytopenia from acute lymphoblastic leukaemia.

Lum SH, How SJ, Ariffin H, Krishnan S

The Medical journal of Malaysia 2016; (71(1)):28-9.

Medical complications following splenectomy.

Buzelé R, Barbier L, Sauvanet A, Fantin B

Journal of visceral surgery 2016; (153(4)):277-86.

MYH9-related disorder, a probable May-Hegglin anomaly case series: A tertiary care experience.

Kamath V, Gnanasekaran KK, Mammen J

Hematology/oncology and stem cell therapy 2016; (9(4)):137-140 doi:10.1016/j.hemonc.2016.08.002.

Immune Thrombocytopenic Purpura in Children of Eastern Henan Province, China.

Fan QX, Wang CM, Chen SX, et al.

Indian pediatrics 2016; (53(11)):1024-1025.

A Case of Immune Thrombocytopenic Purpura Secondary to Pulmonary Tuberculosis.

Panda S, Meher LK, Dalai SP, et al.

Journal of clinical and diagnostic research : JCDR 2016; (10(10)):OD12-OD13 doi:10.7860/JCDR/2016/21365.8726.

Second-line therapies in immune thrombocytopenia.

Grace RF, Neunert C

Hematology. American Society of Hematology. Education Program 2016; (2016(1)):698-706 doi:10.1182/asheducation-2016.1.698.

Thrombocytopenia and infections.

Franchini M, Veneri D, Lippi G

Expert review of hematology 2017; (10(1)):99-106 doi:10.1080/17474086.2017.1271319.

Patterns and influences in health-related quality of life in children with immune thrombocytopenia: A study from the Dallas ITP Cohort.

Flores A, Klaassen RJ, Buchanan GR, Neunert CE

Pediatric blood & cancer 2017; (64(8)) doi:10.1002/pbc.26405.

State of the art - how I manage immune thrombocytopenia.

Cooper N

British journal of haematology 2017; (177(1)):39-54 doi:10.1111/bjh.14515.

Inflammatory Bowel Disease and Immune Thrombocytopenic Purpura: Combined Immune Dysregulation in an Adolescent.

Queliza K, Ihekweazu FD, Ali A, Kellermayer R

Annals of clinical and laboratory science 2017; (47(2)):226-228.

Proactive use of eltrombopag before the onset of clinical bleeding in two children with immune thrombocytopenia and lifestyle restrictions.

Bergmann S

Clinical case reports 2017; (5(10)):1660-1663 doi:10.1002/ccr3.1086.

Mean platelet volume at baseline and immune thrombocytopenia relapse in Chinese newly-diagnosed patients: a retrospective cohort study.

Chen C, Song J, Wang Q, et al.

Hematology (Amsterdam, Netherlands) 2018; (23(9)):646-652 doi:10.1080/10245332.2018.1461317.

Intravenous immunoglobulin vs observation in childhood immune thrombocytopenia: a randomized controlled trial.

Heitink-Pollé KMJ, Uiterwaal CSPM, Porcelijn L, et al.

Blood 2018; (132(9)):883-891 doi:10.1182/blood-2018-02-830844.

Successful Treatment of Idiopathic Thrombocytopenic Purpura After Liver Transplant: A Case Report.

Hoveidaei AH, Soufi H, Dehghani SM, Imanieh MH

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 2020; (18(5)):649-652 doi:10.6002/ect.2018.0083.

Bone Marrow Disease Profile in Geriatric Patients: An Institutional Experience.

Gulati A, Mandal T, Kaushal V, et al.

Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion 2018; (34(3)):540-543 doi:10.1007/s12288-017-0871-3.

Evidence-based management of immune thrombocytopenia: ASH guideline update.

Neunert CE, Cooper N

Hematology. American Society of Hematology. Education Program 2018; (2018(1)):568-575 doi:10.1182/asheducation-2018.1.568.

The sensitivity and specificity of platelet autoantibody testing in immune thrombocytopenia: a systematic review and meta-analysis of a diagnostic test.

Vrbensky JR, Moore JE, Arnold DM, et al.

Journal of thrombosis and haemostasis : JTH 2019; (17(5)):787-794 doi:10.1111/jth.14419.

Fostamatinib for the treatment of chronic immune thrombocytopenia.

Connell NT, Berliner N

Blood 2019; (133(19)):2027-2030 doi:10.1182/blood-2018-11-852491.

Epidemiology and Clinical Manifestations of Immune Thrombocytopenia.

Kohli R, Chaturvedi S

Hamostaseologie 2019; (39(3)):238-249 doi:10.1055/s-0039-1683416.

Treatment of primary and secondary immune thrombocytopenia.

Kado R, McCune WJ

Current opinion in rheumatology 2019; (31(3)):213-222 doi:10.1097/BOR.0000000000000599.

Cardiovascular and bleeding outcomes in a population-based cohort of patients with chronic immune thrombocytopenia.

Adelborg K, Kristensen NR, Nørgaard M, et al.

Journal of thrombosis and haemostasis : JTH 2019; (17(6)):912-924 doi:10.1111/jth.14446.

Disseminated tuberculosis with severe immune thrombocytopenia.

Rama Krishna M, Gottam US, Mahendra N

Respiratory medicine case reports 2019; (27()):100812 doi:10.1016/j.rmcr.2019.02.013.

Fostamatinib for the treatment of immune thrombocytopenia in adults.

Moore DC, Gebru T, Muslimani A

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 2019; (76(11)):789-794 doi:10.1093/ajhp/zxz052.

Proposal of treatment algorithm for immune thromocytopenia in adult patients of a hematology service at a referral center in Northeastern Brazil.

Ribeiro RA, Galiza Neto GC, Furtado ADS, et al.

Hematology, transfusion and cell therapy 2019; (41(3)):253-261 doi:10.1016/j.htct.2018.10.005.

Immune thrombocytopenia associated with Helicobacter pylori - unclear associative mechanisms.

Marques AR, Sousa L, Mendes M, Apolinário I

Hematology, transfusion and cell therapy 2019; (41(3)):272-274 doi:10.1016/j.htct.2018.12.002.

[Protocol for the study and treatment of primary immune thrombocytopenia: PTI-2018].

Monteagudo E, Astigarraga I, Cervera Á, et al.

Anales de pediatria 2019; (91(2)):127.e1-127.e10 doi:10.1016/j.anpedi.2019.04.014.

The child with immune thrombocytopenia: to treat or not to treat, is that still the question?

Cooper N, Cines DB

Haematologica 2019; (104(11)):2132-2134 doi:10.3324/haematol.2019.229179.

Sequence of Splenectomy and Rituximab for the Treatment of Steroid-Refractory Immune Thrombocytopenia: Does It Matter?

Hammond WA, Vishnu P, Rodriguez EM, et al.

Mayo Clinic proceedings 2019; (94(11)):2199-2208 doi:10.1016/j.mayocp.2019.05.024.

Primary Immune Thrombocytopenia: A Translational Research Model for Autoimmune Diseases.

Andrès E

Journal of clinical medicine 2019; (8(11)) doi:10.3390/jcm8111971.

Updated international consensus report on the investigation and management of primary immune thrombocytopenia.

Provan D, Arnold DM, Bussel JB, et al.

Blood advances 2019; (3(22)):3780-3817 doi:10.1182/bloodadvances.2019000812.

Bone marrow examination in geriatric patients-An institutional experience from the north Himalayan region of India.

Chandra H, Gupta AK, Arathi K, et al.

Journal of family medicine and primary care 2019; (8(12)):3931-3934 doi:10.4103/jfmpc.jfmpc_792_19.

Lifting the fog over ITP.

Choi PY

Platelets 2020; (31(3)):283-284 doi:10.1080/09537104.2020.1732747.

Health-Related Quality of Life and Burden of Fatigue in Chinese Patients with Immune Thrombocytopenia: A Cross-Sectional Study.

Yang R, Yao H, Lin L, et al.

Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion 2020; (36(1)):104-111 doi:10.1007/s12288-019-01124-7.

COVID-19-associated immune thrombocytopenia.

Bomhof G, Mutsaers PGNJ, Leebeek FWG, et al.

British journal of haematology 2020; (190(2)):e61-e64 doi:10.1111/bjh.16850.

Fatigue in children and adolescents with immune thrombocytopenia.

Grace RF, Klaassen RJ, Shimano KA, et al.

British journal of haematology 2020; (191(1)):98-106 doi:10.1111/bjh.16751.

Recurrence of immune thrombocytopenia at the time of SARS-CoV-2 infection.

Merli M, Ageno W, Sessa F, et al.

Annals of hematology 2020; (99(8)):1951-1952 doi:10.1007/s00277-020-04130-2.

Risk stratification and outcomes of intracranial hemorrhage in patients with immune thrombocytopenia under 60 years of age.

Zhao P, Hou M, Liu Y, et al.

Platelets 2021; (32(5)):633-641 doi:10.1080/09537104.2020.1786042.

Clinical characteristics, management and outcome of COVID-19-associated immune thrombocytopenia: a French multicentre series.

Mahévas M, Moulis G, Andres E, et al.

British journal of haematology 2020; (190(4)):e224-e229 doi:10.1111/bjh.17024.

Romiplostim for the Treatment of Immune Thrombocytopenia: Spotlight on Patient Acceptability and Ease of Use.

Gilbert MM, Grimes AB, Kim TO, Despotovic JM

Patient preference and adherence 2020; (14()):1237-1250 doi:10.2147/PPA.S192481.

Perioperative oral eltrombopag versus intravenous immunoglobulin in patients with immune thrombocytopenia: a non-inferiority, multicentre, randomised trial.

Arnold DM, Heddle NM, Cook RJ, et al.

The Lancet. Haematology 2020; (7(9)):e640-e648 doi:10.1016/S2352-3026(20)30227-1.

Immune thrombocytopenic purpura associated with coronavirus disease 2019 infection in an asymptomatic young healthy patient.

Lobos P, Lobos C, Aravena P

JAAD case reports 2020; (6(11)):1129-1131 doi:10.1016/j.jdcr.2020.08.037.

Risk Factors and Psychological Analysis of Chronic Immune Thrombocytopenia in Children.

Sun Y, Long S, Liu W

International journal of general medicine 2020; (13()):1675-1683 doi:10.2147/IJGM.S290459.

A Case of Epistaxis as the First Sign of Acute Idiopathic Thrombocytopenic Purpura.

Tajima S, Matsumoto F, Anzai T, et al.

Case reports in otolaryngology 2021; (2021()):6612939 doi:10.1155/2021/6612939.

Misdiagnosed thrombocytopenia in children and adolescents: analysis of the Pediatric and Adult Registry on Chronic ITP.

Schifferli A, Heiri A, Imbach P, et al.

Blood advances 2021; (5(6)):1617-1626 doi:10.1182/bloodadvances.2020003004.

Epidemiology and Viral Etiology of Pediatric Immune Thrombocytopenia through Korean Public Health Data Analysis.

Lim JH, Kim YK, Min SH, et al.

Journal of clinical medicine 2021; (10(7)) doi:10.3390/jcm10071356.

Surgical Control of Bleeding From Ovarian Torsion in the Setting of Immune Thrombocytopenic Purpura Without Splenectomy.

Shaw TB, Ma B, Barazza M, Sawaya D

The American surgeon 2023; (89(11)):4884-4887 doi:10.1177/00031348211011128.

Immune thrombocytopenia in two infant cases managed with eltrombopag.

Ceglie G, Nocentini G, De Gennaro F, et al.

Pediatric blood & cancer 2021; (68(9)):e29120 doi:10.1002/pbc.29120.

Immune thrombocytopenia in a 68-year-old woman after COVID-19 vaccination.

Kenney A, Adhikari A

Clinical case reports 2021; (9(8)):e04689 doi:10.1002/ccr3.4689.

Abnormalities of bone marrow B cells and plasma cells in primary immune thrombocytopenia.

Yu TS, Wang HY, Zhao YJ, et al.

Blood advances 2021; (5(20)):4087-4101 doi:10.1182/bloodadvances.2020003860.

Piperacillin-Tazobactam-Induced Immune Thrombocytopenia: A Case Report.

Kiliaki S

Journal of pharmacy practice 2023; (36(2)):451-452 doi:10.1177/08971900211048140.

Primary immune thrombocytopenia in very elderly patients: particularities in presentation and management: results from the prospective CARMEN-France Registry.

Sokal A, de Nadaï T, Maquet J, et al.

British journal of haematology 2022; (196(5)):1262-1270 doi:10.1111/bjh.17935.

Updated guidelines for immune thrombocytopenic purpura: Expanded management options.

DeSouza S, Angelini D

Cleveland Clinic journal of medicine 2021; (88(12)):664-668 doi:10.3949/ccjm.88a.20201.

An Unusual Cause of Secondary ITP in a 34-Year-Old Hispanic Male.

Bangolo A, Ahmed M, Atoot A, et al.

Case reports in hematology 2021; (2021()):7965930 doi:10.1155/2021/7965930.

Assessment and Management of Immune Thrombocytopenia (ITP) in the Emergency Department: Current Perspectives.

Zitek T, Weber L, Pinzon D, Warren N

Open access emergency medicine : OAEM 2022; (14()):25-34 doi:10.2147/OAEM.S331675.

Patterns of Bone Marrow Confirmed Malignant and Non-Malignant Hematological Disorders in Patients with Abnormal Hematological Parameters in Northeast Ethiopia.

Ebrahim H, Fisha T, Debash H, Bisetegn H

Journal of blood medicine 2022; (13()):51-60 doi:10.2147/JBM.S346091.

Management of immune thrombocytopenia: 2022 update of Korean experts recommendations.

Park YH, Kim DY, Kim S, et al.

Blood research 2022; (57(1)):20-28 doi:10.5045/br.2022.2022043.

Thrombocytopenia and insufficient thrombopoietin production in human small-for-gestational-age infants.

Takeshita S, Kakita H, Asai S, et al.

Pediatric research 2023; (93(3)):619-624 doi:10.1038/s41390-022-02107-7.

Primary immune thrombocytopenia: a 'diagnosis of exclusion'?

Visweshwar N, Ayala I, Jaglal M, et al.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2022; (33(6)):289-294 doi:10.1097/MBC.0000000000001144.

Quick drop of platelet counts in children with chronic immune thrombocytopenia after COVID-19 mRNA vaccination: case reports.

Lassandro G, Carriero F, Palladino V, et al.

Clinical and experimental vaccine research 2022; (11(3)):290-293 doi:10.7774/cevr.2022.11.3.290.

Validation of immunofluorescence analysis of blood smears in patients with inherited platelet disorders.

Zaninetti C, Leinøe E, Lozano ML, et al.

Journal of thrombosis and haemostasis : JTH 2023; (21(4)):1010-1019 doi:10.1016/j.jtha.2022.12.031.

Successful Kidney Transplantation in MYH-9-Related Disease Presenting with Severe Macrothrombocytopenia

Bülbül MC, Avcı Ş, Yelken B, et al.

Turkish journal of haematology : official journal of Turkish Society of Haematology 2023; (40(3)):232-233 doi:10.4274/tjh.galenos.2023.2023-0138.

Acalabrutinib and steroid for autoimmune thrombocytopenia due to relapsed chronic lymphocytic leukemia with severe bone marrow infiltration.

Oyama T, Yasunaga M, Jona M, et al.

Journal of clinical and experimental hematopathology : JCEH 2023; (63(3)):187-192 doi:10.3960/jslrt.23023.

Reference guide for the diagnosis of adult primary immune thrombocytopenia, 2023 edition.

Kashiwagi H, Kuwana M, Murata M, et al.

International journal of hematology 2024; (119(1)):1-13 doi:10.1007/s12185-023-03672-1.

Identification of an Unmet Medical Need: Height of Depression, Hypersomnia, and Sleep Apnea Positively Correlate With the Level of Fatigue in Patients With Immune Thrombocytopenia.

Alesci RS, Hecking C, Weissmann MV

Cureus 2023; (15(10)):e47003 doi:10.7759/cureus.47003.

Fatigue and health-related quality of life in patients with immune thrombocytopenia: a longitudinal assessment in China.

Zhang W, Xie S, Fu R, et al.

Expert review of hematology 2023; (16(12)):1125-1133 doi:10.1080/17474086.2023.2286730.

Idiopathic Thrombocytopenic Purpura: Current Limitations and Management.

Thakre R, Gharde P, Raghuwanshi M

Cureus 2023; (15(11)):e49313 doi:10.7759/cureus.49313.

Primary Immune Thrombocytopenic Purpura (ITP) and ITP Associated with Systemic Lupus Erythematosus: A Review of Clinical Characteristics and Treatment Modalities.

Bashyal KP, Shah S, Ghimire C, et al.

International journal of rheumatology 2024; (2024()):6650921 doi:10.1155/2024/6650921.

Immune attack on megakaryocytes in immune thrombocytopenia.

Petito E, Gresele P

Research and practice in thrombosis and haemostasis 2024; (8(1)):102345 doi:10.1016/j.rpth.2024.102345.

The 2022 review of the 2019 American Society of Hematology guidelines on immune thrombocytopenia.

Neunert CE, Arnold DM, Grace RF, et al.

Blood advances 2024; (8(13)):3578-3582 doi:10.1182/bloodadvances.2023012541.

Bevacizumab-induced immune thrombocytopenia in an ovarian cancer patient with mixed connective tissue disease: case report and literature review.

Zhang Y, Yang F, Wang J, et al.

Frontiers in immunology 2024; (15()):1382964 doi:10.3389/fimmu.2024.1382964.

Tapering and Sustained Remission of Thrombopoietin Receptor Agonists (TPO-RAs): Is it Time for Paediatric ITP?

Marcos-Peña S, Fernández-Pernia B, Provan D, González-López TJ

Advances in therapy 2024; (41(10)):3771-3777 doi:10.1007/s12325-024-02951-5.

Comprehensive genetic analysis for identification of monogenic disorders and selection of appropriate treatments in pediatric patients with persistent thrombocytopenia.

Sato D, Kirikae H, Nakano T, et al.

Pediatric hematology and oncology 2024; (41(8)):541-556 doi:10.1080/08880018.2024.2395358.

Immune Thrombocytopenic Purpura (ITP) With Ulcerative Colitis (UC).

Mohammed SK, Budamagunta S, Khan WA, et al.

Cureus 2024; (16(10)):e72778 doi:10.7759/cureus.72778.

The role of genetic sequencing in the diagnostic workup for chronic immune thrombocytopenia.

Joshi N, Lango-Allen H, Downes K, et al.

Blood advances 2025; (9(7)):1497-1507 doi:10.1182/bloodadvances.2024014639.

A Case of Eltrombopag-Induced Thrombotic Microangiopathy Initiating Hemodialysis.

Fukuda H, Kitamura M, Sugiyama S, et al.

Cureus 2024; (16(12)):e75947 doi:10.7759/cureus.75947.

[Refractory immune thrombocytopenia revealing MYH9 related disease in a 64-year-old man].

Bodard Q, Fredon G, Riche A, et al.

La Revue de medecine interne 2025; (46(4)):236-239 doi:10.1016/j.revmed.2024.12.005.

Mycobacterium immunogenum-Induced Thrombocytopenia.

Viera A, Wahba P, Vicens J, et al.

Cureus 2025; (17(1)):e78306 doi:10.7759/cureus.78306.

Immune Thrombocytopenia Induced by Helicobacter pylori Infection: A Case Report and Literature Review.

Alrakha A, Kamal N, Sherif W, ElGohary G

Cureus 2025; (17(4)):e82167 doi:10.7759/cureus.82167.

Assessing serum thrombopoietin for enhanced diagnosis of ITP, AA, and MDS using machine learning: A retrospective cohort study.

Zhu G, Ren Y, Wang L, et al.

Annals of hematology 2025; (104(7)):3631-3645 doi:10.1007/s00277-025-06308-y.

A novel variant of MYH9 mutation associated macro-thrombocytopenia: A case series.

Wadhera S, Sharma R, Sahni A, et al.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2025; (64(6)):104254 doi:10.1016/j.transci.2025.104254.

Outcome and response to different management regimens in pediatric patients with immune thrombocytopenia (ITP).

AbdelAziz RA, El-Sayed D, Ahmed FEZ, Komy MA

Annals of hematology 2025; (104(10)):5003-5010 doi:10.1007/s00277-025-06626-1.

Platelet count and sleep quality in immune thrombocytopenia: correlation with 5-hydroxytryptamine and therapeutic implications of platelet-5-HT-melatonin axis dysregulation.

Jiao Y, Fan W, Wang Y, et al.

Frontiers in neurology 2025; (16()):1645796 doi:10.3389/fneur.2025.1645796.

Original Versus Generic Eltrombopag in Patients with Immune Thrombocytopenia: A Prospective Multi-Center Experience on Efficacy and Safety.

Çelik S, Karabulut ZT, Selim C, et al.

Journal of clinical medicine 2026; (15(2)) doi:10.3390/jcm15020634.