Research & Literature

Neurocutaneous melanosis.

Islam MP

Handbook of clinical neurology 2015; (132()):111-7.

Malignant peripheral nerve sheath tumor coexisting with congenital melanocytic nevus in an elderly man.

Park JK, Sugita S, Soma T, et al.

Pathology international 2016; (66(5)):309-10 doi:10.1111/pin.12392.

Proliferative Nodules vs Melanoma Arising in Giant Congenital Melanocytic Nevi During Childhood.

Vergier B, Laharanne E, Prochazkova-Carlotti M, et al.

JAMA dermatology 2016; (152(10)):1147-1151 doi:10.1001/jamadermatol.2016.2667.

Malignant Melanoma in Association With a Thymic Nevus in a Patient With a Giant Congenital Nevus.

Shvartser-Beryozkin Y, Yakobson A, Benharroch D, et al.

The American Journal of dermatopathology 2017; (39(7)):538-541 doi:10.1097/DAD.0000000000000817.

Melanoma in congenital melanocytic naevi.

Kinsler VA, O'Hare P, Bulstrode N, et al.

The British journal of dermatology 2017; (176(5)):1131-1143 doi:10.1111/bjd.15301.

Mass Spectrometry Imaging Can Distinguish on a Proteomic Level Between Proliferative Nodules Within a Benign Congenital Nevus and Malignant Melanoma.

Lazova R, Yang Z, El Habr C, et al.

The American Journal of dermatopathology 2017; (39(9)):689-695 doi:10.1097/DAD.0000000000000849.

Patterns of distribution of giant congenital melanocytic nevi (GCMN): The 6B rule.

Martins da Silva VP, Marghoob A, Pigem R, et al.

Journal of the American Academy of Dermatology 2017; (76(4)):689-694 doi:10.1016/j.jaad.2016.05.042.

Tissue expansion in the treatment of giant congenital melanocytic nevi of the upper extremity.

Ma T, Fan K, Li L, et al.

Medicine 2017; (96(13)):e6358 doi:10.1097/MD.0000000000006358.

Proliferative nodule in melanocytic nevi mimicking deep penetrating nevus.

Almodovar-Real A, Molina-Leyva A, Aneiros-Fernandez J, Diaz-Martinez MA

Anais brasileiros de dermatologia 2017; (92(2)):231-233 doi:10.1590/abd1806-4841.20175383.

Pediatric dermatopathology: an overview.

Afsar FS, Diniz G, Aktas S

Archivos argentinos de pediatria 2017; (115(4)):377-381 doi:10.5546/aap.2017.eng.377.

Spectrum of Clinical, Neuroimaging, and Cerebrospinal Fluid Features of Adult Neurocutaneous Melanocytosis.

Qian M, Ren H, Qu T, et al.

European neurology 2018; (80(1-2)):1-6 doi:10.1159/000488687.

Sedation for screening MRI in patients with congenital melanocytic naevi under the age of one is a successful, safe and economical first-line approach.

Plumptre I, Stuart G, Cerullo A, Kinsler VA

The British journal of dermatology 2019; (180(3)):668-669 doi:10.1111/bjd.17263.

Genetic Abnormalities in Large to Giant Congenital Nevi: Beyond NRAS Mutations.

Martins da Silva V, Martinez-Barrios E, Tell-Martí G, et al.

The Journal of investigative dermatology 2019; (139(4)):900-908 doi:10.1016/j.jid.2018.07.045.

Proliferating Neurocristic Hamartoma Arising in a Giant Congenital Nevus: Comparative Genomic Hybridization Findings.

Garrido MC, Maroñas-Jiménez L, Ruano Y, Rodriguez-Peralto JL

The American Journal of dermatopathology 2019; (41(6)):438-442 doi:10.1097/DAD.0000000000001319.

Serial Excision for the Treatment of Giant Congenital Melanocytic Nevus: The Vietnamese Way.

Hong SN, Huu ND, Duy NN, et al.

Open access Macedonian journal of medical sciences 2019; (7(2)):231-233 doi:10.3889/oamjms.2019.058.

Melanoma arising in a Giant congenital melanocytic nevus: two case reports.

Belysheva TS, Vishnevskaya YV, Nasedkina TV, et al.

Diagnostic pathology 2019; (14(1)):21 doi:10.1186/s13000-019-0797-1.

Neurocutaneous Melanosis in Association With Large Congenital Melanocytic Nevi in Children: A Report of 2 Cases With Clinical, Radiological, and Pathogenetic Evaluation.

Chen L, Zhai L, Al-Kzayer LFY, et al.

Frontiers in neurology 2019; (10()):79 doi:10.3389/fneur.2019.00079.

Management of Congenital Melanocytic Nevus on Face Using Multiple Re-expansion Method: Aesthetic and Psychosocial Results.

Lee H, Eom Y, Oh KS

The Journal of craniofacial surgery 2019; (30(8)):2385-2389 doi:10.1097/SCS.0000000000006000.

Giant congenital melanocytic nevi.

Escandón-Pérez S, Landeta-Sa AP, González-Jasso Y, Arenas-Guzmán R

Boletin medico del Hospital Infantil de Mexico 2019; (76(6)):251-258 doi:10.24875/BMHIM.18000103.

The outcome of using different surgical modalities and laser therapy in the treatment of small- and medium-sized congenital melanocytic nevi: a systematic review.

ALMutairi HM, Al-Hothali GI

International journal of dermatology 2020; (59(5)):535-542 doi:10.1111/ijd.14727.

Skin-related quality of life in children and adolescents with congenital melanocytic naevi - an analysis of self- and parent reports.

Neuhaus K, Landolt MA, Theiler M, et al.

Journal of the European Academy of Dermatology and Venereology : JEADV 2020; (34(5)):1105-1111 doi:10.1111/jdv.16131.

A large-scale collection of giant congenital melanocytic nevi: Clinical and histopathological characteristics.

Wu M, Yu Q, Gao B, et al.

Experimental and therapeutic medicine 2020; (19(1)):313-318 doi:10.3892/etm.2019.8198.

Pemphigus vulgaris possibly associated with application of a tissue expander in a patient with Crohn's disease and primary sclerosing cholangitis.

Badavanis G, Pasmatzi E, Kapranos N, et al.

Acta dermatovenerologica Alpina, Pannonica, et Adriatica 2019; (28(4)):173-176.

Congenital melanocytic nevi.

Moustafa D, Blundell AR, Hawryluk EB

Current opinion in pediatrics 2020; (32(4)):491-497 doi:10.1097/MOP.0000000000000924.

Neurocutaneous melanocytosis (melanosis).

Ruggieri M, Polizzi A, Catanzaro S, et al.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2020; (36(10)):2571-2596 doi:10.1007/s00381-020-04770-9.

Cutaneous Melanoma Arising in Congenital Melanocytic Nevus: A Retrospective Observational Study.

Caccavale S, Calabrese G, Mattiello E, et al.

Dermatology (Basel, Switzerland) 2021; (237(3)):473-478 doi:10.1159/000510221.

Diagnostic uncertainty in pediatric chronic pain: nature, prevalence, and consequences.

Neville A, Jordan A, Pincus T, et al.

Pain reports 2020; (5(6)):e871 doi:10.1097/PR9.0000000000000871.

Surgical outcomes and psychosocial impact of giant congenital melanocytic nevus surgery: A single-center case series of 136 patients.

Carmen Ceballos-Rodríguez M, Redondo P, Tomás-Velázquez A, et al.

Journal of pediatric surgery 2021; (56(11)):2113-2117 doi:10.1016/j.jpedsurg.2020.12.023.

Congenital melanocytic naevi: An up-to-date overview.

Farabi B, Akay BN, Goldust M, et al.

The Australasian journal of dermatology 2021; (62(2)):e178-e191 doi:10.1111/ajd.13535.

Assessing comfort level with pediatric skin specimens among dermatopathologists and pediatric pathologists: A national cross-sectional survey.

Enos T, Hughes C, Kelley S, et al.

Journal of cutaneous pathology 2021; (48(9)):1109-1114 doi:10.1111/cup.13997.

Distribution Patterns (7B Rule) and Characteristics of Large Congenital Melanocytic Nevi: A Retrospective Cohort Study in China.

Wang H, Wang W, Lu J, et al.

Frontiers in medicine 2021; (8()):637857 doi:10.3389/fmed.2021.637857.

Giant Congenital Melanocytic Nevus in a Chinese Newborn.

Lin W, Zhou Y, Li R

Clinical, cosmetic and investigational dermatology 2021; (14()):557-559 doi:10.2147/CCID.S308725.

A Case of Giant Congenital Melanocytic Nevus Treated with Combination Therapy of Autologous Mesh-skin Grafts and Cultured Epithelial Autografts.

Im S, Yamanaka H, Tsuge I, et al.

Plastic and reconstructive surgery. Global open 2021; (9(6)):e3613 doi:10.1097/GOX.0000000000003613.

Giant Congenital Melanocytic Nevi in a Pakistani Newborn.

Mumtaz Hashmi H, Shamim N, Kumar V, Idrees S

Cureus 2021; (13(5)):e15210 doi:10.7759/cureus.15210.

Psychosocial Experiences in Children With Congenital Melanocytic Nevus on the Face and Their Parents Throughout the Tissue Expansion Treatment.

Zhang C, Wu L, Zhao S, et al.

The Journal of craniofacial surgery 2022; (33(3)):754-758 doi:10.1097/SCS.0000000000008151.

The retrospective molecular analysis of large or giant congenital melanocytic nevi in a group of Polish children.

Wertheim-Tysarowska K, Szczygielski O, Seliga K, et al.

Journal of mother and child 2021; (25(1)):19-24 doi:10.34763/jmotherandchild.20212501.d-21-00007.

Quality of Life in Chinese Patients With Large Congenital Melanocytic Nevi.

Wang H, Yu Q, Li Q, Wang Z

Frontiers in pediatrics 2022; (10()):784660 doi:10.3389/fped.2022.784660.

Neurosurgical management of patients with neurocutaneous melanosis: a systematic review.

Rahman RK, Majmundar N, Ghani H, et al.

Neurosurgical focus 2022; (52(5)):E8 doi:10.3171/2022.2.FOCUS21791.

A case of proliferative nodule arising within blue nevus.

Proietti I, Skroza N, Michelini S, et al.

La Clinica terapeutica 2022; (173(3)):214-216 doi:10.7417/CT.2022.2420.

Diagnostic uncertainty in patients, parents, and physicians: a compensatory control theory perspective.

McKoane A, Sherman DK

Health psychology review 2023; (17(3)):439-455 doi:10.1080/17437199.2022.2086899.

Evaluation of Biopsy Results, Consultations, and Follow-Ups in Pediatric Dermatopathology.

Manav V, Döş YM, Erdil D, Koku Aksu AE

Turkish archives of pediatrics 2022; (57(5)):544-550 doi:10.5152/TurkArchPediatr.2022.21342.

Risk of melanoma in congenital melanocytic nevi of all sizes: A systematic review.

Scard C, Aubert H, Wargny M, et al.

Journal of the European Academy of Dermatology and Venereology : JEADV 2023; (37(1)):32-39 doi:10.1111/jdv.18581.

Serial excision surgery for giant dorsal congenital melanocytic nevus: Case report.

Dung PTV, Son TT, Thuy TTH, Duy TT

International journal of surgery case reports 2023; (106()):108152 doi:10.1016/j.ijscr.2023.108152.

Giant Congenital Melanocytic Nevus of the Male External Genitalia: A Pediatric Case Report of Diagnosis, Evaluation and Management.

Donnenfeld SR, Lovin JM, Santore MT, et al.

Urology 2023; (181()):147-149 doi:10.1016/j.urology.2023.08.004.

Mosaic BRAF Fusions Are a Recurrent Cause of Congenital Melanocytic Nevi Targetable by MAPK Pathway Inhibition.

Martin SB, Polubothu S, Bruzos AL, et al.

The Journal of investigative dermatology 2024; (144(3)):593-600.e7 doi:10.1016/j.jid.2023.06.213.

Updates in the Management of Congenital Melanocytic Nevi.

Mologousis MA, Tsai SY, Tissera KA, et al.

Children (Basel, Switzerland) 2024; (11(1)) doi:10.3390/children11010062.

Prevalence, incidence density and standardized morbidity rate of melanoma among patients with congenital melanocytic naevi: a systematic review.

Tan S, Hu H, Li G, et al.

Clinical and experimental dermatology 2024; (49(8)):765-773 doi:10.1093/ced/llae056.

Thickness of melanocytes in giant congenital melanocytic nevus for complete surgical excision: clinicopathological evaluation of 117 lesions according to the area and size.

Kim JY, Lee SY, Kwak Y, Kim BJ

BMC surgery 2024; (24(1)):90 doi:10.1186/s12893-024-02362-x.

Melanoma on congenital melanocytic nevi.

Alos L, Carrasco A, Teixidó C, et al.

Pathology, research and practice 2024; (256()):155262 doi:10.1016/j.prp.2024.155262.

Serial tissue expansion and excision for reconstruction of giant dorsal congenital melanocytic nevus: A case report.

Le HP, Tran NT, Nguyen Tran BS, Le NTN

SAGE open medical case reports 2024; (12()):2050313X241275330 doi:10.1177/2050313X241275330.

Congenital melanocytic nevi and risk of melanoma.

Pastore LM, Valentini R, Marghoob AA

Clinics in dermatology 2025; (43(3)):378-384 doi:10.1016/j.clindermatol.2024.09.004.

Congenital melanocytic nevus syndrome: An association between congenital melanocytic nevi and neurological abnormalities.

Ruth J

Seminars in pediatric neurology 2024; (51()):101153 doi:10.1016/j.spen.2024.101153.

Spinal Neurocutaneous Melanosis.

Demartini Z, Maeda AK, Cardoso-Demartini A

World neurosurgery 2025; (193()):100-101 doi:10.1016/j.wneu.2024.10.050.

Isolated melanoma metastasis in a patient with large congenital nevus without detectable primary melanoma: a case report and review of literature.

Pabianek M, Jatczak-Grochala I, Lesiak A, et al.

Frontiers in medicine 2024; (11()):1427982 doi:10.3389/fmed.2024.1427982.

Neurocutaneous Melanocytosis-Associated Hydrocephalus: The Memorial Sloan Kettering Experience from 2001 to 2022.

Rodriguez S, DeIeso-Frechette F, Umeasor C, et al.

Pediatric blood & cancer 2025; (72(1)):e31434 doi:10.1002/pbc.31434.

Central Nervous System Involvement and Neuroradiological Imaging Insights of Neurocutaneous Melanocytosis in Congenital Melanocytic Nevi.

Ruff C, Gohla G, Nägele T, Batra M

Diagnostics (Basel, Switzerland) 2024; (14(21)) doi:10.3390/diagnostics14212345.

Case Report: Prenatal ultrasound presentation of congenital melanocytic nevus syndrome.

Shi Z, Sun T, Yin J, et al.

Frontiers in pediatrics 2024; (12()):1466999 doi:10.3389/fped.2024.1466999.

Congenital Melanocytic Nevi.

Nathan S, Smetona J, Naran S, Bauer BS

Clinics in plastic surgery 2025; (52(2)):259-269 doi:10.1016/j.cps.2024.09.003.

Real-world pharmacokinetics of trametinib in pediatric low-grade glioma.

Pagnot L, Granger I, Guitton J, et al.

Cancer chemotherapy and pharmacology 2025; (95(1)):35 doi:10.1007/s00280-025-04761-0.

A successful serial excision surgery for congenital melanocytic nevus in a child: A case report.

Al Sakka Amini R, Hakmi A, Hendi H, et al.

International journal of surgery case reports 2025; (130()):111297 doi:10.1016/j.ijscr.2025.111297.

Targeted treatment of hypophosphatemia with trametinib in HRAS-related mosaic RASopathy.

Mirza A, Rossi C, Kulozik A, et al.

Orphanet journal of rare diseases 2025; (20(1)):339 doi:10.1186/s13023-025-03801-5.

Social support and quality of life in Chinese heart transplant recipients: mediation through uncertainty in illness and moderation by psychological resilience.

Gao C, Gui S, Zhu L, et al.

Frontiers in psychiatry 2025; (16()):1637110 doi:10.3389/fpsyt.2025.1637110.

Personalized surveillance in giant congenital melanocytic nevus, including the role of AI, histopathology and MC1R genotyping: A case report.

Vasilev P, Yordanova I, Popovska S, Kamburova Z

Biomedical reports 2026; (24(3)):34 doi:10.3892/br.2026.2107.

Aggressive infantile melanoma arising in a congenital nevus with rare BRAF and BCOR mutations: a case report and literature review of pediatric melanoma.

Mordechai O, Ofir H, Leitner O, et al.

Dermatology reports 2026; doi:10.4081/dr.2026.10470.

Impaired Bone Healing and Fracture Complications during Limb Lengthening in a Neurofibromatosis Type 1 Patient Receiving Selumetinib: Case Report and Literature Review.

Safari Z, Tirta M, Rahbek O, Kold S

Journal of orthopaedic case reports 2026; (16(2)):221-227 doi:10.13107/jocr.2026.v16.i02.6810.

Diagnostic Utility of PRAME and H3K27me3 in Distinguishing Malignant Melanoma From Proliferative Nodules on Congenital Melanocytic Nevi.

Hurdogan O, Baykal C, Yilmaz İ, et al.

Journal of cutaneous pathology 2026; (53(8)):749-755 doi:10.1111/cup.70119.

Melanoma Arising in a Medium-Sized Congenital Melanocytic Nevus: A Case Report.

Nishimura K, Yamamura Y, Usui S, et al.

Cureus 2026; (18(5)):e109026 doi:10.7759/cureus.109026.