Research & Literature

Invasive Fusobacterium necrophorum infections and Lemièrre's syndrome: the role of thrombophilia and EBV.

Holm K, Svensson PJ, Rasmussen M

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2015; (34(11)):2199-207 doi:10.1007/s10096-015-2469-8.

Diplopia as a sequel of unilateral neck dissection.

Gupta MP, Sagar P, Hota A, et al.

Head & neck 2016; (38(8)):E2475-8 doi:10.1002/hed.24428.

Fusobacterium necrophorum findings in Denmark from 2010 to 2014 using data from the Danish microbiology database.

Bank S, Jensen A, Nielsen HM, et al.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2016; (124(12)):1087-1092 doi:10.1111/apm.12606.

Coexisting pulmonary haemorrhage and venous thrombosis: a tricky but novel case.

Fielding A, Pecheva M, Farghal A, Phillips R

BMJ case reports 2016; (2016()) doi:10.1136/bcr-2016-217168.

Three variants of the leukotoxin gene in human isolates of Fusobacterium necrophorum subspecies funduliforme.

Holm K, Collin M, Hagelskjær-Kristensen L, et al.

Anaerobe 2017; (45()):129-132 doi:10.1016/j.anaerobe.2017.03.016.

Delayed Migration and Perforation of the Jugular Vein by a Peripherally Inserted Central Catheter.

Oliver JJ, Connor RE, Powell JR, et al.

Clinical practice and cases in emergency medicine 2017; (1(4)):384-386 doi:10.5811/cpcem.2017.9.35829.

Lemierre Syndrome: Clinical Update and Protocol for a Systematic Review and Individual Patient Data Meta-analysis.

Sacco C, Zane F, Granziera S, et al.

Hamostaseologie 2019; (39(1)):76-86 doi:10.1055/s-0038-1654720.

Diplopia-an unheralded consequence of neck dissection: case report.

Nagarkar R, Kokane G, Wagh A, Roy S

Oral and maxillofacial surgery 2018; (22(3)):341-343 doi:10.1007/s10006-018-0711-0.

Lemierre's syndrome: a disguised threat.

Alves S, Stella L, Carvalho I, Moreira D

BMJ case reports 2019; (12(4)) doi:10.1136/bcr-2018-228397.

Lemierre's Syndrome Caused by Streptococcus anginosus Presenting as Postseptal Cellulitis in a Pediatric Patient.

Camacho-Cruz J, Preciado H, Beltrán N, et al.

ORL; journal for oto-rhino-laryngology and its related specialties 2019; (81(4)):234-239 doi:10.1159/000500560.

[A sepsis that you don't expect… Lemierre's syndrome. Description of a clinical case.]

Dal Bo S, Calandriello L, Biserna L, et al.

Recenti progressi in medicina 2019; (110(11)):543-547 doi:10.1701/3265.32329.

Invasive infections with Fusobacterium necrophorum including Lemierre's syndrome: an 8-year Swedish nationwide retrospective study.

Nygren D, Holm K

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2020; (26(8)):1089.e7-1089.e12 doi:10.1016/j.cmi.2019.12.002.

Cavernous sinus thrombosis caused by Streptococcus constellatus-associated Lemierre syndrome presenting as an isolated abducens nerve palsy.

Rohowetz LJ, Gratton SM, Dansdill D, et al.

American journal of ophthalmology case reports 2020; (18()):100592 doi:10.1016/j.ajoc.2020.100592.

Lemierre syndrome caused by Klebsiella pneumoniae complicated by epidural abscess - Case report.

Sabaka P, Kachlíková M, Bendžala M, Káčerová H

IDCases 2020; (19()):e00664 doi:10.1016/j.idcr.2019.e00664.

Diagnosis and Management of Lemierre's Syndrome Presented with Multifocal Pneumonia and Cerebral Venous Sinus Thrombosis.

Sattar Y, Susheela AT, Karki B, et al.

Case reports in infectious diseases 2020; (2020()):6396274 doi:10.1155/2020/6396274.

Patients with Lemierre syndrome have a high risk of new thromboembolic complications, clinical sequelae and death: an analysis of 712 cases.

Valerio L, Zane F, Sacco C, et al.

Journal of internal medicine 2021; (289(3)):325-339 doi:10.1111/joim.13114.

[Cervicofacial cellulitis complicated by internal jugular vein thrombosis].

Bonné E, Pourcelet A, Del Marmol V, Couturier B

Annales de dermatologie et de venereologie 2020; (147(10)):643-647 doi:10.1016/j.annder.2020.04.013.

Lemierre Syndrome: A Meta-analysis.

Gore MR

International archives of otorhinolaryngology 2020; (24(3)):e379-e385 doi:10.1055/s-0039-3402433.

A Rare Case Report of Lemierre Syndrome from the Anterior Jugular Vein.

Rejali N, Heyer M, Finefrock D

Clinical practice and cases in emergency medicine 2020; (4(3)):454-457 doi:10.5811/cpcem.2020.7.47442.

A Case of Lemierre Syndrome in the Era of COVID-19: All That Glitters Is Not Gold.

Repper DC, Arrieta AC, Cook JE, Renella P

The Pediatric infectious disease journal 2020; (39(12)):e445-e447 doi:10.1097/INF.0000000000002939.

Lemierre syndrome: Current evidence and rationale of the Bacteria-Associated Thrombosis, Thrombophlebitis and LEmierre syndrome (BATTLE) registry.

Valerio L, Corsi G, Sebastian T, Barco S

Thrombosis research 2020; (196()):494-499 doi:10.1016/j.thromres.2020.10.002.

Lemierre's syndrome or re-emerging disease: Case report and literature review.

Chaker K, Berrada O, Lyoubi M, et al.

International journal of surgery case reports 2021; (78()):151-154 doi:10.1016/j.ijscr.2020.12.015.

Lemierre Syndrome: Unusual Presentation With Superior Ophthalmic Vein Thrombosis.

Caruso DP, Peacock ZS

The Journal of craniofacial surgery 2021; (32(3)):1079-1082 doi:10.1097/SCS.0000000000007363.

Jugular Vein Thrombosis and Anticoagulation Therapy in Lemierre's Syndrome-A Post Hoc Observational and Population-Based Study of 82 Patients.

Nygren D, Elf J, Torisson G, Holm K

Open forum infectious diseases 2021; (8(1)):ofaa585 doi:10.1093/ofid/ofaa585.

Forget-me-not: Lemierre's syndrome, a case report.

Silverberg B, Sharon MJ, Makati D, et al.

Journal of American college health : J of ACH 2023; (71(2)):343-347 doi:10.1080/07448481.2021.1899190.

Prevalence and Clinical Characteristics of Patients With Sepsis Discharge Diagnosis Codes and Short Lengths of Stay in U.S. Hospitals.

Kuye I, Anand V, Klompas M, et al.

Critical care explorations 2021; (3(3)):e0373 doi:10.1097/CCE.0000000000000373.

Ophthalmic complications of Lemierre syndrome.

Kreuzpointner R, Valerio L, Corsi G, et al.

Acta ophthalmologica 2022; (100(1)):e314-e320 doi:10.1111/aos.14871.

Management of Lemierre Syndrome.

Valerio L, Pleming W, Pecci A, Barco S

Minerva medica 2021; (112(6)):726-739 doi:10.23736/S0026-4806.21.07497-8.

An unusual case of Lemierre syndrome - One pathogen or two?

O'Shaughnessy M, Irizarry D, Finkel D

IDCases 2021; (25()):e01203 doi:10.1016/j.idcr.2021.e01203.

Lemierre Syndrome in a Patient With Splenectomy Secondary to Pyruvate Kinase Deficiency, Complicated by Heparin Resistance.

Clark K, Sly M, Chan P, et al.

Journal of investigative medicine high impact case reports 2021; (9()):23247096211040635 doi:10.1177/23247096211040635.

Lemierre's Syndrome: A Case of Life-Threatening Infection From Family Medicine Practice.

Gohal SO, Alsubhi IM, Alharbi EA, et al.

Cureus 2021; (13(12)):e20684 doi:10.7759/cureus.20684.

[Suppurative Thrombophlebitis of the Posterior Neck Caused by Streptococcus constellatus: A Case Report and Literature Review].

Takada K, Nakamura M, Samura M, et al.

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2022; (142(2)):189-193 doi:10.1248/yakushi.21-00179.

Factors Affecting Patients with Concurrent Deep Neck Infection and Lemierre's Syndrome.

Chen SL, Chin SC, Wang YC, Ho CY

Diagnostics (Basel, Switzerland) 2022; (12(4)) doi:10.3390/diagnostics12040928.

Use of intravascular hypo- and hyper-attenuation on non-contrast-enhanced computed tomography in diagnosing acute septic thrombophlebitis.

Yoshikawa S, Ueda T, Fujiwara T

Journal of radiology case reports 2022; (16(3)):1-14 doi:10.3941/jrcr.v16i3.4364.

Fusobacterium necrophorum Promotes Apoptosis and Inflammatory Cytokine Production Through the Activation of NF-κB and Death Receptor Signaling Pathways.

Wang FF, Zhao PY, He XJ, et al.

Frontiers in cellular and infection microbiology 2022; (12()):827750 doi:10.3389/fcimb.2022.827750.

Lemierre's syndrome with cranial epidural abscess complication: A case report.

Ibrahim IG, Osman AA, Elmi AM, et al.

Annals of medicine and surgery (2012) 2022; (81()):104478 doi:10.1016/j.amsu.2022.104478.

Atypical involvement of the thyro-linguo-facial vein in Lemierre syndrome.

Constans S, Bosshard T, Petignat PA, Le Peillet D

BMJ case reports 2022; (15(11)) doi:10.1136/bcr-2022-251722.

Lemierre's Syndrome: A Case Report.

Santos L, Monteiro F, Marques M, et al.

Cureus 2023; (15(1)):e34473 doi:10.7759/cureus.34473.

Lemierre syndrome: a hidden complication of sore throats.

AlAmer NA, AlMarzouq WF

International journal of emergency medicine 2023; (16(1)):45 doi:10.1186/s12245-023-00524-x.

Lemierre Syndrome Complicated by Emphysematous Osteomyelitis.

Cotton JJ, Lang FM, Onyilofor C, et al.

Cureus 2023; (15(8)):e43719 doi:10.7759/cureus.43719.

Lemierre's Syndrome Under the Disguise of COVID-19 Pneumonia: A Case Report and Systematic Review.

Zhang Y, Zeng Y

Cureus 2023; (15(9)):e45827 doi:10.7759/cureus.45827.

Case report: Metagenomics next-generation sequencing in the diagnosis of septic shock due to Fusobacterium necrophorum in a 6-year-old child.

Zhang H, Liu Z, Guan Y, et al.

Frontiers in cellular and infection microbiology 2024; (14()):1236630 doi:10.3389/fcimb.2024.1236630.

Pediatric Lemierre's Syndrome: A Comprehensive Literature Review.

Lavalle S, Masiello E, Cocuzza S, et al.

Pediatric reports 2024; (16(1)):201-213 doi:10.3390/pediatric16010018.

Uncommon Culprit, Familiar Foe: A Case of Septic Thrombophlebitis of the Internal Jugular Vein Triggered by Klebsiella Bacteremia.

Yetiskul E, Agarwal A, Khan S, et al.

Cureus 2024; (16(3)):e56716 doi:10.7759/cureus.56716.

Surgical intervention of Lemierre's syndrome: a case report and review of the literature.

Pan Y, Shi Z, Ye B, et al.

Journal of medical case reports 2024; (18(1)):265 doi:10.1186/s13256-024-04584-2.

Lemierre Syndrome in the Setting of Bacteremia and Atypical Pneumonia: A Case Report.

Walizada AS, Lyons SE, Penales C, Lopez-Medal MA

Cureus 2024; (16(9)):e69178 doi:10.7759/cureus.69178.

Point-of-care ultrasound for Lemierre's syndrome during the COVID-19 pandemic: A case report.

Kawai Y, Nishiyama K

Journal of general and family medicine 2024; (25(5)):274-276 doi:10.1002/jgf2.708.

Early Radiographic Warning Signs of Impending Lemierre's Syndrome.

Nathan RS, Ostrowski TJ, Narayan A, Gildener-Leapman N

Cureus 2024; (16(12)):e75976 doi:10.7759/cureus.75976.

Bacteria and host: what does this mean for sepsis bottleneck?

Alharbi AS, Sanyi RH, Azhar EI

World journal of emergency medicine 2025; (16(1)):10-17 doi:10.5847/wjem.j.1920-8642.2025.001.

Internal Jugular Vein Reconstruction with Cephalic Vein Interposition Graft: A Case Report and Review of Literature.

Chavan P, B GK, Upadhya G, et al.

Indian journal of surgical oncology 2025; (16(1)):198-202 doi:10.1007/s13193-024-02063-0.

Nasal Venous Malformation with Intracranial Communication: Presentation, Management, and Review of the Literature.

Messa GE, Nachabe AM, Sheahan C, et al.

The Journal of craniofacial surgery 2025; doi:10.1097/SCS.0000000000011694.

Eventual resolution of pulmonary cavities following septic pulmonary embolism secondary to right-sided infective endocarditis.

Ogata T, Takahashi S, Moriya T, Yamashita T

BMJ case reports 2025; (18(8)) doi:10.1136/bcr-2025-267535.

Uncommon manifestation of invasive group A Streptococcus infection: Lemierre syndrome with multiple pulmonary complications.

Cheng BYC, Gallant RC, Bell C, Priel E

BMJ case reports 2025; (18(8)) doi:10.1136/bcr-2025-265839.

From Resuscitation to Rehabilitation: The Post-Intensive Care Syndrome Continuum in Sepsis Care.

Sherman M, Lim P, Cheema T, et al.

Journal of clinical medicine 2025; (14(23)) doi:10.3390/jcm14238374.

Lemierre's Syndrome Caused by Klebsiella pneumoniae: Case Report and Review of the Literature.

Guerrero AA, Rosales EP

Clinical case reports 2026; (14(2)):e72003 doi:10.1002/ccr3.72003.