Research & Literature

Donning devices (foot slips and frames) enable elderly people with severe chronic venous insufficiency to put on compression stockings.

Sippel K, Seifert B, Hafner J

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2015; (49(2)):221-9.

Liver enzymes and lipid levels in patients with lipodermatosclerosis and venous ulcers treated with a prototypic anabolic steroid (stanozolol): a prospective, randomized, double-blinded, placebo-controlled trial.

Carson P, Hong CJ, Otero-Vinas M, et al.

The international journal of lower extremity wounds 2015; (14(1)):11-8 doi:10.1177/1534734614562276.

MECHANISMS IN ENDOCRINOLOGY: Medical consequences of doping with anabolic androgenic steroids: effects on reproductive functions.

Nieschlag E, Vorona E

European journal of endocrinology 2015; (173(2)):R47-58 doi:10.1530/EJE-15-0080.

Chronic venous disease and venous leg ulcers: An evidence-based update.

Kelechi TJ, Johnson JJ, Yates S

Journal of vascular nursing : official publication of the Society for Peripheral Vascular Nursing 2015; (33(2)):36-46.

Non-HIV-related Kaposi sarcoma in 2 Hispanic patients arising in the setting of chronic venous insufficiency.

Que SK, DeFelice T, Abdulla FR, et al.

Cutis 2015; (95(6)):E30-3.

Combined treatment with endovenous laser ablation and compression therapy of incompetent perforating veins for treatment of recalcitrant venous ulcers.

Seren M, Dumantepe M, Fazliogullari O, Kucukaksu S

Phlebology 2017; (32(5)):307-315 doi:10.1177/0268355515594075.

Lipodermatosclerosis: a clinicopathologic correlation.

Choonhakarn C, Chaowattanapanit S, Julanon N

International journal of dermatology 2016; (55(3)):303-8 doi:10.1111/ijd.12856.

Medical management of venous ulcers.

Pascarella L, Shortell CK

Seminars in vascular surgery 2015; (28(1)):21-8.

Bilateral cellulitis.

Batra V, Baras A

BMJ case reports 2015; (2015()).

A Compression Kit of a Stocking and Three Superimposed Leggings Is Easy to Don and Dose Adjustable.

Luder C, Dziunycz P, Omid N, et al.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2016; (51(3)):434-40.

Modalities to Treat Venous Ulcers: Compression, Surgery, and Bioengineered Tissue.

Gould LJ, Dosi G, Couch K, et al.

Plastic and reconstructive surgery 2016; (138(3 Suppl)):199S-208S doi:10.1097/PRS.0000000000002677.

Compression therapy in patients with venous leg ulcers.

Dissemond J, Assenheimer B, Bültemann A, et al.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2016; (14(11)):1072-1087 doi:10.1111/ddg.13091.

Stasis Dermatitis: Pathophysiology, Evaluation, and Management.

Sundaresan S, Migden MR, Silapunt S

American journal of clinical dermatology 2017; (18(3)):383-390 doi:10.1007/s40257-016-0250-0.

[Ulcers in obesity-associated chronic venous insufficiency].

Scholl L, Dörler M, Stücker M

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 2017; (68(7)):560-565 doi:10.1007/s00105-017-3971-y.

Compression therapy for venous leg ulcers: risk factors for adverse events and complications, contraindications - a review of present guidelines.

Andriessen A, Apelqvist J, Mosti G, et al.

Journal of the European Academy of Dermatology and Venereology : JEADV 2017; (31(9)):1562-1568 doi:10.1111/jdv.14390.

Pathophysiology of venous ulceration.

Crawford JM, Lal BK, Durán WN, Pappas PJ

Journal of vascular surgery. Venous and lymphatic disorders 2017; (5(4)):596-605 doi:10.1016/j.jvsv.2017.03.015.

Effects of isokinetic calf muscle exercise program on muscle strength and venous function in patients with chronic venous insufficiency.

Ercan S, Çetin C, Yavuz T, et al.

Phlebology 2018; (33(4)):261-266 doi:10.1177/0268355517695401.

A Randomized Trial of Early Endovenous Ablation in Venous Ulceration.

Gohel MS, Heatley F, Liu X, et al.

The New England journal of medicine 2018; (378(22)):2105-2114 doi:10.1056/NEJMoa1801214.

Symptoms Associated With Chronic Venous Disease in Response to a Cooling Treatment Compared to Placebo: A Randomized Clinical Trial.

Kelechi TJ, Dooley MJ, Mueller M, et al.

Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society 2018; (45(4)):301-309 doi:10.1097/WON.0000000000000441.

A case of gemcitabine-related acute lipodermatosclerosis.

Nyckowski T, McGregor S, Huang WW

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 2019; (25(5)):1271-1274 doi:10.1177/1078155218788709.

Chronic venous insufficiency: a new concept to understand pathophysiology at the microvascular level - a pilot study.

Mutlak O, Aslam M, Standfield NJ

Perfusion 2019; (34(1)):84-89 doi:10.1177/0267659118791682.

Late-onset extensive haematoma mimicking cellulitis.

Baek YS, Song JY, Jeong KM, Jeon J

International wound journal 2019; (16(1)):297-299 doi:10.1111/iwj.13014.

Compression therapy after invasive treatment of superficial veins of the lower extremities: Clinical practice guidelines of the American Venous Forum, Society for Vascular Surgery, American College of Phlebology, Society for Vascular Medicine, and International Union of Phlebology.

Lurie F, Lal BK, Antignani PL, et al.

Journal of vascular surgery. Venous and lymphatic disorders 2019; (7(1)):17-28 doi:10.1016/j.jvsv.2018.10.002.

The diagnosis of infection in chronic leg ulcers: A narrative review on clinical practice.

Bui UT, Finlayson K, Edwards H

International wound journal 2019; (16(3)):601-620 doi:10.1111/iwj.13069.

Prevalence, risk factors, and evaluation of iliocaval obstruction in advanced chronic venous insufficiency.

Sermsathanasawadi N, Pruekprasert K, Pitaksantayothin W, et al.

Journal of vascular surgery. Venous and lymphatic disorders 2019; (7(3)):441-447 doi:10.1016/j.jvsv.2018.10.021.

Compression Therapy Using Bandages Successfully Manages Acute or Subacute Lipodermatosclerosis.

Suehiro K, Morikage N, Harada T, et al.

Annals of vascular diseases 2019; (12(1)):77-79 doi:10.3400/avd.cr.18-00135.

Deep vein thrombosis: update on diagnosis and management.

Kruger PC, Eikelboom JW, Douketis JD, Hankey GJ

The Medical journal of Australia 2019; (210(11)):516-524 doi:10.5694/mja2.50201.

Venous Ulcers: Diagnosis and Treatment.

Bonkemeyer Millan S, Gan R, Townsend PE

American family physician 2019; (100(5)):298-305.

Better wearing comfort of knee-length elastic compression stockings with an interface pressure of 18-21 mmHg compared to 23-32 mmHg in elderly people after a one day trial - Influence on foot deformities, rheumatism and arthritis.

Goetz J, Kaisermayer E, Haase H, et al.

Clinical hemorheology and microcirculation 2019; (73(1)):145-156 doi:10.3233/CH-199207.

A scoping review on Chronic Venous Disease and the development of a Venous Leg Ulcer: The role of obesity and mobility.

Meulendijks AM, Franssen WMA, Schoonhoven L, Neumann HAM

Journal of tissue viability 2020; (29(3)):190-196 doi:10.1016/j.jtv.2019.10.002.

Oxandrolone for treatment of lipodermatosclerosis: case report.

Péret LA, Vidal HM, Gomes GAC, et al.

Jornal vascular brasileiro 2019; (18()):e20190031 doi:10.1590/1677-5449.190031.

Vascular assessment in venous leg ulcer diagnostics and management in Australian primary care: Clinician experiences.

Weller C, Richards C, Turnour L, et al.

Journal of tissue viability 2020; (29(3)):184-189 doi:10.1016/j.jtv.2019.12.005.

Surrounding skin management in venous leg ulcers: A systematic review.

Dini V, Janowska A, Oranges T, et al.

Journal of tissue viability 2020; (29(3)):169-175 doi:10.1016/j.jtv.2020.02.004.

Pentoxifylline for intermittent claudication.

Broderick C, Forster R, Abdel-Hadi M, Salhiyyah K

The Cochrane database of systematic reviews 2020; (10()):CD005262 doi:10.1002/14651858.CD005262.pub4.

Diagnosis and Treatment of Lower Extremity Venous Thromboembolism: A Review.

Chopard R, Albertsen IE, Piazza G

JAMA 2020; (324(17)):1765-1776 doi:10.1001/jama.2020.17272.

Comparative efficacy and safety of traditional Chinese medicine for lipodermatosclerosis: A protocol for systematic review and network meta-analysis.

Du M, Zhang Y, Shi X, Liu M

Medicine 2020; (99(47)):e23386 doi:10.1097/MD.0000000000023386.

Nrf2-activating Therapy Accelerates Wound Healing in a Model of Cutaneous Chronic Venous Insufficiency.

Kuhn J, Sultan DL, Waqas B, et al.

Plastic and reconstructive surgery. Global open 2020; (8(11)):e3006 doi:10.1097/GOX.0000000000003006.

The use of high-frequency skin ultrasound in the diagnosis of lipodermatosclerosis.

Woźniak W, Danowska A, Mlosek RK

Journal of ultrasonography 2021; (20(83)):e284-e290 doi:10.15557/JoU.2020.0050.

Modified compression therapy in mixed arterial-venous leg ulcers: An integrative review.

Lim SLX, Chung RE, Holloway S, Harding KG

International wound journal 2021; (18(6)):822-842 doi:10.1111/iwj.13585.

[Non-Necrotizing Acute Dermo-Hypodermal Infections: Erysipela and Infectious Cellulitis].

Rodrigues MA, Caetano M, Amorim I, Selores M

Acta medica portuguesa 2021; (34(3)):217-228 doi:10.20344/amp.12642.

Immune Checkpoint Inhibition in Marjolin Ulcer: A Case Series.

Shalhout SZ, Kaufman HL, Sullivan RJ, et al.

Journal of immunotherapy (Hagerstown, Md. : 1997) 2021; (44(6)):234-238 doi:10.1097/CJI.0000000000000376.

Wound Care for Venous Ulceration.

Schroeppel DeBacker SE, Bulman JC, Weinstein JL

Seminars in interventional radiology 2021; (38(2)):194-201 doi:10.1055/s-0041-1727161.

What's new in the 2020 update of the CEAP classification system of chronic venous disease?

Musil D

Vnitrni lekarstvi 2021; (67(3)):143-148.

A systematic review of management of superficial venous reflux in the setting of deep venous obstruction.

Benfor B, Peden EK

Journal of vascular surgery. Venous and lymphatic disorders 2022; (10(4)):945-954.e2 doi:10.1016/j.jvsv.2021.12.087.

Effects of inspiratory muscle training versus calf muscle training on quality of life, pain, venous function and activity in patients with chronic venous insufficiency.

Aydin G, Yeldan I, Akgul A, Ipek G

Journal of vascular surgery. Venous and lymphatic disorders 2022; (10(5)):1137-1146 doi:10.1016/j.jvsv.2022.04.012.

Specific management of lipodermatosclerosis (sclerotic hypodermitis) in acute and chronic phase.

Klejtman T, Lazareth I, Yannoutsos A, Priollet P

Journal de medecine vasculaire 2022; (47(4)):186-190 doi:10.1016/j.jdmv.2022.10.006.

Post-treatment course of acute lipodermatosclerosis.

Suehiro K, Morikage N, Harada T, et al.

Phlebology 2023; (38(2)):73-79 doi:10.1177/02683555221147473.

Heparin-Induced Thrombocytopenia at the Emergency Department Due to Intermittent Heparin Flush in a Patient Undergoing Stem Cell Transplant.

Thein KZ, Elsaim SA, Ma MQ, et al.

Cureus 2022; (14(11)):e31798 doi:10.7759/cureus.31798.

Stasis Dermatitis: An Overview of Its Clinical Presentation, Pathogenesis, and Management.

Yosipovitch G, Nedorost ST, Silverberg JI, et al.

American journal of clinical dermatology 2023; (24(2)):275-286 doi:10.1007/s40257-022-00753-5.

Consistent application of compression: An under-considered variable in the prevention of venous leg ulcers.

Shawa HJ, Dahle SE, Isseroff RR

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2023; (31(3)):393-400 doi:10.1111/wrr.13078.

Chronic Venous Insufficiency and Lymphedema With Papillomatosis Cutis Lymphostatica, Hyperkeratosis, and Skin Ulcers: A Case Report.

Senanayake J, Chaudhari S, Haji Rahman R, et al.

Cureus 2023; (15(2)):e35326 doi:10.7759/cureus.35326.

Effect of passive ankle movement in the sitting position on the symptoms of chronic venous insufficiency with long-term observation.

Wnuk BR, Ziaja D, Buczek M, et al.

Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024; (33(2)):135-141 doi:10.17219/acem/166046.

A Systematic Review and Meta-Analysis of Randomised Controlled Trials Comparing Thermal Versus Non-Thermal Endovenous Ablation in Superficial Venous Incompetence.

Shahzad N, Elsherif M, Obaidat I, Brar R

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2023; (66(5)):687-695 doi:10.1016/j.ejvs.2023.06.002.

Physical exercise for the treatment of non-ulcerated chronic venous insufficiency.

Araujo DN, Ribeiro CT, Maciel AC, et al.

The Cochrane database of systematic reviews 2023; (6()):CD010637 doi:10.1002/14651858.CD010637.pub3.

Xioglican Cream in Italian Patients with Chronic Venous Disease: A Post-Marketing Study Investigating Effects on Clinical and Cutaneous Signs and Symptoms.

Muratori IM, Contorno F, Amato C

Advances in therapy 2023; (40(11)):4972-4986 doi:10.1007/s12325-023-02665-0.

Stasis Dermatitis: The Burden of Disease, Diagnosis, and Treatment.

Yosipovitch G, Jackson JM, Nedorost ST, et al.

Dermatitis : contact, atopic, occupational, drug 2024; (35(4)):337-344 doi:10.1089/derm.2022.0076.

Chronic venous insufficiency and venous leg ulcers: Aetiology, on the pathophysiology-based treatment.

Krizanova O, Penesova A, Hokynkova A, et al.

International wound journal 2024; (21(2)):e14405 doi:10.1111/iwj.14405.

Fatal anabolic androgenic steroid overdose in an amateur bodybuilder: a clinical and autopsy report.

Shaha KK, Nagappan R, Badhe BA

Forensic science, medicine, and pathology 2024; (20(4)):1420-1424 doi:10.1007/s12024-023-00747-7.

Weight Loss Induced by Antiobesity Medications and All-Cause Mortality Among Patients With Knee or Hip Osteoarthritis.

Wei J, Hunter D, Lane NE, et al.

Arthritis & rheumatology (Hoboken, N.J.) 2024; (76(4)):577-586 doi:10.1002/art.42754.

The Differential Diagnosis of Leg Ulcers.

Dissemond J, Placke JM, Moelleken M, Kröger K

Deutsches Arzteblatt international 2024; (121(22)):733-739.

The impact of wearing compression hosiery and the use of assistive products for donning and doffing: A descriptive qualitative study into user experiences.

Hagedoren-Meuwissen E, Roentgen U, Zwakhalen S, et al.

PloS one 2024; (19(12)):e0316034 doi:10.1371/journal.pone.0316034.

Glycocalyx disruption, endothelial dysfunction and vascular remodeling as underlying mechanisms and treatment targets of chronic venous disease.

Diaz JA, Gianesini S, Khalil RA

International angiology : a journal of the International Union of Angiology 2024; (43(6)):563-590 doi:10.23736/S0392-9590.24.05339-2.

Lipodermatosclerosis: from pathophysiology to treatment.

Alsararatee HH

British journal of nursing (Mark Allen Publishing) 2025; (34(3)):134-139 doi:10.12968/bjon.2024.0448.

Stanozolol-induced Liver Injury: A Distinctive Cholestatic Clinical and Biochemical Phenotype at Presentation.

Nunes V, Schinoni MI, Bessone F, et al.

Journal of clinical and experimental hepatology 2025; (15(3)):102506 doi:10.1016/j.jceh.2025.102506.

Evaluation of clinical and ultrasonographic prognostic factors for detection of iliac venous obstructions in patients with advanced chronic venous insufficiency.

Stegun VCG, Metzger PB, Cavalcante AACM, et al.

Phlebology 2025; (40(8)):600-608 doi:10.1177/02683555251326040.

Acute Inflammatory Edema: A Frequently Overlooked Case of Pseudocellulitis.

Gunawan H, Atiyah D, Maharani RH, et al.

Clinical, cosmetic and investigational dermatology 2025; (18()):729-733 doi:10.2147/CCID.S500048.

Diagnosis of Venous Thromboembolism.

Canas A, Epstein J, Chen T, Dunn AS

The Medical clinics of North America 2025; (109(4)):787-801 doi:10.1016/j.mcna.2025.01.006.

1% polidocanol endovenous microfoam (VarithenaTM) for the treatment of chronic venous disease: A position statement from the American vein and lymphatic society.

Meissner MH, Di Iorio M, Davies A

Phlebology 2026; (41(2)):89-96 doi:10.1177/02683555251353150.

A reduced multicomponent bandage compression system in the management of venous leg ulcers: a clinical evaluation.

Tickle J, Robinson H, Stubbings W, et al.

Journal of wound care 2025; (34(11)):922-931 doi:10.12968/jowc.2025.0457.

What is the recommended compression pressure for different clinical indications?

Mosti G, Benigni JP, Caggiati A

Phlebology 2026; (41(7)):600-610 doi:10.1177/02683555251410002.

[Postthrombotic syndrome: an update].

Reich-Schupke S

Dermatologie (Heidelberg, Germany) 2026; (77(5)):315-319 doi:10.1007/s00105-026-05662-w.

Angiosarcoma Presenting as a Chronic Non-Healing Lower Extremity Ulcer in Lymphoedema: A Challenge.

Koch M, Hani L, Friedman E, Ross FL

International wound journal 2026; (23(9)):e71002 doi:10.1111/iwj.71002.