Research & Literature

Multiple hepatic sclerosing hemangioma mimicking metastatic liver tumor successfully treated by laparoscopic surgery: Report of a case.

Wakasugi M, Ueshima S, Tei M, et al.

International journal of surgery case reports 2015; (8C()):137-40.

Tumor size is not a criterion for resection during the management of giant hemangioma of the liver.

Dong J, Zhang M, Chen JQ, et al.

European journal of gastroenterology & hepatology 2015; (27(6)):686-91 doi:10.1097/MEG.0000000000000344.

New recognition of the natural history and growth pattern of hepatic hemangioma in adults.

Jing L, Liang H, Caifeng L, et al.

Hepatology research : the official journal of the Japan Society of Hepatology 2016; (46(8)):727-33 doi:10.1111/hepr.12610.

Prevalence and clinical outcome of hepatic haemangioma with specific reference to the risk of rupture: A large retrospective cross-sectional study.

Mocchegiani F, Vincenzi P, Coletta M, et al.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2016; (48(3)):309-14.

Spontaneous rupture of hepatic hemangioma: a case report and literature review.

Zhao W, Guo X, Dong J

International journal of clinical and experimental pathology 2015; (8(10)):13426-8.

Giant cavernous liver hemangiomas: is it the time to change the size categories?

Di Carlo I, Koshy R, Al Mudares S, et al.

Hepatobiliary & pancreatic diseases international : HBPD INT 2016; (15(1)):21-9 doi:10.1016/s1499-3872(15)60035-2.

Obstructive jaundice caused by a giant liver hemangioma with Kasabach-Merritt syndrome: a case report.

Yano T, Kobayashi T, Kuroda S, et al.

Surgical case reports 2015; (1(1)):93 doi:10.1186/s40792-015-0095-4.

Clinical case report: Sclerosing hemangioma of the liver, a rare but great mimicker.

Behbahani S, Hoffmann JC, Stonebridge R, Mahboob S

Radiology case reports 2016; (11(2)):58-61 doi:10.1016/j.radcr.2016.02.015.

Characteristics and operative treatment of extremely giant liver hemangioma >20 cm.

Liu X, Yang Z, Tan H, et al.

Surgery 2017; (161(6)):1514-1524 doi:10.1016/j.surg.2016.12.015.

Proposal of size-based surgical indication criteria for liver hemangioma based on a nationwide survey in Japan.

Sakamoto Y, Kokudo N, Watadani T, et al.

Journal of hepato-biliary-pancreatic sciences 2017; (24(7)):417-425 doi:10.1002/jhbp.464.

[Liver hemangiomas - when is invasive treatment indicated?]

Třeška V, Skalický T, Liška V, et al.

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti 2017; (96(4)):151-155.

Enucleation versus Anatomic Resection for Giant Hepatic Hemangioma: A Meta-Analysis.

Liu Y, Wei X, Wang K, et al.

Gastrointestinal tumors 2017; (3(3-4)):153-162 doi:10.1159/000455846.

Giant liver hemangioma with adult Kasabach-Merritt syndrome: Case report and literature review.

Liu X, Yang Z, Tan H, et al.

Medicine 2017; (96(31)):e7688 doi:10.1097/MD.0000000000007688.

Long-term result of transcatheter arterial embolization for liver hemangioma.

Liu X, Yang Z, Tan H, et al.

Medicine 2017; (96(49)):e9029 doi:10.1097/MD.0000000000009029.

Hepatic sclerosed hemangioma with special attention to diffusion-weighted magnetic resonance imaging.

Miyata T, Beppu T, Kuramoto K, et al.

Surgical case reports 2018; (4(1)):3 doi:10.1186/s40792-017-0414-z.

Atypical hemangioma mimicking mixed hepatocellular cholangiocarcinoma: Case report.

Lin S, Zhang L, Li M, et al.

Medicine 2017; (96(50)):e9192 doi:10.1097/MD.0000000000009192.

Cavernous liver hemangioma complicated with spontaneous intratumoral hemorrhage: a case report and literature review.

Dima-Cozma LC, Bitere OR, Pantazescu AN, et al.

Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2018; (59(2)):557-561.

Preoperative diagnosis of the sclerosed hemangioma of the liver using multimodality imaging findings: A case report.

Ozaki K, Yoshikawa J, Yamamoto T, et al.

Radiology case reports 2018; (13(5)):1025-1029 doi:10.1016/j.radcr.2018.04.007.

Isolated hepatic hemangiomatosis in 2 septuagenarians.

Liu MC, Little EC

Radiology case reports 2018; (13(6)):1097-1103 doi:10.1016/j.radcr.2018.08.018.

Guidance Document for Hepatic Hemangioma (Infantile and Congenital) Evaluation and Monitoring.

Iacobas I, Phung TL, Adams DM, et al.

The Journal of pediatrics 2018; (203()):294-300.e2 doi:10.1016/j.jpeds.2018.08.012.

[The epidemiological and clinical characteristics of liver hemangioma in health adults].

Huang J, Liu XL, Tan HD, et al.

Zhonghua yi xue za zhi 2018; (98(36)):2925-2928 doi:10.3760/cma.j.issn.0376-2491.2018.36.010.

Hepatic Sclerosing Hemangioma Simulating Gallbladder Carcinoma: A Rare Case.

Navale P, Habib M, Stueck A, Fiel MI

Journal of clinical and experimental hepatology 2018; (8(4)):474-477 doi:10.1016/j.jceh.2018.07.003.

Transarterial (Chemo-)Embolization and Lipiodolization for Hepatic Haemangioma.

Furumaya A, van Rosmalen BV, Takkenberg RB, et al.

Cardiovascular and interventional radiology 2019; (42(6)):800-811 doi:10.1007/s00270-019-02169-x.

Benign liver tumors

Blaise L, Sutter O, Ziol M, Nault JC

La Revue du praticien 2018; (68(10)):1119-1124.

Invasive management of symptomatic hepatic hemangioma.

Dong W, Qiu B, Xu H, He L

European journal of gastroenterology & hepatology 2019; (31(9)):1079-1084 doi:10.1097/MEG.0000000000001413.

Spontaneous hepatic haemangioma rupture and hemoperitoneum: a double problem with a single stage interventional radiology solution.

Rossi UG, Camisassi N, Pinna F, Rollandi GA

Clinical and experimental emergency medicine 2019; (6(2)):169-172 doi:10.15441/ceem.18.008.

An Effective Method for Controlling Bleeding in a Ruptured Hepatic Hemangioma: A Case Report.

Talebpour M, Zabihi-Mahmoudabadi H, Payandemehr P, et al.

Advanced journal of emergency medicine 2019; (3(1)):e10 doi:10.22114/AJEM.v0i0.114.

Hepatic Hemangioma in a Cluster of Iranian Population.

Kamyab AA, Rezaei-Kalantari K

Journal of medical ultrasound 2019; (27(2)):97-100 doi:10.4103/JMU.JMU_98_18.

Hepatic hemangioma: What internists need to know.

Leon M, Chavez L, Surani S

World journal of gastroenterology 2020; (26(1)):11-20 doi:10.3748/wjg.v26.i1.11.

Percutaneous ultrasound-guided 'three-step' radiofrequency ablation for giant hepatic hemangioma (5-15 cm): a safe and effective new technique.

Qu C, Liu H, Li XQ, et al.

International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2020; (37(1)):212-219 doi:10.1080/02656736.2020.1732484.

Hepatic hemangiomas: the various imaging avatars and its mimickers.

Mathew RP, Sam M, Raubenheimer M, et al.

La Radiologia medica 2020; (125(9)):801-815 doi:10.1007/s11547-020-01185-z.

Failed angioembolization of a ruptured liver hemangioma complicated by iatrogenic injury of subclavian vein during catheter insertion.

Kang WS, Jo YG, Park YC

Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES 2020; (26(4)):635-638 doi:10.14744/tjtes.2019.04343.

Giant Liver Hemangiomas: A Plea for Early Surgical Referral and Resection.

Chang A, Ruch B, Khan A, et al.

Case reports in surgery 2020; (2020()):5923787 doi:10.1155/2020/5923787.

Evaluation of Primary Liver Cancers Using Hepatocyte-Specific Contrast-Enhanced MRI: Pitfalls and Potential Tips.

Kim JH, Yoon JH, Joo I, Lee JM

Journal of magnetic resonance imaging : JMRI 2021; (53(3)):655-675 doi:10.1002/jmri.27213.

A hepatic sclerosed hemangioma with drastic changes in contrast-enhanced ultrasonography.

Akahoshi S, Yamamura K, Sato N, et al.

Clinical journal of gastroenterology 2020; (13(6)):1252-1257 doi:10.1007/s12328-020-01194-5.

Guidelines and Good Clinical Practice Recommendations for Contrast Enhanced Ultrasound (CEUS) in the Liver - Update 2020 - WFUMB in Cooperation with EFSUMB, AFSUMB, AIUM, and FLAUS.

Dietrich CF, Nolsøe CP, Barr RG, et al.

Ultraschall in der Medizin (Stuttgart, Germany : 1980) 2020; (41(5)):562-585 doi:10.1055/a-1177-0530.

A rare case of cavernous hemangioma accompanied with diffuse hepatic hemangiomatosis.

Ota T, Kamiyama T, Kato T, et al.

Surgical case reports 2020; (6(1)):251 doi:10.1186/s40792-020-01023-4.

Benign Liver Tumors.

Oldhafer KJ, Habbel V, Horling K, et al.

Visceral medicine 2020; (36(4)):292-303 doi:10.1159/000509145.

Giant intrahepatic venous malformation with localized intravascular coagulopathy. Follow-up and treatment during pregnancy.

Serrano F, Bisdorff-Bresson A, Sroussi J, et al.

Journal de medecine vasculaire 2020; (45(6)):309-315 doi:10.1016/j.jdmv.2020.10.121.

Gadoxetic acid-enhanced MRI for differentiating hepatic sclerosing hemangioma from malignant tumor.

Kim YY, Kang TW, Cha DI, et al.

European journal of radiology 2021; (135()):109474 doi:10.1016/j.ejrad.2020.109474.

Two hepatic cavernous hemangiomas mimicking colorectal liver metastasis: A rare case report.

Alsofyani TM, Aldossary MY, AlQahtani FF, et al.

International journal of surgery case reports 2021; (81()):105817 doi:10.1016/j.ijscr.2021.105817.

Hepatic sclerosed hemangioma and sclerosing cavernous hemangioma: a radiological study.

Jia C, Liu G, Wang X, et al.

Japanese journal of radiology 2021; (39(11)):1059-1068 doi:10.1007/s11604-021-01139-z.

Complications of Radiofrequency Ablation for Hepatic Hemangioma: A Multicenter Retrospective Analysis on 291 Cases.

Wu S, Gao R, Yin T, et al.

Frontiers in oncology 2021; (11()):706619 doi:10.3389/fonc.2021.706619.

Real-world data on the clinicopathological traits and outcomes of hospitalized liver hemangioma patients: a multicenter study.

Tang T, Wang X, Mao Y, et al.

Annals of translational medicine 2021; (9(13)):1067 doi:10.21037/atm-20-4684.

Oral Progestins in Hormonal Contraception: Importance and Future Perspectives of a New Progestin Only-Pill Containing 4 mg Drospirenone.

Römer T, Bitzer J, Egarter C, et al.

Geburtshilfe und Frauenheilkunde 2021; (81(9)):1021-1030 doi:10.1055/a-1471-4408.

One stop shop approach for the diagnosis of liver hemangioma.

Sandulescu LD, Urhut CM, Sandulescu SM, et al.

World journal of hepatology 2021; (13(12)):1892-1908 doi:10.4254/wjh.v13.i12.1892.

Management of hepatic haemangioma in pregnancy.

Casabianca AS, Hernandez Caballero AI, Thornburg LL, Carpizo D

BMJ case reports 2022; (15(6)) doi:10.1136/bcr-2022-248932.

A Comprehensive Review of Hepatic Hemangioma Management.

Aziz H, Brown ZJ, Baghdadi A, et al.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2022; (26(9)):1998-2007 doi:10.1007/s11605-022-05382-1.

Ruptured Hepatic Hemangioma in the Third Trimester of Pregnancy: A Rare Case Report.

Ward H, Hosseini O, Hashimoto Y, Soliman B

Cureus 2022; (14(5)):e25397 doi:10.7759/cureus.25397.

The surgical outcomes and risk factors of giant hepatic haemangiomas: a single centre experience.

Dong Z, Fang K, Sui C, et al.

BMC surgery 2022; (22(1)):278 doi:10.1186/s12893-022-01721-w.

Prevalence and Characteristics of Hepatic Hemangioma Associated with Coagulopathy and Its Predictive Risk Factors.

Maruyama S, Matono T, Koda M

Journal of clinical medicine 2022; (11(15)) doi:10.3390/jcm11154347.

Case Report: Spontaneous Rupture of Hepatic Hemangioma.

Pan B, Lyu SC, He Q

Frontiers in medicine 2022; (9()):918748 doi:10.3389/fmed.2022.918748.

Comparison of Hepatectomy and Hemangiomas Stripping on Patients with Giant Hepatic Hemangiomas.

Yang Z, Zhang C, Li Z, et al.

Contrast media & molecular imaging 2022; (2022()):1350826 doi:10.1155/2022/1350826.

Transarterial embolization for rare spontaneous subacute intratumoral hemorrhage of hepatic hemangioma: a case report and literature review.

Jia K, Yin W, Wang F, et al.

Translational cancer research 2022; (11(10)):3919-3926 doi:10.21037/tcr-22-837.

Feasibility of laparoscopic enucleation for hemangioma in special hepatic segments.

Li H, Duan X, Wu Z, Qin Y

Frontiers in surgery 2022; (9()):1111307 doi:10.3389/fsurg.2022.1111307.

Laparoscopic Hepatectomy for Giant Hepatic Hemangioma Using the Involved Intrahepatic Anatomic Markers Approach.

Du X, Zheng K, Jiang L

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2023; (27(6)):1290-1291 doi:10.1007/s11605-023-05623-x.

Pediatric hepatic vascular tumors: clinicopathologic characteristics of 33 cases and proposed updates to current classification schemes.

Berklite L, Malik F, Ranganathan S, Gupta A

Human pathology 2023; (141()):78-89 doi:10.1016/j.humpath.2023.05.013.

Natural History of Hepatic Hemangiomas Larger Than 10 cm: Imaging Findings and Clinical Course of 22 Cases.

Onishi Y, Ohno T, Shimizu H, et al.

Cureus 2023; (15(12)):e50563 doi:10.7759/cureus.50563.

Giant hepatic hemangioma in a patient with cirrhosis: challenging to manage.

Cunha-Silva M, Veiga CT, da Costa LBE, et al.

Autopsy & case reports 2024; (14()):e2024485 doi:10.4322/acr.2024.485.

Case report: A rare immune-related adverse effect: hepatic cavernous hemangioma induced by camrelizumab.

Zhang C, Wang G, Liu N, et al.

Frontiers in immunology 2024; (15()):1387465 doi:10.3389/fimmu.2024.1387465.

Giant pedunculated hepatic hemangioma accompanied by a 10-year history of taking oral contraceptive: A case report and literature review.

Samidoust P, Moayerifar M, Mohammadian M, et al.

Clinical case reports 2024; (12(6)):e8995 doi:10.1002/ccr3.8995.

Spontaneous Atraumatic Rupture of a Liver Hemangioma as a Rare Cause of Syncope.

Sidler F, Turcan V, Storni F, et al.

Case reports in hepatology 2024; (2024()):7921410 doi:10.1155/2024/7921410.

U.S. Medical Eligibility Criteria for Contraceptive Use, 2024.

Nguyen AT, Curtis KM, Tepper NK, et al.

MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports 2024; (73(4)):1-126 doi:10.15585/mmwr.rr7304a1.

Can Dynamic Contrast-Enhanced MRI Be Used to Differentiate Hepatic Hemangioma from Other Lesions in Early Infancy?

Halevy D, Sayed BA, Shaikh F, et al.

The Indian journal of radiology & imaging 2024; (34(4)):612-619 doi:10.1055/s-0044-1785208.

A Rare Encounter: Hepatomegaly Unmasked as Multiple Giant Hepatic Hemangiomas.

Gopalan V, Tote D, Zade AA, et al.

Cureus 2024; (16(9)):e68814 doi:10.7759/cureus.68814.

Active Liver Bleed Caught During FAST Exam from Spontaneous Hemangioma Rupture: A Case Report.

Rodriguez R, Aviles N

Clinical practice and cases in emergency medicine 2025; (9(1)):98-101 doi:10.5811/cpcem.21315.

Primary hepatic angiosarcoma mistaken for a giant hemangioma.

Qian XJ, Girgis S, Wilson MP, Low G

Intractable & rare diseases research 2025; (14(1)):85-87 doi:10.5582/irdr.2024.01045.

Diagnosis and Management of Benign Liver Tumors.

Ha Y

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 2025; (85(3)):314-318 doi:10.4166/kjg.2025.046.

Simultaneous degenerative changes in 2 hepatic cavernous hemangiomas observed over 23 years of follow-up: A case report and review of the literature.

Kawaguchi T, Arinaga-Hino T, Tanoue S, et al.

Radiology case reports 2026; (21(1)):343-348 doi:10.1016/j.radcr.2025.09.089.

A Study on the Characteristics of Sonazoid Contrast-Enhanced Ultrasound in the Transitional Phase for Common Focal Liver Lesions and Its Value in Differential Diagnosis.

Luo Y, Wen D, Zhang J, et al.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 2026; (45(6)):1235-1245 doi:10.1002/jum.70162.

Cardiovascular Safety of Hormonal Contraception: Method-Specific Risks and Clinical Implications.

Waluszewska I, Borowiec A, Paciorek A, et al.

Medical sciences (Basel, Switzerland) 2026; (14(2)) doi:10.3390/medsci14020201.

Open Parenchyma-Preserving Enucleation of Giant Hepatic Hemangiomas: A Systematic Cavitron Ultrasonic Surgical Aspirator (CUSA)-Guided Pringle-Free Technique.

Khalifeh M, Khalifeh J, Jradi A, et al.

Cureus 2026; (18(4)):e106383 doi:10.7759/cureus.106383.

Spontaneous regression of a giant hepatic hemangioma on serial MRI: A case report with 3-year follow-up.

Qirinxhi D, Çela D, Saraci B, Bilaj F

Radiology case reports 2026; (21(10)):4869-4873 doi:10.1016/j.radcr.2026.06.162.

Use of the Term "Atypical Hepatic Hemangioma" in Radiology Reports: An Analysis of Diagnostic Precision.

Tamir S, Krutik T, Kedem Mashraki R, et al.

Journal of clinical medicine 2026; (15(15)) doi:10.3390/jcm15155923.

Consumptive coagulopathy and fatal outcome in hepatic hemangioma: a rare adult case of Kasabach-Merritt syndrome.

Derkaoui A, Deflaoui T, Aissi I, et al.

International journal of surgery case reports 2026; (138(9)):3743-3746 doi:10.1097/RC9.0000000000000837.