Research & Literature

In Vivo Confocal Microscopy 1 Year after Autologous Cultured Limbal Stem Cell Grafts.

Pedrotti E, Passilongo M, Fasolo A, et al.

Ophthalmology 2015; (122(8)):1660-8.

Epithelial Thinning in Limbal Stem Cell Deficiency.

Chan EH, Chen L, Yu F, Deng SX

American journal of ophthalmology 2015; (160(4)):669-77.e4.

Ocular surface reconstruction using stem cell and tissue engineering.

Nakamura T, Inatomi T, Sotozono C, et al.

Progress in retinal and eye research 2016; (51()):187-207.

[Long-term results of autologous transplantation of limbal epithelium cultivated ex vivo for limbal stem cell deficiency].

Scholz SL, Thomasen H, Hestermann K, et al.

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 2016; (113(4)):321-9 doi:10.1007/s00347-015-0110-y.

Limbal Stem Cell Transplantation for Soft Contact Lens Wear-Related Limbal Stem Cell Deficiency.

Shen C, Chan CC, Holland EJ

American journal of ophthalmology 2015; (160(6)):1142-1149.e1.

Stability of limbal stem cell deficiency after mechanical and thermal injuries in mice.

Afsharkhamseh N, Movahedan A, Gidfar S, et al.

Experimental eye research 2016; (145()):88-92 doi:10.1016/j.exer.2015.11.012.

Assessment of PAX6 alleles in 66 families with aniridia.

Bobilev AM, McDougal ME, Taylor WL, et al.

Clinical genetics 2016; (89(6)):669-77 doi:10.1111/cge.12708.

Limbal Stem Cell Deficiency: Current Treatment Options and Emerging Therapies.

Haagdorens M, Van Acker SI, Van Gerwen V, et al.

Stem cells international 2016; (2016()):9798374 doi:10.1155/2016/9798374.

Limbal stem cell transplantation: current perspectives.

Atallah MR, Palioura S, Perez VL, Amescua G

Clinical ophthalmology (Auckland, N.Z.) 2016; (10()):593-602 doi:10.2147/OPTH.S83676.

Characterization of the corneal surface in limbal stem cell deficiency and after transplantation of cultured allogeneic limbal epithelial cells.

Chen P, Zhou Q, Wang J, et al.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2016; (254(9)):1765-77 doi:10.1007/s00417-016-3410-2.

Existence of Normal Limbal Epithelium in Eyes With Clinical Signs of Total Limbal Stem Cell Deficiency.

Chan E, Le Q, Codriansky A, et al.

Cornea 2016; (35(11)):1483-1487 doi:10.1097/ICO.0000000000000914.

In vivo confocal microscopy of the sclerocorneal limbus after limbal stem cell transplantation: Looking for limbal architecture modifications and cytological phenotype correlations.

Mastropasqua L, Calienno R, Lanzini M, et al.

Molecular vision 2016; (22()):748-60.

Simple Limbal Epithelial Transplantation in Acid Injury and Severe Dry Eye.

Arya SK, Bhatti A, Raj A, Bamotra RK

Journal of clinical and diagnostic research : JCDR 2016; (10(6)):ND06-7 doi:10.7860/JCDR/2016/19306.7997.

Correlation between the existence of the palisades of Vogt and limbal epithelial thickness in limbal stem cell deficiency.

Le Q, Yang Y, Deng SX, Xu J

Clinical & experimental ophthalmology 2017; (45(3)):224-231 doi:10.1111/ceo.12832.

Long-term results of allogenic penetrating limbo-keratoplasty: 20 years of experience.

Lang SJ, Böhringer D, Geerling G, Reinhard T

Eye (London, England) 2017; (31(3)):372-378 doi:10.1038/eye.2016.217.

[Limbal epithelial stem cell transplantation : Current state and perspectives].

Meller D, Thomasen H

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 2017; (114(4)):298-306 doi:10.1007/s00347-017-0462-6.

Conjunctival-limbal autograft.

Daya SM

Current opinion in ophthalmology 2017; (28(4)):370-376 doi:10.1097/ICU.0000000000000385.

Safety of Cultivated Limbal Epithelial Stem Cell Transplantation for Human Corneal Regeneration.

Behaegel J, Ní Dhubhghaill S, Koppen C, Zakaria N

Stem cells international 2017; (2017()):6978253 doi:10.1155/2017/6978253.

Outcomes of Keratoplasty After Ocular Surface Stem Cell Transplantation.

Sepsakos L, Cheung AY, Holland EJ

Cornea 2017; (36(9)):1025-1030 doi:10.1097/ICO.0000000000001267.

Limbal Stem Cell Transplantation and Complications.

Yin J, Jurkunas U

Seminars in ophthalmology 2018; (33(1)):134-141 doi:10.1080/08820538.2017.1353834.

Results of simple limbal epithelial transplantation in unilateral ocular surface burn.

Gupta N, Joshi J, Farooqui JH, Mathur U

Indian journal of ophthalmology 2018; (66(1)):45-52 doi:10.4103/ijo.IJO_602_17.

Simple limbal epithelial transplantation (SLET) in failed cultivated limbal epithelial transplantation (CLET) for unilateral chronic ocular burns.

Basu S, Mohan S, Bhalekar S, et al.

The British journal of ophthalmology 2018; (102(12)):1640-1645 doi:10.1136/bjophthalmol-2017-311506.

Simple limbal epithelial transplantation: a review on current approach and future directions.

Borroni D, Wowra B, Romano V, et al.

Survey of ophthalmology 2018; (63(6)):869-874 doi:10.1016/j.survophthal.2018.05.003.

Drug-Drug Interaction Between Isavuconazole and Tacrolimus: Is Empiric Dose Adjustment Necessary?

Kufel WD, Armistead PM, Daniels LM, et al.

Journal of pharmacy practice 2020; (33(2)):226-230 doi:10.1177/0897190018790688.

Systemic immunosuppression in limbal stem cell transplantation: best practices and future challenges.

Ballios BG, Weisbrod M, Chan CC, et al.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 2018; (53(4)):314-323 doi:10.1016/j.jcjo.2017.10.040.

Functional reassessment of PAX6 single nucleotide variants by in vitro splicing assay.

Filatova AY, Vasilyeva TA, Marakhonov AV, et al.

European journal of human genetics : EJHG 2019; (27(3)):488-493 doi:10.1038/s41431-018-0288-y.

In vivo confocal microscopy and optical coherence tomography as innovative tools for the diagnosis of limbal stem cell deficiency.

Banayan N, Georgeon C, Grieve K, et al.

Journal francais d'ophtalmologie 2018; (41(9)):e395-e406 doi:10.1016/j.jfo.2018.09.003.

[In vivo confocal microscopy and optical coherence tomography as innovative tools for the diagnosis of limbal stem cell deficiency (French translation of the article)].

Banayan N, Georgeon C, Grieve K, et al.

Journal francais d'ophtalmologie 2018; (41(10)):968-980 doi:10.1016/j.jfo.2018.07.004.

Ocular Surface Reconstruction Using Circumferentially-trephined Autologous Oral Mucosal Graft Transplantation in Limbal Stem Cell Deficiency.

Choe HR, Yoon CH, Kim MK

Korean journal of ophthalmology : KJO 2019; (33(1)):16-25 doi:10.3341/kjo.2018.0111.

Vision Rehabilitation with a Native Pintucci-type Keratoprosthesis.

Rahmani S, Bagheri A, Karimian F, et al.

Journal of ophthalmic & vision research 2019; (14(1)):101-104 doi:10.4103/jovr.jovr_52_17.

Comparison of the efficacy of different cell sources for transplantation in total limbal stem cell deficiency.

Wang J, Qi X, Dong Y, et al.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2019; (257(6)):1253-1263 doi:10.1007/s00417-019-04316-z.

[Panorama of limbal alterations (French translation of the article)].

Gueudry J, Majo F, Delcampe A, Muraine M

Journal francais d'ophtalmologie 2019; (42(5)):517-528 doi:10.1016/j.jfo.2018.08.016.

Autologous limbal stem cell transplantation: a systematic review of clinical outcomes with different surgical techniques.

Shanbhag SS, Nikpoor N, Rao Donthineni P, et al.

The British journal of ophthalmology 2020; (104(2)):247-253 doi:10.1136/bjophthalmol-2019-314081.

Evaluating Dry Eye and Meibomian Gland Dysfunction With Meibography in Patients With Stevens-Johnson Syndrome.

Lekhanont K, Jongkhajornpong P, Sontichai V, et al.

Cornea 2019; (38(12)):1489-1494 doi:10.1097/ICO.0000000000002025.

Commentary: SLET - A paradigm shift in limbal transplantation.

Vazirani J

Indian journal of ophthalmology 2019; (67(8)):1277-1278 doi:10.4103/ijo.IJO_610_19.

Tacrolimus: 20 years of use in adult kidney transplantation. What we should know about its nephrotoxicity.

Bentata Y

Artificial organs 2020; (44(2)):140-152 doi:10.1111/aor.13551.

Long-Term Results of Cultured Limbal Stem Cell Versus Limbal Tissue Transplantation in Stage III Limbal Deficiency.

Borderie VM, Ghoubay D, Georgeon C, et al.

Stem cells translational medicine 2019; (8(12)):1230-1241 doi:10.1002/sctm.19-0021.

Simple oral mucosal epithelial transplantation in a rabbit model.

Inamochi A, Tomioka A, Kitamoto K, et al.

Scientific reports 2019; (9(1)):18088 doi:10.1038/s41598-019-54571-7.

Anterior Segment Optical Coherence Tomography in the Early Management of Microbial Keratitis: A Cross-Sectional Study.

Oliveira MA, Rosa A, Soares M, et al.

Acta medica portuguesa 2020; (33(5)):318-325 doi:10.20344/amp.12663.

Limbal Stem Cell Deficiency After Glaucoma Surgery.

Sun Y, Yung M, Huang L, et al.

Cornea 2020; (39(5)):566-572 doi:10.1097/ICO.0000000000002249.

The utility of anterior segment optical coherence tomography angiography for the assessment of limbal stem cell deficiency.

Binotti WW, Nosé RM, Koseoglu ND, et al.

The ocular surface 2021; (19()):94-103 doi:10.1016/j.jtos.2020.04.007.

Limbal Stem Cell Dysfunction in Ichthyosis Follicularis, Alopecia, and Photophobia Syndrome.

Basilious A, Fung SSM, Ali A

Cornea 2020; (39(10)):1321-1324 doi:10.1097/ICO.0000000000002393.

Clinical Outcomes of Allogeneic Ocular Surface Stem Cell Transplantation in Pediatric Patients.

Cheung AY, Sarnicola E, Eslani M, et al.

Cornea 2021; (40(1)):54-60 doi:10.1097/ICO.0000000000002379.

Multi-parametric evaluation of autologous cultivated Limbal epithelial cell transplantation outcomes of Limbal stem cell deficiency due to chemical burn.

Selver OB, Gurdal M, Yagci A, et al.

BMC ophthalmology 2020; (20(1)):325 doi:10.1186/s12886-020-01588-6.

Surgical Management of Limbal Stem Cell Deficiency.

Iyer G, Srinivasan B, Agarwal S, et al.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) 2020; (9(6)):512-523 doi:10.1097/APO.0000000000000326.

[Research progress on limbal stem cell transplantation].

Wang LY, Liang QF

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology 2020; (56(12)):956-960 doi:10.3760/cma.j.cn112142-20201022-00526.

Formulation and Stability of Ataluren Eye Drop Oily Solution for Aniridia.

Djayet C, Bremond-Gignac D, Touchard J, et al.

Pharmaceutics 2020; (13(1)) doi:10.3390/pharmaceutics13010007.

Allograft rejection after living-related simple limbal epithelial transplantation.

Vazirani J, Basu S, Sangwan VS

Indian journal of ophthalmology 2021; (69(2)):433-435 doi:10.4103/ijo.IJO_1952_20.

Ocular toxicity of mustard gas: A concise review.

Fuchs A, Giuliano EA, Sinha NR, Mohan RR

Toxicology letters 2021; (343()):21-27 doi:10.1016/j.toxlet.2021.02.007.

[Simple limbal epithelial transplantation (SLET) : A simple technique for the treatment of unilateral complete limbal stem cell deficiency. Video article].

Prinz J, Mehta JS, Walter P, Fuest M

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 2021; (118(4)):404-412 doi:10.1007/s00347-021-01346-z.

Economic, clinical and social impact of simple limbal epithelial transplantation for limbal stem cell deficiency.

Thokala P, Singh A, Singh VK, et al.

The British journal of ophthalmology 2022; (106(7)):923-928 doi:10.1136/bjophthalmol-2020-318642.

Bilateral Limbal Stem Cell Alterations in Patients With Unilateral Herpes Simplex Keratitis and Herpes Zoster Ophthalmicus as Shown by In Vivo Confocal Microscopy.

Liu X, Xu S, Wang Y, et al.

Investigative ophthalmology & visual science 2021; (62(6)):12 doi:10.1167/iovs.62.6.12.

Corneal Epithelial Stem Cells-Physiology, Pathophysiology and Therapeutic Options.

Ruan Y, Jiang S, Musayeva A, et al.

Cells 2021; (10(9)) doi:10.3390/cells10092302.

Ritanserin, a potent serotonin 2A receptor antagonist, represses MEK/ERK signalling pathway to restore PAX6 production and function in aniridia-like cellular model.

Oved K, Zennaro L, Dorot O, et al.

Biochemical and biophysical research communications 2021; (582()):100-104 doi:10.1016/j.bbrc.2021.10.036.

Labial mucosal epithelium grafting in an ex vivo human donor cornea model.

Gerasimov MY, Ostrovskiy DS, Shatskikh AV, et al.

Experimental eye research 2022; (216()):108931 doi:10.1016/j.exer.2022.108931.

Current and Emerging Therapies for Limbal Stem Cell Deficiency.

Elhusseiny AM, Soleimani M, Eleiwa TK, et al.

Stem cells translational medicine 2022; (11(3)):259-268 doi:10.1093/stcltm/szab028.

Influence of graft vascularization on graft survival following homologous limbo-keratoplasty.

Lang SJ, Werner N, Böhringer D, et al.

International ophthalmology 2022; (42(10)):3053-3059 doi:10.1007/s10792-022-02291-9.

Allogeneic simple limbal epithelial transplantation for bilateral limbal stem cell deficiency in chronic vernal keratoconjunctivitis: A case report.

Jain N, Kate A, Chaudhary S, Basu S

International journal of surgery case reports 2022; (94()):106968 doi:10.1016/j.ijscr.2022.106968.

Novel detection of stem cell niche within the stroma of limbus in the rabbit during postnatal development.

Abdellah N, Desoky SMME

Scientific reports 2022; (12(1)):13711 doi:10.1038/s41598-022-18090-2.

Tacrolimus Concentration Is Effectively Predicted Using Combined Clinical and Genetic Factors in the Perioperative Period of Kidney Transplantation and Associated with Acute Rejection.

Cheng F, Li Q, Cui Z, et al.

Journal of immunology research 2022; (2022()):3129389 doi:10.1155/2022/3129389.

Outcomes of keratolimbal allograft from ABO compatible donors for severe bilateral limbal stem cell deficiency.

Mimouni M, Cole E, Kim SJ, et al.

The ocular surface 2023; (27()):48-53 doi:10.1016/j.jtos.2022.11.002.

Mycophenolate-Induced Hepatotoxicity Precipitates Tacrolimus Nephrotoxicity in a Kidney Transplant Recipient: A Case Report.

Chen CC, Chang WC, Lin SH

Transplantation proceedings 2022; (54(10)):2739-2743 doi:10.1016/j.transproceed.2022.10.036.

Outcome of keratolimbal allograft transplantation with deep anterior lamellar keratoplasty for bilateral limbal stem cell deficiency.

Li Z, Yang K, Zhou Y, et al.

Frontiers in medicine 2022; (9()):986194 doi:10.3389/fmed.2022.986194.

En Bloc Keratolimbal Allograft and Central Penetrating Keratoplasty: A Novel Surgical Technique in Severe Limbal Stem Cell Deficiency.

Karimian F, Hassanpour K

Cornea 2023; (42(5)):656-661 doi:10.1097/ICO.0000000000003199.

Long-Term Clinical Outcomes of Keratolimbal Allograft Alone or in Combination With Keratoplasty in Chronic and Delayed-Onset Mustard Gas Keratopathy.

Karimian F, Jafarinasab MR, Feizi S, et al.

Cornea 2023; (42(5)):536-543 doi:10.1097/ICO.0000000000003066.

Corneal squamous neoplasia: masquerades and management outcomes at a rural eyecare centre.

Agarwal A, Kaliki S, Murthy SI

BMJ case reports 2023; (16(5)) doi:10.1136/bcr-2022-254365.

Topical Tacrolimus Compared With Oral Tacrolimus for Postoperative Immunosuppression in Primary Keratolimbal Allograft.

Tran TM, Azher TN, Miller CJ, Hou JH

Cornea 2024; (43(3)):333-342 doi:10.1097/ICO.0000000000003316.

Case Report: Simultaneous penetrating keratoplasty with autologous simple limbal epithelial transplantation as an alternative to keratoprosthesis.

Sharma S, Singh S, Shanbhag SS

F1000Research 2023; (12()):488 doi:10.12688/f1000research.133637.3.

Spice-drug interactions: a case report on the use of turmeric, curry and ginger in a renal transplant patient on tacrolimus.

Boissiere C, Francois E, Vabret E, et al.

European journal of hospital pharmacy : science and practice 2023; (31(1)):68-69 doi:10.1136/ejhpharm-2023-003871.

A novel case of limbal stem cell deficiency in a patient with acrodermatitis enteropathica.

Sundareswaran G, Arora N, Sankarasubramaniam A

Oman journal of ophthalmology 2023; (16(2)):326-328 doi:10.4103/ojo.ojo_46_22.

Severity Classification of Limbal Stem Cell Failure Due to Steven Johnson Syndrome in the Light of the Classification Consensus of Limbal Stem Cell Deficiency.

Akgun Z, Palamar M, Egrilmez S, et al.

Eye & contact lens 2024; (50(4)):159-162 doi:10.1097/ICL.0000000000001073.

Limbal stem cell deficiency: Demography, aetiology, and clinical presentation in Eastern India.

Singh VK, Kumari N, Kusumesh R, Sinha BP

Journal of family medicine and primary care 2024; (13(1)):48-53 doi:10.4103/jfmpc.jfmpc_475_23.

Co-existence of Neurotrophic Keratopathy in Eyes With Limbal Stem Cell Deficiency.

Niruthisard D, Bonnet C, Fung SSM, et al.

American journal of ophthalmology 2024; (267()):249-256 doi:10.1016/j.ajo.2024.06.022.

Midterm results after allogeneic simple limbal epithelial transplantation from deceased-donor eyes in patients with persistent corneal epithelial defects due to limbal stem cell deficiency.

Riedl JC, Wasielica-Poslednik J, Giers BC, et al.

Acta ophthalmologica 2025; (103(2)):e125-e135 doi:10.1111/aos.16760.

Evaluation of Medically Reversible Limbal Stem Cell Deficiency.

Korkmaz İ, Eratılgan NF, Palamar M, et al.

Turkish journal of ophthalmology 2024; (54(5)):251-256 doi:10.4274/tjo.galenos.2024.69705.

Diagnostic approach to limbal stem cell deficiency.

Lent-Schochet D, Akbar M, Hou JH, Farooq AV

Frontiers in ophthalmology 2024; (4()):1524595 doi:10.3389/fopht.2024.1524595.

Risk Factors for Development of Limbal Stem Cell Deficiency After Acute Ocular Burns.

Kate A, Rajagopal RN, Sharma S, et al.

Current eye research 2025; (50(7)):668-676 doi:10.1080/02713683.2025.2482059.

Stevens-Johnson Syndrome as a Risk Factor for Ocular Surface Squamous Neoplasia in a Pediatric Patient.

Muleiro-Alvarez M, Hernandez-Solis A, Ortiz-Morales G, et al.

Cureus 2025; (17(5)):e83919 doi:10.7759/cureus.83919.

Corneal irregularity of the anterior and posterior surface in patients with limbal stem cell deficiency evaluated with anterior-segment optical coherence tomography.

Goto H, Ono T, Taketani Y, et al.

Japanese journal of ophthalmology 2025; (69(5)):708-716 doi:10.1007/s10384-025-01242-y.

The role of limbal stem cells on neurotrophic cornea.

Ciftci MD, Dereli Can G, Gurdal M, Barut Selver O

Clinical & experimental optometry 2025; 1-7 doi:10.1080/08164622.2025.2561862.

Clinical anatomy: cornea and ocular surface.

Ozkan O, Utine CA

Medical hypothesis, discovery & innovation ophthalmology journal 2025; (14(3)):60-72 doi:10.51329/mehdiophthal1524.

Limbal Epithelial Cells Detected in Stage III Limbal Stem Cell Deficiency by Multimodal Anterior Segment Imaging.

Bonnet C, Maalhaghfard M, Deng SX

American journal of ophthalmology 2026; (283()):91-99 doi:10.1016/j.ajo.2025.11.041.