Research & Literature

Gestational Trophoblastic Disease Diagnosis Delayed by the Hook Effect.

Cormano J, Mackay G, Holschneider C

Obstetrics and gynecology 2015; (126(4)):811-814 doi:10.1097/AOG.0000000000000860.

Approach to lymph node metastases in sporadic medullary thyroid carcinoma An istitutional experience.

Polistena A, Monacelli M, Lucchini R, et al.

Annali italiani di chirurgia 2015; (86()):390-5.

A comprehensive overview of the role of the RET proto-oncogene in thyroid carcinoma.

Romei C, Ciampi R, Elisei R

Nature reviews. Endocrinology 2016; (12(4)):192-202 doi:10.1038/nrendo.2016.11.

Comprehensive Genomic Profiling of Clinically Advanced Medullary Thyroid Carcinoma.

Heilmann AM, Subbiah V, Wang K, et al.

Oncology 2016; (90(6)):339-46 doi:10.1159/000445978.

Trends in the presentation, treatment, and survival of patients with medullary thyroid cancer over the past 30 years.

Randle RW, Balentine CJ, Leverson GE, et al.

Surgery 2017; (161(1)):137-146 doi:10.1016/j.surg.2016.04.053.

Is new American Thyroid Association risk classification for hereditary medullary thyroid carcinoma applicable to Chinese patients? A single-center study.

Zhang X, Yan D, Wang J, et al.

Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2017; (29(3)):223-230 doi:10.21147/j.issn.1000-9604.2017.03.08.

Prophylactic thyroidectomy in children with multiple endocrine neoplasia type 2.

Prete FP, Abdel-Aziz T, Morkane C, et al.

The British journal of surgery 2018; (105(10)):1319-1327 doi:10.1002/bjs.10856.

Update on multiple endocrine neoplasia Type 1 and 2.

Al-Salameh A, Baudry C, Cohen R

Presse medicale (Paris, France : 1983) 2018; (47(9)):722-731 doi:10.1016/j.lpm.2018.03.005.

Educational Case: Endocrine Neoplasm: Medullary Thyroid Carcinoma.

Segura S, Ramos-Rivera G, Suhrland M

Academic pathology 2018; (5()):2374289518775722 doi:10.1177/2374289518775722.

Falsely decreased ferritin concentrations in two patients with haemophagocytic lymphohistiocytosis: A case report.

Roozen G, Revet I, Raymakers R, Kemperman H

Annals of clinical biochemistry 2019; (56(1)):179-182 doi:10.1177/0004563218793166.

Static Prognostic Factors and Appropriate Surgical Designs for Patients with Medullary Thyroid Carcinoma: The Second Report from a Single-Institution Study in Japan.

Ito Y, Miyauchi A, Kihara M, et al.

World journal of surgery 2018; (42(12)):3954-3966 doi:10.1007/s00268-018-4738-z.

Genetic characterization of medullary thyroid cancer in childhood survivors of the Chernobyl accident.

Fisher SB, Cote GJ, Bui-Griffith JH, et al.

Surgery 2019; (165(1)):58-63 doi:10.1016/j.surg.2018.08.029.

[The patterns of cervical lymph node metastasis and the surgical treatment for untreated medullary thyroid carcinoma].

Jin LS

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery 2018; (32(19)):1504-1506 doi:10.13201/j.issn.1001-1781.2018.19.016.

Natural history, treatment, and long-term follow up of patients with multiple endocrine neoplasia type 2B: an international, multicentre, retrospective study.

Castinetti F, Waguespack SG, Machens A, et al.

The lancet. Diabetes & endocrinology 2019; (7(3)):213-220 doi:10.1016/S2213-8587(18)30336-X.

Medullary Thyroid Carcinoma: Why Is Specialization Mandatory?

Weber T

Visceral medicine 2018; (34(6)):419-421 doi:10.1159/000493809.

Calcitonin negative Medullary Thyroid Carcinoma: a challenging diagnosis or a medical dilemma?

Gambardella C, Offi C, Patrone R, et al.

BMC endocrine disorders 2019; (19(Suppl 1)):45 doi:10.1186/s12902-019-0367-2.

Calcitonin-negative medullary thyroid carcinoma: the 'triple-negative' phenotype.

Murphy DC, Johnson SJ, Aspinall S

Annals of the Royal College of Surgeons of England 2020; (102(3)):e63-e66 doi:10.1308/rcsann.2019.0153.

The prognostic value of lymph node ratio in Medullary thyroid carcinoma: A multi-center study.

Rozenblat T, Hirsch D, Robenshtok E, et al.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2020; (46(11)):2023-2028 doi:10.1016/j.ejso.2020.04.016.

A Proposed Grading Scheme for Medullary Thyroid Carcinoma Based on Proliferative Activity (Ki-67 and Mitotic Count) and Coagulative Necrosis.

Fuchs TL, Nassour AJ, Glover A, et al.

The American journal of surgical pathology 2020; (44(10)):1419-1428 doi:10.1097/PAS.0000000000001505.

Neoadjuvant selpercatinib for advanced medullary thyroid cancer.

Jozaghi Y, Zafereo M, Williams MD, et al.

Head & neck 2021; (43(1)):E7-E12 doi:10.1002/hed.26527.

Crude annual incidence rate of medullary thyroid cancer and RET mutation frequency.

Milićević S, Bergant D, Žagar T, Perić B

Croatian medical journal 2021; (62(2)):110-119.

Medullary thyroid carcinoma in children: current state of the art and future perspectives.

Kiriakopoulos A, Dimopoulou A, Nastos C, et al.

Journal of pediatric endocrinology & metabolism : JPEM 2022; (35(1)):1-10 doi:10.1515/jpem-2021-0502.

Outcome of Patients with Locally Advanced Metastatic Medullary Thyroid Cancer and Induction Therapy with Tyrosine Kinase Inhibitors in Slovenia.

Grasic Kuhar C, Lozar T, Besic N, Music Marolt M

Advances in therapy 2021; (38(12)):5684-5699 doi:10.1007/s12325-021-01940-2.

International Medullary Thyroid Carcinoma Grading System: A Validated Grading System for Medullary Thyroid Carcinoma.

Xu B, Fuchs TL, Ahmadi S, et al.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2022; (40(1)):96-104 doi:10.1200/JCO.21.01329.

Medullary thyroid cancer with ectopic Cushing's syndrome: A multicentre case series.

Koehler VF, Fuss CT, Berr CM, et al.

Clinical endocrinology 2022; (96(6)):847-856 doi:10.1111/cen.14617.

Utilizing the circulating tumor markers in diagnosis and management of medullary thyroid cancer.

Zarkesh M, Arab N, Tavangar SM, et al.

Pathology, research and practice 2022; (229()):153694 doi:10.1016/j.prp.2021.153694.

"Triple-negative" non-secretory medullary thyroid cancer: uncommon pathological findings in a rare disease.

Martínez-Montoro JI, Gómez-Pérez AM, Gallego E, et al.

Archives of medical science : AMS 2022; (18(3)):825-828 doi:10.5114/aoms/147431.

RET c.1901G>A and Novel SLC12A3 Mutations in Familial Pheochromocytomas

Zhao L, Yang KQ, Fan P, et al.

Genes 2022; (13(5)) doi:10.3390/genes13050864.

Rapid and long-lasting response to selpercatinib of paraneoplastic Cushing's syndrome in medullary thyroid carcinoma.

Sitbon M, Chou P, Bengaly S, et al.

European thyroid journal 2022; (11(6)).

Management of lymph nodes in medullary thyroid carcinoma: A review.

Shaghaghi A, Salari A, Jalaeefar A, Shirkhoda M

Annals of medicine and surgery (2012) 2022; (81()):104538 doi:10.1016/j.amsu.2022.104538.

A Contemporary Review of the Treatment of Medullary Thyroid Carcinoma in the Era of New Drug Therapies.

Seib CD, Beck TC, Kebebew E

Surgical oncology clinics of North America 2023; (32(2)):233-250 doi:10.1016/j.soc.2022.10.002.

Phase 3 Trial of Selpercatinib in Advanced RET-Mutant Medullary Thyroid Cancer.

Hadoux J, Elisei R, Brose MS, et al.

The New England journal of medicine 2023; (389(20)):1851-1861 doi:10.1056/NEJMoa2309719.

Serum Biochemical Markers for Medullary Thyroid Carcinoma: An Update.

Liu S, Zhao H, Li X

Cancer management and research 2024; (16()):299-310 doi:10.2147/CMAR.S440477.

Management of Advanced Medullary Thyroid Carcinoma: Current Systemic Therapy Options.

Jara MA

Critical reviews in oncogenesis 2024; (29(3)):83-90 doi:10.1615/CritRevOncog.2024051588.

Medullary Thyroid Cancer: Epidemiology and Characteristics According to Data From the Marne-Ardennes Register 1975-2018.

Caillé S, Debreuve-Theresette A, Vitellius G, et al.

Journal of the Endocrine Society 2024; (8(6)):bvae084 doi:10.1210/jendso/bvae084.

Histopathology of C Cells and Medullary Thyroid Carcinoma.

Cameselle-Teijeiro JM, Sobrinho-Simões M

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 2025; (223()):9-50 doi:10.1007/978-3-031-80396-3_2.

Epidemiology, Clinical Presentation, and Diagnosis of Medullary Thyroid Carcinoma.

Raue F, Frank-Raue K

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 2025; (223()):93-127 doi:10.1007/978-3-031-80396-3_4.

High-dose Hook Effect in a Case of Giant Prolactinoma Confounded by Acute Kidney Injury.

Lam A, Prosser C, Chik CL

JCEM case reports 2025; (3(8)):luaf136 doi:10.1210/jcemcr/luaf136.

Highly-selected sporadic, apparently unifocal cN0 MTC may benefit from unilateral surgery. A proof of concept in a high-volume institution.

Rossi L, Matrone A, Torregrossa L, et al.

Surgery 2026; (189()):109699 doi:10.1016/j.surg.2025.109699.

Untying the Next Genetic Thread in a Family With MEN2A Syndrome: A Case Report.

Shrestha R, Adil MA, Basnet B, et al.

Clinical case reports 2025; (13(10)):e71065 doi:10.1002/ccr3.71065.

Predictors of Distant Metastasis in Patients with Medullary Thyroid Carcinoma.

Ros-Madrid I, Febrero B, Cano-Mármol RP, et al.

Cancers 2025; (17(19)) doi:10.3390/cancers17193193.

Immunohistochemical expression of Ki-67, INSM1, and SSTR2A in medullary thyroid carcinoma: correlation with tumour size, vascular invasion, and biochemical outcome.

Rossi ED, Raia S, Maratta M, et al.

Virchows Archiv : an international journal of pathology 2025; doi:10.1007/s00428-025-04287-z.

Validation of the International Medullary Thyroid Carcinoma Grading System in Patients with Distant Metastases.

Porcelli T, Moog S, Bani MA, et al.

Thyroid : official journal of the American Thyroid Association 2025; (35(11)):1268-1276 doi:10.1177/10507256251388028.

Late-Onset Gastrointestinal Manifestations of Multiple Endocrine Neoplasia Type 2B (MEN2B): Diffuse Ganglioneuromatosis Causing Megacolon.

Rana M, Hussain S, Osman S, Anant P

Cureus 2025; (17(12)):e98366 doi:10.7759/cureus.98366.

Calcitonin-negative medullary thyroid carcinoma combined with multifocal papillary thyroid carcinoma: a case report and literature review.

Ma W, Lin L, Zhang W, et al.

BMC endocrine disorders 2026; (26(1)):52 doi:10.1186/s12902-026-02172-7.

Widespread Skeletal Metastases in Medullary Thyroid Carcinoma: Diagnostic Superiority of 68Ga-FAPI PET/CT Over Somatostatin Receptor-Targeted Imaging.

Taheri F, Tanha AS, Aboutorabi RB, et al.

Clinical nuclear medicine 2026; doi:10.1097/RLU.0000000000006450.

De novo mutation of the RET proto-oncogene revealing multiple endocrine neoplasia type 2A: a sporadic case from Western Algeria.

Chami A, Romanet P, Mohammedi F, et al.

The Gulf journal of oncology 2025; (1(49)):35-39.