Research & Literature

Madelung disease.

Zielińska-Kaźmierska B, Lewicki M, Manowska B

Postepy dermatologii i alergologii 2015; (32(5)):400-3 doi:10.5114/pdia.2015.54750.

IMAGES IN CLINICAL MEDICINE. Madelung's Disease.

Nisi G, Sisti A

The New England journal of medicine 2016; (374(6)):572 doi:10.1056/NEJMicm1503861.

Symmetric Lipomatosis Arising in the Tongue Presenting as Macroglossia and Articulatory Disorder.

Kudoh M, Omura K, Satsukawa A, et al.

Case reports in otolaryngology 2016; (2016()):2061649 doi:10.1155/2016/2061649.

Homozygous LIPE mutation in siblings with multiple symmetric lipomatosis, partial lipodystrophy, and myopathy.

Zolotov S, Xing C, Mahamid R, et al.

American journal of medical genetics. Part A 2017; (173(1)):190-194 doi:10.1002/ajmg.a.37880.

Madelung Disease.

Chen HW, Chen HW, Chen HL, Lai CC

The American journal of the medical sciences 2016; (352(6)):654 doi:10.1016/j.amjms.2016.06.009.

Madelung's Disease: Revision of 59 Surgical Cases.

Pinto CI, Carvalho PJ, Correia MM

Aesthetic plastic surgery 2017; (41(2)):359-368 doi:10.1007/s00266-016-0759-x.

Do you know this syndrome? Type 2 benign symmetric lipomatosis (Launois-Bensaude).

Esposito AC, Munhoz T, Abbade LP, Miot HA

Anais brasileiros de dermatologia 2016; (91(6)):840-841 doi:10.1590/abd1806-4841.20164744.

A case of severe obstructive sleep apnoea in Madelung's disease treated by lateral pharyngoplasty.

Pinto V, Morselli PG, Tassone D, Piccin O

The Journal of laryngology and otology 2017; (131(9)):834-837 doi:10.1017/S0022215117001062.

Beyond cervical lipomas: myoclonus, gait disorder and multisystem involvement leading to mitochondrial disease.

López-Blanco R, Rojo-Sebastián A, Torregrosa-Martínez MH, Blazquez A

BMJ case reports 2017; (2017()) doi:10.1136/bcr-2016-218861.

Multiple Symmetric Lipomatosis.

Prahlow SP, Kosciuk P, Prahlow JA

Journal of forensic sciences 2018; (63(1)):312-315 doi:10.1111/1556-4029.13536.

Multiple symmetric lipomatosis.

Hudzik B, Szkodziński J, Gąsior M, Zubelewicz-Szkodzińska B

Polish archives of internal medicine 2017; (127(6)):450-451 doi:10.20452/pamw.4050.

Lipomatoses.

Al Ghazal P, Grönemeyer LL, Schön MP

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2018; (16(3)):313-327 doi:10.1111/ddg.13460.

Multiple sclerosis.

Thompson AJ, Baranzini SE, Geurts J, et al.

Lancet (London, England) 2018; (391(10130)):1622-1636 doi:10.1016/S0140-6736(18)30481-1.

Madelung's Disease: Lipectomy or Liposuction?

Chen CY, Fang QQ, Wang XF, et al.

BioMed research international 2018; (2018()):3975974 doi:10.1155/2018/3975974.

Adipose tissue-derived stem cells from affected and unaffected areas in patients with multiple symmetric lipomatosis show differential regulation of mTOR pathway genes.

Felthaus O, Schön T, Schiltz D, et al.

Clinical hemorheology and microcirculation 2018; (69(1-2)):141-151 doi:10.3233/CH-189107.

Multiple Symmetric Lipomatosis: New Classification System Based on the Largest German Patient Cohort.

Schiltz D, Anker A, Ortner C, et al.

Plastic and reconstructive surgery. Global open 2018; (6(4)):e1722 doi:10.1097/GOX.0000000000001722.

MFN2-associated lipomatosis: Clinical spectrum and impact on adipose tissue.

Capel E, Vatier C, Cervera P, et al.

Journal of clinical lipidology 2018; (12(6)):1420-1435 doi:10.1016/j.jacl.2018.07.009.

Madelung lipomatosis presenting as a manifestation of myoclonic epilepsy with ragged red fibers (MERRF) syndrome.

Gilson RC, Osswald S

JAAD case reports 2018; (4(8)):822-823 doi:10.1016/j.jdcr.2018.05.004.

Multiple Symmetric Lipomatosis (Madelung Disease) in a Large Canadian Family With the Mitochondrial MTTK c.8344A>G Variant.

Perera U, Kennedy BA, Hegele RA

Journal of investigative medicine high impact case reports 2018; (6()):2324709618802867 doi:10.1177/2324709618802867.

Madelung's disease.

López-García S, Vizán-Caravaca JR, García-Cortacero E

Medicina clinica 2019; (152(12)):517 doi:10.1016/j.medcli.2018.07.022.

Madelung's disease - progressive, excessive, and symmetrical deposition of adipose tissue in the subcutaneous layer: case report and literature review.

Szewc M, Sitarz R, Moroz N, et al.

Diabetes, metabolic syndrome and obesity : targets and therapy 2018; (11()):819-825 doi:10.2147/DMSO.S181154.

Madelung disease: A case report.

Gao H, Xin ZY, Yin X, et al.

Medicine 2019; (98(3)):e14116 doi:10.1097/MD.0000000000014116.

Multiple Symmetric Lipomatosis in a Chronic Male Alcoholic.

Chen SL, Hu CY, Chan KC

Ear, nose, & throat journal 2019; (98(2)):79-80 doi:10.1177/0145561318825065.

Calcyphosine-like (CAPSL) is regulated in Multiple Symmetric Lipomatosis and is involved in Adipogenesis.

Lindner A, Marbach F, Tschernitz S, et al.

Scientific reports 2019; (9(1)):8444 doi:10.1038/s41598-019-44382-1.

Madelung's Disease Leading to Presenile Dementia in a Non-alcoholic Patient.

El Hasbani G, Assaker R, Nithisoontorn S, et al.

Medical archives (Sarajevo, Bosnia and Herzegovina) 2019; (73(4)):285-287 doi:10.5455/medarh.2019.73.285-287.

Adipose Tissue in Multiple Symmetric Lipomatosis Shows Features of Brown/Beige Fat.

Schiltz D, Tschernitz S, Ortner C, et al.

Aesthetic plastic surgery 2020; (44(3)):855-861 doi:10.1007/s00266-020-01666-6.

A case of Madelung's disease presenting with obstructive sleep apnea.

Segsarnviriya C, Chirakalwasan N

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2020; (16(9)):1603-1605 doi:10.5664/jcsm.8622.

Multiple symmetric lipomatosis with secondary laryngeal obstruction: A case report.

Cui Y, Cui X, Gao S, et al.

Medicine 2020; (99(27)):e21014 doi:10.1097/MD.0000000000021014.

Madelung Disease Treated With Deoxycholic Acid.

Rodriguez M, Beal BT, Khetarpal S, Vidimos A

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2021; (47(6)):879-880 doi:10.1097/DSS.0000000000002722.

A case report of Multiple Symmetric Lipomatosis (MSL) in an East Asian Female.

Jung K, Lee S

BMC women's health 2020; (20(1)):200 doi:10.1186/s12905-020-01055-w.

LIPE-related lipodystrophic syndrome: clinical features and disease modeling using adipose stem cells.

Sollier C, Capel E, Aguilhon C, et al.

European journal of endocrinology 2021; (184(1)):155-168.

Dercum's Disease: A Case Report of a Patient Having Both Type 1 and Type 2 Dercum's Disease.

Moattari C, Giovane RA, DiGiovanni Kinsely S

Case reports in dermatological medicine 2020; (2020()):6129706 doi:10.1155/2020/6129706.

Bilateral symmetric lipomatosis of the orbit in Madelung's disease.

Lumyongsatien M, Selva D

Orbit (Amsterdam, Netherlands) 2022; (41(2)):268-270 doi:10.1080/01676830.2020.1852261.

Madelung Disease Epidemiology and Clinical Characteristics: a Systemic Review.

Liu Q, Lyu H, Xu B, Lee JH

Aesthetic plastic surgery 2021; (45(3)):977-986 doi:10.1007/s00266-020-02083-5.

Madelung's disease. Two case reports with pseudoathletic appearance.

Miraglia E, Moliterni E, Iacovino C, et al.

La Clinica terapeutica 2021; (172(3)):190-192 doi:10.7417/CT.2021.2311.

Madelung's disease in a non-alcoholic Ethiopian male patient mistaken for obesity: a case report.

Zewde YZ

BMC endocrine disorders 2021; (21(1)):142 doi:10.1186/s12902-021-00803-9.

Madelung's disease with alcoholic liver disease and acute kidney injury: A case report.

Wu L, Jiang T, Zhang Y, et al.

World journal of clinical cases 2021; (9(27)):8199-8206 doi:10.12998/wjcc.v9.i27.8199.

Multiple symmetric and multiple familial lipomatosis.

Lemaitre M, Chevalier B, Jannin A, et al.

Presse medicale (Paris, France : 1983) 2021; (50(3)):104077 doi:10.1016/j.lpm.2021.104077.

A case report of Madelung's disease in China.

Wanke J, Yongjing F

Radiology case reports 2022; (17(2)):320-325 doi:10.1016/j.radcr.2021.10.035.

Diagnostic and surgical challenges of progressive neck and upper back painless masses in Madelung's disease: A case report and review of literature.

Yan YJ, Zhou SQ, Li CQ, Ruan Y

World journal of clinical cases 2022; (10(1)):361-370 doi:10.12998/wjcc.v10.i1.361.

Late Night Salivary Cortisol in the diagnosis of neoplastic hypercortisolism (including cyclic Cushing's syndrome).

Raff H

Pituitary 2022; (25(5)):698-700 doi:10.1007/s11102-022-01214-2.

Prevertebral fat in Madelung disease mimicking cervical spine injury: A case report.

Hirunpat P, Panyaping T, Charoensri A, et al.

The neuroradiology journal 2023; (36(2)):241-244 doi:10.1177/19714009221128660.

A mouse model of human mitofusin-2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion.

Mann JP, Duan X, Patel S, et al.

eLife 2023; (12()).

Lipectomy for madelung disease using tumescent technique: a cross-sectional study.

Duc NQ, Tien NP, Tu NT, et al.

Annals of medicine and surgery (2012) 2023; (85(6)):2550-2558 doi:10.1097/MS9.0000000000000806.

Shedding Light on Multiple Symmetric Lipomatosis: An Overlooked Syndrome in the Evaluation of Obesity.

Saraiva M, Ferreira LMD, Carvalho R

The American journal of case reports 2023; (24()):e941751 doi:10.12659/AJCR.941751.

A Chinese patient with Madelung's disease and alcoholic cardiomyopathy: a case report and literature review.

Zhao H, Ma XL, Yu K, et al.

European review for medical and pharmacological sciences 2024; (28(13)):3905-3911 doi:10.26355/eurrev_202407_36522.

Could Madelung disease be a cause of stroke? A rare case report.

Tosunoğlu B, Altıkardeş M, Arık EP, et al.

Folia medica 2024; (66(4)):583-586 doi:10.3897/folmed.66.e116329.

Madelung disease with postoperative priapism and multiple venous thromboses: case report and literature review.

Guo L, Li W, Xu X, Xiao H

Frontiers in cardiovascular medicine 2024; (11()):1449556 doi:10.3389/fcvm.2024.1449556.

Research progress on the pathogenesis of multiple symmetrical lipomatosis.

Hu B, Wang Z, Ma T, et al.

Adipocyte 2024; (13(1)):2416681 doi:10.1080/21623945.2024.2416681.

A Case Report of Madelung's Disease in Romania.

Cucu AI, Sava A, Bobu AM, et al.

Diagnostics (Basel, Switzerland) 2025; (15(4)) doi:10.3390/diagnostics15040459.

Madelung's disease -a case series from a single-center experience.

Łącka M, Wojciechowska J, Bernecka P, et al.

Frontiers in surgery 2025; (12()):1636822 doi:10.3389/fsurg.2025.1636822.

Case Report of a patient with Madelung's disease combined with alcoholic liver disease and liver cirrhosis.

Gu Z, Hao Y, Duan J, Zhao K

Frontiers in medicine 2025; (12()):1695921 doi:10.3389/fmed.20251695921.