Research & Literature

Intestinal strictures post-necrotising enterocolitis: clinical profile and risk factors.

Phad N, Trivedi A, Todd D, Lakkundi A

Journal of neonatal surgery 2014; (3(4)):44.

Risk factors associated with postnecrotizing enterocolitis strictures in infants.

Heida FH, Loos MH, Stolwijk L, et al.

Journal of pediatric surgery 2016; (51(7)):1126-30.

Necrotizing enterocolitis is associated with earlier achievement of enteral autonomy in children with short bowel syndrome.

Sparks EA, Khan FA, Fisher JG, et al.

Journal of pediatric surgery 2016; (51(1)):92-5.

Relationship between Packed Red Blood Cell Transfusion and Severe Form of Necrotizing Enterocolitis: A Case Control Study.

Garg PM, Ravisankar S, Bian H, et al.

Indian pediatrics 2015; (52(12)):1041-5 doi:10.1007/s13312-015-0770-3.

Impact of Donor Milk Availability on Breast Milk Use and Necrotizing Enterocolitis Rates.

Kantorowska A, Wei JC, Cohen RS, et al.

Pediatrics 2016; (137(3)):e20153123 doi:10.1542/peds.2015-3123.

Necrotizing Enterocolitis and Human Milk Feeding: A Systematic Review.

Cacho NT, Parker LA, Neu J

Clinics in perinatology 2017; (44(1)):49-67 doi:10.1016/j.clp.2016.11.009.

Animal models for studying epithelial barriers in neonatal necrotizing enterocolitis, inflammatory bowel disease and colorectal cancer.

Xing T, Camacho Salazar R, Chen YH

Tissue barriers 2017; (5(4)):e1356901 doi:10.1080/21688370.2017.1356901.

Vitamin D ameliorates neonatal necrotizing enterocolitis via suppressing TLR4 in a murine model.

Shi Y, Liu T, Zhao X, et al.

Pediatric research 2018; (83(5)):1024-1030 doi:10.1038/pr.2017.329.

Incidence of neonatal necrotising enterocolitis in high-income countries: a systematic review.

Battersby C, Santhalingam T, Costeloe K, Modi N

Archives of disease in childhood. Fetal and neonatal edition 2018; (103(2)):F182-F189 doi:10.1136/archdischild-2017-313880.

Improving Growth for Infants ≤1250 Grams Receiving an Exclusive Human Milk Diet.

Huston RK, Markell AM, McCulley EA, et al.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 2018; (33(5)):671-678 doi:10.1002/ncp.10054.

Oxidative Stress and Necrotizing Enterocolitis: Pathogenetic Mechanisms, Opportunities for Intervention, and Role of Human Milk.

Aceti A, Beghetti I, Martini S, et al.

Oxidative medicine and cellular longevity 2018; (2018()):7397659 doi:10.1155/2018/7397659.

Enteral feeding composition and necrotizing enterocolitis.

Cruz D, Bazacliu C

Seminars in fetal & neonatal medicine 2018; (23(6)):406-410 doi:10.1016/j.siny.2018.08.003.

Probiotics and the prevention of necrotizing enterocolitis.

Underwood MA

Journal of pediatric surgery 2019; (54(3)):405-412 doi:10.1016/j.jpedsurg.2018.08.055.

Management of NEC: Surgical Treatment and Role of Traditional X-ray Versus Ultrasound Imaging, Experience of a Single Centre.

De Bernardo G, Sordino D, De Chiara C, et al.

Current pediatric reviews 2019; (15(2)):125-130 doi:10.2174/1573396314666181102122626.

Arguments for routine administration of probiotics for NEC prevention.

Underwood MA

Current opinion in pediatrics 2019; (31(2)):188-194 doi:10.1097/MOP.0000000000000732.

Role of Abdominal US in Diagnosis of NEC.

Kim JH

Clinics in perinatology 2019; (46(1)):119-127 doi:10.1016/j.clp.2018.10.006.

Necrotizing Enterocolitis: Long Term Complications.

Bazacliu C, Neu J

Current pediatric reviews 2019; (15(2)):115-124 doi:10.2174/1573396315666190312093119.

Solely human milk diets for preterm infants.

Taylor SN

Seminars in perinatology 2019; (43(7)):151158 doi:10.1053/j.semperi.2019.06.006.

Application of abdominal sonography in diagnosis of infants with necrotizing enterocolitis.

Chen S, Hu Y, Liu Q, et al.

Medicine 2019; (98(28)):e16202 doi:10.1097/MD.0000000000016202.

Bifidobacterium and Lactobacillus for preventing necrotizing enterocolitis in very-low-birth-weight preterm infants: a systematic review and meta-analysis.

Jiao X, Fu MD, Wang YY, et al.

World journal of pediatrics : WJP 2020; (16(2)):135-142 doi:10.1007/s12519-019-00297-5.

The Role of Gastrointestinal-Related Fatty Acid-Binding Proteins as Biomarkers in Gastrointestinal Diseases.

Ho SSC, Keenan JI, Day AS

Digestive diseases and sciences 2020; (65(2)):376-390 doi:10.1007/s10620-019-05841-x.

Contemporary Outcomes for Infants with Necrotizing Enterocolitis-A Systematic Review.

Jones IH, Hall NJ

The Journal of pediatrics 2020; (220()):86-92.e3 doi:10.1016/j.jpeds.2019.11.011.

Trends in incidence and outcomes of necrotizing enterocolitis over the last 12 years: A multicenter cohort analysis.

Han SM, Hong CR, Knell J, et al.

Journal of pediatric surgery 2020; (55(6)):998-1001 doi:10.1016/j.jpedsurg.2020.02.046.

Urinary I-FABP, L-FABP, TFF-3, and SAA Can Diagnose and Predict the Disease Course in Necrotizing Enterocolitis at the Early Stage of Disease.

Coufal S, Kokesova A, Tlaskalova-Hogenova H, et al.

Journal of immunology research 2020; (2020()):3074313 doi:10.1155/2020/3074313.

Lactate and intestinal fatty acid binding protein as essential biomarkers in neonates with necrotizing enterocolitis: ultrasonographic and surgical considerations.

El-Abd Ahmed A, Hassan MH, Abo-Halawa N, et al.

Pediatrics and neonatology 2020; (61(5)):481-489 doi:10.1016/j.pedneo.2020.03.015.

Incidence, Treatment, and Outcome Trends of Necrotizing Enterocolitis in Preterm Infants: A Multicenter Cohort Study.

Zozaya C, García González I, Avila-Alvarez A, et al.

Frontiers in pediatrics 2020; (8()):188 doi:10.3389/fped.2020.00188.

Earlier re-initiation of enteral feeding after necrotizing enterocolitis decreases recurrence or stricture: a systematic review and meta-analysis.

Patel EU, Wilson DA, Brennan EA, et al.

Journal of perinatology : official journal of the California Perinatal Association 2020; (40(11)):1679-1687 doi:10.1038/s41372-020-0722-1.

Challenges in diagnosing necrotizing enterocolitis.

Kim JH, Sampath V, Canvasser J

Pediatric research 2020; (88(Suppl 1)):16-20 doi:10.1038/s41390-020-1090-4.

Abnormal Splanchnic Regional Saturations in a Preterm Infant That Developed Necrotizing Enterocolitis Following a Red Blood Cell Transfusion.

Baserga M, Reich B, Braski K

Advances in neonatal care : official journal of the National Association of Neonatal Nurses 2020; (20(5)):401-405 doi:10.1097/ANC.0000000000000711.

Portal gas in neonates; is it always surgical? A case report.

Altokhais TI

World journal of clinical cases 2020; (8(17)):3804-3807 doi:10.12998/wjcc.v8.i17.3804.

Portal venous gas resulting from umbilical vein catheterization in a very-low-birth-weight infant with no interruption in early feeding.

Wang J, Yue G, Yang H, et al.

Pediatric investigation 2021; (5(2)):155-158 doi:10.1002/ped4.12236.

The role of ultrasound in necrotizing enterocolitis.

Hwang M, Tierradentro-García LO, Dennis RA, Anupindi SA

Pediatric radiology 2022; (52(4)):702-715 doi:10.1007/s00247-021-05187-5.

The effect of daily probiotics on the incidence and severity of necrotizing enterocolitis in infants with very low birth weight.

Que J, Van Oerle R, Albersheim S, et al.

Canadian journal of surgery. Journal canadien de chirurgie 2021; (64(6)):E644-E649 doi:10.1503/cjs.016920.

The Association of Human Milk Feeding With Short-Term Health Outcomes Among Chinese Very/Extremely Low Birth Weight Infants.

Peng W, Han J, Li S, et al.

Journal of human lactation : official journal of International Lactation Consultant Association 2022; (38(4)):670-677 doi:10.1177/08903344221078237.

Necrotizing Enterocolitis and Its Predictors Among Preterm Neonates Admitted in Neonatal Intensive Care Units of Gurage Zone Public Hospitals, Southwest Ethiopia, 2021.

Chekole Temere B, Aynalem Mewahegn A, Tefera Zewudie B, et al.

Pediatric health, medicine and therapeutics 2022; (13()):95-102 doi:10.2147/PHMT.S353663.

The inhibition of enterocyte proliferation by lithocholic acid exacerbates necrotizing enterocolitis through downregulating the Wnt/β-catenin signalling pathway.

Feng Z, Jia C, Lin X, et al.

Cell proliferation 2022; (55(5)):e13228 doi:10.1111/cpr.13228.

Analysis of Factors Influencing Outcomes in Preterm Infants With Necrotizing Enterocolitis.

Han J, Liu G, Yu M, et al.

Frontiers in pediatrics 2022; (10()):768107 doi:10.3389/fped.2022.768107.

Neurologic Consequences of Neonatal Necrotizing Enterocolitis.

Berken JA, Chang J

Developmental neuroscience 2022; (44(4-5)):295-308 doi:10.1159/000525378.

Utility of transforming growth factor beta-1 in diagnosis of neonatal necrotizing enterocolitis.

Almonaem ERA, Almotaleb GSA, Alhameed MHA, El-Shimi OS

Journal of neonatal-perinatal medicine 2022; (15(4)):795-801 doi:10.3233/NPM-210973.

Predictive Factors for Surgical Intervention in Neonates with Necrotizing Enterocolitis: A Retrospective Study.

Yu L, Liu C, Du Q, Ma L

Frontiers in surgery 2022; (9()):889321 doi:10.3389/fsurg.2022.889321.

LncRNA and mRNA profiles of human milk-derived exosomes and their possible roles in protecting against necrotizing enterocolitis.

Yan X, Liu L, Yao S, et al.

Food & function 2022; (13(24)):12953-12965 doi:10.1039/d2fo01866g.

Succinate aggravates intestinal injury in mice with necrotizing enterocolitis.

Yan XL, Liu XC, Zhang YN, et al.

Frontiers in cellular and infection microbiology 2022; (12()):1064462 doi:10.3389/fcimb.2022.1064462.

Lactate acid level and prognosis of neonatal necrotizing enterocolitis: a retrospective cohort study based on pediatric-specific critical care database.

Wang Y, Lai L, Zhang Q, Zheng L

Jornal de pediatria 2023; (99(3)):278-283 doi:10.1016/j.jped.2022.11.005.

Diagnostic efficacy of high-frequency ultrasound and X-ray contrast enema in colonic strictures after necrotizing enterocolitis: a retrospective study.

Hu Y, Jia L, Wang Y, et al.

Pediatric surgery international 2022; (39(1)):56 doi:10.1007/s00383-022-05278-w.

Analysis of Postoperative Outcomes and Extrauterine Growth Retardation in Preterm Infants with Necrotizing Enterocolitis: A Retrospective Study.

Sun Y, Gao Z, Hong W, et al.

American journal of perinatology 2024; (41(S 01)):e1190-e1196 doi:10.1055/s-0042-1760445.

Potential therapeutic effects of milk-derived exosomes on intestinal diseases.

Cui Z, Amevor FK, Zhao X, et al.

Journal of nanobiotechnology 2023; (21(1)):496 doi:10.1186/s12951-023-02176-8.

Development of a Prediction Model for Surgery or Early Mortality at the Time of Initial Assessment for Necrotizing Enterocolitis.

Nayak SP, Sánchez-Rosado M, Reis JD, et al.

American journal of perinatology 2024; (41(12)):1714-1727 doi:10.1055/a-2253-8656.

Neonatal Necrotizing Enterocolitis: An Update on Pathophysiology, Treatment, and Prevention.

Roberts AG, Younge N, Greenberg RG

Paediatric drugs 2024; (26(3)):259-275 doi:10.1007/s40272-024-00626-w.

Investigating transmission patterns among preterm neonates during an outbreak of necrotizing enterocolitis related to Clostridium butyricum using whole-genome sequencing.

Sartor C, Mikrat Y, Grandvuillemin I, et al.

The Journal of hospital infection 2024; (152()):21-27 doi:10.1016/j.jhin.2024.07.009.

Human milk microbiota, oligosaccharide profiles, and infant gut microbiome in preterm infants diagnosed with necrotizing enterocolitis.

Masi AC, Beck LC, Perry JD, et al.

Cell reports. Medicine 2024; (5(9)):101708 doi:10.1016/j.xcrm.2024.101708.

Necrotizing Enterocolitis: A Current Understanding and Challenges for the Future.

De Bernardo G, Vecchione C, Langella C, et al.

Current pediatric reviews 2025; (21(3)):207-212 doi:10.2174/0115733963318619240923062033.

Association of Enteral Feed Type with Neurodevelopmental and Neonatal Outcomes among Infants Born Preterm.

Bando N, Yoon EW, Beltempo M, et al.

The Journal of pediatrics 2025; (281()):114536 doi:10.1016/j.jpeds.2025.114536.

Analysis of early surgical indications and related factors in neonatal necrotizing enterocolitis.

Shang X, Wang H, Liu Y, et al.

Frontiers in pediatrics 2025; (13()):1571921 doi:10.3389/fped.2025.1571921.

Prediction of the need for surgery in infants with necrotizing enterocolitis: A systematic review and meta-analysis.

Xie X, Pei J, Zhang L, Wu Y

Surgery 2025; (185()):109526 doi:10.1016/j.surg.2025.109526.

Necrotizing Enterocolitis: A Comprehensive Review on Toll-like Receptor 4-Mediated Pathophysiology, Clinical, and Therapeutic Insights.

Ishiyama A, Jang HS, Dintaman JM, et al.

Biomedicines 2025; (13(9)) doi:10.3390/biomedicines13092288.

The diagnostic value of abdominal ultrasound in the progression of necrotizing enterocolitis in low-birth-weight neonates.

Jia L, Li Z, Zhu H, et al.

Medicine 2025; (104(43)):e45427 doi:10.1097/MD.0000000000045427.

Cardiorespiratory signatures of necrotizing enterocolitis: a 4-NICU study of very low birth weight infants.

Kausch SL, Vesoulis ZA, Travers CP, et al.

Pediatric research 2025; doi:10.1038/s41390-025-04631-8.

Deep learning feature-based model on abdominal radiography outperforms experts for early necrotizing enterocolitis diagnosis in neonates.

Wu Y, Yang H, Luo X, et al.

European radiology 2026; doi:10.1007/s00330-025-12264-y.