Research & Literature

Effectiveness of silk fabric underwear as an adjuvant tool in the management of vulvar lichen simplex chronicus: results of a double-blind randomized controlled trial.

Corazza M, Borghi A, Minghetti S, et al.

Menopause (New York, N.Y.) 2015; (22(8)):850-6 doi:10.1097/GME.0000000000000410.

[Vulvar pruritus: determination of the most common causes and their treatments].

Carrillo-Meléndrez H, Villamil-Cerda D, Espinoza-Hernández J, Lacy-Niebla RM

Ginecologia y obstetricia de Mexico 2015; (83(3)):179-88.

Inflammatory Vulvar Dermatoses.

Guerrero A, Venkatesan A

Clinical obstetrics and gynecology 2015; (58(3)):464-75 doi:10.1097/GRF.0000000000000125.

Anogenital Pruritus - An Overview.

Swamiappan M

Journal of clinical and diagnostic research : JCDR 2016; (10(4)):WE01-3 doi:10.7860/JCDR/2016/18440.7703.

2016 European guideline for the management of vulval conditions.

van der Meijden WI, Boffa MJ, Ter Harmsel WA, et al.

Journal of the European Academy of Dermatology and Venereology : JEADV 2017; (31(6)):925-941 doi:10.1111/jdv.14096.

Vulvovaginal Issues in Mature Women.

Marnach ML, Torgerson RR

Mayo Clinic proceedings 2017; (92(3)):449-454 doi:10.1016/j.mayocp.2016.10.031.

Vulvar Pruritus and Lichen Simplex Chronicus.

Chibnall R

Obstetrics and gynecology clinics of North America 2017; (44(3)):379-388 doi:10.1016/j.ogc.2017.04.003.

Skin diseases of the vulva: eczematous diseases and contact urticaria.

Sand FL, Thomsen SF

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 2018; (38(3)):295-300 doi:10.1080/01443615.2017.1329283.

Lichen simplex chronicus on the scalp: exuberant clinical, dermoscopic, and histopathological findings.

Muylaert BPB, Borges MT, Michalany AO, Scuotto CRC

Anais brasileiros de dermatologia 2018; (93(1)):108-110 doi:10.1590/abd1806-4841.20186493.

Genital Allergic Contact Dermatitis.

Yale K, Awosika O, Rengifo-Pardo M, Ehrlich A

Dermatitis : contact, atopic, occupational, drug 2018; (29(3)):112-119 doi:10.1097/DER.0000000000000371.

Dermoscopy of Inflammatory Genital Diseases: Practical Insights.

Borghi A, Virgili A, Corazza M

Dermatologic clinics 2018; (36(4)):451-461 doi:10.1016/j.det.2018.05.013.

A systematic review of evidence based treatments for lichen simplex chronicus.

Juarez MC, Kwatra SG

The Journal of dermatological treatment 2021; (32(7)):684-692 doi:10.1080/09546634.2019.1708856.

Putative precancerous lesions of vulvar squamous cell carcinoma.

Jenkins TM, Mills AM

Seminars in diagnostic pathology 2021; (38(1)):27-36 doi:10.1053/j.semdp.2020.09.006.

Psychiatric comorbidity and temperament-character traits of the patients with lichen simplex chronicus: The relation with the symptom severity of the disease.

Yalçın M, Baş A, Ergelen M, et al.

Dermatologic therapy 2020; (33(6)):e14389 doi:10.1111/dth.14389.

Hypertrophic lichen planus of the vulva - A missed diagnosis.

Mahajan R, Jain V, Ninama K, Marfatia YS

Indian journal of sexually transmitted diseases and AIDS 2020; (41(1)):116-118 doi:10.4103/ijstd.IJSTD_51_19.

Common Benign Chronic Vulvar Disorders.

Ringel NE, Iglesia C

American family physician 2020; (102(9)):550-557.

Scabies-induced lichen simplex chronicus misdiagnosed as psychogenic pruritus: a case report.

Emmanuel OM, Karovska AV, Ikedilo O

Journal of medical case reports 2021; (15(1)):80 doi:10.1186/s13256-020-02628-x.

An intriguing case of lichen simplex chronicus in an elderly sub-Saharan African with longstanding scabies and sensory neuropathy.

Nchinda Ngek ES, Nsioge RM, Ngenge MB, Kadia BM

The Pan African medical journal 2019; (34()):124 doi:10.11604/pamj.2019.34.124.19999.

Scalp dysaesthesia and lichen simplex chronicus: diagnostic and therapeutic update with literature review.

Starace M, Iorizzo M, Mandel VD, et al.

Clinical and experimental dermatology 2022; (47(1)):3-8 doi:10.1111/ced.14808.

Scrotal Labia - An Uncommon Presentation of Vulvar Lichen Simplex Chronicus.

Verma SB

Indian dermatology online journal 2021; (12(4)):590-592 doi:10.4103/idoj.IDOJ_896_20.

More than a skin disease: stress, depression, anxiety levels, and serum neurotrophins in lichen simplex chronicus.

Altunay İK, Özkur E, Uğurer E, et al.

Anais brasileiros de dermatologia 2021; (96(6)):700-705 doi:10.1016/j.abd.2021.04.011.

Vulvar Neurodermatitis in a Postmenopausal African-American Patient: A Case Report.

Sanchez A, Gandhi K, Lee B, et al.

Journal of menopausal medicine 2022; (28(1)):42-45 doi:10.6118/jmm.21032.

Lichen Simplex Chronicus Itch: An Update.

Ju T, Vander Does A, Mohsin N, Yosipovitch G

Acta dermato-venereologica 2022; (102()):adv00796 doi:10.2340/actadv.v102.4367.

Effectiveness of 0.1% mometasone furoate under hydrocolloid dressing versus 0.1% mometasone furoate in patients with lichen simplex chronicus.

Lo HL, Ip FC

Skin health and disease 2023; (3(4)):e228 doi:10.1002/ski2.228.

The Importance of p16 and p53 Immunohistochemical Staining in Diagnosing Vulvar Lichen Simplex Chronicus Mimicking Vulvar Intraepithelial Neoplasia with False-Positive Human Papillomavirus Type 66.

Achdiat PA, Widjaya MRH, Rowawi R, et al.

International journal of women's health 2024; (16()):9-16 doi:10.2147/IJWH.S439825.

Evaluating duloxetine for pruritus and psychiatric comorbidities in lichen simplex chronicus.

Shafiyev J, Gahramanov I

Archives of dermatological research 2025; (317(1)):249 doi:10.1007/s00403-024-03775-7.

Diagnosis and management of vulval lesions.

Haigh C, Sun HY, Fischer G

Current opinion in obstetrics & gynecology 2025; (37(5)):317-325 doi:10.1097/GCO.0000000000001054.

Lichen Simplex Chronicus: Clinical Perspectives and Emerging Therapeutic Strategies.

Moshkovich M, Andrade LF, Anderson M, Yosipovitch G

American journal of clinical dermatology 2025; (26(6)):895-903 doi:10.1007/s40257-025-00979-z.

A Retrospective Analysis of Itch Intensity and Comorbidities in Lichen Simplex Chronicus.

Mashoudy KD, Ye-Tay J, Kim S, et al.

Acta dermato-venereologica 2025; (105()):adv43776 doi:10.2340/actadv.v105.43776.

Unraveling the Metabolic Mechanisms and Novel Biomarkers of Vulvar Lichen Simplex Chronicus Using Skin Biopsy and Tape Stripping Samples.

He T, Xu F, Liang J, et al.

Metabolites 2025; (15(9)) doi:10.3390/metabo15090566.

A Rare Complication of Lichen Simplex Chronicus Following Deep Inferior Epigastric Perforator Flap Reconstruction.

Saunders LM, Fung M, Middleton D, et al.

Cureus 2025; (17(10)):e95331 doi:10.7759/cureus.95331.

Resolution of Lichen Simplex Chronicus With Nemolizumab: A Case Report.

Gruzmark FS, Yosipovitch G, Lev-Tov HA

Journal of drugs in dermatology : JDD 2025; (24(12)):1252-1253 doi:10.36849/JDD.9273.

Clinical spectrum and quality of life burden of vulvar lichenoid dermatoses: a cross-sectional study of 1177 patients.

Liu T, Zhang Y, Sun K, et al.

Clinical and experimental dermatology 2026; (51(8)):1449-1457 doi:10.1093/ced/llag103.

Differential Clinical Signatures of Vulvar Lichen Sclerosus, Lichen Planus, and Chronic Lichen Simplex: A Comparative Study in 1355 Patients.

Hu Q, Sun K, Liu L, et al.

Clinical, cosmetic and investigational dermatology 2026; (19()):570982 doi:10.2147/CCID.S570982.

Adjunctive Habit Reversal Therapy in Treatment of Lichen Simplex Chronicus (Neurodermatitis): A Comparative, Pilot Study.

Kansal NK, Anuragi RP, Bhatia R, et al.

Indian journal of dermatology 2026; (71(2)):103-108 doi:10.4103/ijd.ijd_594_24.

Atopic dermatitis reconsidered: Clinical mimics and diagnostic pearls.

Lawrence CN, Karagounis TK, Cohen DE

Journal of the American Academy of Dermatology 2026; (94(5S)):S21-S23 doi:10.1016/j.jaad.2025.10.171.

Machine Learning-Based Self-Induced Scratch Intensity Detection Using Feature Optimization and Multi-Channel Electromyogram Signals for Prevention of Lichenification.

Cheema MO, Akhlaq A, Din ZMU, et al.

Bioengineering (Basel, Switzerland) 2026; (13(7)) doi:10.3390/bioengineering13070787.

Targeting type 2 inflammation in dermatology: mechanisms and clinical implications.

Khalil N, Farhadi L, Yosipovitch G

Frontiers in immunology 2026; (17()):1917593 doi:10.3389/fimmu.2026.1917593.