Research & Literature

A summary of the new GINA strategy: a roadmap to asthma control.

Reddel HK, Bateman ED, Becker A, et al.

The European respiratory journal 2015; (46(3)):622-39 doi:10.1183/13993003.00853-2015.

Supported self-management for asthma.

Pinnock H

Breathe (Sheffield, England) 2015; (11(2)):98-109 doi:10.1183/20734735.015614.

A repeated short educational intervention improves asthma control and quality of life.

Plaza V, Peiró M, Torrejón M, et al.

The European respiratory journal 2015; (46(5)):1298-307 doi:10.1183/13993003.00458-2015.

Ten-year longitudinal study of factors influencing nocturnal asthma symptoms among Asian patients in primary care.

Tan NC, Nadkarni NV, Lye WK, et al.

NPJ primary care respiratory medicine 2015; (25()):15064 doi:10.1038/npjpcrm.2015.64.

Achieving asthma control with ICS/LABA: A review of strategies for asthma management and prevention.

Aalbers R, Vogelmeier C, Kuna P

Respiratory medicine 2016; (111()):1-7.

Addressing the misdiagnosis of asthma in adults: where does it go wrong?

MacNeil J, Loves RH, Aaron SD

Expert review of respiratory medicine 2016; (10(11)):1187-1198 doi:10.1080/17476348.2016.1242415.

The use of mobile applications to support self-management for people with asthma: a systematic review of controlled studies to identify features associated with clinical effectiveness and adherence.

Hui CY, Walton R, McKinstry B, et al.

Journal of the American Medical Informatics Association : JAMIA 2017; (24(3)):619-632 doi:10.1093/jamia/ocw143.

Medications and Recent Patents for Status Asthmaticus in Children.

Hon KLE, Leung AKC

Recent patents on inflammation & allergy drug discovery 2017; (11(1)):12-21 doi:10.2174/1872213X11666170130143524.

Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline.

Kapur VK, Auckley DH, Chowdhuri S, et al.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2017; (13(3)):479-504 doi:10.5664/jcsm.6506.

Addition of anti-leukotriene agents to inhaled corticosteroids for adults and adolescents with persistent asthma.

Chauhan BF, Jeyaraman MM, Singh Mann A, et al.

The Cochrane database of systematic reviews 2017; (3()):CD010347 doi:10.1002/14651858.CD010347.pub2.

Co-morbidities in severe asthma: Clinical impact and management.

Porsbjerg C, Menzies-Gow A

Respirology (Carlton, Vic.) 2017; (22(4)):651-661 doi:10.1111/resp.13026.

Environmental triggers and avoidance in the management of asthma.

Gautier C, Charpin D

Journal of asthma and allergy 2017; (10()):47-56 doi:10.2147/JAA.S121276.

Effectiveness and success factors of educational inhaler technique interventions in asthma & COPD patients: a systematic review.

Klijn SL, Hiligsmann M, Evers SMAA, et al.

NPJ primary care respiratory medicine 2017; (27(1)):24 doi:10.1038/s41533-017-0022-1.

Association of Obstructive Sleep Apnea with Asthma: A Meta-Analysis.

Kong DL, Qin Z, Shen H, et al.

Scientific reports 2017; (7(1)):4088 doi:10.1038/s41598-017-04446-6.

Screening for obstructive sleep apnea syndrome in asthma patients: a prospective study based on Berlin and STOP-Bang questionnaires.

Lu H, Fu C, Li W, et al.

Journal of thoracic disease 2017; (9(7)):1945-1958 doi:10.21037/jtd.2017.06.03.

Level of asthma control and risk factors for poor asthma control among clinic patients seen at a Referral Hospital in Addis Ababa, Ethiopia.

Gebremariam TH, Binegdie AB, Mitiku AS, et al.

BMC research notes 2017; (10(1)):558 doi:10.1186/s13104-017-2887-z.

Review article: gastro-oesophageal reflux disease in asthma and chronic obstructive pulmonary disease.

Broers C, Tack J, Pauwels A

Alimentary pharmacology & therapeutics 2018; (47(2)):176-191 doi:10.1111/apt.14416.

Asthma.

Papi A, Brightling C, Pedersen SE, Reddel HK

Lancet (London, England) 2018; (391(10122)):783-800 doi:10.1016/S0140-6736(17)33311-1.

The association between asthma and obstructive sleep apnea (OSA): A systematic review.

Davies SE, Bishopp A, Wharton S, et al.

The Journal of asthma : official journal of the Association for the Care of Asthma 2019; (56(2)):118-129 doi:10.1080/02770903.2018.1444049.

Asthma action plan for proactive bronchial asthma self-management in adults: a randomized controlled trial.

Farag H, Abd El-Wahab EW, El-Nimr NA, Saad El-Din HA

International health 2018; (10(6)):502-516 doi:10.1093/inthealth/ihy050.

Bronchial hyper-responsiveness: a technical update.

Borak J, Lefkowitz RY, Linde B

Occupational medicine (Oxford, England) 2018; (68(8)):519-522 doi:10.1093/occmed/kqy122.

Impact of a single 10 min education session on asthma control as measured by ACT.

Schuermans D, Hanon S, Wauters I, et al.

Respiratory medicine 2018; (143()):14-17 doi:10.1016/j.rmed.2018.08.003.

Effects of physical exercise training on nocturnal symptoms in asthma: Systematic review.

Francisco CO, Bhatawadekar SA, Babineau J, et al.

PloS one 2018; (13(10)):e0204953 doi:10.1371/journal.pone.0204953.

Current opinions for the management of asthma associated with ear, nose and throat comorbidities.

Tiotiu A, Plavec D, Novakova S, et al.

European respiratory review : an official journal of the European Respiratory Society 2018; (27(150)) doi:10.1183/16000617.0056-2018.

Management of acute loss of asthma control: yellow zone strategies.

Polk BI, Dinakar C

Current opinion in allergy and clinical immunology 2019; (19(2)):154-160 doi:10.1097/ACI.0000000000000512.

Clinical Factors Associated With Overuse of Asthma Reliever Medication.

Urrutia I, Delgado J, Domínguez-Ortega J, et al.

Journal of investigational allergology & clinical immunology 2020; (30(1)):42-48 doi:10.18176/jiaci.0387.

Repeated exacerbation of asthma: An intrinsic phenotype of uncontrolled asthma.

Jain N, Satish K, Abhyankar N, et al.

Lung India : official organ of Indian Chest Society 2019; (36(2)):131-138 doi:10.4103/lungindia.lungindia_434_17.

Nocturnal symptoms perceived as asthma are associated with obstructive sleep apnoea risk, but not bronchial hyper-reactivity.

Senaratna CV, Walters EH, Hamilton G, et al.

Respirology (Carlton, Vic.) 2019; (24(12)):1176-1182 doi:10.1111/resp.13576.

Obstructive Sleep Apnea in Bronchial Asthma Patients: Assessment of Prevalence and Risk Factors.

Dixit R, Verma S, Gupta N, et al.

The Journal of the Association of Physicians of India 2018; (66(9)):45-48.

Acute severe asthma (status asthmaticus).

Agnihotri NT, Saltoun C

Allergy and asthma proceedings 2019; (40(6)):406-409 doi:10.2500/aap.2019.40.4258.

Nocturnal bilevel positive airway pressure for the treatment of asthma.

Owens RL, Campana LM, Foster AM, et al.

Respiratory physiology & neurobiology 2020; (274()):103355 doi:10.1016/j.resp.2019.103355.

Asthma and Obstructive Sleep Apnea Overlap: What Has the Evidence Taught Us?

Prasad B, Nyenhuis SM, Imayama I, et al.

American journal of respiratory and critical care medicine 2020; (201(11)):1345-1357 doi:10.1164/rccm.201810-1838TR.

The need for clean air: The way air pollution and climate change affect allergic rhinitis and asthma.

Eguiluz-Gracia I, Mathioudakis AG, Bartel S, et al.

Allergy 2020; (75(9)):2170-2184 doi:10.1111/all.14177.

Asthma maintenance and reliever therapy: Should this be the standard of care?

Cusack RP, Satia I, O'Byrne PM

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2020; (125(2)):150-155 doi:10.1016/j.anai.2020.04.009.

Relationship between biometeorological factors and the number of hospitalizations due to asthma.

Romaszko-Wojtowicz A, Cymes I, Dragańska E, et al.

Scientific reports 2020; (10(1)):9593 doi:10.1038/s41598-020-66746-8.

Disease control in patients with asthma and respiratory symptoms (wheezing, cough) during sleep.

Doenges J, Kuckuck E, Cassel W, et al.

Asthma research and practice 2020; (6()):9 doi:10.1186/s40733-020-00062-w.

Laryngeal Dysfunction in Severe Asthma: A Cross-Sectional Observational Study.

Vertigan AE, Kapela SL, Gibson PG

The journal of allergy and clinical immunology. In practice 2021; (9(2)):897-905 doi:10.1016/j.jaip.2020.09.034.

Acute severe asthma: management and treatment.

Bosi A, Tonelli R, Castaniere I, et al.

Minerva medica 2021; (112(5)):605-614 doi:10.23736/S0026-4806.21.07372-9.

Evaluation and Management of Adults with Obstructive Sleep Apnea Syndrome.

Lee JJ, Sundar KM

Lung 2021; (199(2)):87-101 doi:10.1007/s00408-021-00426-w.

The Relevance of Small Airway Dysfunction in Asthma with Nocturnal Symptoms.

Abdo M, Trinkmann F, Kirsten AM, et al.

Journal of asthma and allergy 2021; (14()):897-905 doi:10.2147/JAA.S313572.

Randomised trials of proton pump inhibitors for gastro-oesophageal reflux disease in patients with asthma: an updated systematic review and meta-analysis.

Zheng Z, Luo Y, Li J, Gao J

BMJ open 2021; (11(8)):e043860 doi:10.1136/bmjopen-2020-043860.

The endogenous circadian system worsens asthma at night independent of sleep and other daily behavioral or environmental cycles.

Scheer FAJL, Hilton MF, Evoniuk HL, et al.

Proceedings of the National Academy of Sciences of the United States of America 2021; (118(37)) doi:10.1073/pnas.2018486118.

Melatonin MT2 receptor is expressed and potentiates contraction in human airway smooth muscle.

Sasaki H, Zhang Y, Emala CW, Mizuta K

American journal of physiology. Lung cellular and molecular physiology 2021; (321(6)):L991-L1005 doi:10.1152/ajplung.00273.2021.

A Practical Guide to Implementing SMART in Asthma Management.

Reddel HK, Bateman ED, Schatz M, et al.

The journal of allergy and clinical immunology. In practice 2022; (10(1S)):S31-S38 doi:10.1016/j.jaip.2021.10.011.

Global Initiative for Asthma Strategy 2021: Executive Summary and Rationale for Key Changes.

Reddel HK, Bacharier LB, Bateman ED, et al.

Respirology (Carlton, Vic.) 2022; (27(1)):14-35 doi:10.1111/resp.14174.

Global Initiative for Asthma Strategy 2021: Executive Summary and Rationale for Key Changes.

Reddel HK, Bacharier LB, Bateman ED, et al.

The journal of allergy and clinical immunology. In practice 2022; (10(1S)):S1-S18 doi:10.1016/j.jaip.2021.10.001.

Diagnostic and Therapeutic Outcomes Following Systematic Assessment of Patients with Concurrent Suspected Vocal Cord Dysfunction and Asthma.

Stojanovic S, Denton E, Lee J, et al.

The journal of allergy and clinical immunology. In practice 2022; (10(2)):602-608.e1 doi:10.1016/j.jaip.2021.10.038.

The effects of nebulized ketamine and intravenous magnesium sulfate on corticosteroid resistant asthma exacerbation; a randomized clinical trial.

Farshadfar K, Sohooli M, Shekouhi R, et al.

Asthma research and practice 2021; (7(1)):15 doi:10.1186/s40733-021-00081-1.

Primary Care Management of Asthma Exacerbations or Attacks: Impact of the COVID-19 Pandemic.

Fletcher M, van der Molen T, Lenney W, et al.

Advances in therapy 2022; (39(4)):1457-1473 doi:10.1007/s12325-022-02056-x.

European Respiratory Society guidelines for the diagnosis of asthma in adults.

Louis R, Satia I, Ojanguren I, et al.

The European respiratory journal 2022; (60(3)) doi:10.1183/13993003.01585-2021.

Evaluation of Budesonide-Formoterol for Maintenance and Reliever Therapy Among Patients With Poorly Controlled Asthma: A Systematic Review and Meta-analysis.

Beasley R, Harrison T, Peterson S, et al.

JAMA network open 2022; (5(3)):e220615 doi:10.1001/jamanetworkopen.2022.0615.

Annual and Post-Exacerbation Follow-Up of Asthma Patients in Clinical Practice - A Large Population-Based Study in Sweden.

Sandelowsky H, Ställberg B, Wiklund F, et al.

Journal of asthma and allergy 2022; (15()):475-486 doi:10.2147/JAA.S357086.

Asthma and asthma-related comorbidity: effects on nocturnal oxygen saturation.

Sundbom F, Janson C, Ljunggren M, Lindberg E

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2022; (18(11)):2635-2641 doi:10.5664/jcsm.10178.

Differences in L-arginine metabolism and asthma morbidity among asthma patients with and without obstructive sleep apnea.

Althoff MD, Jimenez G, Peterson R, et al.

Respiratory research 2022; (23(1)):230 doi:10.1186/s12931-022-02157-9.

Predictive factors for obstructive sleep apnea in adults with severe asthma receiving biologics: a single-center cross-sectional study.

Araujo AMS, Duarte RLM, Gozal D, et al.

Sleep & breathing = Schlaf & Atmung 2023; (27(3)):1091-1098 doi:10.1007/s11325-022-02710-2.

Determinants of Severe Asthma - A Long-Term Cohort Study in Northern Sweden.

Backman H, Stridsman C, Hedman L, et al.

Journal of asthma and allergy 2022; (15()):1429-1439 doi:10.2147/JAA.S376806.

BMAL1/FOXA2-induced rhythmic fluctuations in IL-6 contribute to nocturnal asthma attacks.

Tang L, Liu L, Sun X, et al.

Frontiers in immunology 2022; (13()):947067 doi:10.3389/fimmu.2022.947067.

Short-term exposure to ozone and asthma exacerbation in adults: A longitudinal study in China.

Fang X, Huang S, Zhu Y, et al.

Frontiers in public health 2022; (10()):1070231 doi:10.3389/fpubh.2022.1070231.

Small airway dysfunction in asthmatic patients treated with as-needed SABA monotherapy: A perfect storm.

Cottini M, Lombardi C, Comberiati P, et al.

Respiratory medicine 2023; (209()):107154 doi:10.1016/j.rmed.2023.107154.

AGA Clinical Practice Update on the Diagnosis and Management of Extraesophageal Gastroesophageal Reflux Disease: Expert Review.

Chen JW, Vela MF, Peterson KA, Carlson DA

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2023; (21(6)):1414-1421.e3 doi:10.1016/j.cgh.2023.01.040.

Impulse oscillometry defined small airway dysfunction in asthmatic patients with normal spirometry: Prevalence, clinical associations, and impact on asthma control.

Cottini M, Bondi B, Bagnasco D, et al.

Respiratory medicine 2023; (218()):107391 doi:10.1016/j.rmed.2023.107391.

Do nocturnal asthma attacks influence sleep parameters and inflammatory markers? A cross-sectional population-based study.

Souza MR, Rosa DS, Alvarenga TA, et al.

Sleep & breathing = Schlaf & Atmung 2024; (28(2)):619-627 doi:10.1007/s11325-023-02935-9.

Adherence to National Asthma Guidelines in the Acute Care Setting: A Retrospective Cohort Study.

Hussain M, Hassan T, Hussain G, et al.

Cureus 2023; (15(11)):e48725 doi:10.7759/cureus.48725.

Allergic rhinitis and other comorbidities associated with asthma control in Thailand.

Sriprasart T, Saiphoklang N, Kawamatawong T, et al.

Frontiers in medicine 2023; (10()):1308390 doi:10.3389/fmed.2023.1308390.

The prevalence of obstructive sleep apnea in Japanese asthma patients.

Yasuda M, Tobino K, Harada N, et al.

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 2024; (20(1)):10 doi:10.1186/s13223-024-00875-x.

What is the Best Way to Diagnose Possible Asthma Patients with Negative Bronchodilator Reversibility Tests?

Başa Akdoğan B, Koca Kalkan I, Köycü Buhari G, et al.

Journal of asthma and allergy 2024; (17()):113-122 doi:10.2147/JAA.S437756.

APPaRENT 3: Asthma Patients' and Physicians' Perspectives on the Burden and Management of Asthma in Seven Countries.

Aggarwal B, Al-Moamary M, Allehebi R, et al.

Advances in therapy 2024; (41(8)):3089-3118 doi:10.1007/s12325-024-02900-2.

Diurnal variation in asthma symptoms: Exploring the role of melatonin.

Sasaki H, Mizuta K

Journal of oral biosciences 2024; (66(3)):519-524 doi:10.1016/j.job.2024.06.008.

Inhaled Reliever Therapies for Asthma: A Systematic Review and Meta-Analysis.

Rayner DG, Ferri DM, Guyatt GH, et al.

JAMA 2025; (333(2)):143-152 doi:10.1001/jama.2024.22700.

Successful Treatment of Refractory Status Asthmaticus With Veno-Venous Extracorporeal Membrane Oxygenation (VV ECMO): A Case Report.

Tan L, Thornton I

Cureus 2025; (17(2)):e78672 doi:10.7759/cureus.78672.

Effects of rostral fluid shift on small airway narrowing in asthma before and after bronchodilation.

Cao X, Francisco CO, TaghiBeyglou B, et al.

Sleep & breathing = Schlaf & Atmung 2026; (30(1)):53.

Association between nocturnal asthma, symptom severity, and clinical outcomes: a systematic review.

Tachinardi P, Callado GY, Ferreira JMG, et al.

The Journal of asthma : official journal of the Association for the Care of Asthma 2026; (63(10)):1181-1188 doi:10.1080/02770903.2026.2660319.

AIR and MART approach to asthma treatment.

Bhugra R

Drug and therapeutics bulletin 2026; (64(7)):108-111 doi:10.1136/dtb.2023.000058.

Beta2-agonist and anti-inflammatory combination therapy for asthma rescue: a paradigm shift in asthma care.

Skolnik N, Stieritz J, Akers J, et al.

Frontiers in medicine 2026; (13()):1826737 doi:10.3389/fmed.2026.1826737.

Circadian-guided asthma therapy: compressed-coated chronotherapeutic tablets for precision early-morning drug delivery.

Sindhu K, Kumar P, Kumar A, et al.

Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 2026; (34(2)).

Current perspectives on β2-adrenergic receptor agonists in asthma: navigating from track to track within GINA recommendations.

Calzetta L, Rogliani P

Expert opinion on pharmacotherapy 2026; (27(11)):1085-1095 doi:10.1080/14656566.2026.2702385.