Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
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Yale University
New Haven, United States
Washington University in St. Louis
St Louis, United States
Erasmus MC
Rotterdam, The Netherlands
Children's Hospital of Philadelphia
Philadelphia, United States
Children's National
Washington, United States
Great Ormond Street Hospital
London, United Kingdom
University of New Haven
West Haven, United States
The Kids Research Institute Australia
West Perth, Australia
Heidelberg University
Heidelberg, Germany
Boston Children's Hospital
Boston, United States
References
References (50)
- 1
What's in a Name? Accurately Diagnosing Metopic Craniosynostosis Using a Computational Approach.
Wood BC, Mendoza CS, Oh AK, et al.
Plastic and reconstructive surgery 2016; (137(1)):205-213 doi:10.1097/PRS.0000000000001938.
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Objective Assessment of the Interfrontal Angle for Severity Grading and Operative Decision-Making in Metopic Synostosis.
Anolik RA, Allori AC, Pourtaheri N, et al.
Plastic and reconstructive surgery 2016; (137(5)):1548-1555 doi:10.1097/PRS.0000000000002052.
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Children with Metopic Ridge.
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Turkish neurosurgery 2017; (27(4)):585-589 doi:10.5137/1019-5149.JTN.16886-15.2.
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Identical Twins Discordant for Metopic Craniosynostosis: Evidence of Epigenetic Influences.
Magge SN, Snyder K, Sajja A, et al.
The Journal of craniofacial surgery 2017; (28(1)):14-16 doi:10.1097/SCS.0000000000003368.
PMID: 28060197 - 5
The Severity of Deformity in Metopic Craniosynostosis Is Correlated with the Degree of Neurologic Dysfunction.
Yang JF, Brooks ED, Hashim PW, et al.
Plastic and reconstructive surgery 2017; (139(2)):442-447 doi:10.1097/PRS.0000000000002952.
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Current Controversies in Metopic Suture Craniosynostosis.
Jaskolka MS
Oral and maxillofacial surgery clinics of North America 2017; (29(4)):447-463 doi:10.1016/j.coms.2017.07.003.
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Clinical Evaluation of Standardized Fronto-Orbital Advancement for Correction of Isolated Trigonocephaly.
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The Journal of craniofacial surgery 2018; (29(1)):72-75 doi:10.1097/SCS.0000000000004058.
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Safety Outcomes in Endoscopic Versus Open Repair of Metopic Craniosynostosis.
Braun TL, Eisemann BS, Olorunnipa O, et al.
The Journal of craniofacial surgery 2018; (29(4)):856-860 doi:10.1097/SCS.0000000000004299.
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Cognitive, behavioral and psychological functioning in children with metopic synostosis: a meta-analysis examining the impact of surgical status.
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Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence 2019; (25(2)):263-277 doi:10.1080/09297049.2018.1441821.
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Physiologic closure time of the metopic suture in South Australian infants from 3D CT scans.
Teager SJ, Constantine S, Lottering N, Anderson PJ
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2019; (35(2)):329-335 doi:10.1007/s00381-018-3957-9.
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Discussion: Long-Term Results in Isolated Metopic Synostosis: The Oxford Experience over 22 Years.
Gilardino MS
Plastic and reconstructive surgery 2018; (142(4)):516e-517e doi:10.1097/PRS.0000000000004769.
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Investigating the cause of late deformity following fronto-orbital remodelling for metopic synostosis using 3D CT imaging.
Rodriguez-Florez N, Florez-Tapia A, Jeelani NUO, et al.
Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 2019; (47(1)):170-178 doi:10.1016/j.jcms.2018.11.008.
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Shifting epidemiology of single-suture craniosynostosis and the need for a more granular ICD classification system: a national survey of members from the American Society of Pediatric Neurosurgeons (ASPN) and the American Society of Craniofacial Surgeons (ASCFS).
Gonzalez SR, Han A, Golinko MS
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2019; (35(9)):1443-1444 doi:10.1007/s00381-019-04223-y.
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The metopic suture: Natural history.
Vinchon M
Neuro-Chirurgie 2019; (65(5)):239-245 doi:10.1016/j.neuchi.2019.09.006.
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School-Aged Anthropometric Outcomes After Endoscopic or Open Repair of Metopic Synostosis.
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Pediatrics 2020; (146(3)) doi:10.1542/peds.2020-0238.
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Quantitative outcomes of endoscopic strip craniectomy for metopic craniosynostosis in children with severe trigonocephaly.
Lajthia O, Rogers GF, Tsering D, et al.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2021; (37(2)):573-579 doi:10.1007/s00381-020-04849-3.
PMID: 32812117 - 17
Increased Incidence of Ophthalmologic Findings in Children With Concurrent Isolated Nonsyndromic Metopic Suture Abnormalities and Deformational Cranial Vault Asymmetry.
Roider L, Ungerer G, Shock L, et al.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2021; (58(4)):497-504 doi:10.1177/1055665620954739.
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Emissary veins and pericerebral cerebrospinal fluid in trigonocephaly: do they define a specific subtype?
Di Rocco F, Garcia-Gonzalez O, Szathmari A, et al.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2021; (37(4)):1159-1165 doi:10.1007/s00381-020-04982-z.
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Three-dimensional photography for intraoperative morphometric analysis in metopic craniosynostosis surgery.
García-Mato D, García-Sevilla M, Porras AR, et al.
International journal of computer assisted radiology and surgery 2021; (16(2)):277-287 doi:10.1007/s11548-020-02301-0.
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Distinguishing craniomorphometric characteristics and severity in metopic synostosis patients.
Chandler L, Park KE, Allam O, et al.
International journal of oral and maxillofacial surgery 2021; (50(8)):1040-1046 doi:10.1016/j.ijom.2020.11.022.
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Photogrammetric evaluation of corrective surgery for trigonocephaly.
Kuehle R, Ewerbeck N, Rückschloß T, et al.
International journal of oral and maxillofacial surgery 2022; (51(1)):70-77 doi:10.1016/j.ijom.2021.06.003.
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Establishment of Objective Clinical Parameters for Assessment of Trigonocephaly: Are Caliper-Derived Clinical Measures Adequate?
Yan Y, McGrath JL, Janes LE, Gosain AK
The Journal of craniofacial surgery 2022; (33(1)):259-263 doi:10.1097/SCS.0000000000008061.
PMID: 34334742 - 23
Outcomes of Surgical Management of Metopic Synostosis : A Retrospective Study of 18 Cases.
Elhawary ME, Adawi M, Gabr M
Journal of Korean Neurosurgical Society 2022; (65(1)):107-113 doi:10.3340/jkns.2021.0034.
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The Clinical Dilemma of Autism Spectrum Disorder Diagnosis in a Child with 9p Deletion.
Karba BE, Lemay JF, McLeod SA
Journal of pediatric genetics 2021; (10(3)):250-252 doi:10.1055/s-0040-1713431.
PMID: 34504731 - 25
Rate of craniometric change following suture release in patients with metopic and sagittal craniosynostosis.
Leclair NK, Lambert WA, Knopf J, et al.
Journal of neurosurgery. Pediatrics 2022; (29(1)):66-73 doi:10.3171/2021.7.PEDS21239.
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Epidemiology of Rare Craniofacial Anomalies: Retrospective Western Australian Population Data Linkage Study.
Junaid M, Slack-Smith L, Wong K, et al.
The Journal of pediatrics 2022; (241()):162-172.e9 doi:10.1016/j.jpeds.2021.09.060.
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Cerebral Blood Flow of the Frontal Lobe in Untreated Children with Trigonocephaly versus Healthy Controls: An Arterial Spin Labeling Study.
de Planque CA, Petr J, Gaillard L, et al.
Plastic and reconstructive surgery 2022; (149(4)):931-937 doi:10.1097/PRS.0000000000008931.
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A new method for quantification of frontal retrusion and complex skull shape in metopic craniosynostosis: a pilot study of a new outcome measure for endoscopic strip craniectomy.
Sakar M, Haidar H, Sönmez Ö, et al.
Journal of neurosurgery. Pediatrics 2022; (29(6)):650-658 doi:10.3171/2022.1.PEDS21553.
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A Diffusion Tensor Imaging Analysis of Frontal Lobe White Matter Microstructure in Trigonocephaly Patients.
de Planque CA, Gaillard L, Vrooman HA, et al.
Pediatric neurology 2022; (131()):42-48 doi:10.1016/j.pediatrneurol.2022.04.003.
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Trigonocephaly: Quantitative Comparison of the Complete Vault Reconstruction and Minimally Invasive Suturectomy.
Masoudi MS, Yousefi S, Yousefi O, et al.
World neurosurgery 2022; (166()):e77-e83 doi:10.1016/j.wneu.2022.06.093.
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Management of Unicoronal and Metopic Synostoses: Minimally Invasive Approaches.
Hayek GM, Jimenez DF, Yates DM
Oral and maxillofacial surgery clinics of North America 2022; (34(3)):381-394 doi:10.1016/j.coms.2022.02.002.
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The Craniofacial Collaboration UK: Developmental Outcomes in 5-Year-Old Children With Metopic Synostosis.
Edwards-Bailey L, Piggott K, Dalton L, et al.
The Journal of craniofacial surgery 2023; (34(3)):855-859 doi:10.1097/SCS.0000000000009095.
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Clinical interest of molecular study in cases of isolated midline craniosynostosis.
Di Rocco F, Rossi M, Verlut I, et al.
European journal of human genetics : EJHG 2023; (31(6)):621-628 doi:10.1038/s41431-023-01295-y.
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Long-term neurocognitive outcomes in 204 single-suture craniosynostosis patients.
Junn AH, Long AS, Hauc SC, et al.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2023; (39(7)):1921-1928 doi:10.1007/s00381-023-05908-1.
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Is endoscope-assisted strip craniectomy the future of metopic suture craniosynostosis treatment? An 11-year experience with 62 patients.
Agushi R, Scagnet M, Spacca B, et al.
Journal of neurosurgery. Pediatrics 2023; (32(1)):75-81 doi:10.3171/2023.2.PEDS22409.
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Eye and Orbital Anatomy in Metopic Synostosis.
Gaillard L, Puppels AE, Dremmen MHG, et al.
Plastic and reconstructive surgery. Global open 2023; (11(10)):e5303 doi:10.1097/GOX.0000000000005303.
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Comparison of emotional and behavioral regulation between metopic and sagittal synostosis.
Almeida MN, Alper DP, Parikh N, et al.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2024; (40(9)):2789-2799 doi:10.1007/s00381-024-06387-8.
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New diagnostic criteria for metopic ridges and trigonocephaly: a 3D geometric approach.
Bloch K, Geoffroy M, Taverne M, et al.
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Radiographic severity is associated with worse executive function in metopic craniosynostosis.
Almeida MN, Alper DP, Barrero C, et al.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2024; (40(12)):3971-3982 doi:10.1007/s00381-024-06493-7.
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Using a new analytic approach for genotyping and phenotyping chromosome 9p deletion syndrome.
Starosta RT, Jensen N, Couteranis S, et al.
European journal of human genetics : EJHG 2024; (32(9)):1095-1105 doi:10.1038/s41431-024-01667-y.
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Dura-based automated vault expansion remodelling (DAVE-R): automated planning of volume expansion in fronto-orbital advancement for trigonocephaly.
Dapaah A, Duncan C, Parks C, et al.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2024; (40(12)):4003-4011 doi:10.1007/s00381-024-06608-0.
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Orthoptic findings in trigonocephaly patients after completed visual development.
Yang S, Gaillard L, den Ottelander BK, et al.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2024; (41(1)):8 doi:10.1007/s00381-024-06657-5.
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Craniosynostosis: Quantifying Differences in Skull Architecture.
Menville JE, Shinde N, Collins S, et al.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2026; (63(1)):38-48 doi:10.1177/10556656241297526.
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Distal 1q Duplication and Distal 9p Deletion: A Follow-Up Case Report and Literature Review on Candidate Genes for 9p Deletion Syndrome.
Helbig J, Kunz J, Mannhardt A, et al.
American journal of medical genetics. Part A 2025; (197(8)):e64066 doi:10.1002/ajmg.a.64066.
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Long-term health-related quality of life and satisfaction following fronto-orbital advancement in non-syndromic metopic synostosis: FACE-Q Craniofacial Module and SCAR-Q.
Tio PAE, Koehoorn E, Pleumeekers MM, et al.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS 2025; (111()):43-52 doi:10.1016/j.bjps.2025.10.003.
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Spring-Assisted Cranioplasty for Metopic Craniosynostosis: Perioperative Metrics in Comparison to Fronto-Orbital Advancement and Strip Craniectomy.
Lee RS, Girian S, Baker C, et al.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2026; (63(3)):370-375 doi:10.1177/10556656251403083.
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Long-term cranial shape outcomes in metopic synostosis: A 12-year follow-up study using 3D photography.
Claessens N, Breakey W, Penington A, et al.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS 2026; (113()):568-574 doi:10.1016/j.bjps.2025.12.001.
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Evaluating long-term outcomes of fronto-orbital advancement in metopic synostosis: insights from 3D photogrammetry.
Tio PAE, Mathijssen IMJ, van Veelen MC, et al.
Plastic and reconstructive surgery 2025; doi:10.1097/PRS.0000000000012739.
PMID: 41467720 - 49
Neurocognitive and behavioral outcomes in metopic synostosis: relation to severity and surgical timing.
Tio PAE, van Staalduinen MJA, Dulfer K, et al.
Plastic and reconstructive surgery 2026; doi:10.1097/PRS.0000000000012842.
PMID: 41568980 - 50
Incidence of Ocular Abnormalities in Metopic Craniosynostosis: Cranial Vault Reconstruction Versus Endoscopic Suturectomy.
Ha JY, Doh S, Tomei KL, et al.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2026; 10556656261417870 doi:10.1177/10556656261417870.
PMID: 41632637